Internal Facilitation by Health Assistants for the “WHO Lay Health Worker Dementia Care” in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Edith K Wakida,1,2 Celestino Obua,2 Godfrey Zari Rukundo,3 Mary Samantha,2 Samuel Maling,4 Christine K Karungi,2 Zohray M Talib,1 Jessica Haberer,5,6 Stephen J Bartels5,6 1Department of Medical Education, California University of Science and Medicine, Colton, California, USA; 2Department of Research and Development, Alpha Center for Research Administration, Mbarara, Uganda; 3Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada; 4Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda; 5Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; 6Harvard Medical School, Harvard University, Boston, Massachusetts, USACorrespondence: Edith K Wakida, Email Edith.Wakida@cusm.eduBackground: Dementia is characterized by cognitive symptoms like memory loss, difficulty with language, and impaired judgment, alongside behavioral and psychological symptoms such as depression, anxiety, and aggression. Early diagnosis and tailored care are essential for managing these symptoms, improving quality of life, and reducing caregiver burden. …”
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The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

“…In our study, the potential of miRNAs as a biomarker in the diagnosis and treatment of DCM was evaluated in the diabetes model induced by streptozotocin in rats. …”
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sB7H3 in Children with Acute Appendicitis: Its Diagnostic Value and Association with Histological Findings by Xiaochen Du, Yan Chen, Jie Zhu, Zhenjiang Bai, Jun Hua, Ying Li, Haitao Lv, Guangbo Zhang

“…Several efforts have been made to find out a valuable marker to assist the diagnosis and differentiation of gangrenous/perforated appendicitis. …”
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Prevalence of sexually transmitted infections and associated factors among male prisoners in Great Tehran Prison by active case finding by Behnam Farhoudi, Elnaz Shahmohamadi, Seyedahmad Seyedalinaghi, SeyedAlireza Nadji, Fatemeh Pahlaviani, Mehrzad Tashakorian

“…They were examined by complete genital and anal examination, followed by molecular testing for a definite diagnosis. The mean age of participants was 33.4 years. …”
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Economic evaluation of a randomized controlled trial comparing mifepristone and misoprostol with misoprostol alone in the treatment of early pregnancy loss. by Charlotte C Hamel, Marcus P L M Snijders, Sjors F P J Coppus, Frank P H A Vandenbussche, Didi D M Braat, Eddy M M Adang

“…We included 351 women with a diagnosis of EPL between 6 and 14 weeks gestation after at least one week of unsuccessful expectant management. …”
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Screening of COPD patients using the COPD diagnostic questionnaire and a portable spirometer in primary healthcare institutions: a cross-sectional, diagnostic study by Feng Chen, Qingrong Nie, Xuefeng Han, Chunjuan Li, Qimeng Liu, Feifei Xu, Li Zhang, Le Qiao, Maoxin Li, Ying Zhang, Haiyan Wang

“…The area under the ROC curve for the combined diagnosis of COPD was 0.994 (95% CI: 0.983–0.999), with a Jordan index of 0.765. …”
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Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease by Cristine de Paula Nascimento-Castro, Ana Claudia Wink, Victor Silva da Fônseca, Claudia Daniele Bianco, Elisa C. Winkelmann-Duarte, Marcelo Farina, Ana Lúcia S. Rodrigues, Joana Gil-Mohapel, Andreza Fabro de Bem, Patricia S. Brocardo

“…Depression is one of the most common psychiatric disturbances in HD, present even before manifestation of motor symptoms. Diagnosis and treatment of depression in HD-affected individuals are essential aspects of clinical management in this population, especially owing to the high risk of suicide. …”
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Predictors of failure of DISE-directed adenotonsillectomy in children with sleep disordered breathing by Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major, Hamdy El-Hakim

“…On bivariate analysis, neuropsychiatric diagnosis (r = 0.286, p = 0.042), history of sleepwalking or enuresis (r = 0.103, p = 0.044), MOS (r = 0.123, p = 0.033), presence of DNS (r = 0.107, p = 0.036), and presence of laryngomalacia (r = 0.122, p = 0.017) all positively correlated with treatment failure. …”
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Patient characteristics and predictors of mortality among children hospitalised with tuberculosis: A six-year case series study in Uganda. by Pauline Mary Amuge, Greta Lassance Becker, Rogers Nelson Ssebunya, Esther Nalumansi, Alex Adaku, Michael Juma, Jay Brooks Jackson, Adeodata Rukyarekere Kekitiinwa, Peter James Elyanu, Eric Wobudeya, Robert Blount

“…The high in-hospital mortality and long hospital stay may be reduced by timely TB diagnosis and treatment initiation among children.…”
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Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample by Raja Zaghlol, Amit K. Dey, Sameer Desale, Ana Barac

“…Patients with a primary diagnosis of acute coronary syndrome were excluded to reduce selection bias. …”
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A Review on the Nomenclature and Taxonomy of the Old World Thread-Legged Bug Genus <i>Pleias</i> (Hemiptera: Reduviidae: Emesinae) by Zhuo Chen, Hu Li, Wanzhi Cai

