Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis by Kylie R. VanDerMolen, Martin A. Newman, Peter C. Breen, Yunjing Gao, Laura A. Huff, Robert H. Dowen

“…Here, we identify a non-canonical role for Hedgehog (Hh), a classic regulator of development, in maintaining intestinal lipid homeostasis in Caenorhabditis elegans. …”
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Dynamical constraints on pseudo-gauge transformations by Zbigniew Drogosz, Wojciech Florkowski, Mykhailo Hontarenko, Radoslaw Ryblewski

“…Classical pseudo-gauge transformations are discussed in the context of hydrodynamic models of heavy-ion collisions. …”
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The Higgs mechanism — Hasse diagrams for symplectic singularities by Antoine Bourget, Santiago Cabrera, Julius F. Grimminger, Amihay Hanany, Marcus Sperling, Anton Zajac, Zhenghao Zhong

“…While the unbroken gauge symmetry and the number of flat directions are obtainable by classical field theory analysis for Lagrangian theories, our approach allows us to characterise the geometry of the Higgs branch by a Hasse diagram with symplectic leaves and transverse slices, thus refining the analysis and extending it to non-Lagrangian theories. …”
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Mesoscale heterogeneity is a critical determinant for spiral pattern formation in developing social amoeba by Taishi Kakizuka, Hidenori Nakaoka, Yusuke Hara, Aya Ichiraku, Yoshiyuki Arai, Hiroya Itoga, Shuichi Onami, Taro Ichimura, Takeharu Nagai, Kazuki Horikawa

“…We investigated the biological importance of mesoscale heterogeneity in signal-relaying abilities (excitability) in the self-organization of spiral waves of intercellular communications by studying the self-organized pattern formation in a population of Dictyostelium discoideum cells, a classical signal-relaying system model. By utilizing pulse-count analysis to evaluate cellular excitability, we successfully visualized the development of mesoscale heterogeneity in excitability, whose spatial scale was comparably large to that of the traveling waves of intercellular communication. …”
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Cross-scale covariance for material property prediction by Benjamin A. Jasperson, Ilia Nikiforov, Amit Samanta, Fei Zhou, Ellad B. Tadmor, Vincenzo Lordi, Vasily V. Bulatov

“…The unknown accuracy of interatomic potentials (IPs) is a major source of prediction uncertainty, severely limiting the use of large-scale classical atomistic simulations in a wide range of scientific and engineering applications. …”
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Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria? by Alina Popp, Laura Kivelä, Valma Fuchs, Kalle Kurppa

“…On the other hand, widening screening and the mistaken practice of initiating a gluten-free diet before the appropriate exclusion of celiac disease increase the number of borderline seropositive cases, which may also challenge the classical histopathological diagnostics. Sophisticated diagnostic methods and a deeper understanding of the natural history of early developing celiac disease may prove useful in these circumstances.…”
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Host-Bacteria Crosstalk at the Dentogingival Junction by M. T. Pöllänen, M. A. Laine, R. Ihalin, V.-J. Uitto

“…The tissue homeostasis is turned into tissue destruction and progression of periodontitis. The classical study of Slots showed that in the bacterial plaque, the most remarkable change is the shift from gram-positive aerobic and facultatively anaerobic flora to a predominantly gram-negative and anaerobic flora. …”
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PENGARUH KEPERCAYAAN DAN KEMUDAHAN AKSES TERHADAP KEPUTUSAN PEMBELIAN GEN Z DI ACCESS BY KAI SURABAYA by Shilvia Dwi Azzahra, NGAS. Dewi, I Wayan Darsana

“…The analysis techniques used are validity test, reliability test, classical assumption test, model accuracy test, descriptive statistical test, multiple linear regression analysis test, and hypothesis testing with the help of SPSS version 22. …”
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Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis by Marlene Marte Furment, Sandra Antigua Jimenez, Sangeetha Pabolu

“…Stroke in the presence of significant involvement of vertebral arteries should raise suspicion of GCA especially if classic symptoms preceded stroke event. High clinical suspicion is required to prevent delay in diagnosis and treatment.…”
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Mibefradil and Flunarizine, Two T-Type Calcium Channel Inhibitors, Protect Mice against Lipopolysaccharide-Induced Acute Lung Injury by Limei Wan, Weibin Wu, Shunjun Jiang, Shanhe Wan, Dongmei Meng, Zhipeng Wang, Jiajie Zhang, Li Wei, Pengjiu Yu

“…In this study, the pharmacological activity of mibefradil (a classical T-type calcium channel inhibitor) was assessed in a mouse model of lipopolysaccharide- (LPS-) induced ALI. …”
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Wireless microwave-to-optical conversion via programmable metasurface without DC supply by Xin Ge Zhang, Ya Lun Sun, Bingcheng Zhu, Han Wei Tian, Bo Yuan Wang, Zaichen Zhang, Cheng-Wei Qiu, Tie Jun Cui, Wei Xiang Jiang

