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Exploring Magnetic Fields in Molecular Clouds through Denoising Diffusion Probabilistic Models
Published 2025-01-01“…We trained three versions of the DDPM model: the 1-channel DDPM (using only column density), the 2-channel DDPM (incorporating both column density and polarization angles), and the 3-channel DDPM (which combines column density, polarization angles, and LOS nonthermal velocity dispersion). …”
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22
Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
Published 2025-01-01“…Analyzing prior KCNQ2 channel cryoelectron microscopy models revealed G256 as a node of an arch-shaped non-covalent bond network linking S5, the pore turret, and the ion path. …”
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23
Vasorelaxant effects and its mechanisms of the rhizome of Acorus gramineus on isolated rat thoracic aorta
Published 2025-02-01“…Since vasodilatory mechanisms associated with VSMC are predominantly influenced by K+ and Ca2+ channels, we explored various channels, including calcium-activated K+, voltage-dependent (delayed rectifier) K+, ATP-sensitive K+, inwardly rectifying K+, receptor-operated Ca2+ (ROCC), and voltage-dependent Ca2+ channels (VDCC). …”
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24
Suppressing Jahn-Teller distortion of MnO2 via B-Ni dual single-atoms integration for methane catalytic combustion
Published 2025-01-01“…This paper describes the integration of B-Ni dual single-atoms within MnO2 channels to serve as an electronic reservoir to direct the electron transfer route during methane catalytic combustion. …”
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25
Alteration of Sarcoplasmic Reticulum Ca2+ Release in Skeletal Muscle from Calpain 3-Deficient Mice
Published 2009-01-01“…Inhibition of L-type Ca2+ channels (LCC) suppressed the caffeine-induced [Ca2+]i responses in −/− myotubes. …”
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26
Effects of the dynamics of noise-induced calcium signals in a biophysical model of the astrocytic process
Published 2025-01-01“…The model describes the process of generation of spontaneous Ca2+ signals induced by the stochastic activation of voltage-dependent Ca2+ channels on the plasma membrane of the astrocyte. …”
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27
Endothelial calcium firing mediates the extravasation of metastatic tumor cells
Published 2025-02-01“…Lastly, we identified P2X4, TRP, and Piezo1 mechano-gated Ca2+ channels as key mediators of the process. These results further highlight the central role of endothelial remodeling during the extravasation of TCs and open avenues for successful therapeutic targeting.…”
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28
Climate change and the single cell
Published 2024-12-01“…This cycle involves Ca2+ channels, auxin efflux “PIN” proteins, and an auxin-activated proton pump that dissociates AGP-Ca2+ on demand. …”
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29
Inhibitory Effect of Cinobufagin on L-Type Ca2+ Currents, Contractility, and Ca2+ Homeostasis of Isolated Adult Rat Ventricular Myocytes
Published 2014-01-01“…CBG inhibited L-type Ca2+ channels, and reduced [Ca2+]i and contractility in adult rat ventricular myocytes. …”
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30
Cybersquatting Actions on Domain Name Trademark Rights as the Internet Web
Published 2024-12-01“…The parties can resolve it through 2 channels, namely through litigation and also through non-litigation. …”
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31
The Plasma Membrane Ca2+-ATPase2 (PMCA2) Is Involved in the Regulation of Purkinje Cell Dendritic Growth in Cerebellar Organotypic Slice Cultures
Published 2013-01-01“…This effect is mediated by calcium influx through P/Q-type and T-type Ca2+ channels. We have now studied the role of the plasma membrane Ca2+-ATPase2 (PMCA2), a major calcium extrusion pump, for Purkinje cell dendritic development. …”
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32
Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone
Published 2012-01-01“…In a broad pharmacological survey, the relevance of different Ca2+-related mechanisms on methadone-induced DCD was investigated including extracellular calcium, L-type Ca2+ channels, μ-opioid receptor, mitochondrial inner membrane potential, mitochondrial ATP synthesis, mitochondrial Ca2+/2Na+-exchanger, reactive oxygen species, and mitochondrial permeability transition. …”
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33
反义ClC-3寡核苷酸对thapsigargin触发 的Ca2+ 运动的影响
Published 2008-01-01“…Ca2+ 池操纵性Ca2+ 通道(store-operated Ca2+ channels, SOCC)阻断剂SK&F96365可以浓度依赖的抑制TG触发的PC12细胞Ca2+ 内流,但与随义?…”
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34
Non-apical plateau potentials and persistent firing induced by metabotropic cholinergic modulation in layer 2/3 pyramidal cells in the rat prefrontal cortex.
Published 2024-01-01“…Pharmacological tests indicated that the non-apical L2/3 PPs depend on transient receptor potential (TRP) cation channels, both TRPC4 and TRPC5, and require external calcium (Ca2+) and internal Ca2+ stores, but not voltage-gated Ca2+ channels, unlike Ca2+-dependent PPs in other cortical pyramidal neurons. …”
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