Primary cutaneous gamma–delta T cell lymphoma presenting as a leg ulcer in a kidney transplant recipient on hemodialysis: a case report with a literature review by Yuki Oba, Hiroki Mizuno, Shigekazu Kurihara, Daisuke Ikuma, Masayuki Yamanouchi, Tatsuya Suwabe, Katsuyuki Miki, Kei Kono, Kennichi Ohashi, Aya Nishida, Atsushi Wake, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa

“…Although he decided to undergo amputation of his right leg finally, he died following postoperative cytomegalovirus meningitis. …”
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Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana by Kwame Yeboah, Jennifer A. Agyekum, Richard N. A. Owusu Mensah, Patrick K. Affrim, Linda Adu-Gyamfi, Rita O. Doughan, Afua B. Adjei

“…Peripheral sensory neuropathy (PSN) is among microvascular complications of diabetes that make patients prone to ulceration and amputation. Arterial stiffness is a predictor of cardiovascular diseases and microvascular complications associated with diabetes. …”
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A META-ANALYSIS: THE UTILIZATION OF NEGATIVE PRESSURE WOUND THERAPY IN DIABETIC FOOT ULCERS by Ni Putu Gita Raditya Sanjiwani, I Putu Krisna Murti

“…The random effect model used in the analysis revealed a statistically significant discrepancy in the healing rate that had negative pressure wound therapy (NPWT) intervention with the healing rate analysis shows OR 0.77 [0.65, 0.90] p=0.0, and other outcome analysis shows no statistically significant result, adverse event incident OR  0.01 CI [0.00 to 0.04), p =0.23, and amputation rate was OR 0.01 CI [0.00 to 0.02] p = 0.81. …”
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Surgical sharp debridement alongside maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs): A systematic review of case reports by Babak Choobi Anzali, Anna Javanbakht, Maryam Rasouli, Nasim Talebiazar, Milad Hashemzadeh, Mir Amir Hossein Seyed Nazari

“…The narrative synthesis identified several key findings, including significant wound size reduction, improved glycemic control, disappearance of foul odor, improved healing rates, infection control, granulation tissue formation, epithelialization, complete wound closure, avoidance of amputation, and pain alleviation. The combination therapy showed promise in managing DFUs effectively. …”
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Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound by Irene Degli Agosti, Elena Ginelli, Bruno Mazzacane, Gabriella Peroni, Sandra Bianco, Fabio Guerriero, Giovanni Ricevuti, Simone Perna, Mariangela Rondanelli

“…A 46-year-old man had a motorcycle accident and underwent amputation of the right tibia and fibula. At the discharge he came to our attention to start rehabilitation treatment. …”
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Derivation of Sa-MoDEI score from DEI. Tak for prognostication in Buerger's Disease - Preliminary data of a prospective observational cohort by Gregory Pathrose, Albert A Kota, Prabhu Premkumar, Prasanna Samuel, Shivraj Padiyar, Deepak Selvaraj, Prasanta Padhan, Debashish Danda

“…They were followed up for 12 months after baseline scoring. Amputation was considered a bad outcome. The receiver operating characteristic curve was used to delineate a specific cut-off Sa-MODEI score to define bad outcomes. …”
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Minimally Invasive Fetoscopic Resection of Life-Threatening Amniotic Band Constrictions in a Human Fetus at 22 + 2 Weeks of Gestation Complicated by Subtotal Chorioamniotic Separat... by Nadja Riehle, Oliver Nowak, Leila Messroghli, Samantha Wakerlin, Thomas Schaible, Thomas Kohl

“…If detected early enough, select cases may benefit from prenatal resection of the amniotic bands, thus preventing amputation and fetal death. Yet, especially in the presence of complete chorioamniotic separation, these procedures are rare, technically difficult, and not without significant risk. …”
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Prevalence, Patterns, and Factors Associated with Peripheral Neuropathies among Diabetic Patients at Tertiary Hospital in the Kilimanjaro Region: Descriptive Cross-Sectional Study... by Ahlam A. Amour, Nyasatu Chamba, Johnstone Kayandabila, Isaack A. Lyaruu, Dekker Marieke, Elichilia R. Shao, William Howlett

“…Diabetic peripheral neuropathy (DPN) is a common microvascular complication of diabetes mellitus (DM) and may progress to diabetic foot, which frequently leads to amputation and/or disability and death. Data is scanty on the burden of diabetic peripheral neuropathy in Tanzania. …”
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FACTORS INFLUENCING SKIN NECROSIS RESULTING FROM EXTRAVASATION INJURIES AND THE RAPEUTIC APPROACHES IN THE PEDIATRIC INPATIENT WARD (JANUARY-DECEMBER 2019) by Iswinarno Doso Saputro, Agus Santoso Budi, Dhitta Aliefia Noverta

“…Abstract: Introduction: Extravasation injury, a common complication of intravenous therapy in children, Interestingly, the complications arising from extravasation injuries could be more severe than the underlying medical conditions, sometimes even requiring amputation. The study aimed to identify the factors influencing the occurrence of skin necrosis due to extravasation injuries and to categorize the treatment approaches employed at Dr. …”
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А method of surgical correction of genital prolapse in combination with elongation and cicatricial deformation of the cervix in patients of reproductive age. A retrospective study by Albina Kh. Karanasheva, Yulia E. Dobrokhotova

