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Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…These results potentially point TRPM2 channel to be involved in AD through glial cells. …”
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Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins.
Published 2025-01-01“…G-protein coupled receptors inhibit Cav2.2 N-type Ca2+ channels by a fast, voltage-dependent pathway mediated by Gαi/Gβγ and a slow, voltage-independent pathway mediated by Gαq-dependent reductions in phosphatidylinositol 4,5-bisphosphate (PIP2) or increases in arachidonic acid. …”
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Ionotropic Glutamate Receptors and Voltage-Gated Ca2+ Channels in Long-Term Potentiation of Spinal Dorsal Horn Synapses and Pain Hypersensitivity
Published 2013-01-01“…Mechanisms that underlie LTP of spinal DH neurons include changes in the numbers, activity, and properties of ionotropic glutamate receptors (AMPA and NMDA receptors) and of voltage-gated Ca2+ channels. Here, we review the roles and mechanisms of these channels in the induction and expression of spinal DH LTP, and we present this within the framework of the anatomical organization and synaptic circuitry of the spinal DH. …”
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Lack of UBE3A-Mediated Regulation of Synaptic SK2 Channels Contributes to Learning and Memory Impairment in the Female Mouse Model of Angelman Syndrome
Published 2022-01-01“…The shunting effect of SK2 channels on NMDA receptor was significantly larger in female AS mice as compared to female WT mice. …”
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Effects of Prosopis farcta Root Extract in the Vascular Reactivity of Isolated Goat Coronary Artery
Published 2019-08-01Subjects: “…Prosopis farcta, vascular reactivity, K channels, Ca 2 channels, endothelium-derived relaxing factors, endothelium derived-hyperpolarizing factor…”
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Cordycepin Decreases Compound Action Potential Conduction of Frog Sciatic Nerve In Vitro Involving Ca2+-Dependent Mechanisms
Published 2015-01-01“…However, the depressive action of cordycepin on amplitude and conductive velocity was not observed in Ca2+-free medium or in the presence of Ca2+ channel blockers (CdCl2/LaCl3). Pretreatment with L-type Ca2+ channel antagonist (nifedipine/deltiazem) also blocked cordycepin-induced responses; by contrast, T-type and P-type Ca2+ channel antagonists (Ni2+) failed to block such responses. …”
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Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells
Published 2023-12-01“…ACTH-induced Ca2+ influx and cortisol production were suppressed by a voltage-sensitive L-type Ca2+ channel blocker but not by a T-type, N-type, or P-type Ca2+ channel blocker. …”
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Synaptic transistor implementing potentiation or depression via field distribution modulation of dual dielectric layers by single-polarity pulsed voltage stimuli
Published 2025-03-01“…The device is fabricated using a standard complementary metal-oxide-semiconductor process and is composed of a TiO2 channel deposited over a dual dielectric of SiOx on Al2O3. …”
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Research on accurate ranging of UWB under indoor environments
Published 2007-01-01“…The accurate ranging ability of ultra wideband(UWB) signal under IEEE 802.15.4a indoor channel model was studied.An improved time-of-arrival(TOA) estimation algorithm which utilizes region search and threshold comparison was proposed.By statistical analysis on certain characteristics of the CM1 and CM2 channel profiles,the probability model of TOA estimation error was deduced.The thresholds of the proposed TOA estimation algorithm were then set by limiting the error probability to the lowest level.The mean absolute ranging errors under different SNR were simulated.Results show that high enough SNR should be guaranteed in order to obtain centimeter-level ranging precision under in-door environments,while extremely high SNR would not help to improve the ranging precision any more but lead to a performance floor.The results have instructional significance on designing localization algorithms and transmission power control in practical ranging.…”
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Performance of Convolution Codes Based on 60 GHz Inter-Chip Wireless Interconnection System
Published 2015-05-01“…The characteristics of CM7.2 channel and received signa1-to-noise ratio(SNR)were analyzed. …”
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Function of nodal cilia in left-right determination: Mechanical regulation in initiation of symmetry breaking
Published 2024-10-01“…This activation results in frequent calcium transients in the cilia via the Pkd2 channel, which leads to the degradation of Dand5 mRNA only at the left-side crown-cells. …”
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Single‐ended 2 ch. × 3.4 Gbit/s dual‐mode near‐ground transmitter IO driver in 45 nm CMOS process
Published 2017-03-01“…The measured eye shows 17.8% vertically and 19.5% horizontally with finite impulse response (FIR) tap control for 15.75″ FR4 channel. The proto‐type 2 channel single‐ended driver has been implemented in 45 nm CMOS process and occupies 0.022 mm2 chip area.…”
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Feshbach hypothesis of high-Tc superconductivity in cuprates
Published 2025-01-01“…We perform a theoretical analysis of interactions between spin-polaron charge carriers in doped Mott insulators, modeled by a near-resonant two-channel scattering problem, and report evidence for Feshbach-type interactions in the $${d}_{{x}^{2}-{y}^{2}}$$ d x 2 − y 2 channel, consistent with the established phenomenology of cuprates. …”
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Phylogenetic and structural analysis of annexins in pea (<i>Pisum sativum</i> L.) and their role in legume-rhizobial symbiosis development
Published 2021-09-01“…Quantitative RT-PCR analysis showed that PsAnn4 was upregulated at the early stages of symbiosis development, starting from 1–3 days after inoculation to up to 5 days after inoculation, while experiments with the Ca2+ channel blocker LaCl3 revealed its negative influence on this expression. …”
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A Novel Rat Infant Model of Medial Temporal Lobe Epilepsy Reveals New Insight into the Molecular Biology and Epileptogenesis in the Developing Brain
Published 2024-01-01“…Several candidates, such as the low-voltage-activated Ca2+ channel Cav3.2 and the auxiliary subunits β1 and β2, which were previously reported to be upregulated in the hippocampus of the adult pilocarpine mTLE model, were found to be downregulated (together with Cav2.1, Cav2.3, M1, and M3) in the hippocampus and cortex of our InfRPil-mTLE model. …”
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Suppression of Aldosterone Synthesis and Secretion by Channel Antagonists
Published 2012-01-01“…Recently, several groups have reported that some dihydropyridine Ca2+ channel blockers (CCBs) have inhibitory actions on aldosterone production in in vitro and in the clinical setting. …”
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Development of an ISOBUS-compliant communication node for multiple machine vision systems on wide boom sprayers for nozzle control in spot application schemes
Published 2025-03-01“…The MVN consists of an electronic control unit (ECU) built around a single-board computer, equipped with a 2-channel CAN hat and an Ethernet router. The ECU utilizes AgIsoStack++ library to maintain ISOBUS compliance, enabling data exchange between the MVN and other electronic components on the sprayer. …”
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LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model
Published 2019-01-01“…Western blot analyses showed significant downregulation of NaV1.5, ERG, KCNE1, and KCNE2 channel proteins in the HF vehicle group compared with the sham group. …”
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