A multi-stakeholder collaborative approach to awareness, education and support needed in the haemophilia gene therapy patient journey – a report on insights from a European patient... by O’Mahony Brian, Fletcher Simon, Baarslag Manuel, Khair Kate, Breederveld Daan, Jansen Nathalie, Pembroke Luke, Pinachyan Karen, Sivasubramaniyam Sujan

“…Teach-back could help ensure appropriate levels of understanding; psychological support could aid managing expectations. Peer-to-peer learning delivered across a variety of platforms, to share experiences of gene therapy and contextualise more ‘formal’ gene therapy education, was considered invaluable.…”
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Class 3 Obesity in a Multidisciplinary Metabolic Weight Management Program: The Effect of Preexisting Type 2 Diabetes on 6-Month Weight Loss by David M. Medveczky, Raymond Kodsi, Kathryn Skelsey, Kathy Grudzinskas, Flavia Bueno, Vincent Ho, Nic Kormas, Milan K. Piya

“…However, newer weight-neutral/losing diabetes medications can aid additional weight loss. The aim of this study was to compare weight loss outcomes of patients with and without T2DM, and in patients with T2DM, to compare diabetes outcomes and change in medications at 6 months. …”
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Solid medical waste management practices and awareness in COVID-19 screening stations by S.E. Alzghoul, O.A. Smadi, T. Almomani, M.B. Alzghoul, O.M. Al-Bataineh

“…Furthermore, the results of the third module revealed that the private sector fails to successfully execute national and international procedures, with the most significant negative responses among other categories.CONCLUSION: It was concluded that Jordan's solid waste collection and disposal methods were effectively implemented, which might aid in the virus eradication. Even though most Jordanian screening stations have effectively implemented knowledge and awareness regarding solid Coronavirus disease 2019 wastes management practices, there is a need to undertake periodic training and continuous monitoring with a specific focus on the appropriate administrative and collecting processes for both technicians, and private sector stations.…”
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Understanding Loneliness in an Aging Population of San Vito de Coto Brus, Costa Rica by Nicholas Leahy, Melissa Rallo, Lillianna Pedersen, Christine Wan, Hima Konduru, Shania Bailey, Alexis Vetack, Wendel Mora, Shailvi Gupta, Carlos Faerron Guzmán

“…Investigators conducted face-to-face interviews in Spanish with the aid of translators. The primary instruments used for the present study were a content-validated version of the 11-item De Jong Gierveld Loneliness Scale and socio-demographic questions that included age, sex, address, civil status, and level of education. …”
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Effect of Respiratory Training combined with Core Stability Training for Children with Spastic Cerebral Palsy by Binong HU, Kai ZHANG, Fang QI, Chunhua WANG, Wenyin ZHOU, Kun AI, Hong ZHANG

