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361
The Desmosomal Plaque Proteins of the Plakophilin Family
Published 2010-01-01“…Mutations in the human PKP 2 gene have been linked to severe heart abnormalities that lead to arrhythmogenic right ventricular cardiomyopathy (ARVC). In the past few years it has been shown that junctional adhesion is not the only function of PKPs. …”
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362
Regulatory Role of CD4+ T Cells in Myocarditis
Published 2018-01-01“…So far, a direct pathogenic role has been described for both activated Th17 and Th1 effector CD4+ T cell subsets, though Th1 effector T cell-derived interferon-gamma was shown to limit myocarditis severity and prevent transition to inflammatory dilated cardiomyopathy. Interestingly, recent observations point out that various CD4+ T cell subsets demonstrate high plasticity in maintaining immune homeostasis and modulating disease phenotypes in myocarditis. …”
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363
The Brain-Heart Connection in Takotsubo Syndrome: The Central Nervous System, Sympathetic Nervous System, and Catecholamine Overload
Published 2020-01-01“…Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a type of acute heart failure syndrome triggered by intense psychological or physiological stress. …”
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364
Etiologi dan Patofisiologi Kardiomiopati Dilatasi
Published 2018-07-01“…Kardiomiopati dilatasi atau dilated cardiomyopathy (DCM) adalah gangguan miokard yang didefinisikan oleh dilatasi dan gangguan fungsi sistolik ventrikel kiri, atau kedua ventrikel, tanpa adanya penyakit arteri koroner, kelainan katup, atau penyakit perikard. …”
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365
Erythropoietin: from erythropoiesis to cardioprotection
Published 2010-08-01“…The identification of erythropoietin receptor in hematopoietic tissues, including the heart, as well as its marked cardioprotective effect during ischemia have led to the hypothesis that erythropoietin may be able to prevent anthracycline-induced cardiomyopathy. Addressing this hypothesis is the objective of this work.…”
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366
Anesthesia Management in Scoliosis Surgery of Patients with Friedreich’s Ataxia: A Report of Four Cases
Published 2022-12-01“…Neuromuscular blocker was used for anesthesia induction in one case, we did not use it in the other cases. Hypertrophic cardiomyopathy may accompany patients with Friedreich's ataxia. …”
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367
In Vitro Contracture Test Results and Anaesthetic Management of a Patient with Emery-Dreifuss Muscular Dystrophy for Cardiac Transplantation
Published 2012-01-01“…Emery-Dreifuss muscular dystrophy (EDMD) is a hereditary neuromuscular disorder characterized by slowly progressive muscle weakness, early contractures, and dilated cardiomyopathy. We reported an uneventful general anaesthesia using total intravenous anaesthesia (TIVA) for cardiac transplantation in a 19-year-old woman suffering from EDMD. …”
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368
Antepartum Diagnosis and Management of Lamin A/C Disease
Published 2019-01-01“…Lamin A/C cardiac disease is a genetic cardiomyopathy and arrhythmia syndrome caused by alterations in the function of the nuclear lamin A and C proteins. …”
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369
The evolving spectrum of interstitial lung disease in myositis—Management pearls
Published 2020-01-01“…Patients with IIMs also have extramuscular lesions, such as skin rash, arthritis, interstitial lung disease (ILD), and cardiomyopathy. ILD is one of the leading causes of mortality in patients with IIMs. …”
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370
Juvenile Hemochromatosis due to a Homozygous Variant in the HJV Gene
Published 2022-01-01“…Hemochromatosis type 2 or juvenile hemochromatosis has an early onset of severe iron overload resulting in organ manifestation such as liver fibrosis, cirrhosis, cardiomyopathy, arthropathy, hypogonadism, diabetes, osteopathic medicine, and thyroid abnormality, before age of 30. …”
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371
Electromagnetic Interference from Swimming Pool Generator Current Causing Inappropriate ICD Discharges
Published 2017-01-01“…A 31-year-old female with arrhythmogenic right ventricular cardiomyopathy and Medtronic dual-chamber ICD placement presented after several inappropriate ICD shocks at the public swimming pool. …”
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372
Doxorubicin-Conjugated Nanoparticles for Potential Use as Drug Delivery Systems
Published 2025-01-01“…However, it is likely to produce several side effects that include doxorubicin cardiomyopathy. Nanoparticles (NPs) can offer targeted delivery and release of the drug, potentially increasing treatment efficiency and alleviating side effects. …”
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373
Adult ADHD Medications and Their Cardiovascular Implications
Published 2016-01-01“…Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD.…”
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374
Animal Models of Diabetic Neuropathy: Progress Since 1960s
Published 2013-01-01“…Diabetic or peripheral diabetic neuropathy (PDN) is one of the major complications among some other diabetic complications such as diabetic nephropathy, diabetic retinopathy, and diabetic cardiomyopathy. The use of animal models in the research of diabetes and diabetic complications is very common when rats and mice are most commonly used for many reasons. …”
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375
Cardiac Magnetic Resonance Imaging in Diagnostics and Cardiovascular Risk Assessment
Published 2025-01-01“…Novel CMR techniques, such as T1 and T2 mapping, may be used for the longitudinal follow-up of myocardial fibrosis and myocardial edema or inflammation in different groups of patients, including patients with systemic sclerosis, myocarditis, cardiac sarcoidosis, amyloidosis, and both ischemic and non-ischemic cardiomyopathy, among others. Moreover, CMR tagging and feature tracking techniques might improve cardiovascular risk stratification in patients with different etiologies of left ventricular dysfunction. …”
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376
Advancements in Cardiac Amyloidosis Treatment
Published 2024-12-01“…Cardiac amyloidosis (CA) is a progressive condition resulting from the deposition of amyloid fibrils in the heart, which leads to severe diastolic dysfunction and restrictive cardiomyopathy. The disease has two main subtypes: light-chain and transthyretin (TTR) CA, with the latter subdivided into wild-type and hereditary forms. …”
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377
Cardiac Magnetic Resonance Imaging in Lyme Carditis—A Case Series and Review of Literature
Published 2024-12-01“…While cardiac magnetic resonance (CMR) imaging is the standard imaging modality for diagnosing various etiologies of cardiomyopathy, its application in Lyme carditis remains understudied. …”
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378
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways
Published 2010-01-01“…New functions of PPARs are reported in the arrhythmogenic right ventricular cardiomyopathy, a human genetic heart disease. It is now possible to link the genetic desmosomal abnormalitiy to the presence of fat in the right ventricle, partly due to an overexpression of PPARγ. …”
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379
Evaluation of miR-146a as a potential biomarker for diagnosis of cardiotoxicity induced by chemotherapy in patients with breast cancer
Published 2025-01-01“…Background: Cardiotoxicity from chemotherapy may result in cardiomyopathy and heart failure. Clinicians can use the evaluation of cardiotoxicity-specific biomarkers, such as microRNA, as a tool for the early detection of cardiotoxicity. …”
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380
Complete AV Block in Vaccinated COVID-19 Patient
Published 2022-01-01“…Although this patient’s etiology of his complete AV block may result from multiple factors, given the acuity in setting of concurrent COVID-19 infections, top differentials include viral myocarditis, COVID-19-induced Takotsubo cardiomyopathy complicated by a complete AV-block, or a direct conduction pathway infection. …”
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