Real-Life Effectiveness and Safety of Selective Laser Trabeculoplasty as Primary, Adjunctive, and Substitutive Therapy by David Oliver-Gutierrez, Osvaldo Guevara-Chavarría, Shirin Djavanmardi, Gloria Segura-Duch, Marta Castany, Stefania Piludu, Carlos A. Arciniegas-Perasso, Elena Ávila, Elena Milla, Susana Duch

“…Survival in the PT and AT groups was defined as ≥20% IOP reduction from baseline and IOP ≤21 on two consecutive visits with the same or fewer medications and no additional glaucoma procedure, including repeat SLT. Survival in the ST group was defined as decreasing topical medication while maintaining or reducing IOP. …”
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Privacy-preserving record linkage by a federated trusted third party (fTTP) – unlocking medical research potential in Germany by Hampf, Christopher, Bialke, Martin, Hund, Hauke, Fegeler, Christian, Lang, Stefan, Penndorf, Peter, Wöller, Nico, Moser, Frank-Michael, Blumentritt, Arne, Schuldt, Ronny, Seidel, Florian, Brunecker, Peter, Wettstein, Reto, Arnecke, Lukas, Hoffmann, Wolfgang

“…., in cases in which incidental findings require contacting a participant in research projects. A clearing procedure is set up to manage potential matches in order to minimize homonym and synonym errors. …”
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Demographics and outcomes of acute type A aortic dissection in young adults in southeastern China: impact of syndromic heritable thoracic aortic disease by Xin-fan Lin, Hang-qi Gao, Qing-song Wu, Yu-ling Xie, Liang-wan Chen, Lin-feng Xie

“…Most patients underwent extensive arch procedures and in-hospital mortality rate of patients was 14.2%, which was higher in the HTAD group than in the non-HTAD group (20.0% vs. 11.0%, p = .142). …”
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The role of intraoperative monitoring in target selection in deep brain stimulation: A single centre study by Sandro Ibrulj, Dejan Georgiev, Žiga Samsa, Polona Mušič, Mitja Benedičič, Maja Trošt

“…Conclusion: This retrospective analysis confirms the benefit of MER and intraoperative test stimulation during DBS surgery in determining the final electrode position during the early / initial period of implementing the procedure. Our findings show a learning curve in successful preoperative planning in our centre achieved through experience.…”
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Comparison of effect of remimazolam and propofol on respiration of patients under deep sedation for colonoscopy: a prospective multicenter randomized controlled trial by Zhengjia Wang, Renshu Zhan, Liqun Mo, Jin Zhang, Jie Hu, Shoupeng Tan, Qiongzhen He, Ping Li, Wekong Sun, Xiaobin Wang, Jun Jiang, Li Liu, Yingying Zhang, Yiping Bai

“…MV at 1 min, 2 min, 4 min post-induction, and at the end of the procedure were higher in Group Rem than those in Group Pro (P < 0.001). …”
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Bioactivity of endodontic biomaterials on dental pulp stem cells through dentin by Bahar Javid, Narges Panahandeh, Hassan Torabzadeh, Hamid Nazarian, Ardavan Parhizkar, Saeed Asgary

“…Human molars were sectioned to obtain 0.1-, 0.3-, and 0.5-mm-thick dentin discs, which were placed between the 2 chambers to simulate an IPC procedure. Then, MTA and CEM were applied on one side of the discs, while hDPSCs were cultured on the other side. …”
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WHO program «MONICA-psychosocial»: insomnia and biological markers in the male population aged 25-64 years by V. . Gafarov, M. . Voevoda, E. . Gromova, V. . Maximov, A. . Gafarova, I. . Gagulin, N. . Yudin, T. . Mishakova, D. . Panov

“…For assessment of sleep levels scale Jenkins was used. Procedures have been standardized and strictly comply with the requirements of the protocol of the «MONICA». …”
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Cattle rumen inoculated Gliricidia sepium with poultry manure: Pretreatment, biogas production, and optimization by O.S. Oladejo, S.O. Dahunsi, E.L. Odekanle, O.A. Odeleye, O.S. Aroyewon, A.O. Oladele, G.S. Fala, A.A. Olanipekun, A.O. Abiola, J.O. Ojediran, O.E. Ajayi, O.A. Olawuni

