REGγ regulates antiviral response by activating TBK1-IFNβ signaling through degradation of PPP2CB by Yi Li, Pei Wang, Jiamin Ma, Qing Tu, Yuan Yuan, Ying Chen, Lin Wang, Yuwei Chen, Feng Chen, Suvi Biesinger, Henry J. Li, Jinbao Li, Liangfang Yao

“…In conclusion, our work demonstrates that REGγ is a positive modulator of IFNβ signaling during antiviral response, highlighting that this procedure is regulated via REGγ degradation of PPP2CB and provides a new insight into the coordination between antiviral response and proteasome activity. …”
Get full text

Cas12a Cis-cleavage mediated lateral flow assay enables multiplex and ultra-specific nucleic acid detection by Mei Lin, Zhiqiang Qiu, Mengen Hao, Weiwei Qi, Ting Zhang, Yuting Shen, Hongrui Xiao, Chaoyue Liang, Longxu Xie, Yongzhong Jiang, Meng Cheng, Tian Tian, Xiaoming Zhou

“…Additionally, we present a portable device to automate nucleic acid amplification and strip detection procedures, showcasing the potential of cc-LFA for future applications in decentralized laboratory scenarios.…”
Get full text

Influence of Various Fruit Preservation Methods on the Phenolic Composition and Antioxidant Activity of <i>Prunus spinosa</i> L. Fruit Extract by Valentina Sallustio, Joana Marto, Lidia Maria Gonçalves, Manuela Mandrone, Ilaria Chiocchio, Michele Protti, Laura Mercolini, Barbara Luppi, Federica Bigucci, Angela Abruzzo, Teresa Cerchiara

“…In this study, blackthorns were preserved using different methods (air-drying, freezing, or freeze-drying) to determine the optimal procedure for preserving their antioxidant activity. …”
Get full text

Direct brow lifting: Specific indications for a simplified approach to eyebrow ptosis by Michele Pascali, Ilaria Bocchini, Anna Avantaggiato, Francesco Carinci, Valerio Cervelli, Fabrizio Orlandi, Davide Quarato

“…The main complication associated with this procedure was visibility of the scar in two patients. …”
Get full text

Bronchial Artery Embolization in Hemoptysis by Dea Putri Audina, Fathiyah Isbaniah, Dicky Soehardiman, Andi Darwis, Bagus Radityo Amien

“…Despite these advantages, recurrence rates range widely from 10–55%, often due to incomplete embolization, vessel recanalization, and collateral vessel development. The procedure employs embolic agents such as polyvinyl alcohol (PVA) particles, gelatin sponges, and tris-acryl gelatin microspheres, with minimal complications such as spinal cord infarction or broncho-esophageal fistulas. …”
Get full text

Complications from the formation of preventive stomas in the surgical treatment of rectal cancer by I. I. Aliev, A. A. Smirnov, R. V. Pavlov, K. N. Komyak, D. A. Ivlev, N. A. Domanskiy, G. A. Sharygin, A. I. Nazmiev

“…In compliance with the standardized surgical procedures and the protocol of perioperative management of patients, the number of severe complications is minimal. …”
Get full text

Evaluation of sonication for the detection of periprosthetic joint infection in hip revision arthroplasty: a retrospective observational single-center study of 288 episodes by Bernhardt Kickinger, Tor Monsen, Emma Karis, Micael Widerström, Petter Sundin, Kjell G Nilsson, Volker Otten, Sead Crnalic

“…The inclusion criteria were a minimum of 2 perioperative tissue cultures collected at the index procedure and sonication performed on a removed implant. …”
Get full text

Advances in Coccygectomy: A Comprehensive Review Evaluating Surgical Techniques for Coccygodynia by Barnabas Obeng-Gyasi, Ethan D. L. Brown, Anoop Sai Chinthala, Gordon Mao

“…Emerging minimally invasive procedures may further reduce complications and enhance recovery. …”
Get full text

Mental health needs in the acute and subacute phases of the 2024 Noto Peninsula earthquake: Emergency Medical Information System data analysis in Disaster Psychiatric Assistance Te... by Yasuto Kunii, Yumiko Hamaie, Mizuki Hino, Yusuke Utsumi, Yasuhisa Fukuo, Hiroaki Tomita

“…Abstract Aim As it is difficult to examine the mental health of disaster victims immediately after a disaster through the rigorous procedures required for academic papers, the overall mental state of victims immediately after a disaster is not well understood. …”
Get full text

Urolithin A supplementation to improve endothelial and cerebrovascular function in middle-aged adults with obesity: Study protocol for a double-blind placebo-controlled randomized... by Ana Clara da C. Pinaffi-Langley, Camila B. Pinto, Zsofia Szarvas, Anna Peterfi, Zalan Kaposzta, Peter Mukli, Mihaly Muranyi, Cameron D. Owens, Cheryl Adams, Ali Shahriari, Henry Kinnard, Jr., Bryan Ticer, Leah Anderson, Stefano Tarantini, Yan Daniel Zhao, Norman G. Hord, Andriy Yabluchanskiy

“…Thus, this protocol details the procedures of a study designed to investigate the effect of 4 weeks of UroA supplementation on endothelial and cerebrovascular function in middle-aged adults with obesity. …”
Get full text

