Cardiovascular Effects Mediated by HMMR and CD44 by Kinga Jaskuła, Mariusz Sacharczuk, Zbigniew Gaciong, Dominik S. Skiba

“…Cardiovascular disease (CVD) is the leading cause of death worldwide. The most dangerous life-threatening symptoms of CVD are myocardial infarction and stroke. …”
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Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease by Sorabh Sharma, Rajeev Taliyan

“…Although the exact underlying mechanisms leading to neural cell death in this disease remains unknown, the genetic causes are often established. …”
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Ferroptosis: A New Pathway in the Interaction between Gut Microbiota and Multiple Sclerosis by Junjie Jian, Jun Wei

“…Recent advancements highlight a novel interaction between iron-dependent cell death, known as ferroptosis, and gut microbiota, which may significantly influences the pathophysiology of MS. …”
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Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities by Jiarui Zhang, Jinan Zhang, Chen Yang

“…Autophagy plays a crucial role in the development of diseases, particularly human cancers, with actions that can either promote survival or induce cell death. However, brain tumors contribute to high levels of both mortality and morbidity globally, with resistance to treatments being acquired due to genetic mutations and dysregulation of molecular mechanisms, among other factors. …”
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Spindle Bursts in Neonatal Rat Cerebral Cortex by Jenq-Wei Yang, Vicente Reyes-Puerta, Werner Kilb, Heiko J. Luhmann

“…Disturbances in spindle burst activity during corticogenesis may contribute to disorders in cortical architecture and in the activity-dependent control of programmed cell death. In this review we discuss (i) the functional properties of spindle bursts, (ii) the mechanisms underlying their generation, (iii) the synchronous patterns and cortical networks associated with spindle bursts, and (iv) the physiological and pathophysiological role of spindle bursts during early cortical development.…”
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Size, shape, and dose — three crucial determinants for applying nanoparticles in sustainable plant biology by Anindita Dey, Papiya Nandy

“…In contrast, negative effects include germination retardation, growth inhibition, cell impairment, deterioration, and eventually death. …”
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Melittin: A Natural Component of Honeybee Venom as a Potential Anti-Cancer Therapy by Niamh Donnellan, Anne M Friel

“…Cancer is a major cause of death worldwide and while chemotherapy is the main approach there are many negative associations in current treatment procedures. …”
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Complement Activation and Inhibition in Wound Healing by Gwendolyn Cazander, Gerrolt N. Jukema, Peter H. Nibbering

“…Complement activation is needed to restore tissue injury; however, inappropriate activation of complement, as seen in chronic wounds can cause cell death and enhance inflammation, thus contributing to further injury and impaired wound healing. …”
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Growth and Decay of a Planktonic Microbial Culture by Alberto Schiraldi

“…The intermediate phase between growth and decay is a time span during which growth and death counterbalance each other and age differences within the virtual cell population tend to level off. …”
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Neuroprotective effects of baicalin and baicalein on the central nervous system and the underlying mechanisms by Lujia Si, Yupu An, Jiahang Zhou, Yu Lai

“…Multiple studies have indicated that these substances effectively reduce the severity of illnesses such as depression, stroke, and degenerative disorders of the central nervous system by exerting antioxidant and anti-inflammatory effects, regulating programmed cell death, and reducing mitochondrial malfunction. …”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…Cancer is one of the leading causes of death worldwide. First-line treatments usually include surgery, radiotherapy, and/or systemic therapy. …”
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Histological Findings of ETosis in Hermansky-Pudlak Syndrome with Pulmonary Fibrosis: A Follow-Up Case Report by Sergio Michael Navarro, Aneel Ashrani, Myung Soo Park, Dong Chen

“…We present a case of HPS-PF that exhibited histological evidence of extracellular traps (ETs) ensnaring macrophages, leading to cell death in a process known as ETosis. To our knowledge, ETosis has not been previously reported in the HPS-PF population and may represent a mechanism by which pulmonary fibrosis develops in these patients. …”

Alpha-Hemoglobin-Stabilizing Protein: An Erythroid Molecular Chaperone by Maria Emília Favero, Fernando Ferreira Costa

“…Evidence strongly suggests that AHSP participates in hemoglobin synthesis and may act to neutralize the cytotoxic effects of excess free alpha-globin subunits that accumulate both in normal and beta-thalassemic erythroid precursor cells. As such, AHSP seems to be essential for normal erythropoiesis, and impaired upregulation of AHSP may lead to premature erythroid cell death, resulting in ineffective erythropoiesis. …”
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Preparation and Synergistic Anti-Tumor Effect of Iridium Oxide Nanocomposites under Microscope by Xudong He, Feng Xiang, Zhangyi Xu

“…At the same time, IrOx, as a sound-sensitive agent, can produce ROS under US irradiation, amplify intracellular oxidative stress, accelerate tumor cell death, and finally achieve the effect of SDT chemotherapy synergistic therapy. …”
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Purification, Characterization and Antibacterial Mechanism of Plantaricin 2-1 by Mengyang LI, Xiaoxue CHE, Qingshen SUN

“…Additionally, plantaricin P2-1 could cause the death of indicator strains by destroying cell integrity, breaking down cytoderm and cytomembrane, as indicated by leakage of AKP, ATP and LDH. …”
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Clinical characteristics and mortality risk factors among trauma patients by age groups at a single center in Korea over 7 years: a retrospective study by Jonghee Han, Su Young Yoon, Junepill Seok, Jin Young Lee, Jin Suk Lee, Jin Bong Ye, Younghoon Sul, Seheon Kim, Hong Rye Kim

“…In the regression analysis, 3 to 8 points on the Glasgow Coma Scale had the highest odds ratio for mortality, and red blood cell transfusion within 24 hours, intensive care unit admission, age, and Injury Severity Score were the predictors of death. …”
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Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coron... by Altekin Refik Emre, Kilinc Ali Yasar, Yanikoglu Atakan, Cicekcibasi Orhan, Kucuk Murathan

“…Background. The white blood cell count to mean platelet volume ratio (WMR) is an indicator of inflammation in patients with atherosclerotic disease. …”
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An eCIRP inhibitor attenuates fibrosis and ferroptosis in ischemia and reperfusion induced chronic kidney disease by Fangming Zhang, Zhijian Hu, Asha Jacob, Max Brenner, Ping Wang

“…Extracellular cold-inducible RNA-binding protein (eCIRP) is a stress response protein involved in acute inflammation, tissue injury and regulated cell death. However, the role of eCIRP in chronic inflammation and tissue injury has not been elucidated. …”
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Correlation between hemoglobin, albumin, lymphocyte, and platelet score and short-term mortality in critically ill patients by Chong Zhang, Wenjin Peng, Meng Ning, Weiru Liang, Bin Su, Tingting Guo, Kun Hu, Wei Su, Yi Chen, Yingwu Liu

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Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis by Yewei Jia, Rui Li, Yixuan Li, Katerina Kachler, Xianyi Meng, Andreas Gießl, Yi Qin, Fulin Zhang, Ning Liu, Darja Andreev, Georg Schett, Aline Bozec

“…Abstract Osteocytes are the main cells in mineralized bone tissue. Elevated osteocyte apoptosis has been observed in lytic bone lesions of patients with multiple myeloma. …”
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