Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb by Danielle M. Colussi, Ryan Grainger, Megan Noble, Taylor Lake, Murray Junop, Peter B. Stathopulos

“…Remarkably, the distinct Ca2+ binding site on the central α-helix of MCUb-NTD was also identified in a functional sector of co-evolving residues, with either direct mutation to the coordinating residues or mutation to a separate site within the sector disrupting Ca2+ binding in silico and in vitro as well as enhancing mitochondrial Ca2+ uptake in cellulo. …”
Get full text

Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHL... by R. David Anderson, John W. Petersen, Puja K. Mehta, Janet Wei, B. Delia Johnson, Eileen M. Handberg, Saibal Kar, Bruce Samuels, Babak Azarbal, Kamlesh Kothawade, Sheryl F. Kelsey, Barry Sharaf, Leslee J. Shaw, George Sopko, C. Noel Bairey Merz, Carl J. Pepine

“…Objective. In a separate, contemporary cohort, we sought to confirm findings of the original Women’s Ischemia Syndrome Evaluation (WISE). …”
Get full text

Deep Transfer Learning for Classification of Late Gadolinium Enhancement Cardiac MRI Images into Myocardial Infarction, Myocarditis, and Healthy Classes: Comparison with Subjective... by Amani Ben Khalifa, Manel Mili, Mezri Maatouk, Asma Ben Abdallah, Mabrouk Abdellali, Sofiene Gaied, Azza Ben Ali, Yassir Lahouel, Mohamed Hedi Bedoui, Ahmed Zrig

“…The evaluation metrics were calculated using a separate test set. To compare the VGG16 model’s performance in feature extraction, various pre-trained base models were evaluated: VGG19, DenseNet121, DenseNet201, MobileNet, InceptionV3, and InceptionResNetV2. …”
Get full text

Risk factors of 180-day rebleeding after management of blunt splenic injury without surgery and embolization: a national database study by Chung-Yen Chen, Hung-Yu Lin, Pie-Wen Hsieh, Yi-Kai Huang, Po-Chin Yu, Jian-Han Chen

“…Multivariate logistic regression was used to identify risk factors, which were validated in a separate cohort. Results Of 6,140 patients, 80 (1.302%) experienced rebleeding within 180 days. …”
Get full text

Discrimination of Radiologists' Experience Level Using Eye-Tracking Technology and Machine Learning: Case Study by Stanford Martinez, Carolina Ramirez-Tamayo, Syed Hasib Akhter Faruqui, Kal Clark, Adel Alaeddini, Nicholas Czarnek, Aarushi Aggarwal, Sahra Emamzadeh, Jeffrey R Mock, Edward J Golob

“…In addition, a repeatability experiment using a separate dataset, experimental protocol, and eye tracker was performed with 8 participants to evaluate the robustness of the proposed approach. …”
Get full text

Assessment of the validity and reliability of the nurses’ professional values scale—revised in Persian version among nursing students by Fahimeh Alsadat Hosseini, Ladan Zarshenas, Kobra Parvan, Maryam Shaygan, Banafsheh Tehranineshat, Brian Thomson

“…Additionally, convergent and divergent validity were assessed on a separate sample of 105 nursing students. The reliability of the instrument was assessed using both internal consistency measures and the test–retest method. …”
Get full text

Effect of Auditory Recognition on the Vocabulary Knowledge of Children with Functional Articulation Disorder by YAN Jiajian, WANG Chengdong, LU Jianliang, LI Yuchang, SHEN Longbin, OU Jianlin, CHEN Zhuoming

“…There was a significant positive correlation between digit memory span test and spatial memory span task test (<italic>P</italic>&lt;0.001); there was a significant positive correlation between digit memory span test and PPVT score (<italic>P</italic>&lt;0.001); there was a significant positive correlation between spatial memory span task test and PPVT score (<italic>P</italic>&lt;0.001). 2) Auditory working memory (β=0.322, <italic>P</italic>&lt;0.001) alone had a significant mediating effect on auditory recognition function and vocabulary knowledge function; visual working memory alone (β=0.389, <italic>P</italic>&lt;0.001) had a significant mediating effect on auditory recognition function and vocabulary knowledge function.ConclusionAuditory recognition can not only directly affect vocabulary knowledge, but also affect vocabulary knowledge through a separate mediation of auditory working memory and visual working memory. …”
Get full text

The application of allelopathy in integrated pest management systems to control temperate European crop pests: a systematic map by Charlotte Kiely, Nicola Randall, Magda Kaczorowska-Dolowry

“…Each unique combination of key variables (pest, plant, allelochemical, application method, intervention form) was treated as a separate datapoint or experiment. The data was then analysed and cross-tabulated to produce descriptive statistics and heatmaps. …”
Get full text

Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…Future research in this area could include incorporating longer-term outcomes as well as validating the risk models in a separate patient population.…”
Get full text

A novel way to use cross-validation to measure connectivity by machine learning allows epilepsy surgery outcome prediction by Karla Ivankovic, Alessandro Principe, Justo Montoya-Gálvez, Linus Manubens-Gil, Riccardo Zucca, Pablo Villoslada, Mara Dierssen, Rodrigo Rocamora

“…Time intervals proportional to seizure length were more informative than the almost universally used fixed intervals.This study demonstrates that connectivity can be successfully classified with a machine learning analysis and provide information for distinguishing a separate epileptogenic functional network. In summary, the connectivity change analysis could accurately identify epileptogenic networks validated by surgery outcome classification. …”
Get full text

Integrated Assessment of the Quality of Functioning of Local Electric Energy Systems by Waldemar Wójcik, Petro Lezhniuk, Cezary Kaczmarek, Viacheslav Komar, Iryna Hunko, Nataliia Sobchuk, Laura Yesmakhanova, Zhazira Shermantayeva

