A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Dia... by Hidetoshi Akimoto, Emi Fukuda-Kawaguchi, Omar Duramad, Yasuyuki Ishii, Kazunari Tanabe

“…Herein, we report that RGI-3100-iB, a novel liposomal formulation carrying both α-galactosylceramide (α-GalCer), which is a representative ligand for invariant natural killer T (iNKT) cells, and insulin B chain 9–23 peptide, which is an epitope for CD4+ T cells, could induce the accumulation of regulatory T cells (Tregs) in islets in a peptide-dependent manner, followed by the remarkable prevention of diabetes onset in nonobese diabetic (NOD) mice. …”
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A novel mode of histone-like protein HupB regulating Sinorhizobium meliloti cell division through lysine acetylation by Ningning Li, Huibo Jin, Hongbo Li, Huilin Yu, Xiaoxu Wu, Tianci Zhang, Liangliang Yu, Zhaoling Qin, Li Luo

“…In this study, we find that stimulation of lysine acetylation or non-acetylation in HupB, a homolog of HU, differentially regulates the expression of cell cycle regulators, as well as cell growth and division in Sinorhizobium meliloti. …”
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Frailty and Sarcopenia Assessment in Patients with Advanced Chronic Liver Disease in a Tertiary Center in Romania by Petruta Violeta Filip, Denisa Cuciureanu, Corina Silvia Pop, Andreea Nicoleta Marinescu, Florentina Furtunescu, Laura Sorina Diaconu

“…Furtherksdnvk more, our purpose is to explore the association between sarcopenia, frailty, and various complications and the impact of these conditions on short- and long-term hospital survival rates. <b>Methods</b>: A prospective, observational, unicentric study was conducted in an emergency university hospital in Romania between January 2021 and December 2023 that included patients with advanced liver diseases. …”
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Knowledge, Awareness, and Influence of the COVID-19 Pandemic on Students of Biomedical Faculties: A Cross-Sectional Study by Bruno Špiljak, Luka Šimunović, Ana Marija Miličević, Marko Granić, Lana Bergman, Jasminka Peršec

“…This study aimed to explore and compare differences in knowledge, awareness, behavior, and the psychological impact of the pandemic among students of biomedical faculties at the University of Zagreb. <b>Methods</b>: A cross-sectional study was conducted between 27 November 2020 and 19 January 2021 involving 518 students from the School of Dental Medicine, School of Medicine, Faculty of Pharmacy and Biochemistry, and Faculty of Veterinary Medicine. …”
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Occupational noise-induced hearing loss in China: a systematic review and meta-analysis by Yong Hu, Jiena Zhou, Zhihao Shi, Lifang Zhou, Meibian Zhang

“…This study aimed to analyse the prevalence and characteristics of occupational NIHL in the Chinese population using data from relevant studies.Design Systematic review and meta-analysis.Methods From December 2019 to February 2020, we searched the literature through databases, including Web of Science, PubMed, MEDLINE, Scopus, the China National Knowledge Internet, Chinese Sci-Tech Journal Database (weip.com), WanFang Database and China United Library Database, for studies on NIHL in China published in 1993–2019 and analysed the correlation between NIHL and occupational exposure to noise, including exposure to complex noise and coexposure to noise and chemicals.Results A total of 71 865 workers aged 33.5±8.7 years were occupationally exposed to 98.6±7.2 dB(A) (A-weighted decibels) noise for a duration of 9.9±8.4 years in the transportation, mining and typical manufacturing industries. …”
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Dual band four port MIMO antenna with dual circular polarization for Wi-Fi/WiMAX applications by Poonam Thanki, Trushit Upadhyaya, Upesh Patel, Khaled Aliqab, Meshari Alsharari, Ayman A. Althuwayb, Ammar Armghan, Vishal Sorathiya

