Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Pcp remains a leading cause of death among HIV infected patients, with mortality rates of 50% or higher for patients developing severe Pcp. …”
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MicroRNA-219 in the central nervous system: a potential theranostic approach by Nahal Shamaeizadeh, Mina Mirian

“…Finally, it reportedly has protective effects against seizures and Parkinson’s disease, as well as neoplasms, by inhibiting proliferation, suppressing invasion, and inducing cell death in tumor cells. Exploring the miR-219 molecular pathways and their therapeutic effects on central nervous system disorders and the mechanisms involved, the present review study aims to illustrate how this information may change the future of gene therapy.…”
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Activation of osteoblast ferroptosis by risperidone accelerates bone loss in mice models of schizophrenia by Hongyan Fan, Zaihong Yang, Lan Pang, Peifan Li, Changrong Duan, Guangyuan Xia, Lei Zheng

“…Abstract Background Ferroptosis is an iron-dependent regulatory cell death, which plays an essential role in bone loss. …”
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Unfavorable Tumor Responses to Immunotherapy in the Liver: Lessons Learned from Clinical and Preclinical Studies by Li-Chun Lu, Gen-Sheng Feng, Chih-Hung Hsu

“…Mechanistically, modulation of hepatic innate immune cells was associated with the improved response of anti-PD-L1 antibody in the liver. …”
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The histopathological and functional consequences of microplastic exposure by Yujeong Lee, Minkyoung Sung, Soo-Eun Sung, Joo-Hee Choi, Kyung-Ku Kang, Jae Woo Park, Ye-jin Kim, Sijoon Lee

“…Various studies confirm that microplastics stimulate cells, leading to increased reactive oxygen species production, inflammation, and cell death. …”
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A dual expression plasmid with Microcin B17 compatible with both prokaryotic and mammalian systems by Agnieszka M. Murakami, Katsuhiro Nagatomo, Hiroshi Koda, Yasutaka Niwa, Manabu Murakami

“…Proteic plasmid addiction systems, such as the control of cell death (Ccd), have been used for efficient plasmid DNA recombination. …”
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HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure by Runkuan Yang, Xiaoping Zou, Jyrki Tenhunen, Tor Inge Tønnessen

“…Acute liver failure (ALF) is the culmination of severe liver cell injury from a variety of causes. ALF occurs when the extent of hepatocyte death exceeds the hepatic regenerative capacity. …”
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Western diet promotes the progression of metabolic dysfunction‐associated steatotic liver disease in association with ferroptosis in male mice by Nicole Maddie, Nefia Chacko, David Matatov, Maria Alicia Carrillo‐Sepulveda

“…We hypothesize that ferroptosis, a recently discovered nonapoptotic iron‐dependent form of cell death, is activated during the progression of MASLD and may be a potential target for treating MASLD. …”
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Acute Liver Failure among Patients on Efavirenz-Based Antiretroviral Therapy by Innocent Lule Segamwenge, Miriam Kaunanele Bernard

“…Liver biopsies were done for all the four cases and the results showed a heavy mixed inflammatory cell infiltrate with eosinophils. For three patients withdrawal of Efavirenz from their antiretroviral regimen was sufficient to restore transaminase levels to normal and led to improvement of clinical symptoms. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Ferroptosis, a recently identified form of regulated cell death driven by iron-dependent lipid peroxidation, has emerged as a significant contributor to post-MI cardiac injury. …”
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Cutaneous Mucormycosis Co-infection in a Patient with COVID-19 by Raham Rahgoshai, Peter Goldberg, Rayhaneh Rahgoshai, Shadi Zain

“…The patient, whose history included therapy for diffuse large B-cell lymphoma, had an incidental positive screening test for COVID-19 in February 2021 after exposure to a family member who had tested positive. …”
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Functional Role of miR-499a-5p in the Development of Gastric Cancer by Cuiling Lu, Chengwang Guo, Cuihua Wu, Liping Zhang, Xiaoling Liu, Shoucun Guo

“…Overexpression of miR-499a-5p inhibits GC cell growth, migration, and invasion. Furthermore, miR499a-5p is also related to GC and 5-year survival, and is a risk factor for GC death. …”
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Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population by L. Akhmaltdinova, V. Sirota, V. Zhumaliyeva, D. Babenko, I. Kadyrova, Z. Tauesheva, D. Taizhanova, A. Ibraeva, M. Maratkyzy, A. Turmukhambetova

“…The following biomarkers were included in the study panel: stem cell factor (SCF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF2), interleukin 6 (IL6), interleukin 8 (IL8), macrophage migration inhibitory factor (MIF), soluble Fas (SFAS), soluble Fas ligand (sFASL), transforming growth factor β (TGF), tumor necrosis factor (TNF), TNF-related apoptosis-inducing ligand (TRAIL), and programmed death ligand 1 (PD-L1). …”
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The Endocannabinoid System in the Postimplantation Period: A Role during Decidualization and Placentation by B. M. Fonseca, G. Correia-da-Silva, M. Almada, M. A. Costa, N. A. Teixeira

“…Additionally, endocannabinoid’s plasmatic levels were found to fluctuate during normal gestation and to induce decidual cell death and disturb normal placental development. …”
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Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia by I. K. Hals, A. M. Rokstad, B. L. Strand, J. Oberholzer, V. Grill

“…Encapsulation provides partial immunoprotection but could possibly limit oxygen supply, a factor that may enhance hypoxia-induced beta cell death in the early posttransplantation period. …”
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Swallowing Disorders after Oral Cavity and Pharyngolaryngeal Surgery and Role of Imaging by Caterina Giannitto, Lorenzo Preda, Valeria Zurlo, Luigi Funicelli, Mohssen Ansarin, Salvatore Di Pietro, Massimo Bellomi

“…Head and neck squamous cell carcinoma is the sixth most common cancer diagnosed worldwide and the eighth most common cause of cancer death. …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…Hemorrhagic shock is a type of hypovolemic shock and a significant cause of trauma-related death worldwide. The innate immune system has been implicated as a key mediator in developing severe complications after shock. …”
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Inducing apoptosis in acute myeloid leukemia; mechanisms and limitations by Zahra Koolivand, Farbod Bahreini, Elham Rayzan, Nima Rezaei

“…This unfortunate phenomenon is practically elevated because of apoptosis inhibition in tumor cells.Two general apoptotic pathways are the Bcl-2 regulated pathway (the intrinsic pathway) and the death receptor pathway. …”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…Abstract Alzheimer’s disease (AD) is characterized by oxidative stress-mediated memory dysfunction and neuronal cell death. This study investigated the effects of an ethanol extract from Bauhinia coccinea (EEBC) on memory impairment and neuronal damage in a memory deficit mouse model. …”
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Geroprotection from ergothioneine treatment in Drosophila melanogaster by improving intestinal barrier and activation of intestinal autophagy by Hongyu Pan, Qianwang Zheng, Yuan Zou, Guozhao Luo, Mingzhen Tu, Na Wang, Jingru Zhong, Liqiong Guo, Junfang Lin

“…And ergothioneine attenuated age-related gut injuries, including decreasing reactive oxygen species levels in intestinal enterocytes, reduction of intestinal cells death, and preservation of gut integrity in aging flies. …”
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