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Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples
Published 2024-12-01Subjects: Get full text
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Prion meeting 2023: implications of a growing field
Published 2024-12-01“…The history of human prion diseases began with the original description, by Hans Gerhard Creutzfeldt and by Alfons Maria Jakob, of patients with a severe brain disease that included speech abnormalities, confusion, and myoclonus, in a disease that was then named Creutzfeldt Jakob disease (CJD). Later, in Papua New Guinea, a disease characterized by trembling was identified, and given the name “Kuru”. …”
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Sympathetic Prions
Published 2001-01-01“…Bovine spongiform encephalopathy, scrapie of sheep, and Creutzfeldt-Jakob disease are among the most notable transmissible spongiform encephalopathies. …”
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From Prion Diseases to Prion-Like Propagation Mechanisms of Neurodegenerative Diseases
Published 2013-01-01“…Prion diseases are fatal neurodegenerative sporadic, inherited, or acquired disorders. In humans, Creutzfeldt-Jakob disease is the most studied prion disease. …”
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Prion Diseases and the Gastrointestinal Tract
Published 2006-01-01“…These are human and animal diseases that include bovine spongiform encephalopathy, scrapie and Creutzfeldt-Jakob disease. They are uniformly fatal neurological diseases, which are characterized by ataxia and vacuolation in the central nervous system. …”
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The burden of medical contraindications to corneal donation: Time for review.
Published 2024-01-01“…In over 50 years and an estimated 2.5 million transplants, only 8 cases of rabies, 2 cases of hepatitis B and 2 cases of Creutzfeldt-Jakob disease (CJD) have been documented. Conversely, other cases of rabies, HIV, hep C, hep B and CJD have not been transmitted via keratoplasty. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications
Published 2025-01-01“…Elevated CHI3L1 levels have been observed in neurological conditions such as traumatic brain injury (TBI), Alzheimer’s disease (AD), Parkinson’s disease (PD), Amyotrophic lateral sclerosis (ALS), Creutzfeldt-Jakob disease (CJD), multiple sclerosis (MS), Neuromyelitis optica (NMO), HIV-associated dementia (HAD), Cerebral ischemic stroke (CIS), and brain tumors. …”
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