“…The physicochemical properties of the substrates were determined using standard procedures while the Central Composite Design (CCD) of response surface methodology (RSM) was employed for experimental design and optimization of the process parameters. …”
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Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling by Nikole J. Byrne, Christoph Koentges, Elisabeth Khan, Katharina Pfeil, Robert Sandulescu, Sayan Bakshi, Carolin Költgen, Ivan Vosko, Johannes Gollmer, Thomas Rathner, Günter Roth, Michael M. Hoffmann, Katja E. Odening, Hauke Horstmann, Luke A. Potter, Christoph Bode, Dennis Wolf, Harald Sourij, Senka Ljubojevic-Holzer, Markus Wallner, Peter P. Rainer, Simon Sedej, Daniel Scherr, Dirk von Lewinski, Adam R. Wende, Andreas Zirlik, Heiko Bugger

“…Methods and results: Mice with cardiomyocyte-specific overexpression of Sirt4 (cSirt4-Tg) or non-transgenic controls underwent transverse aortic constriction (TAC) or sham procedure. Cardiac structure, function and energy metabolism were assessed by echocardiography and working heart perfusions. …”
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Efficacy and safety of trabeculectomy versus peripheral iridectomy plus goniotomy in advanced primary angle-closure glaucoma: study protocol for a multicentre, non-inferiority, ran... by Keith Barton, Tin Aung, Ling Jin, Ping Lu, Xiulan Zhang, Robert N Weinreb, Yi Zhang, Li Tang, Guangxian Tang, Hengli Zhang, Aiguo Lv, Huiping Yuan, Yunhe Song, Fengbin Lin, DENNIS S C LAM, Lin Xie, Kun Hu, Xiaohong Liang, Yingzhe Zhang, Wulian Song, Xiaomin Zhu, Xinbo Gao, Sujie Fan, Yuying Peng, Mengfei Liao, Xin Nie, Ki-Ho Park

“…Minimally invasive glaucoma surgery (MIGS) plays an increasing role in the management of glaucoma due to its safer and faster recovery profile; cataract surgery-based MIGS is the most commonly performed such procedure in PACG. However, for patients with a transparent lens or no indications for cataract extraction, incorporation of MIGS into PACG treatment has not yet been reported. …”
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A standards-based application for improving platelet transfusion workflow by William Gordon, Maria Aguad, Layne Ainsworth, Samuel Aronson, Jane Baronas, Edward Comeau, Rory De La Paz, Justin B.L. Halls, Vincent T. Ho, Michael Oates, Adam Landman, Wen Lu, Shawn N. Murphy, Fei Wang, Indira Guleria, Sean R. Stowell, Melissa Y. Yeung, Edgar L. Milford, Richard M. Kaufman, William J. Lane

“…Conclusion: A web-based, EHR-integrated application was built and integrated into our EHR system and is now part of the standard operating procedures of our blood bank.…”
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Muscle-sparing aortic coarctation repairCentral MessagePerspective by Stephanie G. Berset, MD, Hitendu Dave, MD, Christian Balmer, MD, Anna Nowacka, Raymond Pfister, MD, Patrick O. Myers, MD, René Prêtre, MD

“…Five patients had an additional enlargement procedure on the aortic arch. 27 patients had no residual or recurrent gradient. …”
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Visual hallucinations in neurosurgery: A systematic review and two case insights into Charles Bonnet Syndrome by Erica Grasso, Giulio Bonomo, Francesco Certo, Giacomo Cammarata, Giuseppe M.V. Barbagallo

“…We present two cases of CBS following neurosurgical procedures, recruited from our department. Materials and methods: Detailed patient histories, neurological and ophthalmologic evaluations, magnetic resonance imaging (MRI), computerized perimetry, electroencephalogram (EEG), and psychiatric assessments were conducted. …”
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EDTA enhances cementum-like tissue formation, TGF-β1 & VEGF in rat molars during regenerative endodontics by Alexandre Henrique dos REIS-PRADO, Isabela Joane Prado SILVA, Juliana GOTO, Nathália Evelyn da Silva MACHADO, Gleide Fernandes de AVELAR, Juliano Douglas Silva ALBERGARIA, Raphael Escorsim SZAWKA, Marco Cícero BOTTINO, Luciano Tavares Angelo CINTRA, Edilson ERVOLINO, Antônio Paulino RIBEIRO-SOBRINHO, Francine BENETTI

