The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

Get full text

Sarcopenia in Type 2 Diabetes Mellitus: A Cross-Sectional Observational Study by L. M. Pechmann, T. H. Jonasson, V. S. Canossa, H. Trierweiler, G. Kisielewicz, R. R. Petterle, C. A. Moreira, V. Z. C. Borba

Get full text

Nutritional Innovation Using Green Seaweed (Ulva sp.) and Garlic Powder Extracts for White‐Leg Shrimp (Litopenaeus vannamei) Challenged by Vibrio harveyi by Nashwa Abdel‐Razek, Riad H. Khalil, Abeer A. M. Afifi, Afrah F. Alkhuriji, Dina M. Metwally

“…Health juveniles of L. vannamei (average weight 2–3 g) were distributed in 21 fiberglass reinforced plastic (FRP) tanks (500‐L capacity) at a stocking density of 300 animals/tank to represent each treatment in triplicate. …”
Get full text

Construction and function validation of inducible immortalized gene integration vectors by YUE Wei, YANG Yue, QIAN Baohua, LI Yanxin, GU Haihui

“…[Methods] Using gene homologous recombination technology, the coding sequences (CDS) of immortalization genes-including human telomerase reverse transcriptase (hTERT), simian virus 40 large T antigen (SV40LT), acute myeloid leukemia fusion genes NUP98-KDM5A (N/K) and CBFA2T3-GLIS2 (C/G), as well as the proto-oncogene KRAS were precisely inserted into the tetracycline (Tet)-inducible eukaryotic expression lentiviral vector pLV2-TRE3GS-EGFP-MCS-3×FLAG-hPGK-Tet-On-SV40-Neo and the transposon PB-TRE3G-3×FLAG-T2A-Puro-SV40-PA. Lentiviral packaging, cell transfection, mRNA expression analysis, Western blotting for protein detection, green fluorescent protein (GFP) visualization, and cell proliferation assays were conducted to evaluate transfection efficiency and assess the regulatory effects of Tet on gene expression in 293T and MEF cells. …”
Get full text

Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress by Clécia Dias Teixeira, Priscila Oliveira Barbosa, Wanderson Geraldo Lima, Gustavo Silveira Breguez, Miliane Martins de Andrade Fagundes, Daniela Caldeira Costa, Cintia Lopes de Brito Magalhães, Joana Ferreira Amaral, Melina Oliveira de Souza

“…Hepatotoxicity was induced in the P and GP groups by a single dose of 3 g/kg paracetamol on the last day. Paracetamol effectively induced liver damage and oxidative stress in group P animals. …”
Get full text

Integrate mathematical modeling for heat dynamics in two-phase casson fluid flow through renal tubes with variable wall properties by P. Deepalakshmi, Adil Darvesh, Hakim AL Garalleh, Manuel Sánchez-Chero, G. Shankar, E.P. Siva

Get full text

Esophageal lesions at irritable bowel syndrome by M. G. Mnatsakanyan, O. V. Tashchyan, Yu. A. Morozova, A. P. Pogromov, G. M. Dyukova, D. V. Khalyapina

Get full text

Argon release, crystallization, morphological and optical changes of ion-beam sputtered Ta2O5 thin films during thermal treatments by A. Paolone, M. Bazzan, G. Favaro, F. Borondics, G. Nemeth, F. Capitani, S. Swaraj, R. Belkhou, R. Flammini, J. Teillon, C. Michel, D. Hofman, M. Granata

Get full text

Morphological characterization and yield of pepper (Piper nigrum L.) types grown in Morogoro District, Tanzania by Abdul Jafari Shango, Ramadhani Omari Majubwa, Amon Petro Maerere

“…The highest weight of 100 fresh spikes (704.3 g) and 1000 fresh berries (164.2 g) was recorded on Ismailia. …”
Get full text

Research on the mechanism of the anti-myocardial infarction effect of the Qiliqiangxin capsule on heart failure rats via nontargeted metabolomics and lipidomics by Kuangyi Liu, Yanting Xiong, Yingli Fan, Shunhui Li, Lijuan Wu, Hui Chen, Xiaomin Wang

“…The rats were then randomly divided into the SHAM group, the MI group, the QLQX group (1.3 g/kg/day), and the VAL (valsartan) group (80 mg/kg/day). …”
Get full text

Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives by Basma T. Abd-Elhalim, Ghada G. El-Bana, Ahmed F. El-Sayed, Ghada E. Abdel-Ghani

“…The results highlighted that compounds 3b, 3g, 3h, 10b, 7, and 12 displayed strong binding energies, effectively engaging with the active sites of key proteins in various fungi such as FDC1 in A. niger, uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) in A. flavus, and Adenosine 5′-phosphosulfate kinase in P. chrysogenum. …”
Get full text

Examining the association between public health unit spending and adolescent substance use by Urvi Rai, Karen A. Patte, Brendan T. Smith, Ambikaipakan Senthilselvan, Elaine Hyshka, Scott T. Leatherdale, Roman Pabayo

Get full text

The Relationship between Intramuscular Adipose Tissue, Functional Mobility, and Strength in Postmenopausal Women with and without Type 2 Diabetes by Janet M. Pritchard, Sarah Karampatos, Karen A. Beattie, Lora M. Giangregorio, George Ioannidis, Stephanie A. Atkinson, Lehana Thabane, Hertzel Gerstein, Zubin Punthakee, Jonathan D. Adachi, Alexandra Papaioannou

Get full text

Organic rare earth feed additive to enhance Penaeus monodon’s muscle quality: A comprehensive insights into texture, amino acid, and fatty acid composition by Jiaoping Yu, Wanqi Wang, Guowei Liao, Zhen Zhang, Yuanyuan Yao, Kaimin Cheng, Jun Hu, Yalin Yang, Zhigang Zhou, Lanfen Fan

“…Shrimp in each group were fed with basal diets supplemented with 0(CON), 0.1(OREFA1), 0.2(OREFA2), and 0.3 g/kg (OREFA3) of OREFA for 56d, separately. The results revealed that the OREFA2 group showed significantly higher final body weight, weight gain and specific growth rate compared to the CON group, while exhibiting a significantly lower feed conversion rate (P < 0.05). …”
Get full text

Earliness and morphotypes of common wheat cultivars of Western and Eastern Siberia by S. E. Smolenskaya, V. M. Efimov, Y. V. Kruchinina, B. F. Nemtsev, G. Y. Chepurnov, E. S. Ovchinnikova, I. A. Belan, E. V. Zuev, Chenxi Zhou, V. V. Piskarev, N. P. Goncharov

Get full text

Synthesis of Mg-, Al- and Mg/Al-date palm fronds modified biochars: characterization and investigations on phosphorus adsorption characteristics by Jellali, Salah, Hadroug, Samar, Al-Wardy, Malik, Hamdi, Helmi,  Al-Sabahi, Jamal, Bekri, Imene, Al-Raeesi, Ahmed, Hamdi, Wissem,  Jeguirim, Mejdi

“…Notably, the corresponding Mg and Al contents; BET surface area and total pore volume were evaluated to 99.6 and 136.0 mg·g–1; 180.0 m2·g–1 and 0.09 cm3·g–1, respectively. Batch P recovery assays showed that P recovery efficiency by the three studied biochars was influenced by the contact time, the initial aqueous pH, P concentration and also the presence of foreign anions, especially nitrates and chlorides. …”
Get full text

慢性乙型肝炎患者血清HBV DNA载量与肝组织病理改变的分析

“…G3~4 28例,其血清HBV DNA载量(lg copies/mL)分别为2.1 ± 1.9?4.7 ± 2.2?5.6 ± 2.3,G2?G3~4者血清HBV DNA载量较G0~1者高(P = 0.001),G2与G3~4者血清HBV DNA载量无差异(P = 0.332);肝组织纤维化程度S0~1 10例?…”
Get full text

Chiral Pesticides in Soil and Water and Exchange with the Atmosphere by Terry F. Bidleman, Andi D. Leone, Renee L. Falconer, Tom Harner, Liisa M.M. Jantunen, Karin Wiberg, Paul A. Helm, Miriam L. Diamond, Binh Loo

Get full text

Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma by A. Y. Tikunov, A. N. Shvalov, V. V. Morozov, I. V. Babkin, G. V. Seledtsova, I. O. Voloshina, I. P. Ivanova, A. V. Bardasheva, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

Get full text

Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

Get full text