Comparison of clinical nasal endoscopy, optical biopsy, and artificial intelligence in early diagnosis and treatment planning in laryngeal cancer: a prospective observational study by Ruifang Hu, Xianping Liu, Yong Zhang, Clement Arthur, Dongguang Qin

“…Optical biopsy methods provided better visualization of lesions; however, not all patients had all three modalities in a single procedure. Diagnostic delay was shortened with a median time of 15 to 7 days (<0.001). …”
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Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study by Carolyn E Schwartz, ScD, Katrina Borowiec, MA, Bruce D Rapkin, PhD, Joel A Finkelstein, MD, MSc, FRCS(C), Tai Sutherland, BA, Olivia B Caan, BA, MS, Richard L Skolasky, ScD

“…The Benjamini-Hochberg procedure reduced the false-discovery rate. Results: The OUD risk classification was validated. …”
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EFFECTIVENESS AND SAFETY OF FAVIPIRAVIR INFUSION IN PATIENTS HOSPITALIZED WITH COVID-19 by L. A. Balykova, K. Ya. Zaslavskaya, V. F. Pavelkina, N. A. Pyataev, N. M. Selezneva, N. V. Kirichenko, A. Yu. Ivanova, G. V. Rodoman, K. B. Kolontarev, K. S. Skrupsky, E. N. Simakina, O. A. Mubarakshina, A. V. Taganov, D. Yu. Pushkar

“…An open, randomized, multicenter comparative study was conducted in 6 research centers in the Russian Federation to evaluate the efficacy and safety of favipiravir, a lyophilisate for the preparation of a concentrate for the infusion solution administrated to the patients hospitalized with COVID-19. Screening procedures and randomization were completed in 217 patients, 209 of which had completed the study in accordance with the protocol.Results. …”
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Surgical Antibiotic Prophylaxis Used in A University Clinics Hospital and Antibiotic Costs: A 3-year Survey by Vianney N. Ntabaza, PhD, Antonelle Pardo, PhD, Amandine Nachtergael, PhD, Julien Bamps, MSc, Salvius A. Bakari, PhD, Pierre Duez, PhD, Stephanie Patris, PhD, Byanga Kahumba, PhD

“…Results: Shortcomings in registered data and the application of exclusion criteria allowed to include only 256 of the 977 retrospective procedures recorded during this period, with around 50% of the cases in 2019. …”
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Validation of an Automated High-Throughput Multiplex Real-Time PCR Assay for Detection of Enteric Protozoa by Rachel Lau, Jason Kwan, Kimberley Marks-Beaubrun, Ruben Cudiamat, Min Qun Ellen Chen, Krista Orejana, Filip Ralevski, Andrea K. Boggild

“…<b>Background</b>: Microscopy is the conventional method for the identification of gastrointestinal parasitic pathogens in fecal specimens; however, it presents numerous challenges, including high technical expertise burden, multiple staining procedures, and prolonged turnaround time. Molecular methods provide higher throughput and potentially higher sensitivity and specificity. …”
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Racial/Ethnic Disparities in Lung Cancer Surgery Outcomes in the USA by Ivana Vasic, Kian C. Banks, Julia Wei, Leyda Marrero Morales, Zeuz A. Islas, Nathan J. Alcasid, Cynthia Susai, Angela Sun, Katemanee Burapachaisri, Ashish R. Patel, Simon K. Ashiku, Jeffrey B. Velotta

“…Multivariable logistic and linear models adjusted for age, sex, body mass index (BMI), Charlson Comorbidity Index scores, procedure approach, neighborhood deprivation index (NDI), cancer stage, receipt of adjuvant chemotherapy, and insurance. …”
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4th and 5th seasons of the Nubian Expedition of the Anuchin Research Institute and Museum of Anthropology, Lomonosov Moscow State University at the Sites of Deraheib and Onib (the... by Krol Alexei A., Simonenko Anton A., Tsyganov Andrey N., Petrova Natalia Yu., Ershova Victoria B., Kandinov Mikhail N., Mazei Natalia G., Pastukhova Yuliya A., Chulei Artemii D., Mazei Yuri A.

