Evaluation of Risk Factors Causing Diagnostic Delay in Non-steroidal Anti-inflammatory Drug-exacerbated Respiratory Disease by Melek Cihanbeylerden, Hazal Kayıkçı, Çise Tüccar, Ebru Damadoğlu, Gül Karakaya, Ali Fuat Kalyoncu

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Heat therapy in rheumatic and musculoskeletal diseases – an overview of clinical and molecular effects by Philipp Klemm, Nils Schulz, Priyanka Boettger, Uwe Lange

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Nicotine Impairs the Response of Lung Epithelial Cells to IL-22 by Hannah My-Hanh Nguyen, Jaclene Amber Torres, Sudhanshu Agrawal, Anshu Agrawal

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Clinical Course, Prognosis, and Cause of Death in Primary Sjögren’s Syndrome by Ildiko Fanny Horvath, Antonia Szanto, Gabor Papp, Margit Zeher

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Acute Myeloid Leukemia with Basophilic Differentiation Transformed from Myelodysplastic Syndrome by Yasuhiro Tanaka, Atsushi Tanaka, Akiko Hashimoto, Kumiko Hayashi, Isaku Shinzato

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PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors by Francesco Dituri, Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

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Editorial - Malaria Vaccine for Children in Sudan: Commencing Midst the Gloom of War by Imad Fadl-Elmula, Rayan Khalid

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Increased IL-21 Expression Induces Granzyme B in Peripheral CD5+ B Cells as a Potential Counter-Regulatory Effect in Primary Sjögren’s Syndrome by Gábor Papp, Edit Gyimesi, Krisztina Szabó, Éva Zöld, Margit Zeher

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Effect of miR-223-3p and miR-328a-3p Knockdown on Allergic Airway Inflammation in Rat Precision-Cut Lung Slices by Joanna Nowakowska, Maria Kachel, Wojciech Langwiński, Kamil Ziarniak, Aleksandra Szczepankiewicz

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Chronic stress resulting from stressful life events and its role in the onset of primary Sjögren’s syndrome: a comparative analysis using the modified Holmes-Rahe stress scale by Marta Jaskólska, Iga Kościńska-Shukla, Dawid Jaskólski, Alessandro Viti, Marcin Ziętkiewicz, Michał Chmielewski

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Severe Combined Immunodeficiency Disorder due to a Novel Mutation in Recombination Activation Gene 2: About 2 Cases by Ibtihal Benhsaien, Fatima Ailal, Khadija Elazhary, Jalila El bakkouri, Abdallah Badou, Ahmed Aziz Bousfiha

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Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo by Jason M. Springer, Vineesh V. Raveendran, Mingcai Zhang, Ryan Funk, Donald D. Smith, Mehrdad Maz, Kottarappat N. Dileepan

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Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma by Yu Ri Kang, MD, Hyunkyoung Kim, MS, MPH, Chae Eun Lee, BS, Jae-Woo Jung, MD, PhD, Ji-Yong Moon, MD, PhD, So Young Park, MD, MS, Sae-Hoon Kim, MD, PhD, Min-Suk Yang, MD, PhD, Byung Keun Kim, MD, PhD, Jae-Woo Kwon, MD, PhD, Hye-Kyung Park, MD, PhD, Young-Hee Nam, MD, PhD, Young-Joo Cho, MD, PhD, Taehoon Lee, MD, PhD, Ian M. Adcock, MD, PhD, Pank Bhavsar, MD, PhD, Kian Fan Chung, MD, PhD, Tae-Bum Kim, MD, PhD

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Author Correction: TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease by Menghao Zhang, Na Kang, Xin Yu, Xiaoyang Zhang, Qinghui Duan, Xianqiang Ma, Qiancheng Zhao, Zhimian Wang, Xiao’ou Wang, Yeling Liu, Yuxiao Zhang, Can Zhu, Ruiyu Gao, Xin Min, Cuifeng Li, Jin Jin, Qian Cao, Rongbei Liu, Xiaoyin Bai, Hong Yang, Lidan Zhao, Jinjing Liu, Hua Chen, Yonghui Zhang, Wanli Liu, Wenjie Zheng

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T CD3+CD8+ Lymphocytes Are More Susceptible for Apoptosis in the First Trimester of Normal Human Pregnancy by Dorota Darmochwal-Kolarz, Ewelina Sobczak, Piotr Pozarowski, Bogdan Kolarz, Jacek Rolinski, Jan Oleszczuk

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Improvement of Chronic Rhinosinusitis and Reduction of the Myeloperoxidase-Antineutrophil Cytoplasmic Antibody Titer in a Patient with Eosinophilic Granulomatosis with Polyangiitis... by Shin-ya Tamechika, Shuntaro Isogai, Shinji Maeda, Taio Naniwa, Akio Niimi

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Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation by Dashan Wang, Yuan Liu, Yan Li, Yan He, Jiyun Zhang, Guixiu Shi

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Study Protocol for the Hand OsteoArthritis Self-Management and Integrated Scheme (OASIS-H) to Improve Outcomes in Patients with Hand Osteoarthritis—an Open-Label Randomized Control... by Iris Yan Ki Tang, Lai Man Tang, Brian Ho, Joyce Wong, Amanda Lau, Suet Kei Kwok, Carmen Tze Kwan Ho

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Human Mast Cells (HMC-1 5C6) Enhance Interleukin-6 Production by Quiescent and Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells by Damandeep S. Walia, Mukut Sharma, Vineesh V. Raveendran, Jianping Zhou, Ram Sharma, Daniel J. Stechschulte, Kottarappat N. Dileepan

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SOCS1 deficiency—crossroads of autoimmunity and autoinflammation—two case reports by Kajetan Trojovsky, Maximilian Seidl, Florian Babor, Stephan Ehl, Stephan Ehl, Min Ae Lee-Kirsch, Michael Friedt, Hans-Juergen Laws, Nibras Naami, Prasad Thomas Oommen, Sujal Ghosh

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