The association between lower prognostic nutritional index and higher short- & long-term mortality in older adults (≥ 70 years) undergoing coronary artery bypass grafting: a retros... by Zihua Liu, Zikun Wang, Qi Huang, Bo Hu, Mingliang Li, Yilin Pan, Yangyang Sun, Hao Cao, Kai Xu, Lei Yang, Zhi Li, Yangyang Zhang, Xin Zhao

“…It has been previously utilized in prognostic assessments for other surgical procedures and receives increasing attention in the field of cardiovascular surgery. …”
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Morrey Award 2023: radial head donor plug for capitellum osteochondral autograft transfer: a cadaveric biomechanical analysis by MAJMD Bryan G. Adams, LTMD Jeremy Tran, Steven Voinier, PhD, MAJMD Donald F. Colantonio, PhD, LTCMD Michael A. Donohue, PhD, LTCMD Kelly G. Kilcoyne, PhD, LTCDO Joseph W. Galvin, PhD

“…The average cartilage thickness of the peripheral rim of the radial head and capitellum was 2.5 mm (range 1.8-3.2, standard deviation 0.4) and 2.2 mm (range 1.8-3, standard deviation 0.3), respectively. During the procedure, 2 of 8 radial heads fractured in the 8-mm plug group. …”
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The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial by Kyla Blalock, Jacqueline Pistorello, Shireen L Rizvi, John R Seeley, Francesca Kassing, James Sinclair, Linda A Oshin, Robert J Gallop, Cassidy M Fry, Ted Snyderman, David A Jobes, Jennifer Crumlish, Hannah R Krall, Susan Stadelman, Filiz Gözenman-Sapin, Kate Davies, David Steele, David B Goldston, Scott N Compton

“…A smaller-scale feasibility study was conducted to (1) evaluate implementation of hybrid telehealth and in-person interventions and (2) fine-tune online procedures. Following the feasibility study, university students (aged 18-25 years) seeking UCC services with moderate to severe suicidal ideation will enroll in the CAMPUS Trial. …”
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Prognostic impact of type 2 diabetes mellitus and coronary microvascular dysfunction in patients undergoing rotational atherectomy during PCI by Lijun Feng, Yuxuan Zhang, Chenyun Zhang, Zining Chen, Jingnan Pan, Zhiling Gao, Delong Chen, Abuduwufuer Yidilisi, Jiacheng Fang, Yiyue Zheng, Tingting Mei, Jiantao Liu, Jianping Xiang, Jinlong Zhang, Changling Li, Jifang Cheng, Jian’an Wang, Jun jiang, Jian’an Wang

“…The primary endpoint was the occurrence of major adverse cardiac events (MACEs) at 24 months after the procedure, encompassing cardiac death, myocardial infarction, target vessel revascularization, and readmission for unstable angina. …”
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Management of non-traumatic abdominal pain in the emergency department: a multicentre, stepped-wedge, cluster-randomised trialResearch in context by Anna Slagman, Liane Schenk, Dörte Huscher, Lisa Arnold, Harald Dormann, Johannes Drepper, Larissa Eienbröker, Antje Fischer-Rosinský, Johann Frick, Lukas Helbig, Dirk Horenkamp-Sonntag, Freddy Irorutola, Tim Klinge, Thomas Reinhold, Peter Schily, Britta Stier, Katharina Verleger, Andreas Wagenknecht, Yves Noel Wu, Martin Möckel

“…Interpretation: The APU process is safe and did not increase emergency department length of treatment, while patient-reported outcomes and safety were improved accompanied by an increased use of diagnostic procedures. Funding: The study was funded by the German Innovations Funds.…”
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Multistage correction of severe kyphoscoliosis and pulmonary compromise in adults through combined halo-pelvic traction and posterior spinal techniques by Deng Zhao, Zhong Zhang, Zhengjun Hu, Rui Zhong, Dengxu Jiang, Fuyi Yin, Yuanxian Leng, Yanling Yi, Yijian Liang

“…Posterior vertebra column resection (PVCR) is an effective technique for correcting kyphoscoliosis, but it is a technically demanding procedure.…”
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HyperSHArc: Single-Isocenter Stereotactic Radiosurgery of Multiple Brain Metastases Using Proton, Helium, and Carbon Ion Arc Therapy by Lennart Volz, PhD, Peilin Liu, MSc, Thomas Tessonnier, PhD, Xiaoda Cong, MSc, Marco Durante, PhD, Andrea Mairani, PhD, Wenbo Gu, PhD, Amir Abdollahi, MD, PhD, Xuanfeng Ding, PhD, Christian Graeff, PhD, Taoran Li, PhD, Stewart Mein, PhD

