Computational Insights in DNA Methylation: Catalytic and Mechanistic Elucidations for Forming 3-Methyl Cytosine by Mansour H. Almatarneh, Ghada G. Kayed, Mohammednoor Altarawneh, Yuming Zhao, Amita Verma

Get full text

Pre-operative DNA methylation marks as predictors of weight loss outcomes after sleeve gastrectomy by Guillermo Paz-López, Teresa M. Linares-Pineda, Andrés González-Jiménez, Raquel Sancho-Marín, Luis Ocaña-Wilhelmi, Francisco J. Tinahones, Sonsoles Morcillo, Carolina Gutiérrez-Repiso

Subjects: “…DNA methylation…”
Get full text

Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa by Tandi E. Matsha, Carmen Pheiffer, Stephen E. Humphries, Junaid Gamieldien, Rajiv T. Erasmus, Andre P. Kengne

“…To conduct a genome-wide DNA methylation in individuals with type 2 diabetes, individuals with prediabetes, and control mixed ancestry individuals from South Africa. …”
Get full text

DNA Methylation May be Involved in the Analgesic Effect of Hyperbaric Oxygen via Regulating FUNDC1 by Kun Liu, Hao Wu, Rui Gao, Guang Han

“…Our findings suggest that DNA methylation is involved in the analgesic effect of HBO via the regulation of FUNDC1.…”
Get full text

DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals by Je-Keun Rhee, Jin-Hee Lee, Hae Kyung Yang, Tae-Min Kim, Kun-Ho Yoon

Subjects: “…DNA methylation…”
Get full text

A DNA-Methylated Sight on Autoimmune Inflammation Network across RA, pSS, and SLE by Xingqiang Wang, Dongyun Lei, Jie Ding, Shuang Liu, Li Tao, Fan Zhang, Jiangyun Peng, Jian Xu

“…In this study, we integrated 5 Cytokine-Chips from genome-wide DNA methylation datasets of the 3 kind of AIDs, delta-beta value was calculated for intergroup difference, and comprehensive bioinformatics analyses of cytokine genes with aberrant methylations were performed. 125 shared differential methylation variabilities (DMVs) were identified. …”
Get full text

A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits. by Dennis Khodasevich, Nina Holland, Lars van der Laan, Andres Cardenas

“…<h4>Background</h4>DNA methylation (DNAm) provides a window to characterize the impacts of environmental exposures and the biological aging process. …”
Get full text

Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID by Andrea Polli, Lode Godderis, Dries S. Martens, Madhura Shekhar Patil, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Emma Richter, Lara Fanning, Olivia Vandekerckhove, Eveline Claeys, Wim Janssens, Natalie Lorent

“…We performed a comprehensive clinical assessment (including questionnaires and the 6-min walking test) and biological measures (global DNA methylation, telomere length, mitochondrial DNA copy number, inflammatory cytokines, and serological markers such as C-reactive protein, D-dimer, troponin T). …”
Get full text

Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis by Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

“…Thus, Cdx2’s differential CpG motif preferences enable it to navigate distinct DNA methylation profiles, activating genes specific to appropriate developmental stages.…”
Get full text

Evaluation of global DNA methylation, homocysteine and vitamin B12 levels among patients with celiac disease by Farah Tareq Yaseen, Rakad M.Kh. Al-Jumaily

Subjects: Get full text

Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus) by Neelakanteswar Aluru, Yaamini R. Venkataraman, Christopher S. Murray, Veronica DePascuale

Subjects: Get full text

Methylome analysis in long-lived men deciphers DNA methylation modifications associated with male longevity in humans by Fu-Hui Xiao, Hao-Tian Wang, Long Zhao, Tian-Rui Xia, Li-Qin Yang, Si-Yu Ma, Qing-Peng Kong

“…Summary: Men, despite having a lower likelihood of longevity compared to women, generally exhibit better health status when they achieve longevity. The role of DNA methylation in this paradox remains unclear. We performed whole-genome bisulfite sequencing on long-lived men (LLMs), long-lived women (LLWs), younger men (YMs) and younger women (YWs) to explore specific methylation characteristics in LLMs. …”
Get full text

Peripheral Blood DNA Methylation Changes in Response to <i>Centella asiatica</i> Treatment in Aged Mice by Olivia Monestime, Brett A. Davis, Cora Layman, Kandace J. Wheeler, Wyatt Hack, Jonathan A. Zweig, Amala Soumyanath, Lucia Carbone, Nora E. Gray

Subjects: Get full text

Expression of Sclerostin in Osteoporotic Fracture Patients Is Associated with DNA Methylation in the CpG Island of the SOST Gene by Yanming Cao, Bin Wang, Ding Wang, Dongxiang Zhan, Caiyuan Mai, Peng Wang, Qiushi Wei, Yamei Liu, Haibin Wang, Wei He, Liangliang Xu

“…Our study demonstrated that DNA methylation influenced the transcriptional expression of SOST gene, which probably may play an important role in the pathogenesis of primary osteoporosis.…”
Get full text

Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma by I. A. Goncharova, A. A. Zarubin, N. P. Babushkina, I. A. Koroleva, M. S. Nazarenko

Subjects: “…dna methylation…”
Get full text

A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers by Jared C. Reese, Thomas M. Zervos, Jack Rock, Abeer Tabbarah, Houtan Noushmehr, Grayson Herrgott, Ana Valeria Castro

Get full text

The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis by Shi-Hong Su, Xue-Qian Cai, Yong-Huai Li, Ai-Hui Xu, Qian Huang, Hua Niu, Qing-Hai You, Geng-Yun Sun

Subjects: Get full text

Cooperative condensation of RNA-DIRECTED DNA METHYLATION 16 splicing isoforms enhances heat tolerance in Arabidopsis by Jing Ma, Shuai Li, Tengyue Wang, Zhen Tao, Shijie Huang, Ning Lin, Yibing Zhao, Chuanhong Wang, Peijin Li

“…Here, we identify a heat-responsive gene in Arabidopsis thaliana, RNA-DIRECTED DNA METHYLATION 16 (RDM16), which encodes a pre-mRNA splicing factor. …”
Get full text

LINC02282 promotes DNA methylation of TRIM6 by recruiting DNMTs to inhibit the progression of Parkinson's disease by Lu Han, Chuansheng Zhao, Feng Jin, Rongfeng Jiang, Hao Wu

Get full text

DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches by Yi-Hsuan Tsai, Prasenjit Mitra, David Taniar, Tun-Wen Pai, Tun-Wen Pai

“…Identifying cancer biomarkers through DNA methylation analysis is an efficient approach toward the detection of aberrant changes in epigenetic regulation associated with early-stage cancer types. …”
Get full text