A novel corneal indentation device for comparison of corneal tangent modulus before and after FS-LASIK in vivo by Yan Zhang, Junyu Lin, Shu-Hao Lu, Jones Iok-Tong Chong, Cheng Yang, Jianqing Lan, Wenjuan Xie, Juan Li, David Chuen-Chun Lam, Dan Cao, Jin Zeng

“…The study sought to explore changes in corneal tangent modulus after FS-LASIK, taking into account central corneal thickness (CCT) and corneal radius, to enhance our understanding of the biomechanical changes induced by this surgical procedure. Results Sixty-six patients (66 eyes) underwent FS-LASIK, resulting in significant changes in CCT, corneal radius, and Goldmann intraocular pressure (GAT IOP) 6 months post-surgery (△CCT = − 88 ± 31 µm, △corneal radius = 0.81 ± 0.30 mm, △GAT IOP = − 3.2 ± 2.4 mmHg, p < 0.001) 6 months after surgery. …”
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Beam Data Validation during Transition from Flattened to Unflattened Beams in IMRT and VMAT Delivery: An Experimental Study by Pradeep Goswami, Punam Kumari, Brijesh Goswami, Rakesh Kumar Jain, Suresh Yadav, S Choudhary, Asiya Hilal, Kishore Singh

“…Conclusion: Accurate delivery of RapidArc and IMRT plans for different beam modalities (6X and 6X_FFF), accepted CL values can be utilised as a baseline to evaluate the quality of QA procedure, accuracy and wholeness of Treatment Planning System (TPS).…”
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HOTSED: A new integrated model for assessing potential hotspots of sediment sources and related sediment dynamics at watershed scale by Manuel La Licata, Alberto Bosino, Seyed Hamidreza Sadeghi, Mattia De Amicis, Andrea Mandarino, Andrea Terret, Michael Maerker

“…We tested the HOTSED procedure in the upper Val d’Arda-Mignano watershed, which is a representative geomorphologically highly active Mediterranean area of the Northern Apennines (Italy). …”
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Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of a... by Jia-Xin Li, Jia-Xin Li, Shi-Yu Tan, Li-Qi Li, Yu-Hong Zheng, Lin Zhao, Hui-Rong Zhu, Hai-Lang He, Yan-Yu Zhang, Run-Ze Li, Tian-Yu Bao, Yi-Zhong Zhang, Xiao-Man Yang, Hao Zhang, Hui-Hui Chen, Bo-Wen Wu, Xin Lin, Xiao-Sheng Lin, Xiao-Sheng Lin, Yin Cheng Lin, Xin-Bing Sui, Ying Xie, Xian-Mei Zhou, Pei-Yu Yan

“…Thus, our aim in this project was to explore the mechanism by which tricin inhibited the progression of KRAS-mutant NSCLC much more deeply.MethodsFirst of all, we detected the acute toxicity of an intraperitoneal injection of tricin in mice according to the improved up-and-down procedure. Next, we integrated network pharmacology, molecular docking with transcriptomics analysis and biological methods to probe the underlying mechanisms of tricin in the treatment of patients with KRAS-mutant NSCLC. …”
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Persistent Low Anti-HIV Neutralizing Antibody Titers in HIV/HCV Coinfection Despite HCV Cure: A 5-Year Longitudinal Analysis by Daniel Sepúlveda-Crespo, Víctor Sánchez-Merino, Rafael Amigot-Sánchez, Almudena Rubio-Pérez, Cristina Díez, Víctor Hontañón, Juan Berenguer, Juan González-García, Felipe García, Isidoro Martínez, Eloísa Yuste, Salvador Resino

“…<i>p</i>-values were adjusted using the Benjamini–Hochberg procedure (<i>q</i>-value). <b>Results</b>: HIV-neutralizing antibody responses in HIV/HCV-coinfected individuals remained stable over five years following HCV therapy without significant changes (<i>q</i>-value > 0.05). …”
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Relationship between experiencing a challenge or delay accessing contraception and contraceptive self-efficacy: Data from a 2022 nationally representative online survey by Alex Schulte, Ariana H. Bennett, Jennet Arcara, Jamie Bardwell, Aisha Chaudhri, Laura Davis, Brittni Frederiksen, Elizabeth Jones, Catherine Labiran, Raegan McDonald-Mosley, Whitney Rice, Tara Stein, Ena Suseth Valladares, Kari White, Cassondra Marshall, Anu Manchikanti Gomez

