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TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins
Published 2025-01-01“…Modulation of TLR10 expression could have implications for the treatment of patients with severe COVID-19, in whom excessive inflammation leading to the development of acute respiratory distress syndrome (ARDS) is a key feature. However, further research is needed to fully understand the impact of modulating TLR10 expression on the antiviral response and the overall balance of the immune response during SARS-CoV-2 infection.…”
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122
The Role of Macrophages in the Pathogenesis of ALI/ARDS
Published 2018-01-01“…Despite development in the understanding of the pathogenesis of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), the underlying mechanism still needs to be elucidated. …”
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123
Medical-Surgical Nursing : assessment and management of clinical problems /
Published 2011Table of Contents: “…V. 2 -- Gastrointestinal system -- Nutritional problems -- Obesity -- Upper gastrointestinal problems -- Lower gastrointestinal problems -- Liver, pancreas, and biliary tract problems -- Urinary system -- Renal and urologic problems -- Acute kidney injury and chronic kidney disease -- Endocrine system -- Diabetes mellitus -- Endocrine problems -- Reproductive system -- Breast disorders -- Sexually transmitted diseases -- Female reproductive problems -- Male reproductive problems -- Nervous system -- Acute intracranial problems -- Stroke -- Chronic neurologic problems -- Alzheimer's disease, dementia, and delirium -- Peripheral nerve and spinal cord problems -- Musculoskeletal system -- Musculoskeletal trauma and orthopedic surgery -- Musculoskeletal problems -- Arthritis and connective tissue diseases -- Critical care -- Shock, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome -- Respiratory failure and acute respiratory distress syndrome -- Emergency, terrorism, and disaster nursing -- Appendixes A: Cardiopulmonary resuscitation and basic life support for health care providers -- Appendixes B: Nursing diagnoses -- Appendixes C: Laboratory references intervals.…”
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124
Bortezomib-Induced Bronchiolitis Obliterans Organizing Pneumonia
Published 2012-01-01“…After administering chemotherapy, the patient developed an acute respiratory distress syndrome (ARDS). A surgical pulmonary biopsy proved the existence of bronchiolitis obliterans organizing pneumonia (BOOP) lesions. …”
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125
Influenza A/H1N1 Severe Pneumonia: Novel Morphocytological Findings in Bronchoalveolar Lavage
Published 2014-01-01“…We present the results of bronchoalveolar lavage (BAL) performed in three patients with severe influenza A/H1N1 pneumonia complicated by acute respiratory distress syndrome (ARDS). Light microscopy analysis of BAL cytocentrifugates showed the presence of characteristic large, mononuclear, plasmoblastic/plasmocytoid-like cells never described before. …”
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126
Profile of Candida bloodstream infections among blood culture-positive patients at a tertiary care hospital
Published 2024-01-01“…The associated risk factors among patients with candidemia were diabetes (60%), chronic kidney disease (26.7%), acute respiratory distress syndrome (23.3%), chronic liver disease (23.3%), and cerebrovascular accident (16.7%). …”
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127
Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions
Published 2017-01-01“…Sepsis is characterized by injury of the pulmonary microvasculature and the pulmonary microvascular endothelial cells (PMVEC), leading to barrier dysfunction and acute respiratory distress syndrome (ARDS). Our recent work identified a strong correlation between PMVEC apoptosis and microvascular leak in septic mice in vivo, but the specific role of apoptosis in septic PMVEC barrier dysfunction remains unclear. …”
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128
Mechanical ventilation in patients diagnosed with COVID -19
Published 2023-07-01“…Prone position ventilation has been shown to improve oxygenation and lung mechanics in patients with acute respiratory distress syndrome.<br /><strong>Objective:</strong> to describe the characteristics of mechanical ventilation in patients diagnosed with COVID -19 at the Ambato General Hospital.…”
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129
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Published 2025-02-01“…This study leverages protein engineering to enhance ACE2’s therapeutic potential for treating conditions such as respiratory viral infections, acute respiratory distress syndrome, and diabetes. Surrogate substrates used in traditional high-throughput screening methods for peptidases often fail to accurately mimic native substrates, leading to less effective enzyme variants. …”
