Association Between the Effectiveness and Magnitude of Foot Microcirculation Assessed by Radionuclide Angiography and One Year Limb Outcomes in Patients with Chronic Limb Threateni... by Takuya Hashimoto, Yoshitaka Kumakura, Kenichi Ichikawa, Satoshi Yamamoto, Takashi Endo, Masaya Sano, Osamu Sato, Juno Deguchi

“…The lower limbs of 13 patients diagnosed with CLTI were evaluated by radionuclide (RN) angiography with 99mTc-tetrofosmin two weeks after revascularisation or non-revascularisation procedures. Novel parameters (pedal transit time and peak pedal count) were derived by processing the time–activity curves of the detected tracers in each region of interest in the limbs. …”
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Understanding community pharmacists’ intentions to report adverse drug reactions in Saudi Arabia: a theory of planned behavior analysis by Fahad T. Alsulami, Yousef Saeed Alqarni, Wadia Saad Alruqayb, Mohammed S. Alharthi, Mohammad S. Alzahrani, Majed A. Algarni, Musaad M. Althobaiti, Saad Mohammed Almalki, Nawaf Abid Altowarqi, Hussain Ali Mathkur, Anas Muslih Althumali, Ayman Mohammed Alharthi, Haifa Abdulrahman Fadil, Adel A. Altowairqi, Mubarak S. Alharthi

“…Pharmacists who were non-Saudi, aware of the NPC and its procedures, and trained in ADR reporting demonstrated significantly higher intentions to report (p < 0.05). …”
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Left‐Digit Bias in Serum Creatinine Levels and Contrast Administration: A Nationwide Cohort Study Using a Japanese Percutaneous Coronary Intervention Registry by Takahiro Suzuki, Yuichiro Mori, John A. Spertus, Nobuhiro Ikemura, Atsushi Mizuno, Taku Asano, Yasufumi Kijima, Daisuke Yoneoka, Hideki Wada, Kyohei Yamaji, Tetsuya Amano, Ken Kozuma, Shun Kohsaka

“…Results Among 735 696 PCI procedures, the median contrast volume was 117 mL (interquartile range 85–157 mL). …”
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A prospective study of a training program for bronchial sleeve resection using operable 3-dimensional modelsCentral MessagePerspective by Kohei Hashimoto, MD, PhD, Daiki Kato, MD, PhD, Junji Ichinose, MD, PhD, Yosuke Matsuura, MD, PhD, Masayuki Nakao, MD, PhD, Sakae Okumura, MD, Haruhiko Kondo, MD, PhD, Takashi Ohtsuka, MD, PhD, Mingyon Mun, MD, PhD

“…Their right upper lobe sleeve reconstruction procedures were scored by 2 senior surgeons in a blinded fashion on a 5-point Likert scale on the following: airway wall tear, reapplied ligatures, reapplied needles, needle entry and exit, anastomotic bite, and caliber adjustment (full score: 30). …”
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A novel optimized silver nitrate staining method for visualizing the osteocyte lacuno-canalicular system by Jinlian Wu, Jinlian Wu, Chunchun Xue, Qiang Li, Hongjin Wu, Jie Zhang, Chenglong Wang, Weiwei Dai, Libo Wang

“…However, variability in reagent concentrations and types, along with inconsistent staining procedures, have limited the broader application of this method in osteocyte research. …”
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Impact of obesity on clinical outcomes in patients with high-risk pulmonary embolism: A comparative analysis by Ziv Shachar, Marlon V. Gatuz, Adam Folman, Maguli S. Barel, Rami Abu-Fanne, Dmitry Abramov, Mamas A. Mamas, Ariel Roguin, Ofer Kobo

“…We compared baseline characteristics, in-hospital procedures, and outcomes among these groups. Multivariable logistic regression models assessed the relationship between obesity levels and in-hospital outcomes. …”
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Enhancing skull base tumor management: the combination of 3D printing technology and endoscopic surgical techniques by Xiao Li, Peng Gao, Angsi Liu, Fuxing Zuo, Ke Hu, Yang Wang, Haiyan Li, Jianxin Kong, Xueji Li

