Expert Recommendations on Antithrombotic Management of Peripheral Artery Disease: Perspectives from Indian Interventional Radiologists by Balaji Patel Kola, Ajit K. Yadav, Shyamkumar N. Keshava, Rochan Pant, Ujjwal Gorsi, Gireesh Mukund Warawdekar, Virender Singh Kapoorsingh Sheorain, Nikhil Bansal, Shuvro Roy Choudhury, Swatee Halbe, Vivek Kisan Ukirde, Arun Gupta, Lijesh Kumar, Rohith Puthan Veettil, Suyash Kulkarni

“…Antithrombotic therapy for PAD is underutilized in India. Revascularization procedures are done in acute or advanced stages. While such invasive strategies are effective in some patients with PAD, these strategies are costly and carry risks, and many patients are not amenable to invasive therapy, especially in low-resource settings like in India. …”
Get full text

The dynamics of lowland river sections of Danube and Tisza in the Carpathian basin by Imre M. Jánosi, Imre M. Jánosi, István Zsuffa, István Zsuffa, Tibor Bíró, Boglárka O. Lakatos, Boglárka O. Lakatos, András Szöllősi-Nagy, Zsolt Hetesi, Zsolt Hetesi

“…Resampled time series (1-hour frequency) were evaluated by standard Fourier and Welch procedures, revealing some secondary peaks in the spectra indicating quasi-periodic components in the signals. …”
Get full text

Case Report: Whole genome sequencing identifies a novel deep intronic COL4A5 variant of uncertain significance in X-linked Alport syndrome by Hoon Seok Kim, Hoon Seok Kim, Myungshin Kim, Myungshin Kim, Jin-Soon Suh, Yeonhee Lee

“…Early genetic diagnosis facilitated timely intervention without requiring invasive procedures, emphasizing the growing role of comprehensive genomic sequencing in uncovering elusive genetic variants in clinically suspected Alport syndrome.…”
Get full text

First‐In‐Human Application of Human Umbilical Cord‐Derived Extracellular Vesicles in Tethered Spinal Cord Release Surgery by Matthias Krause, Janina Gburek‐Augustat, Daniel Gräfe, Roman Metzger, Marco Ginzel, Christoph J. Griessenauer, Lukas Grassner, Daniel Weghuber, Johann Gradl, Daniela Auer, Tanja Schally, Stefan Rund, Carina Kals, Christina Folie, Elisabeth Bayer, Mario Gimona, Eva Rohde

“…During the surgical procedure, the tethered cord was released, dermoid and lipoma tissue were resected. …”
Get full text

Most prominent challenges in translational neuroscience and strategic solutions to bridge the gaps: Perspectives from an editorial board interrogation by Dirk M. Hermann, Marco Bacigaluppi, Claudio L. Bassetti, Gabrio Bassotti, Johannes Boltze, Andrew Chan, Turgay Dalkara, Adam Denes, Exuperio Diez-Tejedor, Richard Dodel, Thorsten R. Doeppner, Egor Dzyubenko, Ayman ElAli, Tamas Fulop, Alexander Gerhard, Bernd Giebel, Janine Gronewold, Matthias Gunzer, Thomas Heinbockel, Kaibin Huang, Marcello Iriti, Hans-Otto Karnath, Kasteleijn-Nolst Trenite, Ertugrul Kilic, Giuseppe Lanza, Arthur Liesz, Tim Ullrich Magnus, Jessica Mandrioli, Ayan Mohamud-Yusuf, Thomas Müller, Suyue Pan, Luca Peruzzotti-Jametti, Stefano Pluchino, Ryszard Pluta, Aurel Popa-Wagner, Ameneh Rezayof, Mohamed L. Seghier, Xinhua Shu, Vikram Singh, Jussi Sipilä, Mark Slevin, Yamei Tang, Georgios Tsivgoulis, Giustino Varrassi, Chen Wang, Bayram Yilmaz, Maha S. Zaki, Jinwei Zhang