Calibration of ionization chamber in megavoltage x-ray field of medical linear accelerator by Pham Hong-Lam, Hoang Thanh-Phi-Hung, Sunjun Jin, Bui Duy-Linh, Nguyen Tuan-Khai, Bui Van-Loat, Le Tuan-Anh, Nguyen Huu-Quyet, Pham Duc-Khue, Phan Viet-Cuong, Phan Tien-Dung, Pham Quang-Trung, Tran Hoai-Nam, Le Ngoc-Thiem

“…The calibration factors of IC-1, ND1,D,w, Q were deduced (for beam qualities Q of MeV X-ray fields with maximum energies of 6 MeV and 15 MeV). The identical procedure was applied to two other ionization chambers (IC-i, i=2,3) to obtain absorbed doses to water at a depth of 10 cm (referred to as Di-new10) using the new beam quality correction factor. …”
Get full text

What paediatricians need to know about modern urologic management of vesicoureteral reflux by Jeanne Goulin, Jeanne Goulin, Jeanne Goulin, Delphine Demède, Delphine Demède, Bruno Ranchin, Mélodie Mosca, Aurélie De-Mul, Valeska Bidault Jourdainne, Valeska Bidault Jourdainne, Valeska Bidault Jourdainne, Valeska Bidault Jourdainne

“…With minimally invasive surgery becoming increasingly common among pediatric urologists, treatment modalities for VUR have evolved significantly, and endoscopic, laparoscopic, and robotic-assisted procedures now play a central role in surgical management. …”
Get full text

AngioSim: A Novel Augmented-Reality Angiography Simulator for Radiation-Free Neurointerventional Training by Jan Gottfried Minkenberg, Smit Khandelwal, Ilya Digel, Martin Wiesmann, Thorsten Sichtermann

“…However, training in angiographic procedures often entails exposure to ionizing radiation, which carries inherent risks. …”
Get full text

Triple-Row Modification of Knotless Speed Bridge Technique for Rotator Cuff Repair by Roger V. Ostrander MD, Skyler T. Hoelscher MD, Eric A. Branch MD, Reece Vesperman MD, Cooper Williams, Garrett Flynn

“…Background: Rotator cuff pathology is the leading cause of shoulder-related disability, with approximately 250,000 rotator cuff procedures performed annually in the United States. …”
Get full text

Smart 3D-printed facades: a review of innovations, materials, and sustainable performance by Dan-Radu Baraboi, Luminița Maria Scutaru, George Dragomir, Alin Ionuț Brezeanu, Răzvan Calotă, Mihaela Pavel, Gabriel Năstase

“…Critical challenges persist, including concerns regarding long-term durability, cost-effectiveness, scalability for large-scale applications, and the establishment of standardized testing and certification procedures. Future research should prioritize comprehensive lifecycle assessments to quantify environmental impacts and focus on developing robust material performance models under diverse climatic conditions. …”
Get full text

Implementing peer support work in mental health care in Germany: The methodological framework of the collaborative, participatory, mixed‐methods study (ImpPeer‐Psy5) by Sebastian vonPeter, Ute Maria Kraemer, Lauren Cubellis, Georgia Fehler, Guillermo Ruiz‐Pérez, Daniela Schmidt, Jenny Ziegenhagen, Madeleine Kuesel, Susanne Ackers, Candelaria Mahlke, Lena Nugent, Imke Heuer

“…The choice of a collaborative or participatory methodological framework is advised to better align research questions and procedures to the specific needs and challenges of PSWs and other stakeholders concerned with PSW implementation. …”
Get full text

New unloading criterion for enhancing multi-stage triaxial tests based on radial strain gradient by Guodong Jin, Shujath Ali Syed, Héctor José González-Pérez, Hyung Tae Kwak, Ali Abdullah Yousef, Ali Abdullah Al Dhamen

“…Failure envelopes from the RSG criterion match well with those from single-stage tests. A practical procedure is recommended to use the RSG criterion: an unconfined compression or single-stage test is first conducted to determine the RSG at peak stress for one sample, the unloading point is then selected to be a value close to the RSG at peak stress, and the multi-stage test is finally performed on another sample using the pre-selected RSG unloading criterion. …”
Get full text

EFFECTIVENESS OF UNIPOLAR RADIOFREQUENCY SURGICAL ABLATION FOR ATRIAL FIBRILLATION by Adriano Meneghini, Marcelo Rodrigues Bacci, Neif Murad, Antonio Carlos Palandri Chagas, José Honório Palma, Luiz Carlos de Abreu, Victor E. Valenti, João Roberto Breda

“…All cases were diagnosed at least 12 months before the procedure and the group consisted of 15 (42,8%) male and 20 female (51,2%) patients, aged 25-78 years (52,23±12,82).Results. …”
Get full text

Knowledge, Attitudes, and Practices related to COVID-19 among People in Kurdistan Region of Iraq: A Cross-Sectional Survey by Shalaw Faris Ahmed, Dara Abdulla Al-Banna, Jamal Kareem Shakor, Sairan Khurshed Nariman, Ari Ahmed Taha

“…Majority of respondents (92.9%) were optimistic that the government could take necessary procedures to reduce the risks of Coronaviruses infection. …”
Get full text

The value of preoperative RDW for post-pancreatectomy haemorrhage and surgical prognosis in patients with pancreatic cancer: a retrospective study by Ting Niu, Yueying Wang, Liangliang Lu, Jialin Li, Tianhua Cheng, Yuanqiang Dai

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor, and only some patients can receive surgical treatment. Complex surgical procedures combined with various postoperative complications seriously affect the prognosis of patients. …”
Get full text