Posterior AD-Type Pathology: Cognitive Subtypes Emerging from a Cluster Analysis by Antonella Cappa, Nicoletta Ciccarelli, Eleonora Baldonero, Marialuisa Martelli, Maria Caterina Silveri

“…“Posterior shift” of the neuropathological changes of Alzheimer's disease (AD) produces a syndrome (posterior cortical atrophy) (PCA) dominated by high-level visual deficits. …”
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A multidimensional study for design of phytochemical profiling, antioxidant potential, and enzyme inhibition effects of ışgın (Rheum telianum) as an edible plant by Ahmet Zafer Tel, Kubra Aslan, Mustafa Abdullah Yılmaz, İlhami Gulcin

“…The inhibition effects of both leaves and the seeds of the R. telianum extracts on acetylcholinesterase and butyrylcholinesterase, α-glycosidase and human carbonic anhydrases II isoenzyme enzymes, which associated with some global diseases including Alzheimer's disease, type-2 diabetes mellitus and glaucoma were determined. …”
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Multicomponent reactions driving the discovery and optimization of agents targeting central nervous system pathologies by Lucía Campos-Prieto, Aitor García-Rey, Eddy Sotelo, Ana Mallo-Abreu

“…In this review, we focus on central nervous system (CNS) disorders, particularly Alzheimer's disease, Parkinson's disease, schizophrenia, depression, and epilepsy, where MCRs have contributed to the development of promising ligands in recent years. …”
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Cerebrospinal Fluid Biomarkers and Prediction of Conversion in Patients with Mild Cognitive Impairment: 4-Year Follow-Up in a Routine Clinical Setting by Alessia Lanari, Lucilla Parnetti

“…Several investigations have shown the usefulness of cerebrospinal fluid (CSF) biomarkers (Aβ42, total tau [T-tau], and phosphorylated tau [P-tau]) in predicting the progression to Alzheimer's disease (AD). We report a 4-year follow-up of MCI patients who underwent CSF evaluation for biomarker assessment, in order to further evaluate the usefulness of CSF analysis in predicting the conversion to dementia in a routine clinical setting. …”
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CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization. by Gowtham A Rao, Azza Shoaibi, Rupa Makadia, Jill Hardin, Joel Swerdel, James Weaver, Erica A Voss, Mitchell M Conover, Stephen Fortin, Anthony G Sena, Chris Knoll, Nigel Hughes, James P Gilbert, Clair Blacketer, Alan Andryc, Frank DeFalco, Anthony Molinaro, Jenna Reps, Martijn J Schuemie, Patrick B Ryan

“…We test our framework by evaluating one PA for systemic lupus erythematosus (SLE) and two PAs for Alzheimer's disease (AD) across 10 different observational data sources.…”
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Dietary Fatty Acids and Predementia Syndromes by Vincenzo Solfrizzi, Vincenza Frisardi, Cristiano Capurso, Alessia D' Introno, Anna M. Colacicco, Gianluigi Vendemiale, Antonio Capurso, Francesco Panza

“…However, recent findings from clinical trials with n-3 PUFA supplementation showed efficacy on depressive symptoms in non–Vapolipoprotein E (APOE) ε4 carriers, and on cognitive symptoms only in very mild Alzheimer's disease (AD) subgroups, MCI patients, and cognitively unimpaired non-APOE ε4 carriers. …”
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C/EBPβ in Alzheimer’s disease: An integrative regulator of pathological mechanisms by Xiaoting Luo, Junyi Liang, Xue Lei, Fengqi Sun, Minghai Gong, Bin Liu, Zhongguang Zhou

“…Alzheimer's disease (AD) stands as one of the most prevalent neurodegenerative disorders, characterized by a progressive decline in cognitive function, neuroinflammation, amyloid-beta (Aβ) plaques, and neurofibrillary tangles (NFTs). …”
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Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation by Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia

“…This approach might be helpful to understand the selectivity of the given drug molecule in the treatment of Alzheimer's disease. The study provides evidence for consideration of C28H34N2O6 as a valuable small ligand molecule in treatment and prevention of AD associated disorders and further in vitro and in vivo investigations may prove its therapeutic potential.…”
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Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review by Feixuan Wang, Jingqiong Wan, Yangzhen Liao, Shangyu Liu, Yuan Wei, Zhen Ouyang

“…Furthermore, they reduce neurotoxicity, alleviate brain injury and neuropathy, and prevent neurodegenerative conditions including stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease in humans and/or rodents. …”
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Classifying Dementia Using Local Binary Patterns from Different Regions in Magnetic Resonance Images by Ketil Oppedal, Trygve Eftestøl, Kjersti Engan, Mona K. Beyer, Dag Aarsland

