Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia by Teik K. Ho, X. Shiwen, D. Abraham, J. Tsui, D. Baker

“…In a large percentage of these patients, lower limb amputation is still required. Studies of ischaemic skeletal muscle disclosed evidence of endogenous angiogenesis and adaptive skeletal muscle metabolic changes in response to hypoxia. …”
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Pengembangan Deep Learning untuk Sistem Deteksi Dini Komplikasi Kaki Diabetik Menggunakan Citra Termogram by Medycha Emhandyksa, Indah Soesanti, Rina Susilowati

“…Abstract The prevalence of diabetic foot complications globally reaches 66% with a 20 times higher risk of amputation in patients with diabetes mellitus. Preventive measures through early detection of diabetic foot complications are necessary to minimize the risk of amputation. …”
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Association between clinical and sonographic patterns of major peripheral arterial occlusion among patients presenting with lower limb dry gangrene at a single center in Western Ug... by Alfred Omo, Emmanuel Barasa, Edson Tayebwa, Moses Acan, Emile Ndanga, Aturinde Mercy

“…It is among the leading indications for lower limb amputation; however, in situations where timely access of accurate diagnostic and revascularization services are limited, irrational amputations are performed based on mere physical assessment of a specific occluded major arterial segment, consequently preceded with gangrene recurrence on the same limb stump due to physical examination inaccuracies. …”
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Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity by X. H. Li, L. Y. Guan, H. Y. Lin, S. H. Wang, Y. Q. Cao, X. Y. Jiang, Y. B. Wang

“…Using ROC statistic, a cut-off value of 5.13 g/L indicated the possible amputation with a sensitivity of 81.8% and a specificity of 78.9% (positive predictive value [PPV] 78.6%, negative predictive value [89.0%]). …”
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A one-two punch of inflammation and oxidative stress promotes revascularization for diabetic foot ulcers by Li Chen, Yunrong Li, Xuanxuan Zhang, Lixin Ma, Cheng Zhang, Huanhuan Chen

“…Patients with diabetic foot ulcers (DFU) suffering from severe lower limb ischemia face the risk of amputation. Concomitant oxidative stress and hyperinflammation commonly manifest within the tissue affected by DFU, exacerbating the deterioration of DFU wounds. …”
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Digital Gangrene: An Unusual Manifestation of Non-Hodgkin Lymphoma by Muhammad Shoaib Momen Majumder, Shamim Ahmed, Tajkia Haque, Syed Atiqul Haq, Saumitra Chakravarty, Md. Abu Shahin, Din-E-Mujahid Mohammad Faruque Osmany, Johannes J. Rasker

“…The digital ischemia worsened despite cessation of cannabis and methamphetamine and starting CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone) treatment, making amputation necessary. Conclusion. We present, to our knowledge, the first report of peripheral T cell lymphoma, NOS presenting with gangrene in all digits complicated by methamphetamine and cannabis abuse. …”
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OSTEOSARCOMA HAS NOT BECOME ATTENTION TO SOCIETY PROFILE OF OSTEOSARCOMA PATIENTS AT DR. SOETOMO GENERAL HOSPITAL SURABAYA "A RETROSPECTIVE STUDY” by Ferdiansyah Mahyudin, Mouli Edward, Muhammad Hardian Basuki, Yunus Abdul Bari, Yesa Suwandani

“…Osteosarcoma treated mostly by amputation, either with or without chemotherapy. The survival rate in the first, second, or the fifth year was found lower than other references. …”
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A CASE REPORT: RISK OF ELECTRIC INJURY ON DELAYED INITIAL TREATMENT by Ulfa Elfiah, Dissa Yulianita Suryani

“…Treatment of electric injuries often involves various surgical procedures, including skin grafts, flaps, or amputation, depending on the severity of the injury. …”
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Our experience of treatment of purulent arthritis in lower extremities after burn injury by B.M. Shakirov, D.Sh. Karabaev, S.X. Zoxidova, Sh. Ziyadullaev

“…Unfortunately we performed amputation in 8 patients. Results: In the postoperative period, drainage of the joint cavity through the opening and wound, the application of paraphene to the surrounding tissues of the joints, massage, physical therapy, treatment physical physiotherapy exercises, laser application made it possible to achieve satisfactory results. …”
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An explainable deep learning model for diabetic foot ulcer classification using swin transformer and efficient multi-scale attention-driven network by R. Karthik, Armaano Ajay, Anshika Jhalani, Kruthik Ballari, Suganthi K

