Refined Mapping of Subsurface Water Ice on Mars to Support Future Missions by G. A. Morgan, N. E. Putzig, D. M. H. Baker, A. Pathare, C. M. Dundas, M. B. Russell, M. R. Perry, M. Chojnacki, H. G. Sizemore, A. M. Bramson, E. I. Petersen, S. Nerozzi, R. H. Hoover, Z. Bain

“…The new mapping incorporates both an enhancement in our mapping of geomorphic features and surveys of thermal contraction crack polygons. Our results demonstrate the highly variable nature of the spatial distribution of the shallowest ground ice, with the most equatorward excursions occurring below 30° latitude N/S, locations thought to be out of equilibrium with the current climate.…”
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Subtle changes in Purkinje cell firing in Purkinje cell-specific Dyt1 ΔGAG knock-in mice by Hong Xing, Pallavi Girdhar, Yuning Liu, Fumiaki Yokoi, David E. Vaillancourt, Yuqing Li

“…DYT1 dystonia is an inherited early-onset generalized dystonia characterized by sustained muscle contractions causing abnormal, repetitive movements or postures. …”
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The Overaction of the Inferior Oblique Muscle and Associated Vertical Strabismus: Prevalence, Etiology and Diagnosis by Masoud Khorrami-Nejad, Huda Karim, Wisam Hatem, Mustafa Abdullah, Ali Gheibi, Mohammad Ghasemi Boromand

“…The mechanism of action of the IO muscle is complex and varies with the globe's position during contraction. Beyond horizontal and vertical movements, the IO muscle also contributes to torsional eye movements, impacting the diagnosis and treatment of vertical strabismus and cyclotropia. …”
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Which Positions Optimize Pelvic Floor Activation in Female Athletes? by Elena Sonsoles Rodríguez-López, Luz María Martín-Márquez, María Barbaño Acevedo-Gómez, África López-Illescas, María Benito-de-Pedro, Cristina Ojedo-Martín

“…The percentage of maximum voluntary contraction also differed according to each position (<i>p</i> = 0.001). …”
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Impact of Long COVID on Lung Function in Children by Zeynep Reyhan ONAY, Sinem CAN OKSAY, Deniz MAVI TORTOP, Gulay BILGIN, Yetkin AYHAN, Ferit DURANKUS, Saniye GIRIT

“…Methods: We conducted a prospective, single-center cohort study focusing on children experiencing prolonged respiratory symptoms after contracting COVID-19. Spirometry, 6- minute walk tests (6MWTs), and tests of lung volume, the diffusing capacity of the lungs for carbon monoxide (DLCO), and fractional exhaled nitric oxide (FeNO) were performed on COVID-19 survivors at least 4 weeks after infection and a group of healthy control subjects. …”
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Discrete Fractional-Order Modeling of Recurrent Childhood Diseases Using the Caputo Difference Operator by Yasir A. Madani, Zeeshan Ali, Mohammed Rabih, Amer Alsulami, Nidal H. E. Eljaneid, Khaled Aldwoah, Blgys Muflh

“…The existence theory is established using Brouwer’s fixed-point theorem and the Banach contraction principle, providing a comprehensive mathematical foundation for the model. …”
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Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes by Cherilyn Uhm, Jianlei Gu, Weina Ju, Stephanie Pizzella, Hande Oktay, Joyce Yao-Chun Peng, Sararose Guariglia, Yong Liu, Hongyu Zhao, Yong Wang, Ramkumar Menon, Nanbert Zhong

“…In contrast, sPTL was marked by increased smooth muscle contraction, vascular remodeling, and altered signaling dynamics involving fibroblasts, including TGF-β and WNT pathways. …”
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You Can’t Climb a Broken Ladder: Examining Underrepresentation of Multiply-Disadvantaged Groups in Secure and Senior Roles in UK Geochemistry by Pallavi Anand, Pieter Bots, Jessica Gagnon, Francis Appiah, Elena Maters, Shonil Bhagwat, Susan Little, Amy Riches, Ernest ChiFru, Anya Lawrence, Bryne Ngwenya

“…This UK based case study on diversity and inclusion suggests that the career paths of geochemists belonging to multiple disadvantaged groups are restricted, including overrepresentation among those on fixed-term contracts or in service roles for laboratory support. …”
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Spatiotemporal range dynamics and conservation optimization for endangered medicinal plants in the Himalaya by Fu-Lv Liu, Winnie Wanjiku Mambo, Jie Liu, Guang-Fu Zhu, Raees Khan, Abdullah, Shujaul Mulk Khan, Lu Lu

“…Our results showed that the habitat of most medicinal plants in the Himalaya have expanded their habitat range from the Last Glacial Maximum to the present, with a substantial contraction projected in both future scenarios. Six species migrated northwards towards high elevation, while four species migrated southwards. …”
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A novel cytoprotective organ perfusion platform for reconstructing homeostasis of DCD liver while alleviating IRI injury by Tingting Lan, Mingxing Yu, Tao Ming, Hong Wang, Juan Deng, Shuhan Cheng, Zhongyang Shen, Deling Kong

“…Abstract Pump is a vital component for expelling the perfusate in small animal isolated organ normothermic machine perfusion (NMP) systems whose flexible structure and rhythmic contraction play a crucial role in maintaining perfusion system homeostasis. …”
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Exploring the metabolic patterns and response mechanisms of bile acids during fasting: A study with poultry as an example by Jun Zhang, Yujie Gong, Yidan Zhu, Qingduo Zeng, Hao Zhang, Ruili Han, Yujie Guo, Donghua Li, Yadong Tian, Xiangtao Kang, Yawei Yang, Zhuanjian Li, Ruirui Jiang