“…Sample preparation and analysis were carried out following the standard procedures. Results and Discussion. Analysis of the finds made at the sites indicates that the entire Wadi al-Allaqi region from the Red Sea Mountains to the Nile Valley was inhabited during the Neolithic period. …”
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Assessment of Circulating Tumor Cells in Colorectal Cancer as an Adjunctive Non-invasive Diagnostic Method by Saskia Aziza Nursyirwan, Murdani Abdullah, Andri Sanityoso Sulaiman, Ikhwan Rinaldi, Dadang Makmun, Marcellus Simadibrata, Dimas Ramadhian Noor, Agustinus Wiraatmadja, Wifanto Saditya Jeo, Nur Rahadiani, Diah Rini Handjari, Hamzah Shatri

“…Biopsy remains the gold standard for CRC diagnosis, but invasive testing may not be preferred as an initial diagnostic procedure. Therefore, alternative non-invasive approaches are needed. …”
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Hyperspectral abdominal laparoscopy with real-time quantitative tissue oxygenation imaging: a live porcine study by Oscar MacCormac, Oscar MacCormac, Conor C. Horgan, Conor C. Horgan, Dale Waterhouse, Dale Waterhouse, Philip Noonan, Philip Noonan, Mirek Janatka, Mirek Janatka, Richard Miles, Richard Miles, Jaco Jacobs, Cameron Dockerill, Cameron Dockerill, Théo Trotouin, Théo Trotouin, Alexis Schizas, Barbara Seeliger, Barbara Seeliger, Barbara Seeliger, Sebastien Ourselin, Sebastien Ourselin, Michael Ebner, Michael Ebner, Tom Vercauteren, Tom Vercauteren, Jonathan Shapey, Jonathan Shapey, Jonathan Shapey

“…Real-time tissue oxygenation maps were shown to visually correlate with ICG-FA.ConclusionThe HSS can guide laparoscopic surgical procedures whilst providing visual and quantitative tissue oxygenation information in a live animal model. …”
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Intrauterine Adhesions and Asherman Syndrome: A Retrospective Dive into Predictive Risk Factors, Diagnosis, and Surgical Perspectives by Loredana Maria Toma, Demetra Socolov, Daniela Matei, Sorana Anton, Raluca Balan, Emil Anton, Roxana Covali, Mihaela Tirnovanu, Handra Elicona, Theodor Pantilimonescu, Razvan Socolov

“…<b>Results and discussions</b>: Women over 35 years are more likely to develop these conditions due to prior gynaecological procedures which are often associated with fertility issues. …”
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Validation of an AI-enabled exome/transcriptome liquid biopsy platform for early detection, MRD, disease monitoring, and therapy selection for solid tumors by J. Abraham, V. Domenyuk, N. Perdigones, S. Klimov, S. Antani, T. Yoshino, E. I. Heath, E. Lou, S. V. Liu, J. L. Marshall, W. S. El-Deiry, A. F. Shields, M. F. Dietrich, Y. Nakamura, T. Fujisawa, G. D. Demetri, A. Barker, J. Xiu, D. A. Sacchetti, S. Stahl, R. Hahn-Lowry, A. Stark, J. Swensen, G. Poste, D. D. Halbert, M. Oberley, M. Radovich, G. W. Sledge, David B. Spetzler

“…The diagnostic first-line procedure for tissue of origin was determined for 8 categories with a top-3 accuracy of 85% for stage I and II cancers. …”
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Enhancing landslide disaster prediction by evaluating non landslide area sampling in machine learning models for Spiti Valley India by Devraj Dhakal, Kanwarpreet Singh, Kennedy C. Onyelowe, Steven Alejandro Salazar Cazco, Abhishek Sharma, Nassir Alarifi, Fakhrul Islam, Randeep, Krishna Prakash Arunachalam, Youssef M. Youssef

“…Advanced machine learning and new sampling procedures may improve LSM accuracy and reliability in high-risk zones. …”
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Automatic Detection of Slow Conducting Channels during Substrate Ablation of Scar-Related Ventricular Arrhythmias by Alejandro Alcaine, Beatriz Jáuregui, David Soto-Iglesias, Juan Acosta, Diego Penela, Juan Fernández-Armenta, Markus Linhart, David Andreu, Lluís Mont, Pablo Laguna, Oscar Camara, Juan Pablo Martínez, Antonio Berruezo

“…Voltage mapping allows identifying the arrhythmogenic substrate during scar-related ventricular arrhythmia (VA) ablation procedures. Slow conducting channels (SCCs), defined by the presence of electrogram (EGM) signals with delayed components (EGM-DC), are responsible for sustaining VAs and constitute potential ablation targets. …”
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The basal cisternostomy for management of severe traumatic brain injury: A retrospective study by Tangrui Han, Zhiqiang Jia, Xiaokai Zhang, Hao Wu, Qiang Li, Shiqi Cheng, Yan Zhang, Yonghong Wang

