Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway by Nesrine Ebrahim, Hajir A. Al Saihati, Zahraa Alali, Sabry Younis Mohamed Mahmoud, Ali A. Rabaan, Arigue A. Dessouky, Rabab F. Salim, Ashraf A. Shamaa, Ahmed N. Abdallah, Nehal M. Elsherbiny, Gamal Othman, Abdelnaser A. Badawy, Gianpiero Di Leva, Omnia A. Badr

“…Western blotting was employed to evaluate protein expression. All procedures adhered to ethical and biosafety guidelines. …”
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Single-Incision paediatric laparoscopy-Assisted for the treatment of postnecrotizing enterocolitis colonic strictures: a single-centre retrospective study by Aohua Song, Xunfeng Li, Xiao Xiang, Wei Feng, Zhenhua Guo

“…Conclusion The SIPL procedure for the treatment of post-NEC colonic strictures demonstrates an efficacy and safety comparable to those of OS and also offers potential cosmetic benefits.…”
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AI-Based Noise-Reduction Filter for Whole-Body Planar Bone Scintigraphy Reliably Improves Low-Count Images by Csaba Csikos, Sándor Barna, Ákos Kovács, Péter Czina, Ádám Budai, Melinda Szoliková, Iván Gábor Nagy, Borbála Husztik, Gábor Kiszler, Ildikó Garai

“…The implementation of this filter in routine diagnostic procedures reliably improves diagnostic confidence in low-count images and elicits a reduction in the administered dose or acquisition time by a minimum of 50% relative to the original dose or acquisition time.…”
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Segmental Pulse Volume Recordings at the Forefoot Level as a Valuable Diagnostic Tool for Detection of Peripheral Arterial Disease in the Diabetic Foot Syndrome by Andreas Nützel, Lilly Juliane Undine Reik, Maximilian Hamberger, Christian Lottspeich, Sinan Deniz, Anja Löw, Holger Schneider, Hans Polzer, Sebastian Baumbach, Michael Czihal

“…<b>Patients and methods:</b> Patients with DFS who underwent invasive angiography between 01/2020 and 11/2024 and had corresponding PVRs performed within 30 days prior to the procedure were included. DFS was classified according to the Wagner–Armstrong classification. …”
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Incidence and Prevention of Vaginal Cuff Dehiscence After Laparoscopic and Robotic Hysterectomy in Benign Conditions: An Updated Systematic Review and Meta-Analysis by Pier Carlo Zorzato, Riccardo Vizza, Simone Garzon, Mariachiara Bosco, Anna Festi, Alberta Ricci, Irene Porcari, Giacomo Corrado, Rosa Maria Laterza, Stefano Uccella

“…With the rising frequency of this procedure, it is crucial to continuously evaluate VCD incidence, risk factors, and prevention strategies. …”
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Metabolomic profiles differentiate between porto-sinusoidal vascular disorder, cirrhosis, and healthy individuals by Georg Semmler, Oleksandr Petrenko, Juanjo Jose Lozano, Sarah Shalaby, Juan I. Sánchez-Avila, Nara Marella, Thomas Hannich, Katharina Wöran, Lorenz Balcar, Benedikt Simbrunner, Katharina Lampichler, Behrang Mozayani, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Juan-Carlos García-Pagán, Bernhard Scheiner

“…These findings could enable earlier and non-invasive diagnosis of PSVD, potentially reducing reliance on invasive procedures like liver biopsy and guiding diagnostic pathways.…”
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Strategies and Techniques for Ileourethral Approximation During Robotic Intracorporeal Neobladder Reconstruction: An International Survey and Video Collection, in Collaboration wit... by Maria Chiara Sighinolfi, Simone Assumma, Peter Wiklund, Richard Gaston, Andrea Minervini, Alex Mottrie, Reza Mehrazin, Abdullah Erdem Canda, Enrico Panio, Filippo Gavi, Luca Sarchi, Tommaso Calcagnile, Filippo Turri, Fabrizio Di Maida, Luca Lambertini, Hubert Jhon, Rafael Coelho, Abolfazi Hosseini, Kris Maes, Anup Kumar, Sudhir Kumar Rawal, T.B. Yuvaraja, Giovanni Enrico Cacciamani, Antonio Celia, Costantino Leonardo, Francesco Greco, Roberto Falabella, Filippo Annino, Antonio Galfano, Angelo Porreca, Alessandro Crestani, Paolo Umari, Riccardo Bertolo, Alessandro Antonelli, Rocco Papalia, Ugo Falagario, Riccardo Schiavina, John Sfakianos, Neerja Tillu, Carl Wijburg, Vincenzo Tondolo, Sergio Alfieri, Alberto Breda, Giorgia Gaia, Stefano Terzoni, Marcio Covas Moschovas, Vipul Patel, Bernardo Rocco

