Advancing diagnosis and treatment for human African trypanosomiasis in Nigeria: challenges and future directions by Kelly Zongo, Rolayo Toyin Emmanuel

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Towards the sustainable elimination of gambiense human African trypanosomiasis in Côte d'Ivoire using an integrated approach. by Dramane Kaba, Mathurin Koffi, Lingué Kouakou, Emmanuel Kouassi N'Gouan, Vincent Djohan, Fabrice Courtin, Martial Kassi N'Djetchi, Bamoro Coulibaly, Guy Pacôme Adingra, Djakaridja Berté, Bi Tra Dieudonné Ta, Minayégninrin Koné, Barkissa Mélika Traoré, Samuel A Sutherland, Ronald E Crump, Ching-I Huang, Jason Madan, Paul R Bessell, Antoine Barreaux, Philippe Solano, Emily H Crowley, Kat S Rock, Vincent Jamonneau

“…<h4>Background</h4>Human African trypanosomiasis is a parasitic disease caused by trypanosomes among which Trypanosoma brucei gambiense is responsible for a chronic form (gHAT) in West and Central Africa. …”
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Health economic evaluation of strategies to eliminate gambiense human African trypanosomiasis in the Mandoul disease focus of Chad. by Marina Antillon, Ching-I Huang, Samuel A Sutherland, Ronald E Crump, Paul R Bessell, Alexandra P M Shaw, Iñaki Tirados, Albert Picado, Sylvain Biéler, Paul E Brown, Philippe Solano, Severin Mbainda, Justin Darnas, Xia Wang-Steverding, Emily H Crowley, Mallaye Peka, Fabrizio Tediosi, Kat S Rock

“…Human African trypanosomiasis, caused by the gambiense subspecies of Trypanosoma brucei (gHAT), is a deadly parasitic disease transmitted by tsetse. …”
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Conducting active screening for human African trypanosomiasis with rapid diagnostic tests: The Guinean experience (2016-2021). by Oumou Camara, Justin Windingoudi Kaboré, Aïssata Soumah, Mamadou Leno, Mohamed Sam Bangoura, Dominique N'Diaye, Adrien Marie Gaston Belem, Sylvain Biéler, Mamadou Camara, Jean-Mathieu Bart, Brice Rotureau, Bruno Bucheton

“…Strategies to detect Human African Trypanosomiasis (HAT) cases rely on serological screening of populations exposed to trypanosomes. …”
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A modelling assessment of short- and medium-term risks of programme interruptions for gambiense human African trypanosomiasis in the DRC. by Ching-I Huang, Ronald E Crump, Emily H Crowley, Andrew Hope, Paul R Bessell, Chansy Shampa, Erick Mwamba Miaka, Kat S Rock

“…Gambiense human African trypanosomiasis (gHAT) is a deadly vector-borne, neglected tropical disease found in West and Central Africa targeted for elimination of transmission (EoT) by 2030. …”
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Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance by Keneth Iceland, Kasozi, Ewan Thomas, MacLeod, Charles, Waiswa, Michael, Mahero, Ibrahim, Ntulume, Susan Christina, Welburn

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Identification des Villages à Risque (IVR) : pour un état des lieux de la Trypanosomiase Humaine Africaine au Niger by Jérémi Rouamba, Adamou Salissou, Hassane Sakandé, Vincent Jamonneau, Fabrice Courtin

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Is the elimination of ‘sleeping sickness’ affordable? Who will pay the price? Assessing the financial burden for the elimination of human African trypanosomiasis Trypanosoma brucei gambiense in sub-Saharan Africa by C Simone Sutherland, Fabrizio Tediosi

“…It is hoped that elimination of human African trypanosomiasis (HAT) Trypanosoma brucei gambiense (Tbg) would assist in this goal, but the financial costs are still unknown. …”
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Prevalence and attributable health burdens of vector-borne parasitic infectious diseases of poverty, 1990–2021: findings from the Global Burden of Disease Study 2021 by Yin-Shan Zhu, Zhi-Shan Sun, Jin-Xin Zheng, Shun-Xian Zhang, Jing-Xian Yin, Han-Qing Zhao, Hai-Mo Shen, Gad Baneth, Jun-Hu Chen, Kokouvi Kassegne