“…Results Among the analytic sample of respondents who had ever used or tried to obtain a contraceptive product, device, or procedure (unweighted n = 2,771), about 14% experienced a challenge/delay obtaining desired contraception in the past year. …”
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Baska Mask versus I-gel in Spontaneously Breathing Anaesthetised Patients: A Randomised Clinical Study by Bhagyavardhan Botta, Yogarajan Ramalingam, Grishma Robba, Tanya Elizabeth, Kala Balasubramanian, Selvamani Subramanian, Senthil Kumar Vannivedu Santhnam, Kavyasri Morampudi

“…Materials and Methods: A prospective randomised single-blinded study was conducted in the Department of Anaesthesiology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India from October 2019 to October 2020 on 60 American Soceity of Anaesthesiology (ASA) physical status I and II patients, aged between 18-65 years, who were scheduled for minor surgical procedures while spontaneously breathing under general anaesthesia. …”
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Distinguishing atypical parotid carcinomas and pleomorphic adenomas based on multiphasic computed tomography radiomics nomogram: a multicenter study by Lin-Wen Huang, Jian-Chao Liang, Pei-Kun Cai, Zhi-Ping Cai, Mei-Lin Chen, Jia-Wei Pan, Yong-Feng Wen, Yun-Jun Yang, Zhen-Yu Xu, Ya-Bin Jin, Zhi-Feng Xu

“…Key discriminative features — cluster shade, run-length non-uniformity and first-order mean, extracted via wavelet or exponential filters — significantly differentiated atypical PCAs from PAs.ConclusionThe CT-based radiomics nomogram, supplemented by machine learning, effectively differentiates atypical PCAs from PAs, presenting a non-invasive diagnostic tool that could guide treatment decisions and reduce the need for invasive procedures.…”
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Fertility Counseling Pattern over Time in Young Patients with Breast Cancer: A Retrospective Analysis at a Large Comprehensive Cancer Center by Caterina Barbieri, Ottavia Amato, Anna Chiara Cattelan, Loris Marin, Alessandra Andrisani, Carlo Saccardi, Tommaso Giarratano, Giovanni Faggioni, Elisabetta Di Liso, Carlo Alberto Giorgi, Eleonora Mioranza, Cristina Falci, Grazia Maria Vernaci, Roberto Tozzi, Valentina Guarneri, Maria Vittoria Dieci

“…The COVID-19 pandemic represented a potential hurdle to the integration of these procedures into clinical practice. This study aims to describe the time-related evolution in addressing oncofertility issues. …”
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Ultrasound-guided coracobrachialis plane musculocutaneous nerve block for perioperative analgesia in pediatric Gartland type III supracondylar humerus fracture: a prospective pilot... by Tianyi Gao, Zhuorun Song, Shunyi Lu, Nan Song, Wentao Yu, Huilin Yang, Jun Zou, Qian Wang, Jun Ge

“…SC-BPB: 1.00 (1.00), **p = 0.0014]. Procedure duration favored Cora-MNB [4.54 ± 1.21 (min) vs. 9.02 ± 1.94 (min), T = 14.32, 95% CI: 3.88–5.12, ***p &lt; 0.001], with higher surgical and parental satisfaction scores. …”
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Clinical outcomes of double-flap technique versus gastric tube reconstruction following laparoscopic proximal gastrectomy: a multicenter propensity score-matched cohort study by Zhu Jingtao, Chen Shaoqin, Zhang Tao, Yang Li, You Sheng, Hong Qingqi, Lin Hexin, Chen Yinan, Yu Huangdao, Chen Yifu, Yu Xuejun, You Jun

“…Abstract Background Various anti-reflux procedures are currently utilized for digestive tract reconstruction following proximal gastrectomy (PG), but the optimal reconstruction method remains debated. …”
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Establishment and optimization of a system for the detection of Candida albicans based on enzymatic recombinase amplification and CRISPR/Cas12a system by Xiaotong Zeng, Qiuyang Jiang, Fo Yang, Qianlin Wu, Tingyao lyu, Qi Zhang, Jin Wang, Feng Li, Dayong Xu

“…This one-step detection platform simplifies and expedites the procedure, achieving a sensitivity level on par with that of two-step methods. …”
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A prospective multi-site study to evaluate the performance and usability of an oral fluid-based HIV self-test in Canada by Richard A. Galli, Darshanand Maraj, Kristin McBain, Jason M. Lo Hog Tian, Abbey McFarland, Wangari Tharao, Nontobeko P. Nkala, Arlene Chan, Mark da Silva, Rejean Thomas, Anne-Fanny Vassal, Martin Lepage, Laurie Ireland, Mike Payne, Jared Starr, Chris Fraser, Marion Selfridge, Mona Loutfy, Roberta Halpenny, Nirubini Jeyarajah, Vanessa Tran, Tony Mazzulli, Sean B. Rourke