“…The LEES is a part of the EPS of thermal and nuclear power plants and is considered as a separate balancing group. LEESs are designed in such a way that they can operate autonomously in both normal and extreme conditions in the EPS. …”
Get full text

Morphology, phylogeography, phylogeny, and taxonomy of Cyclorhiza (Apiaceae) by Bo-Ni Song, Xueyimu Aou, Rong-Ming Tian, Jing Cai, Wei-Yan Tan, Chang-Kun Liu, Chang-Kun Liu, Xing-Jin He, Song-Dong Zhou

“…The phylogenetic results showed that Cyclorhiza species clustered into a separate clade and S. purpureovaginatum nested within Cyclorhiza. …”
Get full text

Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: an observational study by John A Schneider, Alan G Nyitray, Derek Smith, Michael W Ross, Elizabeth Y Chiao, Timothy J Ridolfi, Bridgett Brzezinski, B R Simon Rosser, Aniruddha Hazra, Jenna Nitkowski, Sandrine Sanos, Ever Mkonyi, Lucy Mgopa

“…Using baseline data from a longitudinal study, we aimed to determine factors associated with sphincter tone and the accuracy of sphincter tonality to detect persons engaging in receptive anal intercourse.Methods Clinicians in Chicago, Houston and Milwaukee, USA conducted digital anal rectal examinations (DARE) to score sphincter resting tone (RT) and squeeze tone (ST). On a separate survey, individuals reported their preferred position for anal intercourse, that is, either always/mostly insertive anal intercourse, always/mostly receptive anal intercourse or both receptive and insertive anal intercourse. …”
Get full text

Estimation of chlorophyll-a in uncrewed aircraft systems imagery using autonomous surface vessel data with machine learning algorithms and feature selection techniques by Mohammad Shakiul Islam, Padmanava Dash, Abduselam M. Nur, Hafez Ahmad, Rajendra M. Panda, Jessica S. Wolfe, Gray Turnage, Lee Hathcock, Gary D. Chesser, Jr, Robert J. Moorhead

“…Model performance was further validated using a separate dataset and assessed through metrics such as Root-Mean-Square Difference (RMSD), Mean Absolute Relative Difference (MARD), and Average Percentage Difference (APD). …”
Get full text

Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation by Tristan Whitmarsh, Wei Cope, Julia Carmona-Bozo, Roido Manavaki, Stephen-John Sammut, Ramona Woitek, Elena Provenzano, Emma L. Brown, Sarah E. Bohndiek, Ferdia A. Gallagher, Carlos Caldas, Fiona J. Gilbert, Florian Markowetz

“…We also performed a 3D histology analysis on a separate tumour sample as a proof of principle, providing a more comprehensive visualization of vasculature morphology compared to the standard 2D cross-section of a tissue sample. …”
Get full text

A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy by Young-Hee Cho, Young-Hee Cho, Chi-Ah Chun, Chi-Ah Chun, Hector Ramos, Paul Buonora, Paul Buonora, Paul Buonora, Vasanthy Narayanaswami, Vasanthy Narayanaswami, Kim-Phuong L. Vu, Kim-Phuong L. Vu

“…Applicants’ psychosocial characteristics were obtained from a separate online survey. The acceptance status of applicants was obtained from the training programs’ records.ResultsThe applicant and non-applicant groups showed similar distribution of demographic characteristics regarding URM status and gender. …”
Get full text

Use of Indocyanine Green (ICG) to Assess Myocardial Perfusion and Territorial Distribution of Vein Grafts Implanted on Coronary Arteries in an Ex-vivo Porcine Model. A Potential Ad... by Cristiano Spadaccio, Antonio Nenna, Diletta Corrado, Carter Glenn, Antonio Panza, Russell Vester, Grzegorz Laskawski, David Rose, Louis Louis

“…Sequential fluorescence was assessed in the epicardial coronary arteries, myocardium and coronary veins using an infrared-sensitive charge-coupled device (CCD) camera system. In a separate set of experiments, SVG was used for anastomosis in end-to-side fashion to a terminal obtuse marginal (OM) branch. …”
Get full text

Validation of the version 4.5 MAESTRO ozone and NO₂ measurements by P. S. Jeffery, J. R. Drummond, C. T. McElroy, K. A. Walker, J. Zou

“…The UV-channel measurements from MAESTRO are used to retrieve profiles of ozone from the short-wavelength end of the Chappuis band (UV-ozone) and <span class="inline-formula">NO₂</span>, while measurements made in the visible part of the spectrum are used to retrieve a separate ozone (Vis-ozone) product. The latest ozone and <span class="inline-formula">NO₂</span> profile products, version 4.5, have been released, and they initially cover the period from February 2004 to December 2023, although they will continue to be updated. …”
Get full text

Pairs and his role in pattem of trade in Vilnius and Kaunas province in 1861-1914 by Aelita Ambrulevičiūtė

“…Also, the expansion of the fairs network from the eighties of the 19th century noticeably decreased the trade turnovers of a separate fair and reduced the importance of fairs as a form of wholesale trade. …”
Get full text

Validity and reliability of the Manchester Oxford Foot Questionnaire (MOXFQ) in one-year postoperative ankle fracture patients—a validation study by Michael Quan Nguyen, Marjolein Memelink Iversen, Knut Harboe, Ingvild Dalen, Aksel Paulsen

“…The structural validity and internal consistency were assessed using confirmatory factor analysis. A separate test-retest study including patients at least one year since ankle surgery was used in the assessment of reliability and measurement error. …”
Get full text