Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche by Alejandro Luarte, Luis Federico Bátiz, Ursula Wyneken, Carlos Lafourcade

“…Neurodegenerative disorders are one of the leading causes of death and disability and one of the biggest burdens on health care systems. …”
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Cytotoxic Effect of the Genus Sinularia Extracts on Human SCC25 and HaCaT Cells by Guey-Horng Wang, Tzung-Han Chou, Rong-Jyh Lin, Jyh-Horng Sheu, Shih-Hao Wang, Chia-Hua Liang

“…Flow cytometry shows that extracts sensitized the cells in the G0/G1 and G2/M phases with a concomitant significantly increased sub-G1 fraction, suggesting cell death by apoptosis. …”
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Thy1-YFP: an effective tool for single cell tracing from neuronal progenitors to mature functionally active neurons by Ante Plećaš, Katarina Kapuralin, Leonarda Grandverger, Dinko Mitrečić, Ivan Alić

“…Cell Death Discovery…”
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ERG mediates the differentiation of hepatic progenitor cells towards immunosuppressive PDGFRα+ cancer-associated fibroblasts during hepatocarcinogenesis by Haoran Bai, Xinyu Zhu, Lu Gao, Shiyao Feng, Hegen Li, Xiaoqiang Gu, Jiahua Xu, Chen Zong, Xiaojuan Hou, Xue Yang, Jinghua Jiang, Qiudong Zhao, Lixin Wei, Li Zhang, Zhipeng Han, Wenting Liu, Jianxin Qian

“…Cell Death and Disease…”
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Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer by Yen-Han Tseng, Trieu Thi My Tran, Jinghua Tsai Chang, Yu-Tang Huang, Anh Thuc Nguyen, Ian Yi‑Feng Chang, Yi-Tung Chen, Hao-Wen Hsieh, Yue-Li Juang, Peter Mu-Hsin Chang, Tzu-Yi Huang, Ying-Chih Chang, Yuh-Min Chen, Hsuan Liu, Chi-Ying F. Huang

“…Cell Death Discovery…”
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Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells by Mabeta Peace, Pavić Kristina, Zorc Branka

“…Further, the study showed that the treatment of MCF-7 cells with 1 and 3 resulted in poly ADP ribose polymerase (PARP) cleavage as well as caspase-9 activation, indicating that they induced apoptotic cell death. …”
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Effects of Aminoglycoside Antibiotics on Human Embryonic Stem Cell Viability during Differentiation In Vitro by Divya S. Varghese, Shama Parween, Mustafa T. Ardah, Bright Starling Emerald, Suraiya A. Ansari

“…However, during directed differentiation towards neural and hepatic fate, significant cell death was noted through the activation of caspase cascade. …”
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A Rare Case of Severe Facial Disfiguration Due to Extranodal NK/T-Cell Lymphoma by Deng H, Yang Q, Shi Z

“…Histopathological analysis of the two biopsies revealed inflammatory necrotic granulation tissue.Conclusion: Nasal extranodal NK/T-cell lymphoma presenting with non-specific symptoms could easily lead to misdiagnosis. …”
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β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia by Kristoffer L. Egerod, Chunyu Jin, Pia Steen Petersen, Nils Wierup, Frank Sundler, Birgitte Holst, Thue W. Schwartz

“…Mice deficient in the zinc-sensor GPR39, which has been demonstrated to protect cells against endoplasmatic stress and cell death in vitro, display moderate glucose intolerance and impaired glucose-induced insulin secretion. …”
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Unveiling cellular changes in leukaemia cell lines after cannabidiol treatment through lipidomics by David Chamoso-Sanchez, Martina Panini, Clarissa Caroli, Matilde Marani, Lorenzo Corsi, Francisco J Rupérez, Antonia Garcia, Federica Pellati

“…The results highlight some important lipid alterations related to CBD treatment, plausibly connected with different metabolic mechanisms involved in the process of cell death by apoptosis in cancer cell lines.…”
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Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials by Alejandro Victoria-Escandell, José Santiago Ibañez-Cabellos, Sergio Bañuls-Sánchez de Cutanda, Ester Berenguer-Pascual, Jesús Beltrán-García, Eva García-López, Federico V. Pallardó, José Luis García-Giménez, Antonio Pallarés-Sabater, Ignacio Zarzosa-López, Manuel Monterde

“…This study explores the cytotoxicity and genotoxicity mediated by oxidative stress of three endodontic materials that are widely used on HDPSCs: a mineral trioxide aggregate (MTA-Angelus white), an epoxy resin sealant (AH-Plus cement), and an MTA-based cement sealer (MTA-Fillapex). Cell viability and cell death rate were assessed by flow cytometry. …”
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Nivolumab plasma concentration and clearance associated with overall survival in patients with renal cell carcinoma by Aurélien Marabelle, Laurence Albiges, Angelo Paci, Cécile Dalban, David Combarel, Sophie Broutin, Christophe Maritaz, Louis Blondel

“…Background Nivolumab is an immune checkpoint inhibitor (ICI) that selectively inhibits programmed cell death protein 1 activation, restoring antitumor immunity. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…The release of intracellular DNA into the extracellular area occurs via two pathways: cell death and active secretion by cells. The DNA, which is free in the extracellular space, is commonly known as Cell-Free DNA (cfDNA). …”
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Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

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Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice by Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson

“…Co-labeling of γH2AX with NeuN revealed neuronal specificity of DNA damage, with increased early cell death (pan-nuclear γH2AX) peaking at 1 dpi and apoptosis (cleaved Caspase-3) arising later at 3 dpi. …”
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Targets of influenza human T-cell response are mostly conserved in H5N1 by John Sidney, A-Reum Kim, Rory D. de Vries, Bjoern Peters, Philip S. Meade, Florian Krammer, Alba Grifoni, Alessandro Sette

“…Analysis of human CD4 and CD8 T-cell epitope conservation between HPAI H5N1 and seasonal IAV sequences revealed levels of identity and conservation conducive to T cell cross-reactivity, suggesting that pre-existing T cell immune memory should, to a large extent, cross-recognize avian influenza viruses. …”
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Catalysts of change: Immunotherapy's frontier in oral oncology by Shyamaladevi Babu, Madhan Krishnan

“…Immunotherapy has become a potential approach to treating cancer by using the immune system to specifically target cancer cells, in contrast to traditional therapies that directly assault tumours. …”
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Targeting ferroptosis: opportunities and challenges of mesenchymal stem cell therapy for type 1 diabetes mellitus by Le Dai, Qing Wang

“…Abstract Type 1 diabetes mellitus (T1DM) is characterized by progressive β-cell death, leading to β-cell loss and insufficient insulin secretion. …”
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Inhibition of Growth and Induction of Apoptosis in Fibrosarcoma Cell Lines by Echinophora platyloba DC: In Vitro Analysis by Fatemeh Zare Shahneh, Samira Valiyari, Abbas Azadmehr, Reza Hajiaghaee, Saeid Yaripour, Ali Bandehagh, Behzad Baradaran

“…The objective of this study was to examine the in vitro cytotoxic activity and the mechanism of cell death of crude methanolic extracts prepared from Echinophora platyloba DC, on mouse fibrosarcoma cell line (WEHI-164). …”
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GH inhibits ALV-J replication and restricts cell cycle by activating PI3K/Akt signaling pathway by Junliang Xia, Ling Lin, Rongyang Ju, Chengxun Xu, Guodong Mo, Xiquan Zhang

“…More importantly, we found that GH restricted cell proliferation and apoptosis, and inhibited the replication of ALV-J by activating the PI3K/Akt signaling pathway in DF-1 cells. …”
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