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Accuracy of ESAT6-CFP10 skin test compared with tuberculin skin test in a healthy population: a randomized, blind, parallel controlled phase III clinical study
Published 2024-12-01“…In the second stage, to evaluate whether BCG vaccination affected the efficacy of skin tests, the participants with three negative results in the first stage were randomly assigned to the BCG and placebo groups at a ratio of 2:1 and underwent three tests. …”
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Tuberculosis in Pregnancy: A Review
Published 2012-01-01“…Successful control of TB demands improved living conditions, public enlightenment, primary prevention of HIV/AIDS and BCG vaccination.…”
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Dynamical analysis of a mathematical model on the spread of diphtheria disease with vaccination completeness factors
Published 2024-12-01“…As a result of disruptions in these services, tens of millions of children worldwide are at risk of contracting diphtheria, hundreds of thousands of infants did not receive complete DPT immunization, and more than a million infants missed BCG vaccination at birth. Over the past three years, there has been an increase in mortality rates, reaching 10.6% in 2022. …”
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Clinical Features and Genetic Analysis of 48 Patients with Chronic Granulomatous Disease in a Single Center Study from Shanghai, China (2005–2015): New Studies and a Literature Rev...
Published 2017-01-01“…In addition, septicopyemia, thrush, and hepatosplenomegaly were also commonly observed, accounting for 23%, 23%, and 40% of the cases. Lesions due to BCG vaccination occurred in more than half of the patients. …”
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Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate
Published 2025-01-01“…While all adjuvants were immunogenic, PPE15 with LMQ protected vaccinated mice against an in vivo Mycobacterium tuberculosis challenge, both as a standalone vaccine and as a boost to BCG. Vaccinated mice had enriched lung parenchymal antigen-specific CD4 + CXCR3 + KLRG1− T cells previously associated with TB protection. …”
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Family-Centered Approaches to Pediatric Tuberculosis and Nutritional Challenges in North Aceh: A Qualitative Study
Published 2025-02-01“…Conclusions: The proposed interventions include increasing TB awareness, promoting BCG vaccination, considering socioeconomic factors, enhancing treatment adherence, and integrating nutritional support into management strategies. …”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen
Published 2025-01-01“…Our study suggests a temporal window soon after BCG vaccination, in which STAT1-dependent activation of long-lived resident cells in the tissue mediates localized protection.…”
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