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130
Role of Dexmedetomidine by Improving Sleep Quality and Pain Control in Covid-19 Patients
Published 2023-04-01“… OBJECTIVE: To demonstrate the effective role of Dexmedetomidine as a sedative and analgesic agent in Covid-19 patients when used in conjunction with the established treatment of Acute Respiratory Distress Syndrome. INTRODUCTION: Covid-19 disease is a deadly contagious disease with milder symptoms to a more severe form with acute respiratory failure, septic shock leading to even death. …”
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131
Dental Mesenchymal Stem/Stromal Cells and Their Exosomes
Published 2018-01-01“…The therapeutic applicability of these cells and exosomes in dental practice, neurodegenerative diseases, and many other difficultly treatable diseases, like myocardial infarction, focal cerebral ischemia, acute lung or brain injury, acute respiratory distress syndrome, acute inflammation, and several others is concisely covered. …”
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132
Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
Published 2020-01-01“…A novel coronavirus identified in 2019 leads to a pandemic of severe acute respiratory distress syndrome with important morbidity and mortality. …”
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133
A Case of Severe Multisystem Inflammatory Syndrome in Children (MIS-C) Treated with Multiple Biologics
Published 2022-01-01“…While most have mild upper respiratory viral symptoms, some have died due to severe pneumonia, acute respiratory distress syndrome (ARDS), or coagulopathies to mention a few. …”
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134
Therapeutic Approaches in COVID-19 Patients: The Role of the Renin-Angiotensin System
Published 2022-01-01“…A few studies suggest benefits of low-dose radiation therapy (LDR) in treating acute respiratory distress syndrome in COVID-19 patients. Nonetheless, radiation therapy can stimulate inflammatory pathways, resulting in adverse effects on lung injury in these patients. …”
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135
Evaluating the Factors Affecting COVID-19 Patients’ Mortality in Arak in 2020
Published 2022-01-01“…There was a significant relationship in terms of blood pressure, age, oxygen saturation, tachycardia, tachypnea, the interval between the onset of symptoms and hospitalization, diabetes mellitus, lung disease, cardiovascular disease, history of opium abuse, C-reactive protein, white blood cell, lymphocytes, hemoglobin, creatinine elevation, elevated liver enzyme, creatine phosphokinase, lactate dehydrogenase, ferritin, D-dimer, troponin, prothrombin time, international normalized ratio, intensive care unit admission days, arrhythmia, sepsis, acute respiratory distress syndrome, acute kidney injury (AKI), and the type of antiviral and antibiotic therapy between the two groups of patients. …”
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136
Cost Analysis of Noninvasive Helmet Ventilation Compared with Use of Noninvasive Face Mask in ARDS
Published 2018-01-01“…Intensive care unit (ICU) costs have doubled since 2000, totalling 108 billion dollars per year. Acute respiratory distress syndrome (ARDS) has a prevalence of 10.4% and a 28-day mortality of 34.8%. …”
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137
Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin
Published 2012-01-01“…The acute respiratory distress syndrome (ARDS), a clinical complication of severe acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in critically ill patients. …”
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138
Bronchoalveolar Activation of Coagulation and Inhibition of Fibrinolysis during Ventilator-Associated Lung Injury
Published 2012-01-01“…Secondary analysis of a randomized controlled trial evaluating the effect of lower tidal volumes versus conventional tidal volumes in patients without acute lung injury or acute respiratory distress syndrome at the onset of mechanical ventilation. …”
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139
Endobronchial One-Way Valve Therapy Facilitates Weaning from Extracorporeal Membrane Oxygenation in a Patient with ARDS and Persistent Air Leak
Published 2018-01-01“…There are numerous reports of treatment of PAL using endobronchial valves (EBV) in respiratory stable patients, but only few reports on critically ill patients, and there is virtually no practical knowledge in the treatment of PAL in mechanically ventilated patients with acute respiratory distress syndrome (ARDS), treated with veno-venous extracorporeal membrane oxygenation (vvECMO). …”
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140
Predictive value of hematologic indices in COVID-19 disease outcomes
Published 2024-12-01“…In more severe cases it can lead to sepsis, acute respiratory distress syndrome and other organ dysfunction. …”
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