“…Methods and Materials: Treatment design and optimization procedures were devised using commercial and in-house treatment planning systems. …”
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Effect of liver biopsy size on MASLD fibrosis assessment by second-harmonic generation/two-photon excitation fluorescence microscopy by Daniel T. Field, Yayun Ren, Kutbuddin Akbary, Elaine Chng, Dean Tai, Nikolai V. Naoumov, David E. Kleiner, Jonathan A. Fallowfield, Timothy J. Kendall, Arun J. Sanyal

“…The impact of biopsy size and location on the accuracy of these approaches has not been assessed in MASLD, leaving quality assurance procedures undefined. Methods: One unstained section each from 100 hepatectomy/explant MASLD cases, 20 of each pathologist-assigned Non-alcoholic Steatohepatitis Clinical Research Network (NASH-CRN) fibrosis stage (F0–F4), were used to create virtual core biopsies by cropping regions from within the whole parent section. …”
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Total arch replacement with extended branched stented anastomosis frozen elephant trunk repair for type A dissection improves operative outcomeCentral MessagePerspective by Kenichi Hashizume, MD, PhD, Tadashi Matsuoka, MD, PhD, Mitsuharu Mori, MD, PhD, Hidenobu Takaki, MD, Kiyoshi Koizumi, MD, PhD, Hiroaki Kaneyama, MD, Koji Funaishi, MD, Kento Kuroo, MD, Hideyuki Shimizu, MD, PhD

“…Methods: We compared the clinical course of patients undergoing total arch replacement using sutureless direct branch vessel stent grafting with frozen elephant trunk (extended branched stented anastomosis frozen elephant trunk repair) for acute aortic dissection type A with patients undergoing conventional total arch replacement. For the procedure, the aortic arch was transected circumferentially distal to the brachiocephalic artery origin. …”
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Salivary microbiota profile in adult and children population according to active dentin caries: a metagenomic preliminary analysis by Nuria Tamayo-Estebaranz, Nuria Tamayo-Estebaranz, Carolina Muñoz-González, Ana María Gil-Valcárcel, Ana María Gil-Valcárcel, Paula Calvo López-Dávalos, Andrea Martín-Vacas, Marta M. Paz-Cortés, Juan Manuel Aragoneses

“…Alpha diversity (Chao, Observed Features, Shannon and Simpson indices) and beta diversity (PCoA plot and PERMANOVA procedure) were analysed. In addition, Linear Discriminant Analysis Effect Size (LEfSe) was used to identify differential taxa between groups. …”
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Cervical cancer screening uptake and correlates among HIV-infected women: a cross-sectional survey in Côte d’Ivoire, West Africa by Eugene Messou, Didier K Ekouevi, Boris Tchounga, Simon Pierre Boni, Jean Jacques Koffi, Apollinaire G Horo, Aristophane Tanon, Serge-Olivier Koulé, Innocent Adoubi, Antoine Jaquet

“…The aim of this study was to estimate the coverage of cervical cancer screening and associated factors among WLHIV in Abidjan, Côte d’Ivoire.Design Cross-sectional survey conducted from May to August 2017.Settings Outpatient setting in the four highest volume urban HIV clinics of government’s or non-governmental organisation’s sector in Côte d’Ivoire.Participants All WLHIV, aged 25–55 years, followed since at least 1 year, selected through a systematic sampling procedure.Intervention A standardised questionnaire administered to each participant by trained healthcare workers.Outcome Cervical cancer screening uptake.Results A total of 1991 WLHIV were included in the study, aged in median 42 years (IQR 37–47), and a median CD4 count (last known) of 563 (378-773) cells/mm3. …”
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RO5126766 attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through mediating the ERK pathway by Han Wang, Xiwen Yuan, Jie Han, Zuoxing Wu, Zheru Ma, Fan Shi, Zhengqiong Luo, Zihan Chen, Chenyang Guo, Guixin Yuan, Xuemei He, Zemin Ling, Lin Meng, Rong Shen, Jianming Huang, Ren Xu

“…Methods: This study employed the anterior cruciate ligament transection (ACLT) procedure to create an OA model in mice. The effects of RO on pathological changes in articular cartilage and subchondral bone were assessed using micro-CT and histological staining. …”
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Myocardial oxygen handling and metabolic function of ex-situ perfused human hearts from circulatory death donors by Jorik H. Amesz, MSc, Sanne J.J. Langmuur, BSc, Mark F.A. Bierhuizen, MD, LLM, Dwight Dumay, BSc, Pieter C. van de Woestijne, MD, Jelena Sjatskig, MD, Lisa E. Sluijter, MSc, Dirk J. Duncker, MD, PhD, Olivier C. Manintveld, MD, PhD, Yannick J.H.J. Taverne, MD, PhD, MSc

“…Methods: This single-center retrospective study included human DCD heart transplantation procedures using ESHP. Lactate concentrations, blood gas, myocardial oxygen consumption (MVO2), delivery (MDO2), and extraction (MEO2), coronary blood flow (CBF), coronary vascular resistance (CVR), and adenosine infusion were reported over time. …”
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Molecular testing for cytologically suspicious and malignant (Bethesda V and VI) thyroid nodules to optimize the extent of surgical intervention: a retrospective chart review by Jessica Hier, Galit Avior, Marc Pusztaszeri, Joshua R. Krasner, Noura Alyouha, Veronique-Isabelle Forest, Michael P. Hier, Alex Mlynarek, Keith Richardson, Nader Sadeghi, Michael Tamilia, Richard J. Payne

