Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration by Anastasia Alexandrova, Elizaveta Kontareva, Margarita Pustovalova, Sergey Leonov, Yulia Merkher

“…Cancer-related deaths primarily occur due to metastasis, a process involving the migration and invasion of cancer cells. …”
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Identification of disulfidptosis-related subtypes in gastric cancer and GAMT is a key gene during disulfidptosis by Wenxue Wu, Guoqiang Tao, Zhiqing Chen, Qi Zhou

“…Abstract Recent studies have found that disulfidptosis occurs in cells under glucose starvation. The role of this programmed death method in gastric cancer remains to be explored. …”
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

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ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans by Han Bit Baek, Debabrata Das, Shin-Yu Chen, Hongyuan Li, Swathi Arur

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Cutaneous Squamous Cell Carcinoma with Signet-Ring Cell Component and CDX2 Expression in a Patient Treated with PD-1 Inhibitor: A Case Report of a Common Tumor with Unusual Differe... by Sherehan Zada, Jeremiah Tao, Maria Del Valle Estopinal

“…Herein, we present a case of a 56-year-old female with a cutaneous SCC that recurred after surgical excision, during treatment with cemiplimab (a programmed death receptor-1 (PD-1) inhibitor). Histologically, the recurrent SCC revealed a second component characterized by the presence of signet-ring-like cells (SRLCs). …”
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A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line by Shabnam Heydarzadeh, Ali Asghar Moshtaghie, Maryam Daneshpour, Mehdi Hedayati

“…In addition, the scratch wound healing assay was conducted for cell migration. Results: The data indicated that curcumin-induced cell death is independent of apoptosis in this type of thyroid cancer cell line. …”
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An integrated cellular and sub-cellular model of cancer chemotherapy and therapies that target cell survival by Alexis B. Cook, Daniel R. Ziazadeh, Jianfeng Lu, Trachette L. Jackson

“…Apoptosis resistance is a hallmark of human cancer, and tumor cells often become resistant due to defects in the programmed cell death machinery.Targeting key apoptosis regulators to overcome apoptotic resistance and promote rapid death of tumor cells is an exciting new strategy for cancer treatment, either alone or in combination with traditionally used anti-cancer drugs that target cell division. …”
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Renal Tubular Cells from Hibernating Squirrels are Protected against Cisplatin Induced Apoptosis by Swati Jain, Alkesh Jani

“…To determine whether XIAP and Akt1 are necessary for RTEC protection against cisplatin induced apoptotic cell death, gene expression of Akt1 or XIAP was silenced in squirrel RTECs. …”
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Adipose-Derived Mesenchymal Stem Cells Migrate and Rescue RPE in the Setting of Oxidative Stress by Aya Barzelay, Shira Weisthal Algor, Anat Niztan, Sebastian Katz, Moshe Benhamou, Itay Nakdimon, Noam Azmon, Sandy Gozlan, Daphna Mezad-Koursh, Meira Neudorfer, Michaella Goldstein, Benjamin Meilik, Anat Loewenstein, Adiel Barak

“…Oxidative stress leads to the degeneration of retinal pigment epithelial (RPE) and photoreceptor cells. We evaluated the potential of adipose-derived mesenchymal stem cells (ASCs) as a therapeutic tool by studying the migration capacity of ASCs in vitro and their protective effect against RPE cell death under oxidative stress in vitro and in vivo. …”
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Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study by Narcisse Elenga, Aurélie Adeline, John Balcaen, Tania Vaz, Mélanie Calvez, Anne Terraz, Laetitia Accrombessi, Gabriel Carles

“…Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. …”
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The impact of CD3ζ ITAM multiplicity and sequence on CAR T-cell survival and function by Shubhabrata Majumdar, Hilda Echelibe, Maria Bettini, Matthew L. Bettini

“…One such challenge is the lack of long-term persistence of CD28 based CAR T-cells in patients. Although, CD28 based CAR T-cells elicit a robust acute anti-tumor response, they are more prone to early exhaustion, terminal differentiation and cell death due to their strong signaling patterns. …”
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Development of a molecular genetics and cell biology toolbox for the filamentous fungus Diplodia sapinea. by Anne Geertje Oostlander, Laura Brodde, Miriam von Bargen, Bernard Slippers, Yvonne Becker, Ulrike Brandt, Frank Klawonn, Christiaan Grobler, Lucas Well, Jan Stenlid, Jonas Oliva, Malin Elfstrand, Andre Fleissner

“…Infections can lead to severe symptoms, such as shoot blight, canker, tree death, or blue stain in harvested wood, especially in Pinus species. …”
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Absence of Cysteine and Iron Chelation Induces Ferroptosis in Triple-Negative Breast Cancer Cells by Manvi Agarwal Neeraj, JunJeong Choi

“…Background: Ferroptosis is a recently studied form of programmed cell death characterized by lipid peroxides accumulation in the cells. …”
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Transformative advancements in immune checkpoint inhibitor therapy for Oropharyngeal Squamous Cell Carcinoma (OPSCC) by Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

“…Advancements in Immune checkpoint inhibitor (ICI) treatment have greatly changed the way oropharyngeal squamous cell carcinoma (OPSCC) is treated. This paper examines the crucial advancements and their consequences for clinical practice. …”
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Clear Cell Carcinoma of the Endometrium Causing Paraneoplastic Retinopathy: Case Report and Review of the Literature by Paulina Cybulska, Eduardo V. Navajas, Filiberto Altomare, Marcus Q. Bernardini

“…Information regarding the interval from visual symptoms to time of death is limited, but ranges from several months to several years. …”
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Yinzhihuang injection induces apoptosis and suppresses tumor growth in acute myeloid leukemia cells. by Zhe Huang, Yunfu Shen, Xianming Fan, Qulian Guo, Wenzhe Ma

“…To explore the cell cycle arrest and cell death mechanism induced by YZHI, we assessed a series of assays, including measurements of the protein expression and cellular ATP. …”
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Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis by Mengzhu Li, Mengxuan Chen, Haiyan Li, Da Gao, Lijun Zhao, Meiling Zhu

“…However, the exact pathogenesis of PD remains unclear, with ferroptosis emerging as one of the key factors driven by iron accumulation and lipid peroxidation. Glial cells, including microglia, astrocytes, and oligodendrocytes, serve as supportive cells in the central nervous system (CNS), but their abnormal activation can lead to DA neuron death and ferroptosis. …”
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Advances of Neoadjuvant Targeted Therapy in ALK-positive Non-small Cell Lung Cancer by Weizhen SUN, Yuheng ZHOU, Yaobin LIN, Shoucheng FENG, Hao LONG

“…Lung cancer remains the most frequently diagnosed cancer and the leading cause of cancer-related death worldwide, with anaplastic lymphoma kinase (ALK) fusion mutations accounting for approximately 4%-9% of cases. …”
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Amarogentin suppresses cell proliferation and EMT process through inducing ferroptosis in colorectal cancer by Chao Wang, Zihao You, Guoqing Zhou, Juanjuan Dong, Sihao Tong, Guoping Sun

“…Abstract Background Colorectal cancer (CRC) is one common tumor with the high death rate, and badly affects the normal lives of CRC patients. …”
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Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases by Anne Herrmann PhD, Arthur Taylor PhD, Patricia Murray PhD, Harish Poptani PhD, Violaine Sée PhD

“…Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common. …”
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