Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction by Cun Li, Yifei Yu, Zhixin Wan, Man Chun Chiu, Jingjing Huang, Shuxin Zhang, Xiaoxin Zhu, Qiaoshuai Lan, Yanlin Deng, Ying Zhou, Wei Xue, Ming Yue, Jian-Piao Cai, Cyril Chik-Yan Yip, Kenneth Kak-Yuen Wong, Xiaojuan Liu, Yang Yu, Lin Huang, Hin Chu, Jasper Fuk-Woo Chan, Hans Clevers, Kwok Yung Yuen, Jie Zhou

“…We demonstrate that airway organoids sustain serial virus passage with the aid of CYT387-mediated immunosuppression, whereas nasal organoids that more closely simulate the upper airway achieve this without any intervention. …”
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Advances in Biomedical Missing Data Imputation: A Survey by Miriam Barrabes, Maria Perera, Victor Novelle Moriano, Xavier Giro-I-Nieto, Daniel Mas Montserrat, Alexander G. Ioannidis

“…We outline the fundamental principles underlying each imputation technique and present a detailed analysis of their advantages and disadvantages, categorized by missing data patterns. To aid practitioners in method selection, we offer practical recommendations based on critical factors such as dataset size, data type, and missingness rate. …”
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Decoding cyanide toxicity: Integrating Quantitative Structure-Toxicity Relationships (QSTR) with species sensitivity distributions and q-RASTR modeling by Kabiruddin Khan, Ramin Abdullayev, Gopala Krishna Jillella, Varun Gopalakrishnan Nair, Mahmoud Bousily, Supratik Kar, Agnieszka Gajewicz-Skretna

“…The combined QSTR, ScSD, and q-RASTR models provide a robust framework for predicting species-specific cyanide-sensitivity, enhancing our understanding of cyanide's molecular toxicity mechanisms. This research aids environmental risk assessment and informs safer regulatory strategies. …”
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A Rare Case Presentation of Synovial Haemangioma of the Knee by Arun Karthik Ravichandran, Rajavel, Gowtham Senguttavan, Sharath Rajkumar, Saravanan Vasudevan

“…Magnetic Resonance Imaging (MRI) and arterial Doppler serve as vital diagnostic modalities that aid in the diagnosis of synovial haemangioma. Here, the authors present a case of a 15-year-old male who had experienced swelling and pain in his left knee joint for the past 13 years without receiving any prior treatment. …”
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Challenges Faced by Migrant Students in Education: A Comprehensive Analysis of Legal, Psychological, and Economic Barriers by Khasanboy Abdusamatov, Dinara Babajanova, Dilshodjon Egamberdiev, Yunus Xodjiyev, Uktamjon Tukhtaev, Nodirbek Yusupov, Sitora Shoislomova

“…Over 60% of students in the study cited issues with residency permits, affecting their eligibility for financial aid, participation in extracurricular activities, and in some cases, their ability to enroll in school at all. …”
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A generative deep neural network for pan-digestive tract cancer survival analysis by Lekai Xu, Tianjun Lan, Yiqian Huang, Liansheng Wang, Junqi Lin, Xinpeng Song, Hui Tang, Haotian Cao, Hua Chai

“…The network optimization process involves employing an integrated loss function consisting of two modules: the generative-adversarial module facilitates spatial data distribution understanding for extracting high-quality information, while the clustering module aids in identifying disease subtypes. The experiments conducted on digestive tract cancer datasets demonstrate that GDEC exhibits exceptional performance compared to other advanced methodologies and can separate different cancer molecular subtypes that possess both statistical and biological significance. …”
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A comparison of sex-specific senescence patterns in a long-lived marine mammal by Kaitlin R. Macdonald, Jay J. Rotella, William A. Link

“…These results add to our understanding of sex-specific survival rates in the species and contribute information for a long-lived, polygynous species that should aid in achieving a broader understanding of aging between sexes and across the tree of life.…”
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Prognosis of patients with breast cancer who underwent breast-conserving surgery using a 3D-printed surgical guide after neoadjuvant chemotherapy by Ah Yoon Kim, Sae Byul Lee, Tae Kyung Yoo, Ji Sun Kim, Il Yong Chung, Hee Joung Kim, Jong Won Lee, Byung Ho Son, Jae Ho Jeong, Hee Jin Lee, Nam kug Kim, BeomSeok Ko

“…Between November 2015 and October 2021, patients received BCS with the aid of a 3DP-BSG. Personalized 3DP-BSG targeted tumors by tracking changes in breast and tumor anatomy on MRI before and after NACT. 203 patients with invasive breast cancer were enrolled in the study. …”
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Global Sensitivity Analysis and Uncertainty Quantification for Background Solar Wind Using the Alfvén Wave Solar Atmosphere Model by Aniket Jivani, Nishtha Sachdeva, Zhenguang Huang, Yang Chen, Bart van derHolst, Ward Manchester, Daniel Iong, Hongfan Chen, Shasha Zou, Xun Huan, Gabor Toth