“…Therefore, molecular testing may have an important role in optimizing surgical procedures performed in the setting of Bethesda V and VI thyroid nodules. …”
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Mindful eating is associated with a healthier plant-based diet in the NutriNet-Santé study by Pauline Paolassini-Guesnier, Marion Van Beekum, Emmanuelle Kesse-Guyot, Julia Baudry, Rebecca Shankland, Angélique Rodhain, Alice Bellicha, Christophe Leys, Serge Hercberg, Mathilde Touvier, Benjamin Allès, Sandrine Péneau

“…Clinical Trial Registry: The NutriNet-Santé study was conducted in accordance with the Declaration of Helsinki, and all procedures were approved by the Institutional Review Board of the French Institute for Health and Medical Research (IRB Inserm n◦ 0000388FWA00005831) and the Commission Nationale de l’Informatique et des Libertés (CNIL n◦ 908450 and n◦ 909216). …”
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Evaluation of the efficacy of electroacupuncture on pain and tolerance for unsedated colonoscopy: A study protocol for a prospective, randomized, sham-controlled trial by Yang ZHANG, Zhi-dan WANG, Jie ZHANG, Shuang REN, Yue LIU, Yun-xi LI, Xiao-yu MA, Xu WANG, Hao SUN, Ruo-shi LIU

“…Electroacupuncture (EA) can simplify the procedure of anesthesia and analgesia, while the efficacy of EA on unsedated colonoscopy remains unclear. …”
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Effect of integrating paediatric tuberculosis services into child healthcare services on case detection in Africa: the INPUT stepped-wedge cluster-randomised trial by Lise Denoeud-Ndam, Rhoderick Machekano, Anne Cecile Bissek, Rose Masaba, Millicent Ouma, Saint Just Petnga, Martina Casenghi, Appolinaire Tiam, Stephen Siamba, Nicole Herrera, Patrice Tchendjou, Leonie Simo, Boris Kevin Tchounga, Gordon Odhiambo Okomo

“…Children with presumptive TB were enrolled after obtaining their parents’ consent and were followed throughout TB diagnostic procedures and treatment. Study outcomes included the rate of children with presumptive TB receiving TB investigations and that of children diagnosed with TB (the primary outcome was case detection), per thousand children under 5 years attending facilities. …”
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Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol by Christine Mouton, Nicolas Nesseler, Antoine Bénard, Mathieu Pernot, Alexandre Ouattara, Antoine Beurton, Alexandre Mansour, Victor-emmanuel Brett, Corinne Batsale, Anais Aitgougam, Anais Cordon, Aurelie Fresselinat, Geraldine Robert, Julien Imbault

“…Introduction Cardiac surgery remains a high-risk procedure for bleeding despite advances in patient blood management. …”
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Development and validation of a novel scoring model for predicting underlying intracranial atherosclerosis prior to endovascular treatment in acute posterior circulation large-vess... by Guoyi Peng, Guoyi Peng, Guoyi Peng, Chuming Huang, Jiaqi Huang, Qiuhui Shi, Wei Xu, Shiwei Luo, Jiong Yang, Shouxing Wang, Qiao Wu, Chuwei Cai, Hao Long, Hao Long

“…Background and objectiveDetermining the cause of occlusion prior to endovascular treatment (EVT) for acute ischemic stroke caused by large-vessel occlusion (LVO) is helpful for developing a procedure strategy. The aim of this study was to develop and validate a novel scoring model to predict intracranial atherosclerosis-related large-vessel occlusion (ICAS-LVO) in patients with acute vertebrobasilar artery occlusion.MethodsThe derivation cohort comprised 170 patients who received EVT between January 2018 and June 2024 at multiple centers. …”
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Cyanoacrylate glue in breast surgery: the GLUBREAST Trial by Emanuela Esposito, Claudio Siani, Ivana Donzelli, Anna Crispo, Sergio Coluccia, Piergiacomo Di Gennaro, Assunta Luongo, Franca Avino, Alfredo Fucito, Ugo Marone, Maria Teresa Melucci, Ruggero Saponara, Raimondo di Giacomo

“…The glue is a synthetic sealant (N-Butyl-2-CyanoAcrylate+Metacryloxisulfolane) biocompatible, CE approved for internal human uses and surgical procedures. The assumed mechanism of action in breast surgery is that the glue would create a seal coating in the operative field to occlude lymphatic leaks and limit seroma formation.Materials and methodsThe trial included 180 patients scheduled for breast-conserving surgery or for radical modified mastectomy without reconstruction. …”
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