Association Between Artificial Liver Support System and Prognosis in Hepatitis B Virus-Related Acute-on-Chronic Liver Failure by Cui K, Liu CH, Teng X, Chen F, Xu Y, Zhou S, Yang Q, Du L, Ma Y, Bai L

“…Kunping Cui, Chang-Hai Liu, Xiangnan Teng, Fang Chen, Yan Xu, Shaoqun Zhou, Qi Yang, Lingyao Du, YuanJi Ma, Lang Bai Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of ChinaCorrespondence: YuanJi Ma; Lang Bai, Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Tel +86-02885422650 ; +86-18980602254, Email maxe.doc@163.com; pangbailang@163.comObjective: The artificial liver support system (ALSS) has been recruited as an available method for patients with acute-on-chronic liver failure (ACLF), but its impact on the outcome of ACLF remains controversial. This study aimed to investigate the association between ALSS treatment and short-term prognosis of hepatitis B-related ACLF (HBV-ACLF).Methods: This was a retrospective observational cohort study, and data were obtained from the Center of Infectious Diseases, West China Hospital of Sichuan University, between Mar 2015 and December 2021. …”
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Temporal trends and differences of SARS-CoV-2-specific antibody responses in symptomatic and asymptomatic subjects: a longitudinal study from Umbria in Italy by Iosief Abraha, Paolo Eusebi, Marta Micheli, Antonella Germani, Erica Pasquarelli, Sofia Pascolini, Rossana Antonietti, Sandro Argenti, Alessandra Fioravanti, Elisa Martini, Luana Aristei, Paola Mancinelli, Maria Letizia Ottaviani, Martina Roselli, Milena Barzacca, Erika Belardinelli

“…Objectives Dynamics of antibody responses following SARS-CoV-2 infection are controversial in terms of immunity and persistence. We aimed to assess longitudinally the trend of antibody serological titres, their correlation with clinical severity as well as clinical reinfection during a follow-up.Design Longitudinal cohort, 12 months follow-up study.Setting USL Umbria 2.Participants Consecutive subjects aged 15–75 who were discharged with the diagnosis of Sars-Cov-2 from the hospitals of the AUSL Umbria 2, or resulted positive to a PCR test for SARS-CoV-2 infection with or without symptoms were recruited. …”
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Improper lung volume-dose parameters are risk factors for acute fatal radiation pneumonitis among esophageal cancer patients receiving chemoradiotherapy: a case-control study by Ruinuo Jia, Liuyan Li, Xiaoyi Liu, Junqian Zhang, Shuoguo Li, Ziqi Wang, Jingxia Li, Bingyi Xu, Manxi Sheng, Lei Ni, Danni Yang, Shegan Gao, Shegan Gao, Shegan Gao

“…However, acute fatal radiation pneumonitis (AFRP) is one of the most harmful complications and it is still controversial which factors pose a greater risk.AimThis case-control study aims to investigate the relationship between AFRP and lung volume-dose parameters in patients with esophageal cancer undergoing DCRT.MethodsCases are patients who died of AFRP after DCRT, whereas controls are patients who did not develop RP. …”
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Prognosis of nodal micrometastasis in resectable pN0 non-small cell lung cancer by Sophon Siwachat, Sophon Siwachat, Sophon Siwachat, Apichat Tantraworasin, Apichat Tantraworasin, Apichat Tantraworasin, Nirush Lertprasertsuke, Somcharoen Saeteng, Somcharoen Saeteng

“…However, the benefits of NMM detection in resectable cases remain controversial due to conflicting results from retrospective studies. …”
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Clinical Outcome and Quality of Life after Modular Reverse Total Shoulder Arthroplasty in Comparison with Joint‐Preserving Locking Plate Osteosynthesis in Aged Patients: A Retrospe... by Carina Jaekel, Lisa Oezel, Franziska Leibnitz, Lena Marie Wilms, Joachim Windolf, Sebastian Viktor Gehrmann, Armin Olaf Scholz

“…While nondisplaced fractures achieve good results by conservative treatment, surgical procedures are discussed controversially. Next to open reduction and internal fixation (ORIF), the primary use of reverse shoulder arthroplasty (RSA) has become increasingly important. …”
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Effects of clear aligners treatment in growing patients: a systematic review by Vincenzo D’Antò, Vittoria De Simone, Silvia Caruso, Paolo Bucci, Rosa Valletta, Roberto Rongo, Rosaria Bucci