“…Abstract This study investigated the influence of ethylenediaminetetraacetic acid (EDTA) irrigation on cementum-like tissue formation and TGF-β1, FGF-2, and VEGF immunolabeling during regenerative endodontic procedures (REPs) in immature rat molars. The lower first molars of 12 four-week-old male rats (80 g) underwent pulpectomy in the mesial canal and were randomly categorized into two experimental groups (n = 6): sodium hypochlorite (NaOCl) – irrigated for 5 min with 2.5% NaOCl; and NaOCl-EDTA – irrigated with 2.5% NaOCl, followed by 5 min of 17% EDTA. …”
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Cerebral morphometric alterations predict the outcome of migraine diagnosis and subtyping: a radiomics analysis by Tong-Xing Wang, Xiao-Bin Huang, Tong Fu, Yu-Jia Gao, Di Zhang, Lin-Dong Liu, Ya-Mei Zhang, Hai Lin, Jian-Min Yuan, Cun-Nan Mao, Xin-Ying Wu

“…These features were put through an all-relevant feature selection procedure within cross-validation loops to identify features with significant discriminative power for migraine diagnosis and subtyping. …”
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Truth or Myth: Is Breast Implant Illness Really an Illness? by Rami Hanna, MD, Udi Maor, MD, Meir Retchkiman, MD, Basel Abu-Ganem, MD, Julie Vaynshtein, MD, Eldad Silberstein, MD

“…The study included women with breast implants (implanted group) and those without implants or any other breast procedures (naive group). The questionnaire collected social, medical, and symptom data, stratified using the Index of Symptoms’ Severity (ISS) scale. …”
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Safety and Tolerability of Sodium Thiosulfate in Patients with an Acute Coronary Syndrome Undergoing Coronary Angiography: A Dose-Escalation Safety Pilot Study (SAFE-ACS) by Marie-Sophie L. Y. de Koning, Solmaz Assa, Carlijn G. Maagdenberg, Dirk J. van Veldhuisen, Andreas Pasch, Harry van Goor, Erik Lipsic, Pim van der Harst

“…This first dose STS was combined with verapamil and nitroglycerin required for transradial procedures. A second dose STS was administered 6 hours later. …”
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Rationale and design for the thoracic Paravertebral Adjunctive Dexamethasone Palmitate Reducing chronic pain After cardiac surgery (PANDORA) trial: a parallel-group, double-blinded... by Jing Zhao, Hui Zhang, Ziyu Zheng, Baobao Gao, Lini Wang, Chong Lei, Hailong Dong, Taoyuan Zhang, Jiao Gao, Lihong Hou

“…CPSP is defined as a new development of pain or increase in the intensity of pain at the surgical area or projected onto the innervation area of a nerve in this area after a surgical procedure that persists for at least 3 months. The nature and intensity of pain will be evaluated with a Brief Pain Inventory Short Form (BPI-SF) questionnaire.Ethics and dissemination The trial was approved by the Ethics Committee of Xijing Hospital, the First Affiliated Hospital of Air Force Military Medical University (KY20232194-C-1). …”
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A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes by Shichao Han, Shichao Han, Xinyou Wang, Xinyou Wang, Jinming Zhu, Ya Li, Ya Li, Jing Na, Jing Na, Jun Wang, Jun Wang

“…In clinical practice, utilizing the three-plane structure of the paracolpium and medially lifting the vascular plane facilitated safe, reliable dissection, exposure, and preservation of pelvic autonomic nerve function.Through clinical practice, follow-up, and analysis of 55 cases, it was observed that combining the concept of membrane anatomy with the three-plane anatomical structure of the paracolpium not only enables nerve-sparing radical hysterectomy as a bloodless surgical procedure but also ensures optimal nerve preservation, favorable oncological outcomes, and a significant reduction in perioperative complications.ConclusionGuided by the principles of membrane anatomy and the three-plane theory of the paracolpium, nerve-sparing radical hysterectomy facilitates precise preservation of pelvic autonomic nerve function in a bloodless manner, while achieving favorable oncological outcomes.…”
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Patterns of Circulating piRNAs in the Context of a Single Bout of Exercise: Potential Biomarkers of Exercise-Induced Adaptation? by Caroline Eva Riedel, Javier Ibáñez, Annunziata Fragasso, Angelika Schmitt, Manuel Widmann, Felipe Mattioni Maturana, Andreas M. Niess, Barbara Munz

“…Finally, to identify piRNAs potentially of interest in the context of exercise, different screening procedures were applied. Results: There were unique and specific changes in individual piRNA expression levels in response to exercise. …”
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