“…Sobol' indices also allow us to rank and retain only the most important parameters, which aids in the construction of smaller ensembles for the reduced‐dimension parameter space. …”
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The Role of Mathematics and Science Education in the Adult Offender Rehabilitation Process by Siphelele Mbatha, Halalisani Mngomezulu, Nonhlanhla Nduku, Onelisa Mbathu

“…The study will further aid in disseminating the unique role of offender mathematics and science education, particularly for scholars and policymakers whose focus is on offender rehabilitation in the democratic dispensation.…”
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Hydroxychloroquine and Fabry Disease: Three Case Reports Examining an Unexpected Pathologic Link and a Review of the Literature by Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes

“…We include key histologic features in images which aid in identifying and distinguishing hydroxychloroquine toxicity from mimickers. …”
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An MR Brain Images Classifier System via Particle Swarm Optimization and Kernel Support Vector Machine by Yudong Zhang, Shuihua Wang, Genlin Ji, Zhengchao Dong

“…The abnormal brain MR images consist of the following diseases: glioma, metastatic adenocarcinoma, metastatic bronchogenic carcinoma, meningioma, sarcoma, Alzheimer, Huntington, motor neuron disease, cerebral calcinosis, Pick’s disease, Alzheimer plus visual agnosia, multiple sclerosis, AIDS dementia, Lyme encephalopathy, herpes encephalitis, Creutzfeld-Jakob disease, and cerebral toxoplasmosis. …”
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Strategies for strengthening cervical cancer screening programmes in Gwanda district, Zimbabwe: a qualitative study by Fennie Mantula, Yoesrie Toefy, Vikash Sewram

“…Data were analysed thematically with the aid of the Web Atlas.ti software. Results Key findings suggest that women’s willingness to be screened, on-going awareness campaigns and an increasing number of screening sites and nurses trained in screening procedures promote the uptake of screening. …”
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Neuropharmacological profile of new thiazepinone and thiazolidinone compounds designed by virtual screening by Juan Sebastian Carrero-Sandoval, Paola Andrea Cuervo-Prado, Fabian Orozco-Lopez, Christian Alonso Becerra-Rivas, Estefany Arias-Quiroz, Mario Francisco Guerrero-Pabón

“…Abstract To evaluate the neuropharmacological profile of new spiro thiazepinone and thiazolidinone compounds in CD1 mice after a computer-aided virtual screening based on a GABA-A/BZD site. …”
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Identifying and Prioritizing Suitable Financing Methods in Mosques of the Islamic Republic of Iran by Mahdi Karimi, Mohammad Hosin Gavam, Yaser Ahmadi Beni

“…In terms of revenue-generating activities, mosque income-generating activities, charitable institutions, non-governmental public organizations, military entities, and governmental aids hold the highest importance in financing mosques.…”
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Towards Personalized Radiotherapy in Pelvic Cancer: Patient-Related Risk Factors for Late Radiation Toxicity by Anna C. Nuijens, Arlene L. Oei, Nicolaas A. P. Franken, Coen R. N. Rasch, Lukas J. A. Stalpers

“…Predicting late radiation toxicity is crucial, as it aids in the initial decision-making process regarding the treatment modalities. …”
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ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment by Xiaoying Wang, Keqing Yang, Bin Yang, Rui Wang, Yongliang Zhu, Tianhui Pan

“…Additionally, we identified a small-molecule ANKRD22 upregulator that could aid in the development of novel therapeutics targeting TAM remodeling.…”
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Evolving View of Coronary Artery Calcium: A Personalized Shared Decision-Making Tool in Primary Prevention by Omar Dzaye, Cara Reiter-Brennan, Albert D. Osei, Olusola A. Orimoloye, S. M. Iftekhar Uddin, Mohammadhassan Mirbolouk, Michael J. Blaha

“…In this article, we review the recent AHA/ACC cholesterol management guideline and contextualize the transition of CAC testing to a guideline-endorsed decision aid for borderline- to intermediate-risk patients who seek more definitive risk assessment as part of a clinician-patient discussion. …”
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From the guest editors by Urszula Ledzewicz, Avner Friedman, Jacek Banasiak, Heinz Schättler, Edward M. Lungu

“…Topics addressed at the workshop includedthe spread of infectious diseases and the growing need for robust and reliablemodels in ecology, both of special importance in the host country of SouthAfrica where research naturally has been focused on fighting disease andepidemics like HIV/AIDS, malaria and others. In the US, on the other hand, astrong emphasis exists on systems biology and on its aspects related tocancer. …”
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A New Sutureless Illuminated Macular Buckle Designed for Myopic Macular Hole Retinal Detachment by Ahmed M. Bedda, Ahmed M. Abdel Hadi, Mohamed Lolah, Muhammad S. Abd Al Shafy

“…The primary outcomes measured included aided visual acuity (BCVA) and optical coherence tomography (OCT) findings. …”
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