“…The bibliographies, diagnosis, and known distribution records are presented for all described species, and three new species [<i>P. fashengi</i><b>sp. n.…”
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Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings by Abdullahi Tunde Aborode, Ridwan Olamilekan Adesola, Godfred Yawson Scott, Emele Arthur-Hayford, Oche Joseph Otorkpa, Somuah Daniel Kwaku, Emmanuel Ebuka Elebesunu, Eghaghe Osadebamwen Nibokun, Ibude Jane Aruorivwooghene, Adetolase A. Bakre, Oluwaseun Adeolu Ogundijo, Olamilekan Gabriel Banwo, Oluwatobiloba Ige, Ibrahim O. Adelakun, Isreal Ayobami Onifade, Segun E. Ogungbemi, Boluwatife T. Dosunmu, Oluwaseunayo Deborah Ayando, Nike Idowu, Grace A. Adegoye, Olusegun Oluwaseun Jimoh

“…These advancements aim to provide faster diagnosis, better medical care, and ongoing monitoring in areas where traditional diagnostic methods are not practical, combining the precision of laboratory testing with the accessibility of field-based solutions. …”
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Reconstitution of pluripotency from mouse fibroblast through Sall4 overexpression by Lizhan Xiao, Zifen Huang, Zixuan Wu, Yongzheng Yang, Zhen Zhang, Manish Kumar, Haokaifeng Wu, Huiping Mao, Lihui Lin, Runxia Lin, Jingxian Long, Lihua Zeng, Jing Guo, Rongping Luo, Yi Li, Ping Zhu, Baojian Liao, Luqin Wang, Jing Liu

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Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC by Kai-Xia Zhou, Shan Huang, Li-Peng Hu, Xue-Li Zhang, Wei-Ting Qin, Yan-Li Zhang, Lin-Li Yao, Yanqiu Yu, Yao-Qi Zhou, Lei Zhu, Jianguang Ji, Zhi-Gang Zhang

“…Collectively, our data suggested that KPNA2 has the potential to serve as a promising biomarker for diagnosis in PDAC.…”
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Clinical Aspects and Prognosis Evaluation of Cirrhotic Patients Hospitalized with Acute Kidney Injury by Célio Geraldo de Oliveira Gomes, Marcus Vinicius Melo de Andrade, Ludmila Resende Guedes, Henrique Carvalho Rocha, Roberto Gardone Guimarães, Fernando Antônio Castro Carvalho, Eduardo Garcia Vilela

“…Clinical and laboratory data was collected at diagnosis between 2011 and 2015. Results. Average age was 54.6 (±10.7) years and 69.2% were male. …”
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Ethnobotany, floristic and phytochemical studies of medicinal plants used to treat uterine fibroids in Mbarara City, Uganda by Calton Nantinda, Esther Lynnet Kisakye, David Musana, Isaac Ssessanga, Ukashar Ssenabulya, Timothy Omara, Ivan Kahwa, Florence Nalimu

“…Our results indicated that most TMPs knew about UF and valued conventional means of diagnosis before initiating herbal treatment. Forty-seven (47) plant species belonging to 32 families and 45 genera were identified. …”
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Increasing incidences and changes in treatment trends of clavicle fractures in adults during 2 decades in Denmark: a nationwide study on data from the Danish National Patient Regis... by Ida Tryggedsson, Bjarke Viberg, Per Hviid Gundtoft, Ilija Ban, Søren Overgaard, Tazio Maleitzke, Arvind von Keudell

“…Methods: The Danish National Patient Register was used to extract data on clavicle fracture diagnosis and treatment in patients aged 18 and above from 1996 to 2018. …”
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Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors by Yunbi Liu, Wei Yang, Guangnan She, Liming Zhong, Zhaoqiang Yun, Yang Chen, Ni Zhang, Liwei Hao, Zhentai Lu, Qianjin Feng, Wufan Chen

“…The proposed method can markedly reduce the visibility of bony structures in chest radiographs and shows potential to enhance diagnosis.…”
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The association between tobacco and alcohol use and health outcomes in individuals living with diabetes and prediabetes in South Africa: A cross-sectional study by S J Mulder, T Chivese, C O Egbe

“…Participants were classified into prediabetes or T2DM groups, based on a glycated haemoglobin cut-off of 5.7% or self-report of a previous diagnosis of T2DM. Exposures of interest were self-reported current tobacco smoking and problem/risky alcohol use. …”
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Health Services Availability and Readiness for Management of Hypertension and Diabetes in Primary Care Health Facilities in Ghana: a Cardiovascular Risk Management project by Thomas Hinneh, Bernard Mensah, Hosea Boakye, Oluwabunmi Ogungbe, Yvonne Commodore-Mensah

“…Timely screening and diagnosis at primary health facilities are crucial to initiate treatment and avert complications. …”
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