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1161
Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo
Published 2022-01-01“…The definitive mechanisms of CI-AKI include contrast medium (CM) nephrotoxicity and CM disturbances in renal blood flow, but how the immune system responds to CM has rarely been mentioned in previous studies, and different cell death pathways have not been clearly distinguished. …”
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1162
Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer
Published 2025-01-01“…Abstract Background Cuproptosis is a novel form of cell death, acting on the tricarboxylic acid cycle in mitochondrial respiration and mediated by protein lipoylation. …”
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1163
Differential Effects of Alpha-Particle Radiation and X-Irradiation on Genes Associated with Apoptosis
Published 2011-01-01“…Four days postexposure, cell death was measured by flow cytometry and 84 genes related to apoptosis were analyzed using real-time PCR. …”
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1164
Modeling and simulation for toxicity assessment
Published 2017-05-01“…The effect of various toxicants on growth/death and morphology of human cells is investigated using the xCELLigence Real-Time Cell Analysis High Troughput in vitro assay. …”
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1165
Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity
Published 2024-11-01“…Emc, which prevents proneural bHLH transcription factors from specifying neural cell fate, also prevents homodimerization of another bHLH protein, Daughterless (Da), and thereby maintains expression of the Death-Associated Inhibitor of Apoptosis (diap1) gene. …”
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1166
Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study
Published 2025-02-01“…The cytomorphological changes associated with the chloroform extract and AO/EB dual staining indicated apoptotic cell death. An analysis of ADME properties of compounds obtained in GC-MS analysis of the chloroform extract showed that compounds such as Cyclododecanol, Sulfurous acid hexyl octyl ester, 2,4-Ditert-Butylphenol and 1,2-benzenedicarboxylic acid had favourable physicochemical and drug-likeness characteristics. …”
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1167
Mitochondrial Dysfunction in Parkinson's Disease
Published 2011-01-01“…This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area.…”
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1168
Consensus Clustering and Survival-Related Genes of Cuproptosis in Cutaneous Melanoma
Published 2023-01-01“…As a highly malignant tumor, the morbidity and mortality of cutaneous melanoma (CM) are increasing year by year. A novel type of cell death connected to mitochondrial metabolism is called cuproptosis. …”
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1169
A Literature Review and Case Report of Metastatic Pure Choriocarcinoma
Published 2015-01-01“…Testicular choriocarcinoma is one of the rarest variants of testicular germ cell tumours, accounting for less than 1% of testicular germ cell tumours and only about 0.19% of all testicular tumours. …”
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1170
Heat Shock Protein 70 Neutralizes Apoptosis-Inducing Factor
Published 2001-01-01“…Programmed cell death (apoptosis) is the physiological process responsible for the demise of superfluous, aged, damaged, mutated, and ectopic cells. …”
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1171
Targeting the initiator to activate both ferroptosis and cuproptosis for breast cancer treatment: progress and possibility for clinical application
Published 2025-01-01“…The accumulation of iron and copper ions triggers distinct cell death pathways, known as ferroptosis and cuproptosis, respectively. …”
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1172
Evaluation of extracts from Phyllostachys makinoi for their antibacterial and accelerated wound healing potential
Published 2025-01-01“…The extracts disrupted the cell membranes, causing electrolyte, protein, and nucleic acid leakage, leading to cell death. …”
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1173
Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer
Published 2025-02-01“…Abstract The development of metastasis is a leading cause of cancer-related death that involves specific changes in the plasma membrane (PM) and nucleus of cancer cells. …”
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1174
Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit...
Published 2019-01-01“…Recent emergence of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of cancers and produced prolonged response by boosting the immune system against tumor cells. The primary target antigens are cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), a downregulator of T-cell activation, and programmed cell death-1 receptor (PD-1), a regulator of T-cell proliferation. …”
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1175
The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review
Published 2010-01-01“…This involves the recognition and clearance of “not self ” pathogens and “altered self ” apoptotic cells. Phagocytic receptors (CD14, CD36, TLR–4) clear “not self” pathogens; neurons and glia express “death signals” to initiate apoptosis in T cells.The complement opsonins C1q, C3, and iC3b facilitate the clearance of apoptotic cells by interacting with CR3 and CR4 receptors. …”
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1176
Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies
Published 2025-12-01“…Furthermore, state of the art research increasingly implicates neuronal dysfunction and possibly even irreversible neuronal cell death. Cell-type specific investigation in animal models highlights the need for critical revision of the contribution of astrocytes and microglia to well-established and novel cellular and molecular alterations in hepatic encephalopathy. …”
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1177
Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy
Published 2012-01-01“…Other studies seek to pharmacologically aggravate chronic ER stress in cancer cells in order to enhance apoptosis and achieve tumor cell death. …”
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1178
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Abstract Background Death-Associated Protein Kinase 1 (DAPK1) family members are calcium/calmodulin-regulated serine/threonine kinases implicated in cell death, normal development, and human diseases. …”
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1179
Inside the mucosal immune system.
Published 2012-01-01“…This article reveals a previously unknown pathway in which several cell types and their secreted mediators work in unison to prevent epithelial cell death in the mouse small intestine. …”
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1180
Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues
Published 2025-01-01“…Abstract Cell viability assays are an integral component of toxicology and high-throughput drug screening studies; however, many assays rely on a single biomarker of cell death which provides an incomplete assessment of cell viability. …”
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