“…Objective:To observe the effect of respiratory training combined with core stability training on motor function, balance function and daily life ability of children with spastic cerebral palsy.Methods:A total of 74 children with spastic cerebral palsy who were treated in the deparment of child rehabilitation of Xiangya fraternity rehabilitation hospital from March to December 2019, which were divided into the control group and the observation group according to the random number table, with 37 cases in each group.In the course of treatment, two cases dropped in each group, and finally 35 cases were included in each group.The control group was given core stability training on the basis of routine rehabilitation training.The routine rehabilitation training mainly included stretching training, joint range of motion training and occupational therapy, 10 minutes each time.Core stability training mainly included bypass training, sitting up training, suspension system training and Bobath ball training, 40 minutes per time.On the basis of routine rehabilitation training in the control group, the core stability training time of the observation group reduced from 40 minutes to 20 minutes each time, and then received respiratory training, 20 minutes each time.Respiratory training mainly includes abdominal respiratory training(7 min per time), chest expanding exercise training(3 min per time), respiratory aid method training(4 min per time), and anti blocking respiratory training(6 min per time).All the above items were trained twice a day, five times a week, continuous treatment for three months.Before and after treatment for three months, D and E functional domains of gross motor function measure scale-88(GMFM-88)was used to assess the gross motor function such as standing, walking, running and jumping; the Berg balance scale(BBS)was used to assess the balance function;and the Barthel index(BI)was used to assess the daily life activity ability.Results:Before treatment, there were no significant difference in the D and E functional domains scores of GMFM-88, BBS scores and BI scores between the two groups, with no statistically significant differences(<italic>P</italic>&gt;0.05).Compared with before treatment, the D and E functional domains of scores GMFM-88, BBS scores, BI scores of the both groups after treatment for three months were significantly improved, with statistically significant differences(<italic>P</italic>&lt;0.05).Compared with the control group, the D and E functional domains of scoresGMFM-88, BBS scores, BI scores in the observation group were significantly higher than those of the control group, with statistically significant differences(<italic>P</italic>&lt;0.05).Conclusion:Respiratory training combined with core stability training can significantly improve the gross motor function, balance function and daily life ability of children with spastic cerebral palsy, which is worthy of clinical promotion.…”
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A prediction nomogram for residual after negative pressure aspiration for endogenic cesarean scar ectopic pregnancy: a retrospective study by Yan Lei, Na Zhang, Yu Liu, Xin Du

“…Conclusions The model may aid in individual clinical decision-making, allowing clinicians to perform immediate postoperative assessments for patients with endogenous ectopic pregnancy in cesarean section scars treated with negative pressure suction, identify high-risk subpopulations, and select appropriate supplementary treatment in advance, making it particularly suitable for low-income areas and resource-limited primary hospitals.…”
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Molecular Epidemiological Characteristics of <i>Staphylococcus pseudintermedius</i>, <i>Staphylococcus coagulans,</i> and Coagulase-Negative Staphylococci Cultured from Clinical Ca... by Sara Horsman, Julian Zaugg, Erika Meler, Deirdre Mikkelsen, Ricardo J. Soares Magalhães, Justine S. Gibson

“…This highlights the importance of ongoing surveillance to aid in evidence-based treatment decisions and antimicrobial stewardship.…”
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Human cytomegalovirus (HCMV) trends in Sri Lanka: insights from a hospital-based seroprevalence analysis by Narapity Pathirannehalage Sunil-Chandra, Madawala Vithanage Madusha Lakmali Jayasundara, Maththe Gama Ralalage Shobha Sanjeewani Gunathilaka, Suduwa Dewage Himal Suminda

“…This study provides essential background information on HCMV infection and its impacts in diverse populations of Sri Lanka and aids in executing preventive and therapeutic measures in high-risk populations.…”
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Outcome of Newborns with Tracheoesophageal Fistula: An Experience from a Rapidly Developing Country: Room for Improvement by Amal Al-Naimi, Sara G. Hamad, Abdalla Zarroug

“…The distribution of the patients’ characteristics and postoperative complications was almost comparable to those from developed countries. This study would aid in addressing the prognostic factors and establishment of evidence-based management pathways of newborns with TEF to improve the clinical outcome in our center and other pediatric tertiary centers in developing countries.…”
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Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene. by Bonoshree Sarkar, Muhammad Safiul Alam Mondal, Taibur Rahman, Md Ismail Hosen, Atiqur Rahman

“…Structural analysis with normal and mutant residues of the protein harboring these disease-associated functional SNPs was conducted using TM-align and SWIS MODEL, with visualization aided by PyMOL and the BIOVINA Discovery Studio Visualizer. …”
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A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ali Hussain Ansari, Saqib Hussain Ansari, Mubarak Jabeen Salman, Muhammad Usman Hussain Ansari, Rawshan Jabeen

