Disturbances in the Mechanism of Apoptosis as One of the Causes of the Development of Cancer Diseases by Paweł Rusin, Karolina Jabłońska

“…This mechanism of programmed cell death is designed to protect the body against uncontrolled proliferation of cells with impaired functions. …”
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Panoptosis – new frontier in research in head neck cancer by Shrikant B. Mali

“…PANoptosis, a non-apoptotic cell death mechanism, has been identified as a potential solution. …”
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The DNA Replication Stress Hypothesis of Alzheimer’s Disease by Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov

“…Chromosome reduplication without proper cell cycle completion and mitotic division probably causes neuronal cell dysfunction and death. …”
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Yeast as a Tool to Study Signaling Pathways in Mitochondrial Stress Response and Cytoprotection by Maša Ždralević, Nicoletta Guaragnella, Lucia Antonacci, Ersilia Marra, Sergio Giannattasio

“…Mitochondria, in addition to supplying cellular energy, are involved in a range of processes deciding about cellular life or death. The crucial role of mitochondria in cell death is well recognized. …”
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Ferroptosis plays a role in osteoarthritis by Ruba Altahla, Jamal Alshorman, Xu Tao

“…In recent years, ferroptosis has been identified as a novel type of regulated cell death. As a cell death process, it differs from other processes like necrosis and apoptosis in the expression of morphology, biochemistry, and genetics. …”
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The Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic Fibroblasts by Ajith Vengellur, Elizabeth Grier, John J. LaPres

“…Cadmium treatment did not affect HIF1-mediated transcription but led to caspase activation and apoptotic cell death in wild-type and HIF1α −/− cells. Cadmium-induced cell death, however, was significantly higher in HIF1α −/− cells as compared to their wild-type counterparts. …”
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Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia by Renshi Kawakatsu, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida

“…Results: Venetoclax and VPA individually had only mild effects on AML cell proliferation. However, their combination significantly inhibited cell growth and triggered pronounced cell death. …”
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Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…CD95 is one of the best studied members of the death receptor family. Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC). …”
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Ferroptosis and pyroptosis are connected through autophagy: a new perspective of overcoming drug resistance by Peng Zhao, Shuangshuang Yin, Yuling Qiu, Changgang Sun, Haiyang Yu

“…Therefore, ferroptosis and pyroptosis have crosstalk via autophagy, potentially leading to a switch in cell death types under certain conditions. As two forms of inflammatory programmed cell death, ferroptosis and pyroptosis have different effects on inflammation, and the cGAS-STING signaling pathway is also involved. …”
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3-Epi-betulinic acid 3-O-β-D-glucopyranoside (eBAG) induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma by Mengjie Liu, Xuqiang Liu, Kaiyue He, Yongping Jian, Yujia Li, Jinrong Guo, Jingyu Yang, Zhixiang Xu, Wenyi Kang

“…Herein, we report that eBAG exerted an inhibitory activity against hepatocellular carcinoma and esophageal cancer cells. EBAG induced non-apoptotic cell death in hepatocellular carcinoma cells. …”
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Interleukin-1 Modulation of Human Placental Trophoblast Proliferation

“…These findings demonstrated that IL-1 regulates human trophoblast growth by induction of cell cycle delay and cell death.</p>…”
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Targeting the Mitotic Catastrophe Signaling Pathway in Cancer by Margaret M. Mc Gee

“…Mitotic catastrophe, as defined in 2012 by the International Nomenclature Committee on Cell Death, is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and responds by driving a cell to an irreversible antiproliferative fate of death or senescence. …”
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Downregulated Copper Homeostasis-Related Gene FOXO1 as a Novel Indicator for the Prognosis and Immune Response of Breast Cancer by Rong Zeng, Bi Peng, Emin Peng

“…Moreover, FOXO1 expression was positively associated with multiple immune checkpoints, such as sialic acid-binding immunoglobulin-like lectin 15 (SIGLEC15), indoleamine 2,3-dioxygenase 1 (IDO1), programmed cell death 1 ligand 1 (PD-L1/CD274), hepatitis A virus cellular receptor 2 (HAVCR2), programmed cell death 1 (PDCD1), cytotoxic T lymphocyte antigen 4 (CTLA4), and programmed cell death 1 ligand 2 (PDCD1LG2). …”
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Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer by Jenny Ling-Yu Chen, Chun-Kai Pan, Li-Cheng Lin, Yu-Sen Huang, Tsung-Hsuan Huang, Shu-Jyuan Yang, Sung-Hsin Kuo, Yu-Li Lin

“…ATR inhibitor pretreatment decreased cell survival after irradiation by inhibiting DNA double-strand break repair, inducing mitotic cell death, and altering cell cycle progression. …”
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Divergent paths of mammary gland involution: unveiling the cellular dynamics in abruptly and gradually involuted mouse models by Sarmila Majumder, Sanjay Mishra, Neelam Shinde, Maria C. Cuitino, Morgan Bauer, Dinesh Ahirwar, Mustafa M. Basree, Vijaya Bharti, Kate Ormiston, Resham Mawalkar, Sara Alsammerai, Gautam Sarathy, Anna E. Vilgelm, Xiaoli Zhang, Ramesh K. Ganju, Bhuvaneswari Ramaswamy

“…GI elicits a more controlled immune response and extended cell death. At the peak of cell death, AI glands harbored more immunosuppressive myeloid-derived suppressor cells (MDSCs) and CD206 + M2-like macrophages, known to promote oncogenic events, compared to GI glands. …”
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NETosis Secondary to the Use of Levamisole-Adulterated Cocaine: A Likely Underlying Mechanism of Vasculopathy by Manuela Osorio, Isabel Velásquez, Ruben Vargas, Adriana Vanegas-García, Mauricio Rojas, Gloria Vásquez, Carlos Muñoz-Vahos

“…Cocaine, levamisole, and a cocaine-levamisole mixture induced neutrophil cell death. DNA/MPO extrusion and cell morphology patterns were consistent with NETosis. …”
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Liquiritin from Radix Glycyrrhizae Protects Cardiac Mitochondria from Hypoxia/Reoxygenation Damage by Vu Thi Thu, Ngo Thi Hai Yen, Nguyen Thi Ha Ly

“…Particularly, 60 μM of LIQ posthypoxic treatment markedly reduced cell death in HR-subjected H9C2 cell groups (p<0.05). …”
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Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury by Jessica M. Herrera, Yun Weng, Tyler J. Lieberthal, Marcus Paoletti, Tammy T. Chang

“…RNA-seq analysis showed upregulation of cell death, inflammatory, and profibrotic pathways in DDC-injured DKO liver as compared to DDC-injured WT liver. …”
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The Aging GABAergic System and Its Nutritional Support by Demetra J. Mills

“…The calcium channel dysfunction associated with hormone loss further leads to an excitatory cell state, which can ultimately lead to cell death. …”
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Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice by Sonja Mendritzki, Saskia Schmidt, Teresa Sczepan, Xin-Ran Zhu, Daniel Segelcke, Hermann Lübbert

“…In addition, these mice exhibit astrocytic cell death in the spinal cord, accompanied by extensive gliosis and microglial activation. …”
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