Showing 21 - 40 results of 61 for search '"DHEA"', query time: 0.06s Refine Results
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    Molecular mechanism underlying cardioprotective effect of dehydroepiandrosterone on endoplasmic reticulum stress induced apoptosis in human vascular smooth muscle cells and human u... by Ye Zhu, Junxiu Wei, Xin Yang, Wei Zhu

    Published 2025-01-01
    “…DHEA was utilized to inhibit the apoptotic effects of DTT, while estrogen receptor (ER) antagonists ICI 182,780 and G15, the androgen receptor (AR) antagonist flutamide and the aromatase inhibitor letrozole were used to identify the receptors activated during DHEA treatment in HVSMCs and HUVECs. …”
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    Article
  7. 27

    Role of hypothalamic-pituitary-adrenal axis and catecholamine factors in independent and primary multiple types of tumor growth by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, Yu. A. Pogorelova, N. D. Cheryarina, L. K. Trepitaki, I. V. Neskubina, A. A. Vereskunova, I. M. Kotieva, K. A. Shumarin, A. I. Shikhlyarova, I. V. Goroshinskaya

    Published 2022-12-01
    “…An increase in serum levels of cortisol was not blocked by high levels of DHEA-S, and as a result, the cortisol/DHEA-S ratio was sharply elevated in B16 melanoma and B16+LLC combination.Conclusion. …”
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  8. 28

    Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome by Zhuo Liu, Rui-Han Wang, Ke-Hua Wang

    Published 2025-01-01
    “…Methods Dehydroepiandrosterone (DHEA)-induced PCOS rats and dihydrotestosterone (DHT)-induced PCOS cell models were established. …”
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  9. 29

    HISTOMORPHOLOGICAL ENHANCEMENT OF THE VAGINAL WALL IN DEHYDROEPIANDROSTERONE-TREATED POST-OVARIECTOMIZED WISTAR RATS by Lis Widodo Peni, Pilar Menara Falah, Yudha Nurdian

    Published 2024-07-01
    “…The exclusive source of post-menopausal sex hormones is dehydroepiandrosterone (DHEA). Purpose: Observe the impact of orally administered DHEA in the vagina of a rat (Rattus norvegicus) post- bilateral ovariectomy. …”
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  10. 30

    Dynamic decomposition and hyper-distance based many-objective evolutionary algorithm by Xujian Wang, Fenggan Zhang, Minli Yao

    Published 2024-12-01
    “…In this paper, we propose a dynamic decomposition and hyper-distance based many-objective evolutionary algorithm named DHEA. On one hand, to maximize the diversity of the population, we use dynamic decomposition to decompose the whole population into multiple clusters. …”
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  11. 31

    Correlation Analysis of Hypothalamic-Pituitary-Adrenal Axis Hormone Levels in Hair before Stroke Onset and Mood Disorders after Stroke by WANG Tiantian, JIA Yuanyuan, QI Deyi, DENG Huihua, MENG Dianhuai

    Published 2024-06-01
    “…There was no significant difference in DHEA levels between stroke patients group and healthy control group (<italic>P</italic>&gt;0.05). …”
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  12. 32

    Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome by WANG Xueling, WANG Xueling, ZHONG Peiling, ZHONG Peiling, ZHAO Zhipeng

    Published 2025-02-01
    “…In addition to the Control group, the mouse model of PCOS was established by subcutaneous injection of dehydroepiandrosterone (DHEA, 60 mg/kg) following by a high-fat diet for 21 d. …”
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  13. 33

    Sample size calculations based on day-to-day variability of stress biomarkers in persons with dementia and their family caregivers by Azita Emami, Jeehye Jun, Gabriella Engström, Lars Berglund, Töres Theorell

    Published 2024-11-01
    “…Salivary cortisol and DHEA-S samples were collected five days a week, for eight consecutive weeks. …”
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  14. 34

    Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model by Zhenye Zhu, Min Lei, Ruizhi Guo, Yining Xu, Yanqing Zhao, Chenlu Wei, Qingling Yang, Yingpu Sun

    Published 2025-01-01
    “…Graphical Abstract Ovarian NAD+ levels decreased in DHEA-induced PCOS mice, accompanied by mitochondrial dysfunction in oocytes and ovarian stromal cells, resulting in reduced oocyte quantity and quality, decreased early embryonic development potential, and increased ovarian fibrosis. …”
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  15. 35

    新疆地区男性高尿酸血症患者性腺功能减退的相关危险因素分析 by 王涵, 陈园

    Published 2023-09-01
    “…结果①与性腺功能正常组相比,性腺功能减退组的年龄、腰围(WC)、体质量指数(BMI)、空腹血糖(FPG)、空腹胰岛素(FINS)、稳态模型评估的胰岛素抵抗指数(HOMA-IR)、谷丙转氨酶(ALT)、血尿酸(SUA)、性激素结合球蛋白(SHBG)水平显著升高,而γ-谷氨酰转移酶(GGT)、25-羟基维生素D[25(OH)D]、孕酮(P)、雌二醇(E<sub>2</sub>)、脱氢表雄酮(DHEA)、血清游离三碘甲腺原氨酸(FT3)水平显著降低(<italic>P</italic> &lt; 0.05)。…”
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  16. 36

    Effects of non-pharmacological interventions on biochemical hyperandrogenism in women with polycystic ovary syndrome: a systematic review and network meta-analysis by Qi Jin, Ge Xu, Yuchen Ying, Lumin Liu, Huimin Zheng, Shifen Xu, Ping Yin, Yuelai Chen

    Published 2025-01-01
    “…No significant effects were observed on Free Androgen Index (FAI), Sex Hormone-Binding Globulin (SHBG), Dehydroepiandrosterone (DHEA), DHEA Sulfate (DHEAS), Free Testosterone (FT), or Dihydrotestosterone (DHT) levels (all p > 0.05). …”
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  17. 37

    Comparison of Plasma Neurosteroid and Prolactin Levels in Patients with Schizophrenia and Healthy Individuals by Forough Riahi, Maryam Izadi-mazidi, Ali Ghaffari, Elham Yousefi, Shahram Khademvatan

    Published 2016-01-01
    “…The present study aimed to compare plasma levels of cortisol, testosterone, dehydroepiandrosterone (DHEA), and prolactin in patients with schizophrenia and healthy individuals. …”
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  18. 38

    Autoinflammatory Reaction in Dogs Treated for Cancer via G6PD Inhibition by Jonathan W. Nyce

    Published 2017-01-01
    “…We have discovered that systemic inhibition of G6PD by high dose dehydroepiandrosterone (DHEA) causes a severe autoinflammatory response in dogs, which does not occur in mice or rats. …”
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  19. 39

    Neurosteroid Binding Sites on the GABAA Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence by Mary W. Hulin, Russell J. Amato, Johnny R. Porter, Catalin M. Filipeanu, Peter J. Winsauer

    Published 2011-01-01
    “…This paper will also present data collected by our laboratory showing that one neurosteroid in particular, dehydroepiandrosterone (DHEA), decreases ethanol intake in rats under a variety of conditions. …”
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  20. 40

    High Levels of 17β-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye by Guanglin Shen, Xiaoping Ma

    Published 2016-01-01
    “…Serum 17β-estradiol levels were significantly higher in the dry eye subjects than in the controls (P=0.03), whereas there were no significant differences in levels of testosterone, dehydroepiandrosterone sulfate (DHEA-S), and progesterone. Tear MMP-2 and MMP-9 concentrations (P<0.001), as well as the MMP-9 mRNA expression in conjunctival samples (P=0.02), were significantly higher in dry eye subjects than in controls. …”
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