Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology by Alexandra Chera, Mircea Stancu-Cretu, Nicolae Radu Zabet, Octavian Bucur

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Peripheral DNA Methylation of Cortisol- and Serotonin-Related Genes Predicts Hippocampal Volume in a Pediatric Population by Taena Hanson, Sophia Spencer, Samantha A. Harker, Fatoumata Barry, Phoebe Burton, Jennifer Beauchemin, Sarah E. Mennenga, B. Blair Braden, Viren D'Sa, Daphne Koinis-Mitchell, Sean C.L. Deoni, Candace R. Lewis

Subjects: “…DNA methylation…”
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<i>CYP24A1</i> DNA Methylation in Colorectal Cancer as Potential Prognostic and Predictive Markers by Ru-Hua Zhou, Lei Li, Qing-Jian Ou, Yi-Fan Wang, Yu-Jing Fang, Cai-Xia Zhang

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Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis by Bing Xia, Yan-lin Lu, Jin Peng, Jing-wei Liang, Fang-qin Li, Jiu-yang Ding, Chang-wu Wan, Cui-yun Le, Jia-lin Dai, Jie-Wang, Bing Guo, Jiang Huang

“…Abstract DNA methylation modifications are an important mechanism affecting the process of atherosclerosis (AS). …”
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Evaluation of the deleted in malignant brain tumor 1 protein expression and DNA methylation profile in rheumatoid arthritis patients by Khushboo Choudhury, Monika Gandhi, Uma Kumar, Sayan Chatterjee, Ram Singh Purty

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DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells by Siti Razila Abdul Razak, Yukihiro Baba, Hiromitsu Nakauchi, Makoto Otsu, Sumiko Watanabe

“…Treating fibroblasts with 5-aza-2′-deoxycytidine increased the expression of miR-142-3p significantly and reduced methylation at the CpG sites, suggesting that the expression of miR-142-3p is suppressed by DNA methylation in fibroblasts. Luciferase analysis using various lengths of the 5′ genomic region of miR142-3p indicated that CpGs in the proximal enhancer region may play roles in suppressing the expression of miR-142-3p in fibroblasts.…”
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Effect of The Duration of The Diagnosis on DNA Methylation Changes in Three Different Diabetic Genes in Type 2 Diabetes Mellitus by Harem Othman Smail

Subjects: “…DNA methylation…”
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Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model. by Yuzhu Hu, Dongmei Su, Yue Zhang, Yanjiang Fu, Sijia Li, Xiaoya Chen, Xiao Zhang, Shunfei Zheng, Xu Ma, Shanshan Hu

“…DNA methylation is known to be associated with cataracts. …”
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Intraspecific epigenomics divergence in brown bears (Ursus arctos): insights from genome-wide DNA methylation patterns by Paolo Colangelo, Paolo Colangelo, Ian Marc Bonapace, Laura Gramolini, Emanuela Solano, Emanuela Solano, Elisa Desiato, Paolo Franchini, Leonardo Gentile, Roberto Guadagnini, Oddmund Kleven, Jonas Kindberg, Jonas Kindberg, Alexander Kopatz, Paolo Ciucci

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Immunodeficiency, Centromeric Instability, and Facial Dysmorphism (ICF) Syndrome: How HSCT alters the impairment of the DNA methylation process by Wojciech Homa, Joanna Wanat, Izabela Dzikowska, Agata Siejka, Daria Stefaniak, Aleksandra Warunek, Gabriela Gronowicz, Michał Chról, Weronika Zielińska

“…Advances in molecular biology and genetics enabled insights into the DNA methylation machinery, which allowed us to gain a more precise understanding of the pathogenesis of ICF and also opened up opportunities for the development of new therapeutic options. …”
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Spatial Learning Is Associated with Antagonist Outcomes for DNA Methylation and DNA Hydroxymethylation in the Transcriptional Regulation of the Ryanodine Receptor 3 by Rodrigo F. Torres, Bredford Kerr

