Necrotising Myositis, the Deadly Impersonator by A. Rahman, A. K. Abou-Foul, A. Yusaf, J. Holton, L. Cogswell

“…Patient 1 had a high above knee amputation of the left leg with extensive debridement of the right. …”
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3D-Printed Customized Cages for Foot Arthrodesis by Iozefina Botezatu, Dan Lăptoiu, Diana Popescu, Rodica Marinescu

“…It is the first review to gather data on the use of such customized implants in foot arthrodesis, providing critical insights to enhance their application, including amputation avoidance. This study highlights the advantages of personalized 3D-printed implants in achieving a better anatomical fit, improving clinical outcomes, and ensuring faster recovery times, while also addressing considerations such as the cost and the need for long-term clinical data.…”
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Hyperbaric oxygen therapy for the treatment of a crush injury of the hand: a case report by Pedro Henry Neto, Zamara Brandão Ribeiro, Adriano Bastos Pinho, Carlos Henrique Rodrigues de Almeida, Carlos Alberto de Albuquerque Maranhão, Joaquim da Cunha Campos Goncalves

“…He sustained a crush injury to his right hand and presented with significant muscle damage, including multiple fractures and dislocations, an avulsion injury of the flexor tendons, and amputation of the distal phalanx of the little finger. …”
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TRANSMETACARPAL REPLANTATION. ELEVEN YEARS LATER by Binka Popova, Elena Mateva, Kevork Kaykchian, Deyan Sokolov

“…In February 2012 he sustained transmetacarpal amputation by circular saw through the proximal third of the left hand, with local crush of the tissues. …”
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Natural <i>Bletilla striata</i> Polysaccharide-Based Hydrogels for Accelerating Hemostasis by Hui-Fang Lin, Yue-Yue Wang, Feng-Zhen Liu, Zi-Wei Yang, Hao Cui, Si-Yu Hu, Feng-He Li, Pei Pan

“…Furthermore, the hydrogels demonstrated superior hemostatic qualities in an in vivo mouse tail amputation model, as well as in in vitro coagulation tests. …”
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Effect of 3-hydrazinylquinoxaline-2-thiol hydrogel on skin wound healing process in diabetic rats by Jehan Barakat Alamre, Huda Alkreathy, Ahmed S. Ali, Abdelbagi Alfadil, Sahar S. Alghamdi

“…Unfortunately, the current treatment has not resulted in consistently lower amputation rates. Quinoxalines are heterocyclic compounds with multiple important pharmacological properties. …”
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Low Infection Rate after Tumor Hip Arthroplasty for Metastatic Bone Disease in a Cohort Treated with Extended Antibiotic Prophylaxis by Werner H. Hettwer, Peter Frederik Horstmann, Thea Bechmann Hovgaard, Tomas Andreas Grum-Scwensen, Michael M. Petersen

“…The overall infection rate was 3.6% (4/111 implants), infection free survival was 96% at 2 years, and the risk of amputation associated with infection was 25% (1/4 patients). …”
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The Effect of Combination Foot Massage and Active Range of Motion (ROM) on Foot Sensitivity among Patients with Type 2 Diabetic Mellitus by I Made Cahyadi Agastiya, Ni Ketut Romani, I Made Artana

“…This increases the risk of diabetic foot ulcers, causing the patient to not feel any injuries to the legs, even to amputation. Therefore, handling the proper treatment to prevent these complications is necessary, one of which is using foot massage and active ROM. …”
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Suppurative Flexor Tenosynovitis: A Case Report by Pramono Ari Wibowo, M.D., Arham Adnani

“…Postoperative results were good, with no signs of complications such as spread of infection, tendon necrosis, osteomyelitis, or indications for amputation. Discussion: The treatment for suppurative flexor tenosynovitis involves a combination of antibiotics and surgery. …”
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Preventive interventions for diabetic foot ulcer adopted in different healthcare settings: A scoping review protocol. by Açucena Leal de Araújo, Francisca Diana da Silva Negreiros, Raquel Sampaio Florêncio, Thiago Dos Santos Garces, Virna Ribeiro Feitosa Cestari, Samuel Miranda Mattos, Samara Jesus Sena Marques, Francisca Eridan Fonteles Albuquerque, Wánderson Cássio Oliveira Araújo, Vanessa de Brito Poveda, Thereza Maria Magalhães Moreira

“…<h4>Background</h4>Diabetic foot ulcers are challenging to heal, increase the risk of lower extremity amputation, and place a significant burden on patients, families, and healthcare systems. …”
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Trends in diabetes mellitus and related costs among hospital admissions in Switzerland, 2012–2020 by Hassan Abu Obaid, Pedro Marques-Vidal

“…Compared to non-DM hospitalizations, all types of DM had a higher likelihood of lower limb amputation; hospitalizations for T1DM had a higher likelihood of ICU admission: odds ratio and 95% CI: 3.38 (3.19–3.59), while T2DM had higher LOS: 5.5 ± 1.0 vs. 5.1 ± 1.0 days, and all DM types had a lower odds of in-hospital mortality. …”
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Rituximab Efficacy during a Refractory Polyarteritis Nodosa Flare by Emmanuel Ribeiro, Thomas Cressend, Pierre Duffau, Marieke Grenouillet-Delacre, Marie Rouanet-Larivière, Anne Vital, Maïté Longy-Boursier, Patrick Mercié