“…Abstract Object 3D printing technology stands as a transformative force in medicine, offering outstanding precision and personalization in surgical planning, patient education, and the development of anatomical models for complex procedures. This paper aims to explore the application experiences of 3D printing in endoscopic skull base tumor surgeries, evaluating the impact and effectiveness of 3D-printed models in enhancing both surgical simulations and anatomical learning in the field of neurosurgery for skull base tumors. …”
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Cartilage thickness can be accurately measured intraoperatively in total knee arthroplasty: A step further in calipered kinematic alignment by Giancarlo Giurazza, Stefano Campi, Michael T. Hirschmann, Edoardo Franceschetti, Andrea Tanzilli, Pietro Gregori, Michele Paciotti, Biagio Zampogna, Rocco Papalia

“…Abstract Introduction Kinematic alignment (KA) in total knee arthroplasty (TKA) is by definition a pure femoral resurfacing procedure aiming to restore the individual prearthritic anatomy. …”
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Case Report: Late-onset primary hemophagocytic lymphohistiocytosis leading to the diagnosis of Griscelli syndrome type 2 in a young woman with phenotypically inapparent partial alb... by Johanna Rausch, Johanna Rausch, Stephanie Herold, Simone Liebhäuser, Yagmur Bülbül, Edite Antunes Ferreira, Till Wenz, Kevin Jan Legscha, Kevin Jan Legscha, Matthias Bros, Florian Butsch, Oliver Kriege, Klaus Warnatz, Klaus Warnatz, Miriam Groß, Miriam Groß, Kai Lehmberg, Helena Clara Lichtenfeld, Paul La Rosée, Markus Philipp Radsak, Markus Philipp Radsak, Matthias Theobald, Matthias Theobald, Matthias Theobald, Hakim Echchannaoui, Hakim Echchannaoui, Markus Munder, Markus Munder, Markus Munder

“…After two severe episodes within only a few months, she eventually received an allogeneic HSCT and has not experienced further HLH episodes for now more than 3 years after the HSCT procedure. This case should raise awareness for the possibility of initial manifestation of primary, genetically-determined HLH even in adult patients.…”
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Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development by Yuenshan Sammi Wong, Yuenshan Sammi Wong, Ho Ming Luk, Ho Chung Yau, Lap Ming Wong, Sarah Wing Yiu Poon, Joanna Yuet Ling Tung, Yuk Him Tam, Yuk Him Tam

“…A total of 20/21 patients underwent one or more surgical procedures including hypospadias repair (n = 10), gonadectomy (n = 11), gonadal biopsy (n = 4), hernia repair (n = 4), orchidopexy (n = 1), and feminizing genitoplasty (n = 1). …”
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Surgical implants in animal models for male and female infertility: A translational approach by S. Bharath, A.S. Vickram, B. Bhavani Sowndharya, C. Prasanth, D. Jenila Rani, G. Gulothungan, Hitesh Chopra, Tabarak Malik

“…The investigation included a comprehensive review of advancements in microsurgical techniques, biological implants, and robotic-assisted procedures that enhance the precision and effectiveness of implant placement. …”
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Post-pericardiectomy ECMO for constrictive pericarditis: a case series and literature review by Bin Jia, Shujie Yan, Yong Luo, Jian Cheng, Jie Cheng, Junjie Fei, Yushuang Gao, Xiao Liao, Luyu Bian, Jian Wang, Yuan Teng, Gang Liu, Lanying Gao, Bingyang Ji

“…All the patients undertwent pericardiectomy via median sternotomy, and 5 patients underwent concomitant valve procedures. One patient failed to wean from the cardiopulmonary bypass (CPB) and was transferred to femoral VA-ECMO. …”
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An innovative resection of giant neurofibromas by Zhichao Wang, Xuan Yu, Yihui Gu, Wei Wang, Chengjiang Wei, Bin Gu, Jun Yang, Qingfeng Li

“…Results: Among 456 patients with 494 PNF who underwent surgical resection, we categorized the procedures into median, large, and giant PNF subgroups. …”
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Emerging cytokines contribute to the clinical manifestation of carotid artery plaque formation and stability in patients with diabetes by Zhongqing Xu, James Healy, Wenhui Dong, JingJing Ding, Xiaoyi Shen, Xianzhen Feng, Jun Zhou, Rajesh Puranik, Brett D. Hambly, Shisan Bao