“…Descriptive statistics were used to summarize usability self-test procedure steps. Results Overall, 951 participants were recruited and consented with 911 available for all analyses. …”
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Spatially remotely sensed evapotranspiration estimates in Sahel region using an ensemble contextual model with automated heterogeneity assessment by Nesrine Farhani, Jordi Etchanchu, Gilles Boulet, Philippe Gamet, Albert Olioso, Alain Dezetter, Ansoumana Bodian, Nanée Chahinian, Kanishka Mallick, Chloé Ollivier, Olivier Roupsard, Aubin Allies, Jérôme Demarty

“…From this analysis, an automated procedure of method selection according to the heterogeneity conditions is proposed. …”
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Surgical Management of Sacral Bone Tumors: A Retrospective Analysis of Outcomes, Complications, and Survival by Chiara Cini, Emanuela Asunis, Cristiana Griffoni, Gisberto Evangelisti, Giuseppe Tedesco, Riccardo Ghermandi, Marco Girolami, Valerio Pipola, Silvia Terzi, Giovanni Barbanti Brodano, Stefano Bandiera, Stefano Boriani, Alessandro Gasbarrini

“…<b>Conclusions</b>: Sacrectomy remains a challenging procedure with substantial morbidity and variability in outcomes. …”
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COVID-19 vaccination pharmacovigilance in Khojaly district, Uzbekistan: an epidemiological evaluation by Yunis Tursinov, Yunis Tursinov, Yunis Tursinov, Roberta Horth, Roberta Horth, Roberta Horth, Botirjon Kurbonov, Alfiya Denebayeva, Alfiya Denebayeva, Shalkar Adambekov, Shalkar Adambekov, Dilyara Nabirova, Dilyara Nabirova, Dilyara Nabirova

“…Improving the AEFI registry and training providers on standard operating procedures for identifying, reporting, and investigating AEFI could improve vaccine safety surveillance.…”
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Impact of parathyroid gland classification on hypoparathyroidism following total thyroidectomy with central neck dissection for differentiated thyroid cancer by Qixuan Sheng, Wei Li, Ping Zhang, Qiang Wang, Siluo Zha, Wensheng Rao, Bin Wang, Xinyun Xu, Ming Qiu, Wei Zhang, Chengxiang Shan

“…Notably, DTC patients with more than two tightly connected PGs are at an elevated risk of developing temporary hypoparathyroidism, emphasizing the importance of meticulous parathyroid preservation during surgical procedures.…”
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The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows by Mónica Madrigal-Valverde, Marcus Vínicius Galvão Loiola, José Esler Freitas Junior, Murilo Ramos Santiago, Lara Lôbo Dantas, Artur Azevedo Menezes, Sandro Percário, Everton Luiz Pompeu Varela, Eduardo Costa, Endrigo Adonis Braga de Araujo, Rodrigo Freitas Bittencourt

“…Data were statistically analyzed using mixed-model procedures with repeated measures over time. Results: Significant interactions between treatment and time were observed for hematocrit, red blood cells, and hemoglobin (p < 0.05), indicating physiological adaptations potentially related to increased water intake. …”
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The efficacy of neuroendoscopic surgery treating patients with thalamic hemorrhage accompanied by intraventricular hematoma by Feilong Yang, Feilong Yang, Wuhuan Xu, Xielin Tang, Yan Yang, Buqian A. Ku, Yiping Zhang, Xiaoli Yang, Wei Xie, Xuhui Hui

“…Neuroendoscopic surgery is a safe and effective procedure for treating thalamic hemorrhage accompanied by intraventricular hematoma.…”
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Incidence of Gallstones in Patients with Obesity After Bariatric Surgery in Northern Saudi Arabia: A Cross-Sectional Study by Abdulrahman Omar A. Alali, Abdualaziz Fayez Alhumidi Alanazi, Mohammed Abdulaziz M. Albarghash, Rakan Nasser Abdullah Alruweli, Mohammed Bader H. Alanazi, Ibrahim Farhan B. Alanazi, Turkey Saleh H. Alrowaily, Rakan Khalid Marzouq Alanazi, Baraah AbuAlsel, Fadih Nada M. Alenezi, Rashad Qasem Ali Othman, Manal S. Fawzy

“…Conclusions: Gallstone formation after bariatric surgery in this population is influenced by female sex, rapid postoperative weight loss, and lack of prophylactic medication, while the type of surgical procedure does not significantly affect risk. Focused monitoring and preventive strategies, particularly in high-risk groups, are recommended to reduce gallstone-related complications following bariatric surgery.…”
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