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Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a... by Kagbadouno, Moise S, Séré, Modou, Ségard, Adeline, Camara, Abdoulaye Dansy, Camara, Mamadou, Bucheton, Bruno, Bart, Jean-Mathieu, Courtin, Fabrice, De Meeûs, Thierry, Ravel, Sophie

Subjects: “…Tsetse flies; Human African Trypanosomiasis; Population structure; Effective population size; Vector control; Neglected Tropical Diseases…”
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Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa by Keneth Iceland, Kasozi, Zirintunda, Gerald, Ssempijja, Fred, Buyinza, Bridget, Alzahrani, Khalid J., Matama, Kevin, Nakimbugwe, Helen N., Alkazmi, Luay, Onanyang, David, Bogere, Paul, Ochieng, Juma John, Islam, Saher, Matovu, Wycliff, Nalumenya, David Paul, Batiha, Gaber El-Saber, Osuwat, Lawrence Obado, Abdelhamid, Mahmoud, Shen, Tianren, Omadang, Leonard, Welburn, Susan Christina

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Dual suppression of Glossina pallidipes using entomopathogenic fungal-based biopesticides and sterile insect technique by Fidelis L. O. Ombura, Fidelis L. O. Ombura, Adly M.M Abd-Alla, Komivi S. Akutse, Komivi S. Akutse, Steven Runo, Paul O. Mireji, Paul O. Mireji, Rosemary Bateta, Joseck E. Otiwi, Inusa J. Ajene, Fathiya M. Khamis, Fathiya M. Khamis

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Systematic Review and Meta-Analysis on Human African Trypanocide Resistance by Keneth Iceland, Kasozi, Ewan Thomas, MacLeod, Susan Christina, Welburn

Subjects: “…Human African trypanosomiasis…”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. …”
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…However, this aspect of African trypanosomiasis remains poorly understood, partially due to a lack of well-characterized and practical animal models. …”
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The current status of neglected tropical diseases in Japan: A scoping review. by Yuriko Harada, Hanako Iwashita, Taeko Moriyasu, Sachiyo Nagi, Nobuo Saito, Mariko Sugawara-Mikami, Kota Yoshioka, Rie Yotsu, Japan NTD Study Group

“…At least one laboratory offers diagnostic testing for each NTD except for dracunculiasis, human African trypanosomiasis, onchocerciasis, and yaws. No medicine is approved for treatment of Chagas disease and fascioliasis and only off-label use drugs are available for cysticercosis, opisthorchiasis, human African trypanosomiasis, onchocerciasis, schistosomiasis, and yaws. …”
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Prevalence of Trypanosoma congolense and Trypanosoma vivax in Lira District, Uganda by Aziz, Katabazi, Adamu, Almustapha Aliero, Simon Peter, Musinguzi

“…Trypanosomes are the causative agents of animal African trypanosomiasis (AAT) and human African trypanosomiasis (HAT), the former affecting domestic animals prevalent in Sub-Saharan Africa. …”
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Prevalence of Trypanosoma congolense and Trypanosoma vivax in Lira District, Uganda by Aziz, Katabazi, Adamu, Almustapha Aliero, Sarah, Gift Witto, Martin, Odoki, Simon Peter, Musinguzi

“…Trypanosomes are the causative agents of animal African trypanosomiasis (AAT) and human African trypanosomiasis (HAT), the former affecting domestic animals prevalent in Sub-Saharan Africa. …”
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African animal trypanocide resistance: A systematic review and meta-analysis by Keneth Iceland, Kasozi, Ewan, Thomas MacLeod, Susan, Christina Welburn

“…Background: African animal trypanocide resistance (AATr) continues to undermine global efforts to eliminate the transmission of African trypanosomiasis in endemic communities. The continued lack of new trypanocides has precipitated drug misuse and overuse, thus contributing to the development of the AATr phenotype. …”
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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense, and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and T. b rhodesiense are responsible for chronic and acute human African trypanosomiasis (HAT), respectively. …”
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