Modelling chemistry and biology after implantation of a drug-eluting stent. Part Ⅰ: Drug transport by Tuoi Vo, William Lee, Adam Peddle, Martin Meere

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The significance of isolated de novo red patches in the bladder in patients referred with suspected urinary tract cancer: Results from the IDENTIFY study by Sinan Khadhouri, Kevin Gallagher, Kenneth R. MacKenzie, Taimur T. Shah, Chuanyu Gao, Eleanor Zimmermann, Miles Mannas, Taeweon Lee, Giancarlo Marra, Juan Gomez Rivas, Gautier Marcq, Mark A. Assmus, Taha Ucar, Francesco Claps, Matteo Boltri, Giuseppe Pizzuto, Tara Burnhope, Nkwam Nkwam, George Tanasescu, Nicholas E. Boxall, Alison P. Downey, Troy A. Sukhu, Marta Antón‐Juanilla, Sonpreet Rai, Madeline Moore, Kathryn Bandeira de Mello, Sian Parsons, John S. McGrath, Veeru Kasivisvanathan, IDENTIFY Study Group: Pubmed indexed collaborator authors

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Solid-state mantle convection coupled with a crystallising basal magma ocean by Labrosse, Stéphane, Morison, Adrien, Tackley, Paul James

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Exploring perceived barriers to palliative and end of life care provision in South-West England: bringing together the perspectives of professionals, patients, and families by Gary Hodge, Gina Kallis, Tomasina M. Oh, Hannah Wheat, Susie Pearce, Susie Pearce

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A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT) by Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter

“…Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A semi-structured qualitative interview design was used, with data analysed using the framework approach.Participants 20 participants with anhedonic depression who had received up to 20 sessions of ADepT, sampled from a pilot randomised controlled trial of ADepT versus Cognitive Behavioural Therapy (CBT).Setting A primary care psychological therapy clinic in Devon, UK, with interviews occurring between May 2018 and February 2020.Results Participants found the wellbeing focus of ADepT acceptable. …”
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Use of computerised adaptive testing to reduce the number of items in patient-reported hip and knee outcome scores: an analysis of the NHS England National Patient-Reported Outcome... by Jose Maria Valderas, Andrew D Toms, Jonathan Peter Evans, Christopher Gibbons

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Routes to social prescribing outside National Health Service (NHS) structures: a systematic map by Kerryn Husk, Stephanie Tierney, Lucy Gavens, Emma Hazeldine, Sophie Westwood, Mohammad Hassannezhad

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Experiences of ‘traditional’ and ‘one-stop’ MRI-based prostate cancer diagnostic pathways in England: a qualitative study with patients and GPs by Fiona M Walter, Stephanie Archer, Willie Hamilton, Samuel William David Merriel, John McGrath, Alice S Forster, Hashim Uddin Ahmed, David Eldred-Evans

“…Objectives This study aimed to understand and explore patient and general practitioner (GP) experiences of ‘traditional’ and ‘one-stop’ prostate cancer diagnostic pathways in England.Design Qualitative study using semi-structured interviews, analysed using inductive thematic analysisSetting Patients were recruited from National Health Service (NHS) Trusts in London and in Devon; GPs were recruited via National Institute for Health Research (NIHR) Clinical Research Networks. …”
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Pre-gestational diabetes in a young woman with a pathogenic INSR missense mutation, p.(Met1180Lys) by Emma L Prehn, Mairéad Crowley, David Fennell, Brendan T Kinsley, Kevin Colclough, Maria M Byrne

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Supporting self-management for patients with Interstitial Lung Diseases: Utility and acceptability of digital devices. by Malik A Althobiani, Rebecca Shuttleworth, John Conway, Jonathan Dainton, Anna Duckworth, Ana Jorge Da Ponte, Jessica Mandizha, Joseph W Lanario, Michael A Gibbons, Sarah Lines, Chris J Scotton, John R Hurst, Joanna C Porter, Anne-Marie Russell

“…The survey was critically appraised by the interdisciplinary self-management group at Royal Devon University Hospitals NHS Foundation Trust during a 6-month validation process. …”
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Chemical Diversity of UK-Grown Tea Explored Using Metabolomics and Machine Learning by Amanda J. Lloyd, Alina Warren-Walker, Jasen Finch, Jo Harper, Kathryn Bennet, Alison Watson, Laura Lyons, Pilar Martinez Martin, Thomas Wilson, Manfred Beckmann

“…Background/Objectives: Dartmoor Estate Tea plantation in Devon, UK, is renowned for its unique microclimate and varied soil conditions, which contribute to the distinctive flavours and chemical profiles of tea. …”
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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

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Correction: HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

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Gaps in our understanding of ice-nucleating particle sources exposed by global simulation of the UK Earth System Model by R. J. Herbert, A. Sanchez-Marroquin, A. Sanchez-Marroquin, D. P. Grosvenor, D. P. Grosvenor, K. J. Pringle, S. R. Arnold, B. J. Murray, K. S. Carslaw

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Multi-Isotope Geochemical Baseline Study of the Carbon Management Canada Research Institutes CCS Field Research Station (Alberta, Canada), Prior to CO2 Injection by Rachel E. Utley, Emma Martin-Roberts, Nicholas Utting, Gareth Johnson, Domokos Györe, Marta Zurakowska, Finlay M. Stuart, Adrian J. Boyce, Thomas H. Darrah, Pauline Gulliver, R. Stuart Haszeldine, Don Lawton, Stuart M. V. Gilfillan

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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

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Persistent and emerging threats to Arctic biodiversity and ways to overcome them: a horizon scan by Tanya A. Lemieux, Jackson D.R. Coles, Anne L. Haley, Michelle L. LaFlamme, Sara K. Steel, Kara M. Scott, Jennifer F. Provencher, Courtney Price, Joseph R. Bennett, Isabel C. Barrio, Helen S. Findlay, Simon J. Goodman, Blake Matthews, Joacim Näslund, David. A. Pearce, Robert D. Hollister, Mark L. Mallory, Paul A. Smith, Gabriela Schaepman-Strub, Steven J. Cooke

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Response of high-yielding soybean varieties to water-saturated and drought stress by Purwantoro ., R.D. Purwaningrahayu, H. Kuntyastuti, A. Harsono, N. Nuryati, A. Sulistyo, Z. Yursak, R. Soehendi, Trustinah ., H. Kuswantoro, M.J. Mejaya, D. Harnowo

“…The soybean variety is the second factor to consider, which includes Dering 1 (known for its drought tolerance), Dering 2 (also drought tolerant), Deja 1 (tolerant to water saturation), Deja 2 (also tolerant to water saturation), Devon 1 (noted for its high isoflavone content), and Dega 1 (specifically adapted for irrigated lowland conditions).FINDINGS: The results showed that Dering 2 and Deja 2 varieties grown in soil moisture levels at 40 percent field capacity were capable of achieving similar growth outcomes in terms of plant height, shoot/root ratio, number of pods per plant, seed yield, and 100 seed weight compared to those grown in optimal soil moisture conditions. …”
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HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context by Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado

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