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221
Distinct Murine Pancreatic Transcriptomic Signatures during Chronic Pancreatitis Recovery
Published 2021-01-01“…Once during ongoing CP recovery, DEGs relevant to DNA methylation and specific signaling pathways were induced to express. …”
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222
Epigenetic Modulation on Tau Phosphorylation in Alzheimer’s Disease
Published 2019-01-01“…Epigenetic modifications, such as noncoding RNA regulation, DNA methylation, and histone modification, can directly or indirectly affect the regulation of tau phosphorylation, thereby participating in AD development and progression. …”
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223
The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape
Published 2016-01-01“…In recent years, accumulating results have shown the potential role of epigenetic mechanisms, including histone modifications, DNA methylation, and microRNAs, in the development of RA. …”
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224
Genetics and Epigenetics of Parkinson's Disease
Published 2012-01-01“…In addition, increasing evidence suggests that epigenetic mechanisms, such as DNA methylation, histone modifications, and small RNA-mediated mechanisms, could regulate the expression of PD-related genes.…”
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225
Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins
Published 2023-01-01“…Epigenetic changes are known to play an important role in the molecular genetic mechanisms of virus-induced oncogenesis. Aber rant DNA methylation is a mediator of epigenetic changes that are closely associated with the HCC pathogenesis and considered a biomarker for its early diagnosis. …”
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226
Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA
Published 2015-07-01“…Malignant cell transformation is accompanied by two processes of DNA methylation changes: promoter hypermethylation of specific genes and hypomethylation of retrotransposons. …”
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227
Atherogenic Factors and Their Epigenetic Relationships
Published 2010-01-01“…This paper summarizes some recent works on expression of histone-modifying enzymes and DNA methylation directly linked to the presence of risk factors that could lead to the development or prevention of the atherosclerotic process.…”
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228
Advances in the genetics of myasthenia gravis: insights from cutting-edge neuroscience research
Published 2025-01-01“…Moreover, the pivotal roles of epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNAs, in the pathogenesis of MG are gradually being unveiled. …”
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229
Epigenetic and epitranscriptomic regulation during oncogenic γ-herpesvirus infection
Published 2025-01-01“…In this review, we describe the intricate processes by which these viruses interact with the epigenetic machinery, leading to alterations in DNA methylation, histone modifications, and the involvement of non-coding RNAs. …”
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230
Epigenetic Dynamics: Role of Epimarks and Underlying Machinery in Plants Exposed to Abiotic Stress
Published 2014-01-01“…We present a lucid review of epigenetic machinery and epigenetic alterations involving DNA methylation, histone tail modifications, chromatin remodeling, and RNA directed epigenetic changes.…”
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231
Curcumin as a Supportive Therapy in Type 2 Diabetic Patients
Published 2024-01-01“…Also, epigenetic regulation of type 2 diabetes is discussed, especially the role of DNA methylation.…”
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232
Relationship between CTF1 gene expression and prognosis and tumor immune microenvironment in glioma
Published 2025-01-01“…CTF1 was an independent prognostic factor and negatively associated with DNA methylation. The involvement of CTF1 in m6A modifications contributed to glioma progression. …”
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233
Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC
Published 2025-01-01“…Our study encompassed a comprehensive analysis of the following aspects: differential SMAD3 expression and its association with prognosis across diverse cancer types, gene mutations, immune cell infiltration, single-cell sequencing analysis, DNA methylation patterns, and drug sensitivity profiles. …”
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234
Longitudinal genetic studies of cognitive characteristics
Published 2020-03-01“…The appropriate correction of epigenetic factors related to environmental differences in cognitive abilities requires to determine the mechanisms of chromatin modifications and variations in DNA methylation. Transposons representing stress-sensitive DNA elements appeared to mediate the environmental influence on epigenetic modifications. …”
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235
ENCODE: A Sourcebook of Epigenomes and Chromatin Language
Published 2013-03-01“…The result of this project has identified a set of new DNA regulatory elements, based on novel relationships among chromatin accessibility, histone modifications, nucleosome positioning, DNA methylation, transcription, and the occupancy of sequence-specific factors. …”
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236
Response to Hydralazine-Valproate in a Patient with Mycosis Fungoides
Published 2010-01-01“…Here we report a mycosis fungoides patient having a dramatic response to hydralazine and valproate, two repositioned drugs as HDAC and DNA methylation inhibitors, respectively.…”
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237
DNMT3a Downregulation Ttriggered Upregulation of GABAA Receptor in the mPFC Promotes Paclitaxel‐Induced Pain and Anxiety in Male Mice
Published 2025-02-01“…Abstract Chemotherapeutic agents, such as paclitaxel (PTX), induce neuroplastic changes and alter gene expression in the prefrontal cortex (PFC), which may be associated with chemotherapy‐induced pain and negative emotions. Notably, DNA methylation undergoes adaptive changes in neurological disorders, emerging as a promising target for neuromodulation. …”
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238
Gestational diabetes mellitus causes genome hyper-methylation of oocyte via increased EZH2
Published 2025-01-01“…Here, we report the influence of GDM on DNA methylation of offspring (GDF1) oocytes and the possible mechanisms. …”
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239
Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis
Published 2015-01-01“…This novel methodology, based on BEL, enables us to integrate epigenetic modifications such as DNA methylation or acetylation of histones into a specific disease network. …”
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240
Colonic Mucosal Epigenome and Microbiome Development in Children and Adolescents
Published 2016-01-01“…Intercalating age-specific DNA methylation and microbiome changes were identified, which may have significant translational relevance in the developmental origins of IBD and CRC.…”
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