“…Methods and surgical procedure: This is a cross-sectional study in collaboration with the European Association of Urology Robotic Urology Section (ERUS) Scientific Working Group that evaluates strategies for ileourethral approximation and anastomosis from surgeons performing RARC with an intracorporeal neobladder. …”
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Bioassay-Guided Isolation of <i>cis</i>-Clerodane Diterpenoids and Monoglycerides from the Leaves of <i>Solidago gigantea</i> and Their Antimicrobial Activities by Márton Baglyas, Péter G. Ott, Zoltán Bozsó, Ildikó Schwarczinger, József Bakonyi, Dénes Dlauchy, András Darcsi, Szilárd Varga, Ágnes M. Móricz

“…The bioassay-guided isolation procedure included thin-layer chromatography (TLC) coupled with a <i>Bacillus subtilis</i> antibacterial assay, preparative flash column chromatography, and TLC–mass spectrometry (MS). …”
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Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate predicti... by Lin Yang, Guangyu Lu, Haiqing Diao, Yang Zhang, Zhiyao Wang, Xiaoguang Liu, Qiang Ma, Hailong Yu, Yuping Li

“…This model can provide clinicians with a tool for prevention and management of MDRO infections in NICU patients with HAP.IMPORTANCEPatients with hospital-acquired pneumonia (HAP) in the neuro-intensive care unit (NICU) are at a high risk of developing multidrug-resistant organism (MDRO) infections owing to complex conditions, critical illness, and frequent invasive procedures. However, studies focused on constructing prediction models for assessing the risk of MDRO infections in neurocritically ill patients with HAP are lacking at present. …”
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Do Meta‐Analyses of Total Hip Arthroplasty Produce Reliable Results? A Systematic Review and Meta‐Epidemiological Study of Statistical Methods by Nikolai Ramadanov, Maximilian Voss, Radharani Michelle Diallo, Jonathan Lettner, Hassan Tarek Hakam, Robert Prill, Roland Becker, Robert Hable

“…ABSTRACT Background Total hip arthroplasty (THA) is a highly successful orthopedic procedure, with numerous meta‐analyses published to optimize its outcomes. …”
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THE RESULTS OF FUNCTIONING OF THE UNIFIED SYSTEM OF INDIVIDUAL DOSE CONTROL OF THE RUSSIAN FEDERATION CITIZENS BASED ON THE 2017 DATA by A. N. Barkovsky, R. R. Akhmatdinov, R. R. Akhmatdinov, N. K. Baryshkov, A. M. Biblin, A. A. Bratilova, V. E. Zhuravleva, T. A. Kormanovskaya, S. I. Kuvshinnikov, I. K. Romanovich, A. G. Sivenkov, O. E. Tutelyan, A. G. Tsovyanov

“…According to the No.3-DOZ data, more than 286 mln. X-ray procedures were conducted in the Russian Federation in 2017. …”
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Morphologic and Morphometric Analysis of Crista Galli for Gender Determination using Cone Beam Computed Tomography: A Cross-sectional Study by Vaishnavi Sawant, Amita Aditya, Radhika Nair, Neha Kulkarni, Alisha Fargade, Samata Parakh

“…Additionally, since the CG shows morphological variation, its meticulous examination before any interventional procedure in the anatomical region is essential.…”
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CURRENT LEVELS OF MEDICAL EXPOSURE IN RUSSIA by M. I. Balonov, V. Ju. Golikov, I. A. Zvonova, S. A. Kal’nickij, V. S. Repin, S. S. Sarycheva, L. A. Chipiga

“…In 2013 median effective dose of medical exposure per capita in Russia was 0.45 mSv and median dose per procedure was 0.25 mSv. The major contribution to collective dose of medical exposure was from computed tomography and radiography; the largest individual doses were caused by interventional radiology, computed X-Ray and nuclear medicine tomographic examinations. …”
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Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial by Ilaria Righi, Claudio Fenizia, Daria Trabattoni, Mario Nosotti, Mario Nosotti, Giacomo Grisorio, Claudia Vanetti, Claudia Vanetti, Sonia di Tella, Cristina Mocellin, Norma Fantini, Daniele Prati, Letizia Corinna Morlacchi, Valeria Rossetti, Francesco Blasi, Francesco Blasi, Mario Clerici, Mario Clerici, Lorenzo Paolo Rosso, Lorenzo Paolo Rosso

“…Primary endpoints included safety, assessed based on the incidence of adverse events, treatment-related toxicity, and procedure-related complication rates; and feasibility, evaluated through the completion rate of scheduled ECP sessions, patient tolerability, and treatment discontinuation rates. …”
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Randomized adaptive assessment of post COVID syndrome treatments (RAPID): a study protocol for a multicenter, randomized, controlled adaptive platform trial of treatment options fo... by Lisa Weipert, Ralph G. Telgmann, Gabriele Anton, Thomas Asendorf, Irina Chaplinskaja-Sobol, Sandra Ciesek, Oliver A. Cornely, Sonja Drescher, Carsten Finke, Tim Friede, Julia Groth, Sabine Hanß, Wolfgang Hoffmann, Cynthia Huber, Thomas Illig, Monika Kraus, Dagmar Krefting, Sebastian Kuhn, Andreas Muehler, Matthias Nauck, Jens Schaller, Ann-Cathrin Schmidt, Georg Schmidt, Birgit Sawitzki, Ralf Tostmann, Heike Valentin, Maria Vehreschild