“…Systemic vasculitis relapses are followed to accelerated atherosclerosis: severe ischemic lesions led to amputation of lower limbs. Remission of refractory PAN is obtained with rituximab. …”
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Autologous Stem Cell Therapy in Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Houlong Luo, Yusheng Zhang, Qinghui Wang, Chenhui Zhou, Daohua Xu

“…Meta-analysis showed that cell therapy significantly increased the probability of ulcer healing (RR = 1.73, 95% CI = 1.45–2.06), angiogenesis (RR = 5.91, 95% CI = 2.49–14.02), and reduced the amputation rates (RR = 0.59, 95% CI = 0.46–0.76). Ankle-brachial index (ABI) (MD = 0.13, 95% CI = 0.11–0.15), TcO2 (MD = 12.22, 95% CI = 5.03–19.41), and pain-free walking distance (MD = 144.84, 95% CI = 53.03–236.66) were significantly better in the cell therapy group than in the control group (P<0.01). …”
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Outcome of Limb-sparing Surgery with Custom Mega Endoprosthesis Reconstruction for Bone Tumors in a Tertiary Care Center—10-year Study: Where Do We Stand? by Subbiah Shanmugam, Pravenkumar R Ramaswami

“…After re-surgery, either a second limb-sparing procedure or amputation, 49 patients (89.1%) retained their limb. …”
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A Meta-analysis: Effect of Stem Cells Transplantation on Rehabilitation of Diabetes Mellitus with Limb Ischemia by Yongjin LIU, Bo DU, Bowei HUANG, Suping HUANG

“…Compared with the control group, stem cells therapy had positive effect on the levels of ABI [WMD=0.14, 95%<italic>CI</italic> (0.10, 0.19), <italic>P</italic>&lt;0.000 01], the score of rest pain [WMD=-1.52, 95%<italic>CI</italic> (-1.84, -1.21), <italic>P</italic>&lt;0.000 01] was reduced significantly, the rate of ulcer healing [<italic>RR</italic>=2.21, 95%<italic>CI</italic> (1.54, 3.16), <italic>P</italic>&lt;0.000 1] was increased, the rate of new collateral vesse [<italic>RR</italic>=3.12, 95%<italic>CI</italic> (1.65, 5.89), <italic>P</italic>=0.000 5] was increased, and the rate of amputation [<italic>RR</italic>=0.12, 95%<italic>CI</italic> (0.02, 0.59), <italic>P</italic>=0.010] was reduced.Conclusion:Existing evidence suggested that stem cells therapy is effective on the rehabilitation of diabetes mellitus with limb ischemia to some degree. …”
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Does Melanoma Begin in a Melanocyte Stem Cell? by James D. Hoerter, Patrick Bradley, Alexandria Casillas, Danielle Chambers, Brandon Weiswasser, Lauren Clements, Sarah Gilbert, Albert Jiao

“…Zebrafish have a robust regenerative capability, permitting the study of how MSCs are regulated and recruited at specific times and places to generate the pigment pattern following fin amputation or melanocyte ablation. They can be used to determine the effects of environmental radiation on the proliferation, survival, repair, and differentiation of MSCs. …”
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Distal Femur Allograft Prosthetic Composite Reconstruction for Short Proximal Femur Segments following Tumor Resection by Bryan S. Moon, Nathan F. Gilbert, Christopher P. Cannon, Patrick P. Lin, Valerae O. Lewis

“…One pt (8%) had an amputation and one pt (8%) died prior to union. Average time to union was 19 months. …”
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&#039;I cut toenails with scissors and trim it with sand paper&#039;. Patients&rsquo; perspectives on diabetic foot complications by Suliana Saverio, Masoud Mohammadnezhad, Filimone Raikanikoda

“…This will help guide patients to make life-altering decisions that can help reduce the rate of diabetes related lower limb amputations, which are easily preventable. …”
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Patients Undergoing Subacute Physical Rehabilitation following an Acute Hospital Admission Demonstrated Improvement in Cognitive Functional Task Independence by Steven M. McPhail, Paul N. Varghese, Suzanne S. Kuys

“…Consecutive rehabilitation admissions (n=814) following acute hospitalization (study criteria excluded orthopaedic, neurological, or amputation admissions). Intervention. Usual rehabilitation care. …”
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Domestic Horse Bite: An Unusual Etiology of Crush Injury of the Fourth Finger—How to Manage? by Naoufal Elghoul, Youssef Jalal, Ayoub Bouya, Ali Zine, Abdeloihab Jaafar

“…An excisional debridement of devitalized tissue with copious irrigation was performed, and the finger regularized at the level of traumatic amputation with tendon striping followed by coverage of the bone by the radial digital flap with careful clinical and biological monitoring after the surgery. …”
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