“…Abstract Microwave-optical interaction and its effective utilization are vital technologies at the frontier of classical and quantum sciences for communication, sensing, and imaging. …”
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Sensitivity Analysis on the Impact of Input Parameters on Seismic Hazard Results: A Case Study of Central America by Carlos Gamboa-Canté, Mario Arroyo-Solórzano, Alicia Rivas-Medina, Belén Benito

“…This study focuses on Central America, utilizing recent data from seismic, geological, and geophysical studies to improve uncertainty analyses through classic statistical methods. The results demonstrate that proper fitting of the recurrence model can stabilize acceleration variations regardless of the declustering method or <i>b-value</i> fitting method used. …”
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Design and Characterization of a Centrifugal Compressor Surge Test Rig by Kin Tien Lim, Se Young Yoon, Christopher P. Goyne, Zongli Lin, Paul E. Allaire

“…Also, they exhibit the characteristics of mild and classic surge instead of deep surge. Finally, the change in the compressor performance due to variation in the impeller tip clearance is experimentally examined, and the results support the potential of the tip clearance modulation for the control of compressor surge. …”
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Sterile osteomyelitis: a cardinal sign of autoinflammation by Tiago Borges, João Santos, Sérgio Silva

“…Additionally, other autoinflammatory disorders (AIDs) are discussed, including classical periodic fever syndromes (e.g., familial Mediterranean fever, cryopyrin- associated periodic syndromes), monogenic rare AIDs (such as hyperostosis-hyperphosphatemia syndrome, H syndrome, interferonopathies, and Singleton-Merten’s syndrome), polygenic AIDs with bone involvement (e.g., Schnitzler’s syndrome, systemic juvenile idiopathic arthritis, adult-onset Still’s disease, and calcium pyrophosphate deposition disease), and bone dysplastic syndromes. …”
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Combinatorial Robust Optimization with Decision-Dependent Information Discovery and Polyhedral Uncertainty by Omer, Jérémy, Poss, Michael, Rougier, Maxime

“…The proof of this result involves the generalization to any polyhedral uncertainty set of a classical result, showing that solving a robust combinatorial optimization problem with cost uncertainty amounts to solving several times the nominal counterpart. …”
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Quantum photonics sensing in biosystems by Ekaterina Moreva, Valeria Cimini, Ilaria Gianani, Ettore Bernardi, Paolo Traina, Ivo P. Degiovanni, Marco Barbieri

“…Quantum light, including squeezed states and N00N states, allows enhanced phase measurements by surpassing the classical shot noise limits. This advantage can be exploited in several contexts, enabling improved resolution and sensitivity, which are particularly valuable in biological contexts where traditional high-intensity illumination could damage or alter delicate samples. …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors by Ning-Bo Hao, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Zhi-Ren Zhang, Shi-Ming Yang

“…Two distinct subsets of macrophages have been proposed, including classically activated (M1) and alternatively activated (M2) macrophages. …”
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A survey on deep learning based joint source-channel coding by Tianjie MU, Xiaohui CHEN, Yiyun WANG, Lupeng MA, Dong LIU, Jing ZHOU, Wenyi ZHANG

“…Classical information theory shows that separate source-channel coding is asymptotically optimal over a point-to-point channel.As modern communication systems are becoming more sensitive to delays and bandwidth,it becomes difficult to adopt the assumption that such separate designs have unlimited computing power for encoding and decoding.Compared to joint source-channel coding,separate coding has proven to be sub-optimal when the bandwidth is limited.However,conventional joint source-channel coding schemes require complicated design.In contrast,data-driven deep learning brings new designing ideas into the paradigm.A summary of relevant research results was provided,which will help to clarify the way in which deep learning methods solve the joint source-channel coding problem and to provide an overviewof new research directions.Source compression schemes and end-to-end communication system models were firstly introduced,both based on deep learning,then two kinds of joint coding designs under different types of source,and potential problems of joint source-channel coding based on deep learning and possible future research directions were introduced.…”
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Robust Consensus Tracking Control for Multi-Unmanned-Aerial-Vehicle (UAV) System Subjected to Measurement Noise and External Disturbance by Zhiyuan Zheng, Shiji Tong, Erquan Wang, Yang Zhu, Jinliang Shao

“…In the local tracking controller design, we reveal that classic uncertainty and disturbance estimator (UDE)-based control can magnify the noise. …”
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Test Verification of Two-Stage Adaptive Delay Compensation Method for Real-Time Hybrid Simulation by Zhen Wang, Xueqi Yan, Xizhan Ning, Bin Wu

“…For this method, the main part of the system delay is coarsely compensated by the classic polynomial extrapolation (PE) method; the second stage represents a fine remedy for the remaining delay with adaptive compensation based on a discrete model of the loading system. …”
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