“…The measured findings demonstrate the circular polarization, 3-dB axial ratio beamwidth, impedance bandwidth of 2.11 GHz −2.42 GHz and 3.40 GHz-3.51 GHz, adequate axial ratio bandwidth (ARBW) of the suggested MIMO antenna along with high isolation of −17 dB, gain of 3.43 and 2.09 dBic at 2.4 GHz and 3.5 GHz respectively, TARC (Total active reflection coefficient) of less than 0 dB, a CCL (Channel capacity loss) of lesser than 0.4 bits/sec/Hz, and an MEG (Mean effective gain) value of less than 3 dB.…”
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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

“…Bioinformatic analysis revealed the differential expression of the histone demethylase JMJD2B/KDM4B, a well-known epigenetic modulator that leads to the demethylation of different lysine residues on histones, in IL-13-treated lung fibroblasts. …”
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Investigating the Role of Osteopontin (OPN) in the Progression of Breast, Prostate, Renal and Skin Cancers by Gautam Kundu, Selvakumar Elangovan

“…<b>Methods</b>: In this study, we conducted a further examination of the transcriptomic expression profile of SPP1 (Osteopontin) during the progression of cancer in four human tissues, breast, prostate, renal and skin, in order to understand the circumstances conducive to its activation and dysregulation, the biological pathways and other mechanisms involved as well as differences in its splicing patterns influencing its expression and functionality. <b>Results</b>: A significant overexpression of SPP1, as well as a set of other highly correlated genes, was seen in most of these tissues, indicating their extensive implication in cancer. …”
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Revisiting Fat Graft Harvesting and Processing Technique to Optimize Its Regenerative Potential by Karina Karina, MD, PhD, Johannes A. Biben, MD, Krista Ekaputri, MD, Grady Krisandi, BMed, Imam Rosadi, MSc, Siti Sobariah, BSc, Irsyah Afini, MBiomed, Tias Widyastuti, BSc, Alfida Zakiyah, BSc, Difky Ernanda, BSc

“…Fat was harvested from patients undergoing fat grafting using 2 types of liposuction cannula: (A) a 3-mm blunt tip cannula with 3 smooth holes and (B) a 2.4-mm, sharp point port, multihole blunt tip cannula. …”
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The Use of SGLT-2 Inhibitors and GLP-1RA in Frail Older People with Diabetes: A Personalised Approach Is Required by Alan J. Sinclair, Ahmed H. Abdelhafiz

“…<b>Objectives:</b> To review the characteristics and phenotype of frail older people with diabetes who should benefit from the use of SGLT-2 inhibitors or GLP-1RA. <b>Methods:</b> A narrative review of the studies investigating the benefits of SGLT-2 inhibitors and GLP-1RA in frail older people with diabetes. …”
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Comparison of cultural and immunological methods for the evaluation of foodborne intoxications risk caused by staphylococcus aureus in white cheese, raw milk, minced meat and inego... by Nihat Telli, Nuray Gamze Yörük, Arife Ezgi Telli, Muhammed Ali Cebirbay, Ahmet Güner

“…<p> <b>Materials and Methods:</b> A total of 200 samples including white cheese (n=50), raw milk (n=50), ground meat (n=50) and İnegöl meatballs (n=50) were collected. …”
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HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats by Dahu Liang, Zijing Wu, Yanhao Liu, Chao Li, Xianghong Li, Bin Yang, Haitang Xie, Hua Sun

“…Schisandrol B, a lignan isolated from dried Schisandra chinensis fruits, has been shown to exhibit hepatoprotective, cardioprotective, renoprotective, and memory-enhancing properties. …”
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The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis by Mubara Azhar, Mohammed S. Alasmari, Ammara Zamir, Hamid Saeed, Faleh Alqahtani, Tanveer Ahmad, Muhammad Fawad Rasool

“…This systematic review aims to provide detailed knowledge about the pharmacokinetics (PK), the associated pharmacodynamics (PD), and the drug interactions of GLM, which can be used to assess key parameters and identify factors influencing variability across diverse populations and clinical settings. <b>Methods:</b> A systematic search of the peer-reviewed literature was combined using major databases—Google Scholar, PubMed, Cochrane, and ScienceDirect, to identify studies reporting the PK of GLM. …”
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In Vitro Evaluation of Leakage at Implant-Abutment Connection of Three Implant Systems Having the Same Prosthetic Interface Using Rhodamine B by Antoine Berberi, Georges Tehini, Khaldoun Rifai, Farah Bou Nasser Eddine, Nabil El Zein, Bassam Badran, Haidar Akl