“…Basal cisternostomy has been shown to be highly effective as an alternative procedure to decompressive craniectomy. Methods: We conducted a retrospective cohort of patients who received surgery for severe TBI between January 2019 and March 2023. …”
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Robot-assisted Management of Complex Ureteral Stenosis in Kidney Transplant Patients: Multicenter Case Series and Description of Surgical Techniques by Joris Vangeneugden, Federico Lavagno, Camille Berquin, Liesbeth Desender, Steven Van Laecke, Marco Oderda, Marco Allasia, Alberto Breda, Charles Van Praet, Karel Decaestecker, Paolo Gontero

“…Methods and surgical procedure: We included 29 renal transplant patients who suffered from ureteral stenosis in whom ureteral reconstruction was performed at three referral centers from November 2019 to March 2024. …”
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Pancreatic surgery is safe in elderly patients with PDAC by Yueming Zhang, Siyang Han, Yaolin Xu, Liang Liu, Wenchuan Wu, Lei Zhang, chenye Shi, Chao Song, Dansong Wang, Wenhui Lou

“…Furthermore, poorer inflammatory-nutritional status was frequently associated with more complex surgical procedures, including longer surgical durations, greater intraoperative reported blood loss, and a higher number of resected lymph nodes, particularly in non-elderly patients. …”
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Establishment of <i>Agrobacterium</i>-Mediated Transient Transformation System in Sunflower by Fangyuan Chen, Lai Wang, Qixiu Huang, Run Jiang, Wenhui Li, Xianfei Hou, Zihan Tan, Zhonghua Lei, Qiang Li, Youling Zeng

“…In this study, we established an efficient transient expression transformation system for sunflower using three methods: <i>Agrobacterium</i>-mediated infiltration, injection, and ultrasonic-vacuum. The detailed procedures were as follows: <i>Agrobacterium</i> GV3101 carrying a <i>GUS</i> reporter gene on the pBI121 vector with an OD₆₀₀ of 0.8 as the bacterial suspension and 0.02% Silwet L-77 as the surfactant were utilized in all three approaches. …”
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Study of the immunological efficacy and safety of a candidate vaccine against Lassa hemorrhagic fever by O. Popova, O. V. Zubkova, T. A. Ozharovskaia, D. I. Zrelkin, D. V. Voronina, P. P. Goldovskaya, V. Yu. Kan, I. V. Dolzhikova, A. V. Kovyrshina, D. M. Grousova, I. A. Ermolova, D. V. Shcheblyakov, D. Yu. Logunov, A. L. Gintsburg

“…Standard genetic engineering techniques, molecular biology techniques, virological methods, and animal testing procedures were used in the course of the study. A combined vector candidate vaccine for the prevention of Lassa hemorrhagic fever has been designed and characterized. …”
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Surgical Outcomes of Video‐Assisted Thoracic Surgery Combined With Computed Tomography‐Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground‐Glass Opacities: A 5‐... by Bin Huang, Chuanfei Zhan, Pengcheng Yu, Yifan Xu, Muhammad Zunair Bhatti, TianMing Chen, WenDa Yin, Zhifei Ma, Chi Su, Zhongqiu Wang, Dongjie Feng, Tian Shen, Xiaokang Shen, Dongqing Lu, Lin Zheng, Shilin Chen

“…The outcomes assessed in this study included the feasibility and safety profile of the combined procedure, as well as event‐free survival (EFS), local progression‐free survival (LPFS), and overall survival (OS). …”
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Radioresistant mouse pheochromocytoma cell lines by Sandy Lemm, Sandy Lemm, Marcel Gebhardt, Thomas Groß, Susan Richter, Susan Richter, Martin Ullrich, Jens Pietzsch, Jens Pietzsch

“…However, the underlying mechanisms of radioresistance in PCC/PGL remain largely unknown and appropriate models are missing.MethodsTwo genetically modified mouse pheochromocytoma (MPC) cell lines, one positive and one negative for hypoxia-inducible factor 2α expression (MPC+HIF-2α and MPC+EV [empty vector], respectively), were X-ray-conditioned through fractionated irradiation at sublethal doses. Two procedures were tested: one allowed for recovery between each irradiation step (recIR), while the other demanded daily irradiation (dayIR). …”
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