“…Interestingly, stimuli that increase neuronal activity upregulate the transcriptional activity of Ryr3 and augment DNA methylation in its proximal promoter. However, if these observations are valid for complex behavioral tasks such as learning and memory remains being evaluated. …”
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Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication by Dohoon Lee, Bonil Koo, Seokhyeon Kim, Jamin Byun, Junshik Hong, Dong-Yeop Shin, Choong-Hyun Sun, Jaesung Kim, Ji-Joon Song, Siddhartha Jaiswal, Sung-Soo Yoon, Sun Kim, Youngil Koh

“…We present that methylomes of DNMT3A INS AMLs are considerably different from those of DNMT3A R882 AMLs in that they exhibit increased intratumor DNA methylation heterogeneity in bivalent chromatin domains. …”
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Restriction Enzyme Analysis of DNA Methylation in “Condensed” Chromatin of Ha-Ras-Transformed NIH 3T3 Cells by Maria Luiza S. Mello, Ann F. Chambers, Benedicto C. Vidal, Wolfgang Planding, Ulrich Schenck

“…The structural basis for this oncogene‐mediated alteration in nuclear organization is unknown. Since DNA methylation is likely to be involved in regulating the nucleosomal level of DNA packaging, we studied the role of DNA methylation in higher‐order chromatin organization induced by Ha‐ras. …”
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Unraveling the causal impact of smoking and its DNA methylation signatures on cardiovascular disease: Mendelian randomization and colocalization analysis by Si Cao, Youjie Zeng, Ke Pang, Minghua Chen, Ren Guo, Nayiyuan Wu, Chao Fang, Huiyin Deng, Xiaoyi Zhang, Xiaohui Xie, Wen Ouyang, Heng Yang

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Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium by Irene F. Marques, Carola Domènech-Panicello, Madelon L. Geurtsen, Thanh T. Hoang, Rebecca Richmond, Kristen Polinski, Lea Sirignano, Christian M. Page, Anne-Claire Binter, Todd Everson, Amber Burt, Michael Deuschle, Maria Gilles, Fabian Streit, Sunni L. Mumford, Per Magnus, Irwin K. M. Reiss, Marijn J. Vermeulen, Stephanie H. Witt, Inês Chaves, Edwina Yeung, Stephanie J. London, Mònica Guxens, Janine F. Felix

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Epigenome-wide DNA methylation profiling in septic and non-septic patients with similar infections: potential use as sepsis biomarkers by Ian López-Cruz, Ian López-Cruz, José Luis García-Giménez, José Luis García-Giménez, José Luis García-Giménez, Manuel Madrazo, Manuel Madrazo, Judit García-Guallarte, Laura Piles, Federico V. Pallardó, Federico V. Pallardó, Federico V. Pallardó, Arturo Artero, Arturo Artero

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Combining Serum DNA Methylation Biomarkers and Protein Tumor Markers Improved Clinical Sensitivity for Early Detection of Colorectal Cancer by Guoying Zhang, Fang He, Guodong Zhao, Zihui Huang, Xiang Li, Xia Xia, Yidi Guo, Weiping Xu, Shangmin Xiong, Yong Ma, Minxue Zheng, Wanli Liu

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Investigating DNA Methylation of Solute Carrier Genes in Colorectal Cancer: A Comprehensive Analysis Using Microarray and Bioinformatics Tools by Nur Alia Natasya Zabidi, Rashidah Baharudin, Nurul Qistina Rus Bakarurraini, Nur Alyaa Afifah Md Shahri, Francis Tieng Yew Fu, Imilia Ismail, Muhammad Redha Abdullah Zawawi, Jodi Woan-Fei Law, Learn-Han Lee, Nurul-Syakima Ab Mutalib

“…The molecular mechanisms underlying CRC, especially DNA methylation patterns in solute carrier (SLC) genes, have gained attention due to their potential role in CRC initiation and progression. …”
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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

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Combined effects of global DNA methylation, blood lead and total urinary arsenic levels on developmental delay in preschool children by Yuu-Hueih Hsu, Chih-Yin Wu, Hui-Ling Lee, Ru-Lan Hsieh, Ya-Li Huang, Horng-Sheng Shiue, Ying-Chin Lin, Mei-Chieh Chen, Yu-Mei Hsueh

“…Abstract DNA methylation is a critical step in brain development, 5-Methyl-2'-deoxycytidine (5mdC) is one of the global DNA methylation markers. …”
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