“…Patients are randomized at a 1:1 ratio to 45 mg/day vidofludimus calcium (22.5 mg for the first 7 days) or placebo during an initialization phase and thereafter using a response-adaptive randomization procedure. The trial includes a screening period of 7 days, a double-blind treatment period of 56 days and a follow-up period of 28 days. …”
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Prognostic model of the probability of successful extubation in the operating room after simultaneous kidney and pancreas transplantation by M. Sh. Khubutiya, M. V. Lebedev, N. K. Kuznetsova, A. M. Talyzin, A. G. Balkarov, N. S. Zhuravel, S. V. Zhuravel

“…Prolonged and highly traumatic surgery in recipients with severe initial pathology and tension(al) homeostasis doesn’t allow for safe procedure of early extubation in simultaneous kidney and pancreas transplantation (SKPT). …”
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Enhancing retention and quality of tissue stromal vascular fraction graft with globo H ceramide by Jing-Yan Cheng, Hui-Yun Cheng, Jung-Tung Hung, Gonzalo Mallarino Restrepo, Shih-Pin Chiou, Ling-Yi Shih, Alice L. Yu, Huang-Kai Kao, John Yu, Fu-Chan Wei

“…These findings support the potential clinical application of GHCer to enhance the stability and long-term outcomes of fat grafting procedures. Trial registration Not applicable. Clinical trial number Not applicable.…”
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Case Report: A case of occult insulinoma localized by [18F] FB (ePEG12)12-exendin-4 positron emission tomography with negative findings of selective arterial calcium stimulation te... by Kentaro Sakaki, Takaaki Murakami, Hiroyuki Fujimoto, Yoichi Shimizu, Kanae Kawai Miyake, Daisuke Otani, Shinya Otsuki, Hironori Shimizu, Kazuyuki Nagai, Takumi Nomura, Daisuke Yabe, Yuji Nakamoto, Nobuya Inagaki

“…Traditional imaging methods like computed tomography (CT) and magnetic resonance imaging (MRI) often fail to detect tumors, while more invasive procedures like endoscopic ultrasound tissue acquisition (EUS-TA) and the selective arterial calcium stimulation test (SACST), though informative, depend heavily on operator skill and may not always provide conclusive results. …”
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Patient perceptions of in‐hospital laboratory blood testing: A patient‐oriented and patient co‐designed qualitative study by Surakshya Pokharel, Zoha Khawaja, Jonathan Williams, Adnan Adil Mithwani, Kimberly Strain, Prachi Khanna, Anna Rychtera, Veronika Kiryanova, Karen Tang, Pamela Mathura, Chris Hylton, Anshula Ambasta

“…Patient engagement with laboratory testing in hospitals requires an empathetic healthcare team that provides clear communication regarding testing procedures, rationale and results, while considering patient preferences and offering opportunities for involvement. …”
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The ATLAS/NOA-29 study protocol: a phase III randomized controlled trial of anterior temporal lobectomy versus gross-total resection in newly-diagnosed temporal lobe glioblastoma by Matthias Schneider, Anna-Laura Potthoff, Yahya Ahmadipour, Valeri Borger, Hans Clusmann, Stephanie E. Combs, Marcus Czabanka, Lasse Dührsen, Nima Etminan, Thomas M. Freiman, Ruediger Gerlach, Florian Gessler, Frank A. Giordano, Eleni Gkika, Roland Goldbrunner, Erdem Güresir, Hussam Hamou, Peter Hau, Sebastian Ille, Max Jägersberg, Naureen Keric, Maryam Khaleghi-Ghadiri, Ralph König, Jürgen Konczalla, Harald Krenzlin, Sandro Krieg, Aaron Lawson McLean, Julian P. Layer, Jens Lehmberg, Vesna Malinova, Bernhard Meyer, Hanno S. Meyer, Dorothea Miller, Oliver Müller, Christian Musahl, Barbara E. F. Pregler, Ali Rashidi, Florian Ringel, Constantin Roder, Karl Rössler, Veit Rohde, I. Erol Sandalcioglu, Niklas Schäfer, Christina Schaub, Nils Ole Schmidt, Gerrit A. Schubert, Clemens Seidel, Corinna Seliger, Christian Senft, Julia Shawarba, Joachim Steinbach, Veit Stöcklein, Walter Stummer, Ulrich Sure, Ghazaleh Tabatabai, Marcos Tatagiba, Niklas Thon, Marco Timmer, Johannes Wach, Arthur Wagner, Christian Rainer Wirtz, Katharina Zeiler, Thomas Zeyen, Patrick Schuss, Rainer Surges, Christine Fuhrmann, Daniel Paech, Matthias Schmid, Yvonne Borck, Torsten Pietsch, Rafael Struck, Alexander Radbruch, Christoph Helmstaedter, Robert Németh, Ulrich Herrlinger, Hartmut Vatter

“…Anterior temporal lobectomy (ATL) is a standardized surgical procedure commonly performed in patients with pharmacoresistant temporal lobe epilepsy. …”
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