A Novel Oxidative Stress Mediator in Acute Appendicitis: Thiol/Disulphide Homeostasis by Sefa Ozyazici, Faruk Karateke, Umit Turan, Adnan Kuvvetli, Huseyin Kilavuz, Burak Karakaya, Pınar Ozaltun, Murat Alısık, Ozcan Erel

“…This is the first study examining the thiol/disulphide homeostasis as a diagnostic aid in AA and establishing thiol/disulphide homeostatis balance shifted towards the disulphide formation due to thiol oxidation. …”
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Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments by Anne-Cécile Chiollaz, Virginie Pouillard, Michelle Seiler, Céline Habre, Fabrizio Romano, Céline Ritter Schenck, Fabian Spigariol, Christian Korff, Fabienne Maréchal, Verena Wyss, Lyssia Gruaz, Joan Montaner, Jean-Charles Sanchez, Sergio Manzano

“…ObjectiveBlood-biomarkers have the potential to aid clinicians in pediatric emergency departments (PED) in managing children with mild traumatic brain injury (mTBI) acutely. …”
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Identification of Health Needs in Ukrainian Refugees Seen in a Primary Care Facility in Tenerife, Spain by Willian-Jesús Martín-Dorta, Cristo-Manuel Marrero-González, Eva-Lourdes Díaz-Hernández, Pedro-Ruymán Brito-Brito, Domingo-Ángel Fernández-Gutiérrez, Oxana-Migalievna Rebryk-De Colichón, Ana-Isabel Martín-García, Estrella Pavés-Lorenzo, María-Candelaria Rodríguez-Santos, Juan-Francisco García-Cabrera, Janet Núnez-Marrero, Alfonso-Miguel García-Hernández

“…Early provision of information about available healthcare services and protocols can facilitate access, manage expectations, and aid decision-making.…”
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A multidimensional Bayesian IRT method for discovering misconceptions from concept test data by Martin Segado, Aaron Adair, John Stewart, Yunfei Ma, Byron Drury, David Pritchard

“…While work remains to validate our findings, our hope is that future applications of this method could aid in the refinement of existing concept inventories or the development of new ones, enable the discovery of previously-unknown student misconceptions across a variety of disciplines, and—by leveraging the method's ability to quantify the prevalence of particular misconceptions—provide opportunities for targeted instruction at both the individual and classroom level.…”
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Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…However, we lack concentrated data on the characteristics of this population and the transformed SCLC to aid our insight of the biology and clinical value of NSCLC transforming with positive. …”
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Upskilling or deskilling? Measurable role of an AI-supported training for radiology residents: a lesson from the pandemic by Mattia Savardi, Alberto Signoroni, Sergio Benini, Filippo Vaccher, Matteo Alberti, Pietro Ciolli, Nunzia Di Meo, Teresa Falcone, Marco Ramanzin, Barbara Romano, Federica Sozzi, Davide Farina

“…Conclusion With this work, we gathered quantitative and qualitative evidence of the beneficial use of a high-performance AI tool that is well integrated into the diagnostic workflow as a training aid for radiology residents. Critical relevance statement Balancing educational benefits and deskilling risks is essential to exploit AI systems as effective learning tools in radiology residency programs. …”
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Impact of advanced lung cancer inflammation index on all-cause mortality among patients with heart failure: a systematic review and meta-analysis with reconstructed time-to-event d... by Ahmed Mazen Amin, Ramy Ghaly, Hossam Elbenawi, Abdelrahman Ewis, Ubaid Khan, Khaled S. M. Elshaer, Mohamed Abuelazm, Basel Abdelazeem, Brijesh Patel, Farris K. Timimi, Islam Y. Elgendy

“…These findings suggest that ALI can be used for prognostic stratification and aid clinical decision-making in HF management.…”
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Issues of diagnostics and treatment of abdominal pain at irritable bowel syndrome at outpatient stage of the healthcare by Yu. A. Kucheryavy, T. L. Lapina, M. A. Livzan, M. F. Osipenko

“…Symptomatic treatment by antispasmodic drugs is justified from the moment of referral for medical aid to outpatient department. Hyoscine butylbromide can be prescribed for relief of acute and chronic pain at any stage of diagnostic process. …”
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Platelet-Rich Plasma Improves the Wound Healing Potential of Mesenchymal Stem Cells through Paracrine and Metabolism Alterations by Barbara Hersant, Mounia Sid-Ahmed, Laura Braud, Maud Jourdan, Yasmine Baba-Amer, Jean-Paul Meningaud, Anne-Marie Rodriguez

“…In conclusion, our study strengthens that the use of PRP in combination with MSC might be a safe alternative to aid wound healing.…”
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Establishment of a rapid method for the detection of Brucella canis based on recombinase-mediated thermostable nucleic acid amplification technology by Shao-Zheng Song, Zi-Yuan Li, Yuan-Yuan Liu, Ying-Chao Wu, Kang-Ying Yu, Zhengyi He

