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801
Antidepressant- and Anxiolytic-like Effects in Mice of Alkaloids from Aerial Parts of <i>Argemone platyceras</i> Link & Otto
Published 2025-01-01“…This study aimed to validate the traditional use of aerial parts of <i>A. platyceras</i> Link & Otto in treating these illnesses. <b>Methods:</b> a standardized acidic method to obtain alkaloids was used to obtain an extract (AlkExt), which was tested in adult male Swiss Webster mice in the tail suspension (TST) and forced swimming (FST) tests. …”
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802
cigFacies: a massive-scale benchmark dataset of seismic facies and its application
Published 2025-02-01“…</a>, <a href="#bib1.bibx6">2024</a><a href="#bib1.bibx6">b</a></span>) publicly available for further research and validation of intelligent seismic facies classification.…”
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803
Integrated Analysis of Cell-Free DNA and Novel Protein Biomarkers for Stratification and Therapy Monitoring in Stage IV Pancreatic Cancer: A Preliminary Study
Published 2024-12-01“…In contrast to CA 19-9 kinetics, which were not predictive of outcome, integrated analysis of <i>KRAS</i><sup>mut</sup> cfDNA combined with six evaluated circulating protein biomarkers allowed basal risk stratification at the time of the first follow-up (HR = 10.2, <i>p</i> = 0.0014). <b>Conclusions</b>: A combined longitudinal analysis of <i>KRAS</i><sup>mut</sup> cfDNA with selected protein biomarkers offers significantly improved prognostic value for patients with mPDAC compared to single-parameter methods. …”
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804
Association between instillation time of glaucoma eye drops and their efficacy
Published 2020-06-01“…<p> <br> </p> <p> <b>A.M. Getmanova<sup>1</sup>, A.Yu. Brezhnev<sup>2</sup>, I.R.…”
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805
The adaptation of rainbow trout to warmer water: Oxidative damage in the germinal line
Published 2025-01-01“…Comparisons were made among a) a rainbow trout strain adapted in terms of upper thermal tolerance and higher preferred temperature (Valcheta stream), b) a wild temperate stream population (Guillelmo stream), and c) two temperate farmed strains. …”
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806
Secondary aphakic glaucoma in children: a 15-year retrospective study
Published 2023-06-01“…</p> <p> <b>Conclusion</b>: a less effective visual outcome of aphakic glaucoma treatment is caused by multiple factors, including amblyopia, nystagmus, as well as delayed diagnosis and untimely surgical intervention. …”
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807
Self-induced optical non-reciprocity
Published 2025-01-01“…The self-induced isolation by the input signal is demonstrated with an extremely high isolation ratio of 63.4 dB, a bandwidth of 2.1 GHz for 60 dB isolation, and a low insertion loss of ~1 dB. …”
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808
Evaluation of the Mechanical Properties of Different Dental Resin-Based Materials After Submersion in Acidic Beverages
Published 2024-12-01“…<b>Background</b>: The aim of this study was to evaluate the influence of acidic beverages on the mechanical properties of various dental resin-based materials. <b>Methods</b>: A total number of 160 samples were prepared using four types of resin-based materials—Group A (<i>n</i> = 40): flowable composite, Group B (<i>n</i> = 40): heavy-flow composite, Group C (<i>n</i> = 40): resin-based sealant and Group D (<i>n</i> = 40): nano-hybrid composite. …”
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809
Central corneal thickness to adjust IOP measurements
Published 2020-03-01“…<p> <b>A.V. Korneeva<sup>1</sup>, A.V. Kuroyedov<sup>2,3</sup>, D.N.…”
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810
Role of Vitamin D Status and Alterations in Gut Microbiota Metabolism in Fibromyalgia-Associated Chronic Inflammatory Pain
Published 2025-01-01“…The plasma levels of the SCFAs acetate, butyrate, and propionate were detected by GC-MS. <b>Results</b>: A mean FIQ-R score indicated that the patients could be classified as having moderate FM. …”
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811
Involvement of Cholesterol Metabolic Pathways in Recovery from Noise-Induced Hearing Loss
Published 2020-01-01“…We used miniature pigs exposed to white noise at 120 dB (A) as a model. Auditory brainstem response (ABR) measurements were made before noise exposure, 1 day and 7 days after noise exposure. …”
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812
The Usefulness of Soluble ST2 Concentration in Heart Failure with Reduced Ejection Fraction to Predict Severe Impairment in Exercise Capacity Assessed in Cardiopulmonary Exercise T...