“…However, while dentoalveolar effects have been reported consistently, controversial findings were found regarding the changes in skeletal bases after treatment with CA. …”
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Clinical outcomes of COVID-19 in patients with liver cirrhosis - a propensity-matched analysis from a multicentric Brazilian cohort by Luanna Silva Monteiro Menezes, Pedro Ferrari Sales da Cunha, Magda Carvalho Pires, Lucas Rocha Valle, Flávia Carvalho Cardoso Costa, Maria Angélica Pires Ferreira, Milton Henriques Guimarães Júnior, Saionara Cristina Francisco, Marcelo Carneiro, Daniel Vitório Silveira, Fernando Graça Aranha, Rafael Lima Rodrigues de Carvalho, Teresa Cristina de Abreu Ferrari, Milena Soriano Marcolino

“…However, this concept is controversial in the literature. We aimed to evaluate clinical outcomes by comparing patients with cirrhosis to those without cirrhosis in a Brazilian cohort. …”
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What Is the Best Proximal Anastomosis for the Free Right Internal Thoracic Artery during Bilateral Internal Thoracic Artery Revascularization? A Prospective, Randomized Study by S. Neragi-Miandoab, R. E. Michler, F. Lalezarzadeh, R. Bello, J. J. DeRose

“…The ideal functional BITA configuration remains controversial. Methods. Patients undergoing planned BITA revascularization with greater than 75% stenosis in both the left anterior descending artery (LAD) and in a circumflex branch were prospectively randomized to one of two proximal free right internal thoracic artery (RITA) connections directly off the aorta (Ao) (n=12) or as a “t” graft off the LITA (t) (n=12). …”
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HCV Eradication with Direct-Acting Antivirals Does Not Impact HCC Progression on the Waiting List or HCC Recurrence after Liver Transplantation by Juliet A. Emamaullee, Mariusz Bral, Glenda Meeberg, Aldo J. Montano-Loza, Vincent G. Bain, Kelly Warren Burak, David Bigam, A. M. James Shapiro, Norman Kneteman

“…Treatment of patients awaiting liver transplantation (LT) has been controversial. Recent data suggests that DAA treatment may accelerate recurrent HCC. …”
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RECIST 1.1 versus mRECIST for assessment of tumour response to molecular targeted therapies and disease outcomes in patients with hepatocellular carcinoma: a systematic review and... by Yao Yang, Yuping Bai, Hongli Yu, Qiang Zhu, Xiaoyu Xie, Yuemin Feng

“…Which one is better to evaluate efficacy after molecular targeted therapies in hepatocellular carcinoma (HCC) patients is still controversial. A systemic review was performed to compare the objective response rate (ORR) and disease control rate (DCR) and a meta-analysis was conducted to compare the correlation between objective response and overall survival (OS).Design Systematic review and meta-analysis using the Grading of Recommendations Assessment, Development and Evaluation approach.Data sources EMBASE, PubMed, Web of Science and Cochrane Library were searched through 31 December 2021.Eligibility criteria We included studies assessing the efficacy of molecular targeted therapy for HCC according to both RECIST 1.1 and mRECIST.Data extraction and synthesis Two investigators extracted data independently. …”
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Relationship Between Obstructive Sleep Apnea and Enuresis in Children: Current Perspectives and Beyond by Wang Z, Zhang P, Shi R, Yang S, Liu K, Zhou Z, Li Q

“…Moreover, the benefits of surgical and non-surgical treatments for OSA on NE symptoms remain controversial. This review summarizes the relationship between NE and OSA and how to treat them, aiming to provide a reference for the clinical treatment of OSA and NE in children.Methods: All pertinent original publications to this point from PubMed database have been collected, including investigations on the connection between OSA and NE as well as studies on the mechanism and therapeutic strategy of NE in children with OSA.Results: There is a bidirectional relationship between OSA and NE in children. …”
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Analisis Framing Pemberitaan Program Kerja Makan Siang Gratis Prabowo-Gibran Dalam Media Online Liputan6.Com Dan Republika.co.id by Fadisa Rahma Devi Triana, Muhammad Thoyib Amali

“…The purpose of this research is to describe how two online media portals, Liputan6.com and Republika.co.id, frame the news regarding the budget cuts of the controversial free lunch program. This research uses Robert N. …”
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The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis by Peiye Zhu, Yunrui Jin, Jiya Sun, Xia Zhou