“…These challenges can be addressed through more clearly defined experimental procedures that closely match clinical conditions and precision-based approaches that ensure efficient therapeutic responses. …”
Get full text

Predictors of permanent pacemaker requirement in aortic stenosis patients undergoing self-expanding valve transcatheter aortic valve replacement using the cusp overlap technique by Yung-Tsai Lee, Yung-Tsai Lee, Tien-Ping Tsao, Tien-Ping Tsao, Kuo-Chen Lee, Huan-Chiu Lin, Huan-Chiu Lin, Chun-Ting Liu, Ming-Chon Hsiung, Wei-Hsian Yin, Wei-Hsian Yin, Jeng Wei, Jeng Wei

“…This study aims to identify risk factors for conduction disturbances in such patients using a specific fluoroscopic cusp overlap (COL) technique.MethodsThis retrospective study analyzed AS patients who underwent TAVR with SEV from 2019 to 2022, excluding those needing pacemakers or valve-in-valve procedures. Patients were grouped by conventional (CON) and COL techniques, with outcomes monitored using Valve Academic Research Consortium (VARC)-2 criteria.ResultsIn this cohort study of 114 patients, 17 were excluded due to pre-existing pacemakers. …”
Get full text

Enhancing grapevine viability and pathogen control through optimised hot water treatment by Margarida Lourenço, Cláudia Sofia Batalha Neto, Justino Sobreiro, Jorge Sofia

“…Contamination of plant material before and during nursery procedures with this species represents a potential risk for future vineyards. …”
Get full text

The impact of remimazolam sedation during neuraxial anesthesia on perioperative cognitive function in elderly patients: a multicenter randomized controlled study by Dan Qiao, Jia-Min Kang, Rui Zhang, Lin-Yue Zong, Ying Xu, Wei-Wei Zhang, Qi Zhou, Yan Li, Tao Han, Yue-Ming Zhang, Li-Jun Yin, Jin Xu, Shou-Shi Wang, Yuan Yuan, Qing Li, Kai-Jun Niu, Yu-Xin Zheng, Lin-Lin Zhang, Yi-Ze Li, Yi-Ze Li, Yong-Hao Yu

“…This study aimed to investigate the appropriate sedative dosage of remimazolam and its effects on perioperative cognitive function in elderly patients undergoing non-general anesthesia surgery.MethodsThis multicenter, placebo-controlled trial enrolled 330 elderly patients undergoing non-general anesthesia procedures at eight centers in China from July 2021 to February 2022, with 238 ultimately completing the study. …”
Get full text

Dellon Decompression Using WALANT: A Safe and Effective Approach for Patients with Peripheral Artery Disease by Sofija Tusheva, Gordana Georgieva, Blagoja Srbov, Savetka Paljoskovska Jordanova, Katerina Jovanovska, Stefania Azmanova Mladenovska, Muamet Memeti, Darko Aleksovski, Biljana Mileska Krzhaloska, Sofija Pejkova

“…While extensively used in hand surgery, its application in foot and ankle procedures, particularly for high-risk patients with diabetic neuropathy and peripheral artery disease (PAD), remains underexplored. …”
Get full text

Outcomes of post-traumatic osteomyelitis in a conflict setting: a retrospective cohort study in Gaza by Rasha Aqel, Mohammed Alnajjar, Krystel Moussally, Mahmoud Mattar, Innocent Nyaruhirira, Fabiola Gordillo Gomez, Justine Michel, Patrick Herard, Rupa Kanapathipillai, Mohammad Khalife, Rami Malaeb

“…Significant risk factors of recurrence included up to 3 procedures, fibula fractures, PTO with Enterobacter cloacae or Staphylococcus aureus. …”
Get full text

Blood product administration in the prehospital setting: a multisociety consensus statement by Luca Carenzo, Etrusca Brogi, Vanessa Agostini, Stefania Armani, Roberto Balagna, Maria Grazia Bocci, Antonio Cascio, Michela Ciminello, Andrea Cortegiani, Massimiliano Di Biagio, Patrizia Di Gregorio, Andrea Fabbri, Lara Gianesello, Guglielmo Imbriaco, Cristian Lupi, Lucia Mirabella, Stefano Paglia, Andrea Paoli, Silvia Pini, Silvano Rossini, Giovanni Sbrana