“…This method of surgical treatment makes it possible to recreate the anatomy of the cervix with native tissues without its amputation. It has no unfavorable obstetric outcomes and can be used in women interested in reproductive function.…”
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Application of 3D-printed porous prosthesis for the reconstruction of infectious bone defect with concomitant severe soft tissue lesion: a case series of 13 cases by Zhuo Chen, Yiyuan Yang, Bingchuan Liu, Xingcai Li, Yun Tian

“…Two patients experienced recurrent infections leading to prosthesis removal and debridement surgery, with the infection ultimately eradicated in one and the other undergoing amputation. Three patients experienced noninfectious flap-related complications, however, all eventually healed through surgical intervention. …”
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Peripheral Arterial Disease and Its Associated Factors among Type 2 Diabetes Mellitus Patients at Debre Tabor General Hospital, Northwest Ethiopia by Yonas Akalu, Ambaye Birhan

“…Peripheral arterial disease (PAD), one of the major macrovascular complications of diabetes, is associated with cardiovascular mortality and a high rate of disability following the amputation of an extremity in diabetes patients. However, there is no data on the prevalence of PAD among type 2 diabetes patients in Ethiopia. …”
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Single-Institution Experience With Nononcologic Total Femoral Replacement by Ryan Ouillette, MD, Kevin Chen, BA, Matthew Dipane, BA, Alexander Christ, MD, Edward McPherson, MD, Alexandra Stavrakis, MD

“…Despite a high complication profile, only 1 patient underwent limb amputation and there was only 1 mortality during the study period. …”
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Place of injuries of elbow joint in the structure of primary permanent disability among Ukrainian population by L.Y.  Naumenko, T.O. Zub, A.O. Mametyev

“…Consequences of elbow injuries which led to primary permanent disability were caused by bone fractures (61.5%), elbow contractures and elbow ankyloses (19.0%), injuries of an ulnar nerve (8.7%), traumatic amputation at the elbow level (6.2%), forearm dislocations (3.1%), open wounds of elbow (1.0%), elbow ligaments ruptures (0.5%). …”
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Endovascular Treatment and Outcomes for Femoropopliteal In-Stent Restenosis: Insights from the XLPAD Registry by Michael H. Vu, Glaiza-Mae Sande-Docor, Yulun Liu, Shirling Tsai, Mitul Patel, Chris Metzger, Mehdi H. Shishehbor, Emmanouil S. Brilakis, Nicolas W. Shammas, Peter Monteleone, Subhash Banerjee

“…Primary endpoint included major adverse limb events (MALE) at 1 year, a composite of all-cause death, target limb repeat revascularization, or major amputation. Results. ISR patients were more frequently on antiplatelet (94.5% vs 89.4%, p=0.007) and statin (68.9% vs 60.3%, p=0.003) therapies. …”
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Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…Analysis showed that the global research hotspots of DFU focused on lower limb amputation, diabetic foot infection, and treatment and management of DFU. …”
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DENND5B Gene Expression as a Trigger for the Development of Diabetes Mellitus–Peripheral Artery Disease: Insights from a Univariate and Multivariate Mendelian Randomization Study by Qiaoqiao Li, Fuli Cao, Xueping Gao, Yuan Xu, Bo Li, Tianyang Hu

“…Compared to individuals with PAD but no DM, those with concurrent DM and PAD (DM-PAD, diabetes mellitus–peripheral artery disease) face a seven-fold higher risk of critical limb ischemia and a five-fold higher risk of amputation. However, the pathogenic factors and effective therapeutic targets for DM-PAD still remain elusive. …”
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Temporary ectopic banking as a treatment option for mangled thumb: a case report by Meisam Jafari Kafiabadi, Adel Ebrahimpour, Seyyed Hamidreza Ayatizadeh, Reza Fereidooni, Amirhossein Kamalinia, Mehrdad Sadighi, Farsad Biglari, Seyed Arman Moein

“…Necrosis necessitated amputation through the first metacarpophalangeal joint. …”
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A Novel Chemically Modified Curcumin “Normalizes” Wound-Healing in Rats with Experimentally Induced Type I Diabetes: Initial Studies by Yazhou Zhang, Steve A. McClain, Hsi-Ming Lee, Muna S. Elburki, Huiwen Yu, Ying Gu, Yu Zhang, Mark Wolff, Francis Johnson, Lorne M. Golub

“…Impaired wound-healing in diabetics can lead to life-threatening complications, such as limb amputation, associated in part with excessive matrix metalloproteinase- (MMP-) mediated degradation of collagen and other matrix constituents. …”
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Effectiveness of an Innovative Pulsed Electromagnetic Fields Stimulation in Healing of Untreatable Skin Ulcers in the Frail Elderly: Two Case Reports by Fabio Guerriero, Emanuele Botarelli, Gianni Mele, Lorenzo Polo, Daniele Zoncu, Paolo Renati, Carmelo Sgarlata, Marco Rollone, Giovannoi Ricevuti, Niccolò Maurizi, Matthew Francis, Mariangela Rondanelli, Simone Perna, Davide Guido, Piero Mannu

“…Despite appropriate treatment, the ulcers showed little improvement and the risk of amputation was high. Both patients underwent daily EBS therapy and standard dressing. …”
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