“…Severe cases of DFU can lead to lower limb amputation in diabetic patients, making their diagnosis a complex and costly process that poses challenges for medical professionals. …”
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Static Magnetic Field Accelerates Diabetic Wound Healing by Facilitating Resolution of Inflammation by Wenlong Shang, Guilin Chen, Yinxiu Li, Yujuan Zhuo, Yuhong Wang, Zhicai Fang, Ying Yu, Huiwen Ren

“…Impaired wound healing is commonly encountered in patients with diabetes mellitus, which may lead to severe outcomes such as amputation, if untreated timely. Macrophage plays a critical role in the healing process including the resolution phase. …”
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Percutaneus Transluminal Angioplasty Using Carbon Dioxide Contrast in Chronic Limb Threatening Ischemia patient with Renal Failure by Saga Malela Aria Sabara, Suko Adiarto

“…Chronic limb-threatening ischemia (CLTI) represents the end stage of PAD often need lower extremity amputation, and the aftermath can be worse. For the patient with CLTI and chronic renal disease (CKD) who need endovascular therapy, iodinated contrast may enhance the risk of contrast-induced nephropathy (CIN). …”
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A rare case of Ewing's sarcoma in a 4-year-old child treated by tumor endoprosthetics using 3D printing by Vladimir Stavrev, Luben Stokov, Petko Ganev, Georgi Georgiev

“…In another medical facility, he was offered amputation. Our team decided to use the "3D printed tumor megaendoprosthesis, double growing, from the Czech company Prospon. …”
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Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening by Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Kamarajan Rajagopalan, Johnson Retnaraj Samuel Selvan Christyraj

“…Remarkably, the posterior region of the prostate gland demonstrated significant regenerative capacity, with complete regeneration occurring within 45 days following amputation. Furthermore, treatment with valproic acid enhanced posterior regeneration, leading to full restoration within 12 days. …”
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Sheikh al-Qaraḍāwī’s Independent Reasoning (Ijtihād) in Reformulating Contemporary Islamic Criminal Jurisprudence within the Framework of the Modern State by Gaber Mohamed

“…Al-Qaraḍāwī’s views covered a range of complex criminal issues, including his stance on abolishing the death penalty, gender equality in matters of blood money, retribution between Muslims and non-Muslims, the changing jurisprudential concept of guardianship in retribution cases, the minimum threshold for amputation on theft, criticism of the modern prison system, punishment by stoning, the crime of apostasy, and his critique of the prevailing European narrative on corporal punishments in Islam. …”
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Complications In The Management Of High-Energy Closed Fractures Of Proximal Tibial Plateau. A Retrospective Study by Rahman Rasool Akhtar, Waqas Ali, Riaz Ahmed, Muhammad Nadeem Kashmiri, Hira Waris, Muhammad Haider

“…Routine dressing changes and antibiotic treatment were carried out in patients who had superficial infections.9 out of 25 patients who had faced a deep-seated infection underwent repeated implant removal, debridements, amputation, and flap covering depending on the reaction of the host. …”
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Rotationplasty for Unplanned Fixation of Pathological Fracture Distal Femoral Osteosarcoma by Chindanai Hongsaprabhas, Wittavat Chenboonthai, Phoomchai Suvaraksakul, Chris Charoenlap

“…Therefore, awareness of the pathological fracture should initially be taken into account to prevent inappropriate fixation which could result in an unnecessary amputation.…”
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Prevalence of Chronic Complications, Their Risk Factors, and the Cardiovascular Risk Factors among Patients with Type 2 Diabetes Attending the Diabetic Clinic at a Tertiary Care Ho... by Maulee Hiromi Arambewela, Noel P. Somasundaram, Hettiarachchige Buddhi Pradeep Ranjan Jayasekara, Mahesh P. Kumbukage, Pulukkutti Mudiyanselage Sarath Jayasena, Chandrasekara Mudalige Priyanka Hemanthi Chandrasekara, Kurukulasuriya Ravindra Alexis Sudath Fernando, Divadalage Priyantha Kusumsiri

“…Prevalence of CAD, stroke, and peripheral vascular disease were 10.6%, 1.1%, and 4.7% while diabetic retinopathy, neuropathy, nephropathy, diabetic foot, and lower extremity amputation (LEA) were 26.1%, 62.6%, 50.8%, 2.6%, and 1.3%, respectively. …”
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CLINICAL PROFILES OF FROSTBITE IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL: A CASE SERIES by Thomas Eduardus Sudrajat Wahyu Nugroho, Beta Subakti Nata’atmadja

“…They were admitted to our facility 11st days after the injury, with one patient undergoing finger amputation on the 71st day. All received standard antibiotics and three days of hospital care. …”
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