“…In addition, enhanced gallbladder contraction and increased hunger were observed in laying hens during fasting. …”
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Atrial Arrhythmias in Patients with Severe COVID-19 by Kai-Yue Han, Qi Qiao, Ye-Qian Zhu, Xin-Guang Chen, Xing-Xing Kang, Gao-Feng Zhang, Xun-Chao Cai, Yong Du, Jing Jin, Ruo-Min Di, Chen-Xi Yang, Feng-Xiang Zhang, Ying-Jia Xu

“…Plasma creatine kinase isoenzyme (CKMB) levels (P=0.01) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P=0.05). Premature atrial contractions (PAC) and nonsustained atrial tachycardia (NSAT) were significantly positively correlated with plasma CKMB levels but not with high-sensitive cardiac troponin I or myoglobin levels. …”
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Commissioning health services for First Nations, regional, and remote populations: a scoping review by Henry Boer, Janya McCalman, Chris Doran, Amanda Rush, Bridgett Mitchell, Ruth Fagan, Elizabeth Whiting, Megan Kreis, Hannah Johnson, David Lyon

“…The studies reported enabling conditions for effective commissioning including operating models that were responsive to beneficiary needs, workforce and technical capability, flexibility and duration of contracts, adequate funding, and achievable health outcomes and indicators. …”
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Post-COVID-19 conditions and health effects in Africa: a scoping review by Mustapha Amoadu, Promise Kwame Salu, David N Banaaleh, Edward W Ansah, Martin S Daanko

“…In addition to its grave effects on the global systems, there is continuation or development of new symptoms among individuals who have contracted the virus, with the potential to further stress the health systems on the continent. …”
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Noninvasive release of tendons using MRI guided focused ultrasound: a hybrid therapy using long-pulse focused ultrasound followed by thermal ablation by William Chu Kwan, Imogen den Otter-Moore, Ari Partanen, Karolina Piorkowska, Unni Narayanan, Adam C. Waspe, James M. Drake

“…The standard deviation for the area of thermal injury was also smaller for the hybrid protocol, suggesting greater predictability.Conclusion This study demonstrated a hybrid MRgFUS protocol combining long-pulse FUS followed by thermal ablation to be noninferior and safer than an ablation-only protocol for extracorporeal in-vivo tendon rupture for future clinical application for noninvasive release of contracted tendon.…”
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Epidermal stem cell derived exosomes-induced dedifferentiation of myofibroblasts inhibits scarring via the miR-203a-3p/PIK3CA axis by Shixin Zhao, Haoran Kong, Dahu Qi, Yushuang Qiao, Yu Li, Zhiming Cao, Hanwen Wang, Xuefeng He, Hengdeng Liu, Hao Yang, Suyue Gao, Tao Liu, Julin Xie

“…After in vitro and in vivo treatment with EpiSC-EVs, we assessed antifibrotic effects through scratch assays, collagen contraction assays, Western blotting, and immunofluorescence. …”
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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcquire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

“…We present a turnkey iPSC-based model of the NMJ employing channelrhodopsin-2 expression within the motor neuron (MN) population driving muscle contraction in response to blue light. MNs co-cultured with engineered skeletal muscle tissues produced twitch forces of 34.7 ± 22.7 µN in response to blue light, with a response fidelity > 92 %. …”
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Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

“…Through Multivariate environmental similarity surface (MESS) and most dissimilar variable (MoD) analyses revealed that increased climate variability under high emission scenarios, especially in ssp585, led to large-scale habitat contraction due to rising temperatures and unstable precipitation patterns. …”
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Coupling analysis of multi-systems urbanization: Evidence from China by Junqiang Luo, Weijing Ma, Shuang An, Zining Zhang, Yanchuan Fu, Hejun Huang, Genying Chang

“…Low-coordination cities are mainly found in the Qinghai-Tibet Plateau, Yunnan-Guizhou Plateau, the border areas of Gansu, Shaanxi, Sichuan, Chongqing, and Hubei, the Hetao area of the Yellow River Basin, the agricultural regions of the Huanghuaihai Plain, and the southeastern hilly and mountainous areas. (2) The degree of uneven urbanization development initially expands and then contracts, with intra-regional imbalances following the pattern: “Eastern Coastal Area > Northeast Area > Middle Reaches of the Yangtze River Area > Northern Coastal Area > Middle Reaches of the Yellow River Area > Southwest Area > Southern Coastal Area > Northwest Area.” (3) The coupling and coordinated development of urbanization is closely related to the economic foundation and production energy usage. …”
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Duckweed: a starch-hyperaccumulating plant under cultivation with a combination of nutrient limitation and elevated CO2 by Ling Guo, Ling Guo, Yang Fang, Songhu Wang, Yao Xiao, Yanqiang Ding, Yanling Jin, Xueping Tian, Anping Du, Zhihua Liao, Kaize He, Shuang Chen, Yonggui Zhao, Li Tan, Zhuolin Yi, Yuqing Che, Lanchai Chen, Jinmeng Li, Leyi Zhao, Peng Zhang, Zhengbiao Gu, Fangyuan Zhang, Yan Hong, Qing Zhang, Hai Zhao

“…In this study, we integrated whole-genome sequencing, epigenomics, transcriptomics, enzyme activity, and composition variation to elucidate the mechanisms of efficient starch accumulation in duckweed in terms of starch accumulation and carbon partitioning, regulation of the expression of genes in the starch metabolic pathway, and sucrose biosynthesis and transportation.Results and discussionAlthough Landoltia punctata exhibits dramatic gene family contraction, its starch content and productivity reached 72.2% (dry basis) and 10.4 g m-2 d-1, respectively, in 10 days, equivalent to a yield of 38.0 t ha-1 y-1, under nutrient limitation treatment with elevated CO2 levels. …”
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