Published 2024-12-01“…Our objective was to evaluate the relationship between the selected cardiopulmonary exercise testing (CPET) parameters and the concentration of novel biomarker sST2 in a group of patients with heart failure with reduced ejection fraction (HFrEF). <b>Methods</b>: A group of 135 patients with HFrEF was enrolled in this prospective cohort study. …”
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813
Ganciclovir Resistance-Linked Mutations in the HCMV <i>UL97</i> Gene: Sanger Sequencing Analysis in Samples from Transplant Recipients at a Tertiary Hospital in Southern Brazil
Published 2025-01-01“…This study aimed to optimize a Sanger sequencing protocol for analyzing GCV resistance-linked mutations in the HCMV <i>UL97</i> gene from plasma samples of transplant patients treated at Hospital de Clínicas de Porto Alegre, Rio Grande do Sul, Brazil. <b>Methods:</b> A nested-PCR approach combined with a touchdown PCR method was employed to enhance the sensitivity and specificity of the sequencing analysis. …”
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814
Development of a pandemic-related core set of quality indicators for quality and patient safety in University Hospitals in Germany
Published 2025-01-01“…This initial set of indicators was refined through consultations with a) quality and risk management officials from German university hospitals via an online survey and b) a diverse panel of experts. Results The comprehensive evaluation identified two primary strands: organizational/management indicators (Strand A, 60 indicators) and disease-specific clinical quality and patient safety indicators (Strand B, 20 indicators for critical conditions like stroke, myocardial infarction, and cancer.) …”
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815
Translation and Validation of the Italian Version of the Team-Based Learning Student Assessment Instrument (TBL-SAI) in Nursing Students
Published 2025-01-01“…The aim of this study is to validate the Italian version of the Team-Based Learning Student Assessment Instrument (TBL-SAI) among nursing students. <b>Methods</b>: A methodological-driven translation process and a cross-sectional study design were used. …”
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816
Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites
Published 2025-01-01“…Abstract In this study, novel polyaniline-coated perovskite nanocomposites (PANI@CoTiO3 and PANI@NiTiO3) were synthesized using an in situ oxidative polymerization method and evaluated for the photocatalytic degradation of Rhodamine B (RhB) a persistent organic pollutant. The nanocomposites displayed significantly enhanced photocatalytic efficiency compared to pure perovskites. …”
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817
Distribution of Major HLA-A, -B, -DR, and -DQ Loci Potentially Associated with Multiple Sclerosis in a Healthy Population from Southern Morocco
Published 2025-01-01“…<b>Materials and Methods:</b> A cross-sectional study was carried out over the 2016–2023 period on 685 Moroccan healthy individuals, including 355 males and 330 females. …”
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818
Advancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review
Published 2025-01-01“…Additionally, it evaluates HYA’s impact—alone or in combination with other products—on hard and soft tissue dimensional changes, early wound healing, and implant success rates. <b>Methods</b>: A comprehensive electronic literature search was conducted, and studies meeting the inclusion criteria were critically evaluated. …”
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819
Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy
Published 2025-01-01“…We previously identified <b>LSO-24</b>, a hydroxy-1,2,3-triazole-based compound, as a modest potentiator of p.Arg334Trp-CFTR, a variant with a conductance defect for which no modulator therapy is currently approved. …”
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820
Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma
Published 2025-02-01“…Mechanistically, hepatocyte nuclear factor 1β (HNF1B), a transcription factor highly expressed in ccRCC, is succinated by DMF at cysteine residues, leading to its proteasomal degradation. …”
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