“…Collaborative efforts with international partners and drawing insights from successful strategies in countries with similar β-TM burdens can aid in mitigating the overall impact of β-TM in Pakistan and improving the quality of life of the affected individuals.…”
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Survival Status and Predictors of Mortality among Multidrug-Resistant Tuberculosis Patients in Saint Peter’s Specialized Hospital, Addis Ababa, Ethiopia by Mikyas Arega Muluneh, Abayneh Birlie Zeru, Behailu Tariku Derseh, Abebaw Molla Kebede

“…So, prevention and controlling of anemia, HIV/AIDS, and clinical complications will reduce the mortality of MDR-TB patients.…”
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Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States by Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé

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Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis by Yanan He, Jixin Li, Yanjun Qu, Liyuan Sun, Xibo Zhao, Han Wu, Guangmei Zhang

“…Therefore, there is an urgent need to identify reliable biomarkers for early detection and accurate diagnosis to predict clinical outcomes and aid in the early intervention of endometriosis. …”
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The study of the homogeneity management of nursing quality within members of the tightly-knit medical alliance (紧密型医联体内护理同质化管理与效果) by ZHANG Yuhong (张育红), YAN Meiqiong (颜美琼)

“…Results The grading nursing care , ward management, first aid items, disinfection-isolation and nursing documents after the implementation of homogeneity management were significantly better than pre-homogeneity management (P<0. 01), and so did the outcomes of assessment on clinical nursing skills (P<0. 01). …”
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Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review by P. Maurice, J. McCallion, M. Fitzgibbon, J. N. Barthelmes, W. Karmous, E. J. Hardy, S. A. Mitchell, C. R. Mitchell, J. Lee, W. Noel, Andras Borsi, J. M. Jouannic

“…While the limited evidence indicates that HDFN does confer a significant burden on patients, the review identifies the need for further well-powered and representative observational studies using well-defined outcome measures to aid a greater understanding of the burden and experience of HDFN. …”
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Development and Validation of a Predictive Model Based on Serum Silent Information Regulator 6 Levels in Chinese Older Adult Patients: Cross-Sectional Descriptive Study by Yuzi You, Wei Liang, Yajie Zhao

“…The nomogram for CAD outcome prediction in older adult patients with angina pectoris may aid in clinical trial design and personalized clinical decision-making, particularly in institutions where SIRT6 is being explored as a biomarker for aging or cardiovascular health.…”
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Migration of Health Workers and Its Impacts on the Nigerian Health Care Sector: Protocol for a Scoping Review by David Omiyi, Ebenezer Arubuola, Marcus Chilaka, Md Shafiqur Rahman Jabin

“…Furthermore, the results will aid in recognizing deficiencies in the existing literature; this will offer a defined path for specific policy measures and methods to retain health care workers effectively and thus support the sustainability of health care systems. …”
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Identifying the Latitude and Longitude of ATMs in ATM Networks by Niloofar Haghjoo, Mohammad rahmati, Ali Zare Mirakabad

“…Objective The geographical positioning of Automated Teller Machines (ATMs) is a pivotal data point that significantly aids in the analytical process and decision-making for a multitude of critical banking and economic determinations. …”
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Preliminary ultrasonography study of the pancreas in the dromedary camel (Camelus dromedarius) by El Hassania Lakhel, Khalid El Allali, Mohamed Rachid Achaâban, Rahma Azrib

“…The pancreatic major duct was seen as an anechoic circle with a hyperechoic wall, with a maximum diameter of 1 cm, and the left lobe scanned beneath the cranial extremity of the spleen; its ultrasonographic pattern showed an irregular hypoechoic band with a mean thickness of 2.32 ± 0.32 cm (n = 14) in young camels and 3.08 ± 0.52 cm (n = 8) in the adults, including a small splenic vein.ConclusionUltrasonography combined with Doppler techniques provides valuable information on pancreatic health, blood flow, and tissue perfusion, aiding early detection of pancreatic diseases and, consequently, minimizing economic losses in camel husbandry.…”
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