“…Carotid plaque samples (n = 50) were collected from endarterectomy procedures and categorised as stable (asymptomatic, n = 25) or unstable (symptomatic, n = 25) according to AHA criteria. …”
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Molecular genetic markers of breast cancer: current advances in understanding the etiology, prognostic value, and therapeutic opportunities by M. M. Omarov, V. V. Trusova, L. M. Agabekyan, I. R. Gaziev, Z. M. Alibekova, L. A. Aivazyan, E. A. Safarova, A. M. Adzhigulova, A. A. Darmilova, E. K. Khanmukhometova, I. R. Vanova, V. I. Pigareva

“…Despite substantial research advances, the accessibility of molecular diagnostics, standardization of procedures, and integration of innovative technologies into clinical practice remain pressing issues. …”
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Factors Influencing Nerinetide Effect on Clinical Outcome in Patients Without Alteplase Treatment in the ESCAPE-NA1 Trial by Mayank Goyal, Bijoy K. Menon, Johanna Ospel, Mohammed Almekhlafi, Charlotte Zerna, Raul Nogueira, Ryan McTaggart, Andrew M. Demchuk, Alexandre Y. Poppe, Brian Buck, Kathy Heard, Manish Joshi, Diogo Haussen, Shawna Cutting, Shelagh B. Coutts, Daniel Roy, Jeremy L. Rempel, Thalia S. Field, Dar Dowlatshahi, Brian van Adel, Richard Swartz, Ruchir Shah, Eric Sauvageau, Volker Puetz, Frank L. Silver, Bruce Campbell, René Chapot, Michael Tymianski, Michael D. Hill, on Behalf of the ESCAPE-NA1 Investigators

“…We constructed two multivariable models using variables known prior to randomization and variables known immediately post-EVT procedure to provide adjusted estimates of effect. …”
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Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis by Fanjie Lin, Ken Lin, Donglei Li, Weiguo Kong, Jiayu Zhuang, Wei He, Xinguang Wei, Tianchi Xiao, Hao Zu, Zili Zhang, Wenju Lu

“…In addition, a machine learning-based integrative procedure for constructing a concordance plasma cells-related gene signature (PCRGS) was developed. …”
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Development and validation of a nomogram prediction model for perioperative deep vein thrombosis risk in arthroplasty: a retrospective study by Wenming Yang, Wenming Yang, Qitai Lin, Qitai Lin, Zehao Li, Zehao Li, Chuanjie Shan, Chuanjie Shan, Xiaoyu Cheng, Yugang Xing, Yugang Xing, Yongsheng Ma, Yongsheng Ma, Yang Liu, Yang Liu, Meiming Li, Meiming Li, Ruifeng Liang, Wangping Duan, Wangping Duan, Wangping Duan, Pengcui Li, Pengcui Li, Xiaochun Wei, Xiaochun Wei

“…Patients’ demographic and perioperative laboratory data were collected and divided into training (73.8%) and validation sets (26.2%) based on order of procedure date. Variables were screened from the training set using the Least Absolute Shrinkage and Selection Operator (LASSO) regression; a nomogram was constructed after multivariate logistic regression. …”
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Mucosal barrier injury as an independent risk factor for laboratory-confirmed bloodstream infection in patients with hematological malignancies: a real-world study by Mengna Liu, Xi Jiang, Yingqi Pi, Mingming Chen, Xiuqin Ren, Xinlu Dai, Yixian Wu, Yanrong Guo, Xinyi Zhang, Xiaoying Xie, Zhaofan Luo

“…Abstract Background Hematological malignancy (HM) patients are at high risk of bloodstream infections (BSIs) due to chemotherapy-induced mucosal barrier injury (MBI), invasive procedures, and prolonged antimicrobial exposure. While conventional nosocomial infection paradigms emphasize catheter-related biofilms, emerging evidence highlights the role of disrupted oral/gut microbiomes in bacterial translocation. …”
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Comparison of perioperative outcomes of open (CUSA) versus laparoscopic (LOTUS) major hepatectomy – revisited. First evaluation of efficacy and safety of AEON™ stapler by Affan Iqbal, Minas Baltatzis, Minas Baltatzis, Panagiotis Stathakis, Jenifer Barrie, Ajith Kumar Siriwardena, Ajith Kumar Siriwardena, Saurabh Jamdar, Aali Jan Sheen, Aali Jan Sheen

“…The LOTUS™ ultrasonic energy device was used for transection in laparoscopic cases, whereas CUSA was used in open procedures. AEON was introduced in 2021 and compared with the previously used stapler.ResultsThe initial sample of 116 patients was narrowed to 86 after applying 1:1 matching. …”
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