“…We explored the use of 2D local binary pattern (LBP) extracted from FLAIR and T1 MR images of the brain combined with a Random Forest classifier in an attempt to discern patients with Alzheimer's disease (AD), Lewy body dementia (LBD), and normal controls (NC). …”
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Applications of Ultrasonic Brain Imaging and Transcranial Ultrasound Therapy in Brain Injury Rehabilitation by WU Yi

“…High intensity focused ultrasound (HIFU) and low intensity focused ultrasound (LIFU) use the thermal and mechanical effects respectively to perform tissue ablation, blood-brain barrier opening, drug targeted delivery, ultrasound-assisted catheter-directed thrombolysis and neuromodulation, and can be applied to the treatment of brain tumors, brain trauma, stroke, Parkinson's disease, Alzheimer's disease, epilepsy, depression and other neurological diseases and mental diseases. …”
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Superfoods and their impact on brain health: a systematic review by Raghupathi Niranjan Kumar, Haja Nazeer Ahamed

“…Abstract Aim of the study This review examines the pharmacology and clinical applications of superfoods like Crocus sativus, Murraya koenigii, Phoenix dactylifera, Punica granatum, Ficus carica, and Beta vulgaris on mental health, anxiety, depression, schizophrenia, Alzheimer's disease, cognitive decline, psychosis, Parkinson's disease, and stroke. …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc receptor complexes that contain an immunoreceptor tyrosine-based activation motif (ITAM). …”
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A Walk-In Screening of Dementia in the General Population in Taiwan by Chun-Hung Chen, Ling-Chun Wang, Tzu-Chiao Ma, Yuan-Han Yang

“…Alzheimer's disease (AD) has increased in its prevalence due to the increasing aged population. …”
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The Impact of Care Upon Alzheimer Patient’s Family Caregiver in Sulaimani City by Farida Abdulqadir Tahir

“…Rotated Component Matrix was used to get the level of effectiveness by a series of components according to the important effects of the variables on Alzheimer disease. The researcher found that the financial burden has taken the first order, followed by psychological and then a social burden. …”
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Penerapan Dynamic Neuromuscular Stabilization Dalam Meningkatkan Gerak Dan Fungsi Tubuh–Sebuah Kajian Pustaka by Made Hendra Satria Nugraha, Ayu Riesky

“…Penerapan DNS bermanfaat dalam meningkatkan gerak dan fungsi tubuh pada beberapa populasi, seperti: Alzheimer disease, lanjut usia fungsional, forward head posture, retardasi mental, multiple sclerosis, low back pain, poor posture, atlet flatwater kayakers, dan atlet race walkers. …”
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Association of education level with mortality in United States - A cross-sectional study by Weihong Chang, Qingping Zeng, Boda Zhou

“…Higher EL was associated with reduction in male, while a risk factor in female for Alzheimer Disease, Influenza and Pneumonia Mortality. Higher EL was associated with mortality reduction in <65 subgroup, while a risk factor in ≥65 for Accidents Mortality. …”
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MRgFUS subthalamotomy in Parkinson’s disease: an approach aimed at minimizing Lesion Volume by Marina Campins-Romeu, Rebeca Conde-Sardón, Isabel Sastre-Bataller, Carlos Morata-Martínez, Mireya Losada-López, José Luís León-Guijarro, Luis Raga-Rodríguez, Julia Pérez-García, Antonio Gutiérrez-Martín, Andrés M. Lozano, Raquel Baviera-Muñoz, Irene Martínez-Torres

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Weight trajectories in aging humanized APOE mice with translational validity to human Alzheimer's risk population: A retrospective analysis. by Francesca Vitali, Jean-Paul Wiegand, Lillian Parker-Halstead, Allan Tucker, Roberta Diaz Brinton

“…Translational validity of mouse models of Alzheimer's disease (AD) is variable. Because change in weight is a well-documented precursor of AD, we investigated whether diversity of human AD risk weight phenotypes was evident in a longitudinally characterized cohort of 1,196 female and male humanized APOE (hAPOE) mice, monitored up to 28 months of age which is equivalent to 81 human years. …”
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Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations by Nelly Joseph-Mathurin, Olene Dorieux, Audrey Kraska, Anne Bertrand, Mathieu Santin, Nadine El Tannir El Tayara, Marc Dhenain

“…It leads in many cases to neurodegenerative diseases such as Alzheimer disease (AD). Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. …”
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