Neuropsychiatric symptoms in Alzheimer’s disease by J. Vegytė, R. Podėnė, E. Dlugauskas, A. Vaitkevičius

“…Neuropsychiatric symptoms worsen everyday activities, quality of life, and ability to socialise of people with Alzheimer's disease, making the diagnosis and treatment of these symptoms increasingly important. …”
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Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes by Masafumi Ihara, Hidekazu Tomimoto

“…Vascular cognitive impairment is the second most common type of dementia after Alzheimer's disease and is frequently responsible for the cognitive decline of the elderly. …”
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The role of the neurovascular unit in vascular cognitive impairment: Current evidence and future perspectives by Zhidong He, Jing Sun

“…It is the second most common type of cognitive impairment after Alzheimer's disease. The pathogenesis of VCI is complex, and neurovascular unit destruction is one of its important mechanisms. …”
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Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications by Hugo Felix Perini, Beatriz Sodré Matos, Carlo José Freire de Oliveira, Marcos Vinicius da Silva

“…Biomimetic nanocarriers demonstrate significant advancements in drug delivery systems against cancer therapy, Alzheimer's disease, autoimmune diseases, and viral infections such as COVID-19. …”
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Clinical Interaction between Brain and Kidney in Small Vessel Disease by Masaki Mogi, Masatsugu Horiuchi

“…Recently, changes in the vascular system of the brain have been shown to contribute to the onset and progression of cognitive impairment, not only vascular dementia but also Alzheimer's disease. Patients with CKD are also reported to have higher risk of impaired cognitive function in the future compared with non-CKD subjects. …”
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Cross-Talk between Apolipoprotein E and Cytokines by Hongliang Zhang, Li-Min Wu, Jiang Wu

“…Despite its importance in lipid transport and atherosclerosis pathogenesis, apoE is associated with neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson disease, and autoimmune disorders such as multiple sclerosis and psoriasis. …”
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Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein. by James W McCormick, Lauren McCormick, Gang Chen, Pia D Vogel, John G Wise

“…P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer's disease (AD). However, previous studies on the ability of P-gp to directly transport the Alzheimer's associated amyloid-β (Aβ) protein have produced contradictory results. …”
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Storage and Processing Working Memory Functions in Alzheimer-Type Dementia by T. Vecchi, V. Saveriano, L. Paciaroni

“…In the present study, we have adapted a procedure used to investigate age-related memory modifications, involving both verbal and visuo-spatial material in tasks tapping passive and active processes, to investigate the deterioration associated with Alzheimer's disease. A group of Alzheimer patients in the early stages of the disease were matched to a control group of healthy elderly. …”
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Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…The primary neuropathological diagnosis was Alzheimer's Disease Neuropathologic Change (ADNC), present predominantly in intermediate to severe forms. …”
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EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…This review explores the therapeutic potential of rosemary in alleviating nervous system disorders such as Alzheimer's disease (AD), major depressive disorder (MDD), epilepsy, Parkinson's disease (PD), addiction, and attention-deficit hyperactivity disorder (ADHD). …”
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A Comparative Interaction between Copper Ions with Alzheimer's β Amyloid Peptide and Human Serum Albumin by G. Rezaei Behbehani, L. Barzegar, M. Mohebbian, A. A. Saboury

“…Complexes between Aβ(1–16) and copper ions have been proposed to be an aberrant interaction in the development of Alzheimer's disease, where Cu2+ is involved in Aβ(1–16) aggregation. …”
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Comparison between DSQIID total / sub-item scores and plasma p-tau elevation in adults with Down's syndrome. by Makiko Shinomoto, Chisen Takeuchi, Harutsugu Tatebe, Fukiko Kitani-Morii, Takuma Ohmichi, Yuzo Fujino, Kanako Menjo, Naoto Terada, Miho Osako, Yoko Mochizuki, Satoshi Teramukai, Takahiko Tokuda, Toshiki Mizuno, Takashi Kasai

“…However, whether this questionnaire reflects the neuropsychiatric signs of biomarker-confirmed Alzheimer's disease in DS (DS-AD) remains unknown. To address this issue, we compared the plasma phosphorylated tau (P181tau: p-tau) level of a representative AD biomarker with the total score and each sub-score of the DSQIID. …”
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Insulin in Central Nervous System: More than Just a Peripheral Hormone by Ana I. Duarte, Paula I. Moreira, Catarina R. Oliveira

“…More interestingly, insulin has been also faced as the potential missing link between diabetes and aging in CNS, with Alzheimer's disease (AD) considered as the “brain-type diabetes.” …”
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DeepWei-Cu: A Deep Weibull Network for Cure Fraction Models by Ola Abuelamayem

“…Methods: In this paper, we introduce a novel neural network based on mixture cure fraction Weibull loss function. Results: Alzheimer disease dataset as long as synthetic dataset are used to study the efficiency of the model. …”
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Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reacti... by Nikolaus Berndt, Sascha Bulik, Hermann-Georg Holzhütter

“…Reduced activity of brain α-ketoglutarate dehydrogenase complex (KGDHC) occurs in a number of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. In order to quantify the relation between diminished KGDHC activity and the mitochondrial ATP generation, redox state, transmembrane potential, and generation of reactive oxygen species (ROS) by the respiratory chain (RC), we developed a detailed kinetic model. …”
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Spines, Plasticity, and Cognition in Alzheimer's Model Mice by Tara Spires-Jones, Shira Knafo

“…The pathological hallmarks of Alzheimer's disease (AD)—widespread synaptic and neuronal loss and the pathological accumulation of amyloid-beta peptide (Aβ) in senile plaques, as well as hyperphosphorylated tau in neurofibrillary tangles—have been known for many decades, but the links between AD pathology and dementia and effective therapeutic strategies remain elusive. …”
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Application of the Prevention of Disease Concent in Traditional Chinese Medicine in Acupuncture Rehabilitation Treatment of Chronic Diseases： Take Vascular Dementia as an Example by LIU Cunzhi

“…Acupuncture and moxibustion has a long history and plays an important role in the preventive treatment of Alzheimer's disease (AD), vascular dementia (VD) and other senile diseases. …”
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Aduhelm, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer’s Disease: A comprehensive review by Hannah W. Haddad, Garett W. Malone, Nicholas J. Comardelle, Arielle E. Degueure, Salomon Poliwoda, Rachel J. Kaye, Kevin S. Murnane, Adam M Kaye, Alan D. Kaye

“…Alzheimer's disease (AD) is the most common form of dementia affecting millions of individuals, including family members who often take on the role of caregivers. …”
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Examining vaccination-related adverse events in frequent neurodegenerative diseases by Shabnam Sodagari, Nassim Sodagari

“…This study investigates adverse events following vaccination in patients with four neurodegenerative diseases: Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, Multiple Sclerosis (MS), and Parkinson's disease. …”
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Specificity of Cognitive Impairment in Neurological Disease: A Methodological Critique of Parkinson’s Disease by H. J. Sagar

“…Sometimes, a relationship has been established between certain cognitive deficits and particular neurochemical deficits which has led to the notion of specific drug treatment, e.g. cholinergic deficits and memory failure in Alzheimer's disease. However, these conclusions are often potentially flawed by methodological inadequacies. …”
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