Engineering hydrophobicity and manufacturability for optimized biparatopic antibody–drug conjugates targeting c-MET by Andreas Evers, Simon Krah, Deniz Demir, Ramona Gaa, Desislava Elter, Christian Schroeter, Stefan Zielonka, Nicolas Rasche, Julia Dotterweich, Christine Knuehl, Achim Doerner

Subjects: Get full text

Application of the Slope Coefficient of the Equivalent M–C Criterion in Layered Rock Mass Engineering by Qian Liu, Qizhi Hu, Fan Zhang, Zhigang Ding, Wencheng Bao

“…The slope coefficient ω is defined based on the insufficiency of the area equivalent method, the slope of the equivalent M–C criterion obtained from the instantaneous equivalent, and the optimal first-order approximation to reduce the error between the simulated value and the measured value of the surrounding rock and ensure the safety of the project. …”
Get full text

A universal method for the purification of C2H2 zinc finger arrays. by Jingchang Liang, Maia Azubel, Guanqiao Wang, Yan Nie, Roger D Kornberg, Andrew J Beel, Pierre-Jean Mattei

“…Here we describe a simple method, involving two chromatographic steps, for the production of homogeneous, functional ZF proteins in high yield (one milligram per liter of bacterial culture), and we demonstrate the generality of this method by applying it to a diverse set of eight C2H2-type ZF proteins. By incorporating a surface-exposed terminal cysteine residue that enables site-specific conjugation with maleimide-activated fluorophores, we confirm the suitability of these probes for in situ labeling of specific DNA sequences in human cells.…”
Get full text

AADL Extension to Model Classical FPGA and FPGA Embedded within a SoC by Dominique Blouin, Daniel Chillet, Eric Senn, Sébastien Bilavarn, Robin Bonamy, Christian Samoyeau

Get full text

PastorC-Tambo: a simplified model to assess carbon balance of dairy farms by G. A. Zurbriggen, A.M. Piazza, S. Montico, K.E. García, J.R. Galli

“…Los sistemas ganaderos pastoriles tienen el potencial de mitigar las emisiones de gases de efecto invernadero (GEI) y mejorar el balance de C mediante el secuestro de C en el suelo. La inclusión del balance de carbono orgánico del suelo (COS) en modelos de escala predial es necesaria para evaluar el balance de C de los sistemas lecheros pastoriles y de base pastoril intensificados. …”
Get full text

Orthogonal validation of PROTAC mediated degradation of the integral membrane proteins EGFR and c-MET by Camilla Ruffilli, Sascha Röth, Noam Zelcer, Kevin Moreau

Subjects: Get full text

Pengaruh Prediksi Missing Value pada Klasifikasi Decision Tree C4.5 by Aji Seto Arifianto, Kursita Dewi Safitri, Khafidurrohman Agustianto, I Gede Wiryawan

“…This study conducted a trial on the development of the C4.5 rule decision tree for chronic kidney disease data. …”
Get full text

Effect of gallic acid on ram semen spermatological parameters at +4 ⁰c storage by Şükrü Güngör, Muhammed Enes İnanç, Ayhan Ata

“…The mixed ejaculates were divided into four equal aliquots and samples were extended with tris containing 0 mM (control), 2 mM, 5 mM, 10 mM gallic acid and they were stored at 4°C. After the groups were created, sperm motility (%), morphologic integrity (%), membrane integrity subjective (Hipo Osmotic Swelling Test, HOS test, %) were examined 24 hour intervals until 96 hour.…”
Get full text

Battery Energy Storage Systems in Microgrids: A Review of SoC Balancing and Perspectives by Thales Augusto Fagundes, Guilherme Henrique Favaro Fuzato, Lucas Jonys Ribeiro Silva, Augusto Matheus dos Santos Alonso, Juan C. Vasquez, Josep M. Guerrero, Ricardo Quadros Machado

Subjects: Get full text

Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis by Aaron A. Jensen, Saba Firdous, Lei Lei, Derek J. Fisher, Scot P. Ouellette

Subjects: Get full text

HISTORY AND RESULTS OF THE INTRODUCTION OF PALMS (ARECACEAE C.H. SCHULTZ) ON THE SOUTHERN COAST OF THE CRIMEA by A. P. Maksimov, Yu. V. Plugata, V. P. Koba, A. F. Khromov

Get full text

p-Uniform Convexity and q-Uniform Smoothness of Absolute Normalized Norms on ℂ2 by Tomonari Suzuki

“…We next give a formulation on absolute normalized norms on ℂ2. Using these, we present some examples of Banach spaces. …”
Get full text

Lack of Association of C677T Methylenetetrahydrofolate Reductase Polymorphism with Breast Cancer Risk in Mali by Brehima Diakite, Yaya Kassogue, Mamoudou Maiga, Guimogo Dolo, Oumar Kassogue, Jane L. Holl, Brian Joyce, Jun Wang, Kadidiatou Cisse, Fousseyni Diarra, Mamadou L. Keita, Cheick B. Traore, Bakarou Kamate, Sidi B. Sissoko, Bourama Coulibaly, Adama S. Sissoko, Drissa Traore, Fatoumata M. Sidibe, Sekou Bah, Ibrahim Teguete, Madani Ly, Sellama Nadifi, Hind Dehbi, Kyeezu Kim, Robert Murphy, Lifang Hou

“…The genotypic distribution of the C677T polymorphism in breast cancer cases was 88.2% for CC, 11.0% for CT, and 0.8% for TT. …”
Get full text

双肢冷弯C形钢柱脚初始刚度 by 陈明, 杨长菲, 任昊, 万馨

Subjects: “…冷弯C形钢…”
Get full text

Evaluation of Effectiveness of Vitamins C and E on Prevention of Renal Scar due to Pyelonephritis in Rat by Fatemeh Emamghorashi, Seyed Mohamad Owji, Mohammad Motamedifar

“…Aim was evaluation of the effects of cosupplementation of, vitamins E and C, in preventing renal scarring in acute pyelonephritis. …”
Get full text

Аналіз грошового обігу Cіверщини  17 ст. за новими скарбовими джерелами by Андрій Клюєв

Get full text

On the coefficients of the expansion of elements from C[0, 1] space by the Faber-Schauder system by M. G. Grigoryan, A. A. Sargsyan

“…Elements (functions) of continuous on [0, 1] functions space (C[0, 1]) are described which have 1/2-monotone coefficients of the expansion by the Faber-Schauder system.…”
Get full text

Experimental and computational investigation of the effect of machining parameters on the turning process of C45 steel by Tien-Thinh Le, Hang Thi Pham, Hiep Khac Doan, Panagiotis G. Asteris

“…In this study, experimental investigations and simulations were conducted to examine the influence of machining parameters during the turning process of C45 medium carbon steel, with the simultaneous application of the Johnson-Cook plasticity model and Johnson-Cook damage model. …”
Get full text

Bilateral Pheochromocytomas in a Patient with Y175C Von Hippel-Lindau Mutation by Olga Astapova, Anindita Biswas, Alessandra DiMauro, Jacob Moalem, Stephen R. Hammes

“…VHL disease is classified into clinical types (1 and 2A-2C) based on this genotype-phenotype relationship. …”
Get full text

Kinetics of Solidification and Crystallization of Liquid Axial Zone of Fe-C Alloys in Cylindrical Molds by V. Khrychikov, O. Semenov, Y. Aftandiliants, S. Gnyloskurenko, T. Semenova, H. Meniailo

Subjects: “…fe-c alloys…”
Get full text