“…Microbial colonization of the interfacial gap may ultimately lead to infection and bone resorption. Using Rhodamine B, a sensitive fluorescent tracer dye, we aim in this study to investigate leakage at implant-abutment connection of three implant systems having the same prosthetic interface. …”
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CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

“…Here, we focused on the biological function and regulatory mechanism of circBAZ1B, a circRNA derived from the bromodomain adjacent to the zinc finger domain 1B (BAZ1B) gene, in MI/RI progression. …”
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Clinical Characteristics and Outcomes in Heart Failure Patients with Implantable Pulmonary Artery Pressure Monitors: A Single Centre Irish Experience by Niall Leahy, Cillian O’Brien, Sara Essa Alsubai, Eileen Coen, Darragh Murphy, Faisal Sharif

“…Intracardiac and pulmonary artery pressure (PAP) monitoring can help predict heart failure decompensation, as changes in these haemodynamics occur before clinical congestion manifests. <b>Methods:</b> A retrospective single centre analysis of patients who underwent insertion of the Cordella™ PA Sensor System (Endotronix, Inc., Chicago, IL, USA) in University Hospital Galway, Ireland, as part of three separate clinical trials—SIRONA 1, SIRONA 2, PROACTIVE HF, was performed. …”
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Air Particle Abrasion in Dentistry: An Overview of Effects on Dentin Adhesion and Bond Strength by Andreea Kui, Smaranda Buduru, Anca Labuneț, Sorina Sava, Dalia Pop, Iris Bara, Marius Negucioiu

“…This review evaluates the influence of APA on dentin adhesion. <b>Methods</b>: A systematic literature search from 2018 to 2023 was conducted according to PRISMA-ScR guidelines. …”
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Effects of Lemon Beverage Containing Citric Acid with Calcium Supplementation on Bone Metabolism and Mineral Density in Postmenopausal Women: Double-Blind 11-Month Intervention Stu... by Hiromi Ikeda, Tadayuki Iida, Masanori Hiramitsu, Takashi Inoue, Satomi Aoi, Miho Kanazashi, Fumiko Ishizaki, Toshihide Harada

“…The LECA group also showed significant decreases in concentrations of tartrate-resistant acid phosphatase 5b (TRACP-5b), a bone resorption marker, and bone alkaline phosphatase (BAP) as compared to the other groups, as well as a significant decrease in concentration of osteocalcin (OC), a bone formation marker, as compared to the LE group. …”
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Pain Reduction in Patellofemoral Knee Patients During 3-Month Intervention with Biomechanical and Sensorimotor Foot Orthoses: A Randomized Controlled Clinical Study by Steven Simon, Andreas Heine, Jonas Dully, Carlo Dindorf, Oliver Ludwig, Michael Fröhlich, Stephan Becker

“…Therefore, this study addresses the impact of biomechanical foot orthoses (BMFOs) and sensorimotor foot orthoses (SMFOs) on patients with foot deformity and PFP. <b>Methods:</b> A total of 26 participants (9 men, 17 women; 27.7 ± 10.7 years; 175.0 ± 0.1 cm; 75.7 ± 18.8 kg; BMI: 24.7 ± 5.6) took part in this randomized controlled clinical trial. …”
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Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype. by Florence E McLean, Brian R Omondi, Nouhoum Diallo, Stanley Otoboh, Carolyne Kifude, Abdirahman I Abdi, Rivka Lim, Thomas D Otto, Ashfaq Ghumra, J Alexandra Rowe

“…Two of these were of the predicted DC11 type (one showing the dual rosetting/IgM-Fc-binding phenotype), whereas two contained DC15 (DBLα1.2-CIDRα1.5b) a PfEMP1 type not previously associated with rosetting. …”
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