“…ObjectiveTo establish a rapid detection method for canine brucellosis using recombinase-aided amplification (RAA) technology.MethodsThe outer membrane protein 25 gene fragment (Omp25) of Brucella canis was targeted. …”
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Mapping QTLs for early leaf spot resistance and yield component traits using an interspecific AB-QTL population in peanut by J. Gomis, J. Gomis, A. Sambou, J. R. Nguepjop, J. R. Nguepjop, J. R. Nguepjop, H. A. Tossim, M. Seye, R. Djiboune, D. Sambakhe, D. Loko, D. Loko, S. Conde, S. Conde, M. H. Alyr, D. J. Bertioli, D. J. Bertioli, S. C. M. Leal-Bertioli, S. C. M. Leal-Bertioli, J. F. Rami, J. F. Rami, A. Kane, D. Fonceka, D. Fonceka, D. Fonceka

“…This study’s findings have aided in diversifying the sources of resistance to ELS disease and other important agronomic traits, providing another compelling example of the value of peanut wild species in improving cultivated peanut.…”
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Involvement of HLADQA1*05 in Patients with Inflammatory Bowel Disease Treated with Anti-TNF Drugs by Anna Pau, Ilaria Galliano, Elisa Barnini, Maddalena Dini, Antonio Pizzol, Alice Ponte, Stefano Gambarino, Pier Luigi Calvo, Massimiliano Bergallo

“…Testing for HLA-DQA105 can aid in personalising treatment and optimising therapy to minimise immunogenicity risks.…”
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Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

“…Group 1 vtaA genes were detected in 87.5% (n = 42) of the isolates.ConclusionThis study provides comprehensive insights into the molecular mechanisms responsible for drug resistance in G. parasuis, the characteristics of molecular epidemiology, and the virulence of resistant groups. Our findings can aid in the development of G. parasuis-specific clinical breakpoints and inform strategies for managing antimicrobial resistance in swine herds.…”
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Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma by Jianwei Cui, Fanyi Zeng, Ming Tang, Ming Tang, Shiwu Yin, Shiwu Yin

“…The single-cell transcriptome and bioinformatics analyses provided insights into the mechanisms driving MVI, potentially aiding the development of targeted diagnostic and therapeutic strategies. …”
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Possibility of using a mouse SCID as a model animal to variola virus for evaluating anti-smallpox drug efficacy by K. A. Titova, Al. A. Sergeev, A. S. Kabanov, L. E. Bulychev, Ar. A. Sergeev, D. O. Galahova, A. S. Zamedyanskaya, L. N. Shishkina, O. S. Taranov, V. V. Omigov, E. L. Zavjalov, A. P. Agafonov, A. N. Sergeev

“…To fill in the gap, we have explored the possibility of using outbred immunodeficient SCID mice as a model animal for smallpox with the aid of virolo­gical, histological and electron microscopic and sta­tistical methods. …”
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A case of central diabetes insipidus after COVID-19 as a probable diagnosis of lymphocytic infundibulo-neurohypophysitis with positive anti-rabphilin-3A antibodies with review of l... by Yuka Natsuki, Yuki Nagata, Toshiki Nagasaki, Mari Morimoto, Norikazu Toi, Masafumi Kurajoh, Tomoaki Morioka, Tetsuo Shoji, Yasuo Imanishi, Naoko Iwata, Haruki Fujisawa, Atsushi Suzuki, Yoshihisa Sugimura, Masanori Emoto

“…The presence of anti-rabphilin-3A antibodies may be useful as a non-invasive diagnostic marker of LINH and potentially serve as a valuable diagnostic aid in cases of LINH associated with COVID-19.…”
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Clinical calculator based on clinicopathological characteristics predicts local recurrence and overall survival following radical resection of stage II-III colorectal cancer by Fei Huang, Ran Wei, Shiwen Mei, Tixian Xiao, Wei Zhao, Zhaoxu Zheng, Qian Liu

“…The model is expected to aid in treatment planning, such as resectability evaluation, and it can be used in postoperative surveillance (https://oldcoloncancer.shinyapps.io/dynnomapp/).…”
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Nurturing a New Industry Rooted in Geoscience: Stakeholder Insights on Minewater Thermal in Scotland by K. B. Deeming, J. Dickie, J. J. Roberts, Z. K. Shipton

“…Our findings have implications for how the geoscience community could aid the development of a minewater thermal industry. …”
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Outlining the Psychological Profile of Persistent Depression in Fibromyalgia Patients Through Personality Assessment Inventory (PAI) by Andrea Doreste, Jesus Pujol, Eva Penelo, Víctor Pérez, Laura Blanco-Hinojo, Gerard Martínez-Vilavella, Helena Pardina-Torner, Fabiola Ojeda, Jordi Monfort, Joan Deus

“…<b>Conclusions:</b> The PAI effectively identifies PDD in FM patients and detects concurrent MD episodes, aiding in better prognostic and therapeutic guidance.…”
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Functional Outcome of Mesenchymal Stem Cells Vs. Hyaluronic Acid in Knee Osteoarthritis Kellgren-Lawrence Grade I-III At 6-and 12-Months Follow-Up: A Meta-Analysis by I Gusti Ngurah Wien Aryana, Febyan, Shianita Limena

“…The highly differentiated MSC aids in tissue repair, regulation of immune response, and anti-inflammatory effect on knee osteoarthritis, including the chondrogenesis mechanism. …”
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