“…The document addresses four critical topics: the selection of blood product derivatives for prehospital use, safety requirements for their transport, documentation and traceability standards, and procedures for the return of unused components.…”
Get full text

Benefits and challenges of asynchronous telemedicine in obtaining a second opinion: a qualitative interview study by Edmund Neugebauer, Felix Muehlensiepen, Dunja Bruch, Susann May, Nadja Könsgen, Jan-Christoph Loh, Sebastian von Peter, Johannes Maximilian Albes

“…Objectives Asynchronous telemedicine-based second opinions, using a purely document-based and written procedure, offer an opportunity to support patients in their medical decision-making, particularly those who cannot secure a timely face-to-face appointment nearby. …”
Get full text

The INfectious DIsease REgistry BIObank (INDI-REBIO): protocol for the design and implementation of a single-centre, prospective registry and biobank in a tertiary care centre in I... by Maurilio Ponzoni, Carmen García, Diana Canetti, Antonella Castagna, Marco Ripa, Paolo Scarpellini, Massimo Locatelli, Simona Bossolasco, Paola Cinque, Angelo Roberto Raccagni, Elena Bruzzesi, Nicola Gianotti, Silvia Nozza, Laura Galli, Vincenzo Spagnuolo, Camilla Muccini, Ilaria Mainardi, Massimo Cernuschi, Francesca Alberton, Benedetta Trentacapilli, Maria Francesca Lucente, Riccardo Lolatto, Martina Strano, Costanza Bertoni, Francesca Sanvito, Tommaso Clemente, Flavia Passini, Chiara Tassan Din, Monica Guffanti, Girolamo Piromalli, Silvia Carletti, Elisa Cantarelli, Cristina Tresoldi, Anna Danise, Raffaele Dell’Acqua, Giovanni Gaiera, Hamid Hasson, Emanuela Messina, Giulia Morsica, Martina Ranzenigo, Caterina Uberti-Foppa, Katia Ruggieri, Viviana Castagna, Gaetana Annicchiarico, Alessandro Baglivi, Liviana Della Torre, Sabrina Bagaglio, Elisabetta Carini, Michele Bellomo, Sara Diotallevi, Flavia Badalucco Ciotta, Chiara Ballabio, Caterina Candela, Gaia Catalano, Chiara Maci, Roberta Monardo, Nicolò Moschetta, Marcella Negri, Rebecka Papaioannu Borjesson, Giacomo Ponta, Alessia Siribelli, Golnaz Torkjazi, Annapia Di Napoli, Floriana Gona, Marco Tonelli, Annunziata Macrì, Enzo Scifo

“…To advance the understanding and treatment of these diseases, biobanks and biorepositories play a crucial role in guaranteeing sample traceability through their entire life cycle (collection, acquisition and registration, processing, storage, distribution) and future analysis of clinical and biological data.Methods and analysis The INfectious DIsease REgistry BIObank (INDI-REBIO) is an observational, prospective, monocentric, open-ended registry with ad hoc procedures and a systematic collection of uniform clinical, laboratory, imaging and therapeutic data of patients with suspected or microbiologically documented bacterial, viral, fungal and parasitic infectious diseases from the IRCCS San Raffaele Hospital (Milan, Italy). …”
Get full text

Ethograms predict visual fear conditioning status in rats by David C Williams, Amanda Chu, Nicholas T Gordon, Aleah M DuBois, Suhui Qian, Genevieve Valvo, Selena Shen, Jacob B Boyce, Anaise C Fitzpatrick, Mahsa Moaddab, Emma L Russell, Liliuokalani H Counsman, Michael A McDannald

“…The results demonstrate diverse threat behaviors – in a short and simple procedure – containing sufficient information to distinguish the visual fear conditioning status of individual rats.…”
Get full text

