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161
Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review
Published 2020-01-01“…We found high heterogeneity between studies including failure to account for the time/illness of the individuals studied; varied samples and protocols; different clinical classification of TB; different laboratory methods for IP detection, which in turn leads to variable units of measurement and assay sensitivities; and selection bias regarding TST and booster effect. None of the studies adjusted the analysis for the effect of ethnicity. …”
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162
Treatment of e-cigarette use among hospitalised adolescents and young adults: a protocol for intervention development and evaluation of preliminary efficacy and implementation outc...
Published 2025-01-01“…We will develop an evidence-based intervention that includes education, motivational interviewing, quit planning and nicotine replacement therapy prescription offered confidentially in person during the hospital stay and 4 weekly phone booster sessions. Control participants will receive brief advice and quit programme resources. …”
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163
Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:...
Published 2022-06-01“…This combination-immunotherapy regimen will be administered three times every 2 weeks, and booster treatments will be given after 3 and 6 months following the third injection. …”
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164
Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01E vaccine, seasonal malaria chemoprevention and the combination of vaccination...
Published 2020-09-01“…Children in group 1 received three priming doses of RTS,S/AS01E vaccine before the start of the 2017 malaria transmission season and a booster dose at the beginning of two subsequent transmission seasons. …”
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165
Multiple Gene Deletion Mutants of Equine Herpesvirus 1 Exhibit Strong Protective Efficacy Against Wild Virus Challenge in a Murine Model
Published 2025-01-01“…Methods: BALB/c mice were intranasally immunized with a live vToH-QMV or vToH-DMV vaccine. Intranasal booster immunization was given at 14 days post-vaccination (dpv). …”
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166
The effect of meningococcal vaccines on new generation of systemic inflammatory markers in children
Published 2025-01-01“…In this study, in order to support the appropriate use of various MVs in the prevention of meningococcal meningitis (MM), the effects of MVs, especially single-dose and inter-booster administered, on inflammatory parameters in < 5-year-old children were investigated. …”
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167
Robust and Long-Lasting Immunity and Protection in Mice Induced by Lipopolyplex-Delivered mRNA Vaccines Expressing the Prefusion Protein of Respiratory Syncytial Virus
Published 2025-01-01“…Then, we evaluated the effects of the immune response and protection of this mRNA vaccine in mice up to 24 weeks post-vaccination. Following booster immunization, robust and long-lasting RSV pre-F-specific IgG antibodies were detected in the serum of mice, which exhibited Th1/Th2 balanced IgG response and cross-neutralizing antibodies against different subtypes (RSV A2, B18537, and clinical isolate hRSV/C-Tan/BJ 202301), with a clear dose–response relationship observed. …”
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168
A machine learning model to predict the risk factors causing feelings of burnout and emotional exhaustion amongst nursing staff in South Africa
Published 2024-12-01“…Results The gradient booster classifier (GBC) model had the highest accuracy score for predicting both self-reported feelings of burnout (75.8%) and emotional exhaustion (76.8%) from full survey data. …”
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169
Effect of Spine Nerves Muscle Stimulation Combined with Scalp Acupuncture on Shoulder-hand Syndrome after Early Stroke
Published 2019-06-01“…The control group was treated with scalp acupuncture(The scalp movement area was needled and the midline of the vertex, anterior and posterior oblique line of the parietal of the healthy side were located according to the brain functional area)combined with conventional physiotherapy(included passive joint activity, neural booster and neuromuscular electrical stimulation therapy), 2 hours and 45 minutes per day, 5 days per week. …”
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170
Safety and immunogenicity of Ad26.COV2.S in adolescents: Phase 2 randomized clinical trial
Published 2025-12-01“…Adolescents who received a 1-dose primary schedule received a 2.5 × 1010 vp booster dose 6 months later. Safety and humoral immunogenicity were assessed up to 6 months post-last vaccination. …”
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171
Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadthResearch in context
Published 2025-02-01“…All immunogens were co-formulated with liposomal Monophosphoryl-Lipid A (MPLA) adjuvant, and volunteers were followed up for 28 days post final Mosaic booster injection. Participants gave written informed consent to join the study. …”
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172
The effectiveness of providing training and ongoing support to foster cultural humility in volunteers serving as mentors to youth of color: a mixed-methods study protocol
Published 2025-01-01“…., approximately 3 h of initial training that is then supplemented with booster emails and in the context of the contacts that case managers have with mentors routinely in the program). …”
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173
Tick-borne encephalitis vaccination in persons with a recent history of Lyme borreliosis: Insights from a Knowledge, Attitudes and Behaviour survey in Bavaria, Germany
Published 2025-03-01“…Of 228 participants who provided further details, 142 (62 %) reported to have received a regular booster vaccination. Apart from age category and TBD-specific knowledge level, vaccination status was not associated with any other sociodemographic or residence-specific factors, outdoor behaviours, occupational exposure, or prior experiences with ticks or TBDs. …”
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174
A clinical study of the immunogenicity and protective potency of a live recombinant GamLPV vaccine for intranasal use for the prevention of whooping cough in adult volunteers
Published 2024-12-01“…The dynamics of changes in the levels of IgG and IgA antibodies indicates a booster effect after second vaccination. Attenuated B. pertussis bacteria persist in the nose/oropharynx of vaccinated volunteers. …”
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175
Design of an RCT on cost-effectiveness of group schema therapy versus individual schema therapy for patients with Cluster-C personality disorder: the QUEST-CLC study protocol
Published 2022-10-01“…Assessments take place at week 0 (baseline), 17 (mid-GST), 34 (post-GST), 51 (post-booster sessions of GST), and 2 years (FU). Patient characteristics predicting better response to a specific treatment are studied, e.g., childhood trauma, autistic features, and introversion. …”
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176
Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada
Published 2025-02-01“…In period #2, the hazard of infection was higher among HCWs who had COVID-19-infected children at home, whereas the use of protective measures in the community (maintaining social distance, mask-wearing) and receiving a vaccine booster were associated with reduced risk. Providing care to COVID-19 patients was not associated with the risk of acquiring SARS-CoV-2 infection at period #2. …”
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177
Comparison of Long-Term Antibody Titers in Calves Treated with Different Conjunctival and Subcutaneous <i>Brucella abortus</i> S19 Vaccines
Published 2025-01-01“…In this study, a total of 115 calves aged 3 to 4.5 months were created in five groups, with 23 animals in each group: group 1 (vaccine brand A), group 2 (vaccine brand B), and group 3 (vaccine brand C) received the two-dose conjunctival vaccine, group 4 received the single-dose subcutaneous vaccine (vaccine brand C), and group 5 received the subcutaneous vaccine (vaccine brand C) plus the booster dose conjunctival vaccine (vaccine brand B). …”
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178
Improvement and exploration of a water conservation system in the Central Sterile Supply Department (节水型消毒供应中心给水系统改进与探索)
Published 2024-11-01“…Once recovery requirements are met, the water pipes were modified to recover the concentrated water for storage, and the booster pump was used to pipeline the concentrated water to the water consuming point. …”
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