“…BackgroundThe effects of resveratrol supplementation on inflammation and oxidative stress in patients with type 2 diabetes mellitus (T2DM) were controversial. A meta-analysis was performed to assess the changes in levels of inflammation and oxidative stress in patients with T2DM.MethodsRelevant literatures before November 6, 2024 were screened through Web of Science,Embase,the Cochrane Library and other sources (ClinicalTrials, ProQuest Dissertations and Theses). …”
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Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study by Hayabusa Takano, Hayabusa Takano, Naoki Kanda, Naoki Kanda, Yuji Wakimoto, Hiroyuki Ohbe, Kensuke Nakamura, Kensuke Nakamura

“…The efficacy of intravenous immunoglobulin (IVIG) as adjunctive therapy on mortality remains controversial. Moreover, IVIG may favorably affect sepsis-induced immunosuppression like persistent inflammation, immunosuppression, and catabolism syndrome (PICS).MethodsThis study was a retrospective cohort study using inpatient claims database provided by Medical Data Vision, which included approximately 190,000 episodes of intensive care unit admissions in Japanese acute care hospitals between April 2008 and September 2021. …”
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Legal regime of property registration: civil-legal aspect by Serdyuk R.

“…The purpose of the work is to analyze the legal regime of property registration, to identify shortcomings, gaps and contradictory legislation, to develop a scientific approach to solving controversial issues. Methodology. The methodology includes the application of general scientific and special legal methods of scientific knowledge, in particular: dialectical, systemic analysis, induction and deduction, comparative legal, prognostic legal. …”
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Social and Humanitarian Factor in South Korea's External Relations and The Korean Question by O. S. Pugacheva

“…While developing the discourse of South Korea as a middle power, the South Korean leadership seeks to take part in creating norms and rules in different fields of global governance. Despite controversies concerning its status and policy as that of a middle power, South Korea advances through public diplomacy the discourse that constructs and enhance its middle power status and can contribute in forming the corresponding national identity. …”
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Associations between disease severity, depression, health-related quality of life, and physical activity in adults with sickle cell disease by Adekola B. Ademoyegun, Mutiu A. Adeyemo, Babatunde Y. Adewuyi, Adebukola G. Ibitoye, Olalekan I. Akerele, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Physical activity (PA) is known to reduce inflammatory activity and enhance psychosocial health in individuals with chronic illnesses; however, there exist controversies on the role of PA in disease severity (DS), depression, and health-related quality of life (HRQoL) in SCD. …”
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Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Shichun Chen, Yongxiang Xu, Weichao Han, Runkai Hu, Minyi Chen, Ruirong He, Shaobo Ding

“…However, the clinical efficacy of MSC in the treatment of DDD still lacks clinical evidence and is controversial. We conducted a meta-analysis with randomized controlled trials (RCTs) to evaluate the clinical efficacy and safety of MSC transplantation in patients with DDD. …”
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The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis by Guilin Zhang, Guixing Xu, Yao Tang, Lingxue Zhang, Xi Chen, Xingyu Liang, Ling Zhao, Dehua Li

“…Background: Postoperative pain is a significant yet inadequately managed complication following surgery, and auriculotherapy to alleviate acute postoperative pain (APP) and reduce the use of opioids remains controversial. Methods: We searched the MEDLINE, Web of Science, Embase, Cochrane Library, CINAHL Complete, and ClinicalTrials.gov from inception to January 23, 2024 for all randomized controlled trials (RCTs) of auriculotherapy in the treatment of APP. …”
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Circulating levels of adiponectin and AdipoR expression in peripheral blood mononuclear cells are associated with lower respiratory tract Infection by Qian Wang, Xuemei Wang, Danning Xu, Mengjie Jiang, Yidan Gao, Lijuan Jiang, Meilian Liu, Haoneng Tang, Lingli Tang

“…ObjectiveThe role of adiponectin (APN) in regulating inflammation is well recognized in metabolic disease, but the dysregulation of APN in lower respiratory tract infection (LRTI) remains controversial. We aimed to measure APN and its signaling receptors, adiponectin receptor (AdipoR), in peripheral blood mononuclear cells (PBMCs) from LRTI patients to explore their potential roles in the LRTI process.MethodsA total of 99 LRTI patients from the Second Xiangya Hospital of Central South University were categorized into acute (n=35) and non-acute (n=64), and non-severe (n=62) and severe (n=37) groups. …”
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