Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal by Leonor Silveira, Miguel Pinto, Joana Isidro, Ângela Pista, Patrícia Themudo, Luís Vieira, Jorge Machado, João Paulo Gomes

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Circle-seq reveals that eccDNA may be a key blood biomarker for HBV-associated liver cancer by Xiao K. Ran, Xiao F. Zhao, Zhen W. Wei, Hua Z. Pang, Yan F. Tang, Rong Liu, Tie X. Wu, Xu D. Liu

“…Following analysis of differential genes using bioinformatics, six candidate genes were screened out based on gene expression and cancer relevance. …”
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Progression of ampC amplification during de novo amoxicillin resistance development in E. coli by Luyuan Nong, Martijs Jonker, Wim de Leeuw, Meike T. Wortel, Benno ter Kuile

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Impact of COVID-19 large scale restriction on environment and economy in Indonesia by R.E. Caraka, Y. Lee, R. Kurniawan, R. Herliansyah, P.A. Kaban, B.I. Nasution, P.U. Gio, R.C. Chen, T. Toharudin, B. Pardamean

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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

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Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology by Alise Zagare, Janis Kurlovics, Catarina Almeida, Daniele Ferrante, Daniela Frangenberg, Armelle Vitali, Gemma Gomez-Giro, Christian Jäger, Paul Antony, Rashi Halder, Rejko Krüger, Enrico Glaab, Egils Stalidzans, Giuseppe Arena, Jens C Schwamborn

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Development of a metabolome-based respiratory infection prognostic during COVID-19 arrival by John I. Robinson, Laura R. Marks, Andrew L. Hinton, Jane A. O'Halloran, Charles W. Goss, Peter J. Mucha, Jeffrey P. Henderson

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Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway by Canghai Guan, Xinlei Zou, Wujiang Shi, Jianjun Gao, Chengru Yang, Yifei Ge, Zhaoqiang Xu, Shaowu Bi, Xiangyu Zhong

“…This study investigates the role and potential mechanisms of metallothionein 1B (MT1B) in MASH through bioinformatics analysis and experimental validation. quantitative reverse transcription PCR and Western blot analyses confirm that MT1B expression is significantly downregulated in liver tissues of MASH patients, in high-fat diet–induced mouse models, and in hepatocytes induced by FFAs. …”
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Comprehensive profiling of gut bacterial communities in hybrid red tilapia with and without streptococcosis by Pathamawan Amthungphong, Natthaphong Sombuttra, Triwit Rattanarojpong, Kanthida Kusonmano, Saengchan Senapin, Satid Chatchaiphan, Watanalai Panbangred, Jirayut Euanorasetr

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Impact of pathogenic mutations of the GLUT1 glucose transporter on solute carrier dynamics using ComDYN enhanced sampling [version 2; peer review: 2 approved, 1 approved with reser... by K. Anton Feenstra, Akiko Higuchi, Kei Yura, Sanne Abeln, Halima Mouhib

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Molecular Characterization of the Onset and Progression of Colitis in Inoculated Interleukin-10 Gene-Deficient Mice: A Role for PPARα by Bianca Knoch, Matthew P. G. Barnett, Janine Cooney, Warren C. McNabb, Diane Barraclough, William Laing, Shuotun Zhu, Zaneta A. Park, Paul MacLean, Scott O. Knowles, Nicole C. Roy

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The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis by Matteo Massara, Michelle Ballabio, Bastien Dolfi, Golnaz Morad, Vladimir Wischnewski, Eleni Lamprou, Joao Lourenco, Stéphanie Claudinot, Hector Gallart-Ayala, Rui Santalla Méndez, Annamaria Kauzlaric, Nadine Fournier, Ashish V. Damania, Matthew C. Wong, Julijana Ivanisevic, Nadim J. Ajami, Jennifer A. Wargo, Johanna A. Joyce

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Mathematical Analysis Of A Modular Network Coordinating The Cell Cycle And Apoptosis by Gheorghe Craciun, Baltazar Aguda, Avner Friedman

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Exact Group Sequential Methods for Estimating a Binomial Proportion by Zhengjia Chen, Xinjia Chen

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Mitochondrial Heterogeneity: Evaluating Mitochondrial Subpopulation Dynamics in Stem Cells by D. C. Woods

“…While it has been well established that mitochondria in different tissues have distinctive ultrastructural features consistent with differential bioenergetic demands, recent and emerging technical advances in flow cytometry, imaging, and “-omics”-based bioinformatics have only just begun to explore the complex and divergent properties of mitochondria within tissues and cell types. …”
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Expression levels of some genes in the MAPK pathway (DUSP1, DUSP2, DUSP4, DUSP6 and DUSP10) in eyelid tumor tissue by Ozmen Esma, Tas Ayca, Akin Dilara Fatma, Erdogan Haydar, Silig Yavuz

“…Additionally, we aim to juxtapose our findings with analyses from various bioinformatics databases.…”
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Eight quick tips for biologically and medically informed machine learning. by Luca Oneto, Davide Chicco

“…While the application of informed machine learning to bioinformatics and health informatics datasets has become more seamless, the likelihood of errors has also increased. …”
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HIGH-THROUGHPUT SIMULATIONS OF PROKARYOTIC COMMUNITY EVOLUTION WITH HAPLOID EVOLUTIONARY CONSTRUCTOR by Z. S. Mustafin, Yu. G. Matushkin, S. A. Lashin

“…The test was performed on a cluster of the Bioinformatics shared access center. The acceleration obtained was almost linear. …”
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Author Correction: Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

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Application of machine learning and genomics for orphan crop improvement by Tessa R. MacNish, Monica F. Danilevicz, Philipp E. Bayer, Mitchell S. Bestry, David Edwards

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