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Action potential-like modes as modulated waves in an extended soliton model for biomembranes and nerves
Published 2025-01-01“…By extending the Heimburg–Jackson soliton model for neural signals that considers the effects of higher-order nonlinearities, the dynamics of modulated waves characterizing electromechanical density pulses is described in the form of soliton-like pulse signals representing nerve impulses, well-known as action potential pulses (Appulses). The investigation is performed both analytically and numerically, where a comprehensive picture of higher-order nonlinearities effects on the generation and evolution of nerve impulses is provided. …”
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2
Modelling pacemaker oscillations in lymphatic muscle cells: lengthened action potentials by two distinct system effects
Published 2025-01-01“…While this qualitatively replicated the period of oscillations under different conditions, it did not replicate the action potential shape as it varied under those conditions, particularly as regards the extent or lack of a systolic plateau. …”
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Effect of Depth of Total Intravenous General Anesthesia on Intraoperative Electrically Evoked Compound Action Potentials in Cochlear Implantation Surgery
Published 2019-01-01“…This study aims to compare the effect of the depth of total intravenous anesthesia (TIVA) on intraoperative electrically evoked compound action potential (e-ECAP) thresholds in cochlear implant operations. …”
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4
Cordycepin Decreases Compound Action Potential Conduction of Frog Sciatic Nerve In Vitro Involving Ca2+-Dependent Mechanisms
Published 2015-01-01“…Cordycepin has been widely used in oriental countries to maintain health and improve physical performance. Compound nerve action potential (CNAP), which is critical in signal conduction in the peripheral nervous system, is necessary to regulate physical performance, including motor system physiological and pathological processes. …”
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In silico analysis of ventricular action potential with a current–voltage‐time representation: Thresholds, membrane resistance, repolarization reserve
Published 2024-11-01Subjects: “…cardiac action potential…”
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Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings
Published 2025-01-01“…Nanoelectrode Arrays (NEAs) offer a promising alternative by enabling simultaneous intracellular and extracellular action potential (iAP and eAP) recordings with high throughput. …”
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Maladaptive changes in the homeostasis of AEA-TRPV1/CB1R induces pain-related hyperactivity of nociceptors after spinal cord injury
Published 2025-01-01Subjects: Get full text
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A finite element model for biomechanical characterization of ex vivo peripheral nerve dysfunction during stretch
Published 2024-11-01Subjects: Get full text
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Preliminary evaluation of the FastCAP for users of the Nurotron cochlear implant
Published 2025-01-01Subjects: “…electrically evoked compound action potential…”
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10
Functional differentiation of human dental pulp stem cells into neuron-like cells exhibiting electrophysiological activity
Published 2025-01-01Subjects: Get full text
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11
Mathematical model of the atrioventricular nodal double response tachycardia and double-fire pathology
Published 2016-07-01Subjects: Get full text
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12
Ion channel traffic jams: the significance of trafficking deficiency in long QT syndrome
Published 2025-01-01“…Ion channel variants and many drugs can alter the cardiac action potential and lead to arrhythmias by interfering with mechanisms like ion channel synthesis, trafficking, gating, permeation, and recycling. …”
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Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation
Published 2025-01-01“…Mutant microglia exhibited increased activation and induced apoptosis in hippocampal neurons, leading to higher action potential frequency and excitatory synaptic marker expression. …”
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Electrophysiological Predictors of Clinical Outcome in Traumatic Neuropathies: A Multicenter Prospective Study
Published 2016-01-01“…Clinical improvement correlated with the increase of the compound muscle action potential amplitude (OR 3.76; CI 1.61–8.76), particularly in the S group (OR 7.25; CI 1.2–43.87), and with sensory nerve action potential amplitude in the NS group (OR 4.35; CI 1.14–16.69). …”
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15
Altered Left Ventricular Ion Channel Transcriptome in a High-Fat-Fed Rat Model of Obesity: Insight into Obesity-Induced Arrhythmogenesis
Published 2016-01-01“…The potential effects of the mRNA changes on the ventricular action potential and intracellular Ca2+ transient were predicted using computer modelling. …”
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Axonal excitability and conduction alterations caused by levobupivacaine in rat
Published 2017-09-01“…In order to deduce its effects on isolated nerve conduction, compound nerve action potential (CNAP) recordings were performed using the suction method over sciatic nerves of Wistar rats before and after administration of 0.05 % (1.7 mmol L−1) levobupivacaine. …”
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Cytokine Reduction in the Treatment of Joint Conditions
Published 1994-01-01“…The destructive action of cytokines such as interleukin-1, interleukin-6 and tumour necrosis factor-α can be modulated at multiple points associated either with cytokine production or with cytokine action. Potential agents for cytokine reduction include selective anti-cytokine antibodies, anticytokine receptor antibodies, cytokine receptor antagonist proteins, and soluble and chimeric cytokine receptor molecules. …”
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Single unit-derived connectivity networks in tuberous sclerosis complex reveal propensity for network hypersynchrony driven by tuber-tuber interactions
Published 2024-12-01“…We investigated patterns of single neuron action potential behaviour in 206 neurons recorded from tubers, transmantle tails of tubers and normal looking cortex in 3 children with tuberous sclerosis. …”
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Presynaptic Ionotropic Receptors Controlling and Modulating the Rules for Spike Timing-Dependent Plasticity
Published 2011-01-01“…In line with predictions made by Hebb, synapse strength can be modified depending on the millisecond timing of action potential firing (STDP). The sign of synaptic plasticity depends on the spike order of presynaptic and postsynaptic neurons. …”
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Mouse-derived Synaptosomes Trypsin Cleavage Assay to Characterize Synaptic Protein Sub-localization
Published 2025-01-01“…Upon the arrival of an action potential, neurotransmitters are released from the presynaptic site and diffuse across the synaptic cleft to bind specialized receptors at the postsynaptic terminal. …”
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