Five-minute test to prevent postcardiotomy reexplorationCentral MessagePerspective by Shingo Kunioka, MD, Tomonori Shirasaka, MD, PhD, Masahiko Narita, MD, Keisuke Shibagaki, MD, Yuta Kikuchi, MD, Yasuaki Saijo, MD, PhD, Hiroyuki Kamiya, MD, PhD

“…The postcardiotomy reexploration rate due to intrapericardial bleeding or cardiac tamponade within 1 week after surgery and the amount of bleeding until 2 days after surgery were compared. The FMT procedure involved counting the amount of bleeding by packing 4 to 6 surgical gauze sheets for 5 minutes. …”
Get full text

Self-injurious thoughts and behaviours as the reason for contact to Norwegian emergency primary care centres: an observational study by Anita Hunsager, Fredrik A. Walby, Vivian Midtbø, Tone Morken, Valborg Baste, Ingrid Hjulstad Johansen

“…Many of the patients are known to the service through a history of similar contacts.Implications The infrequency and severity of these encounters might necessitate training, decision support and procedures to compensate for the health care personnel’s limited exposure.…”
Get full text

Indocyanine Green Fluorescence Navigation in Pediatric Hepatobiliary Surgery: Systematic Review by Carlos Delgado-Miguel, Javier Arredondo-Montero, Julio César Moreno-Alfonso, Isabella Garavis Montagut, Marta Rodríguez, Inmaculada Ruiz Jiménez, Noela Carrera, Pablo Aguado Roncero, Ennio Fuentes, Ricardo Díez, Francisco Hernández-Oliveros

“…<b>Introduction</b>: Near-infrared fluorescence (NIRF) imaging with indocyanine green (ICG) is now widely regarded as a valuable aid in decision-making for complex hepatobiliary procedures, with increasing support from recent studies. …”
Get full text

Current trends in intraoperative neurophysiological monitoring among Asia–Pacific countries: an Asia–Pacific Spine Society survey by Hideki Shigematsu, Akimasa Yasuda, Ronald Tangente, Chris Yin Wei Chan, Ajoy Prasad Shetty, Jason Pui Yin Cheung, Yong Hai, Daisuke Sakai, Kyu-Jung Cho, Chih-Wei Chen, Gabriel Liu, I Gusti Lanang Ngurah Agung Artha Wiguna, Brian Hsu, Mun Keong Kwan

“…The questionnaire covered various aspects of IONM, including its common modality, Tc-MEP details, necessities for consistent use, and recommended modalities in major spine surgeries and representative surgical procedures. Results Responses were received from 193 of 626 spine surgeons. …”
Get full text

Validity of the Nepali Ask Suicide Screening Questions tool for medical inpatients by Daman R Poudel, Arun K Sharma, Ram H Chapagain, Manisha Chapagai, Nathan J. Lowry, Mahesh R Sigdel, Krishna P Bista, Rahul Pathak, Arun Kunwar, Janna Patterson, Terrell Carter, Lisa M. Horowitz

“…Thereafter a separate team of psychologists, blind to ASQ results, conducted a brief suicide safety assessment (BSSA) as the gold standard for suicide risk screening. Results All study procedures were completed by 309 [54.0% male, mean age = 15.79(± 4.2) years] participants and were included in analysis. …”
Get full text

The development of multidisciplinary convalescence recommendations after childbirth: a modified Delphi studyAJOG Global Reports at a Glance by Zayël Z. Frijmersum, MD, Eva Van der Meij, MD, PhD, Esther V.A. Bouwsma, MD, PhD, Corine J.M. Verhoeven, PhD, Johannes R. Anema, MD, PhD, Judith A.F. Huirne, MD, PhD, Petra C.A.M. Bakker, MD, PhD

“…Recommendations were based on a literature review and a modified Delphi procedure among 16 experts. Multidisciplinary consensus of at least 67% was achieved on convalescence recommendations for 27 relevant functional activities after childbirth. …”
Get full text