Comparison of the application value of contrast-enhanced ultrasound and contrast-enhanced CT in puncture biopsy of peripheral pulmonary lesions by Gang Wang, Ji-cheng Zhang, Zhi-hua Wang, Bo Gou, Xiao-lin Liu, Gang Liu, Jian Liu

“…The overarching objective is to establish robust clinical benchmarks that can guide evidence - based decision - making in the field of pulmonary interventional procedures.MethodsA comparison of 420 patients admitted to our hospital from January 2019 to December 2022 who underwent biopsy using two different guidance methods, including 196 cases in the CEUS-guided biopsy group and 224 cases in the CECT-guided biopsy group. …”
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A qualitative study on dietary behaviors and nutritional management needs of patients with active systemic lupus erythematosus (系统性红斑狼疮活动期患者饮食行为与营养管理需求的质性研究)... by SONG Weiting (宋炜婷), LI Yuwei (李雨蔚), QIAO Caicai (乔彩彩), WANG Sa (王飒), XUE Fei (薛菲), WANG Yuzhen (王玉珍), MIAO Huali (苗华丽)

“…It is recommended that clinical settings develop symptom-specific nutritional guidance tools and incorporate nutritional screening into routine assessment procedures. The aim is to establish a standardized path of assessment, education, and follow-up through multidisciplinary collaboration, and explore digital intervention strategies to enhance patient compliance. …”
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Advanced airway interventions for paediatric cardiac arrest: updated systematic review and meta-analysis by Jason Acworth, Jimena del Castillo, Elliott Acworth, Lokesh Tiwari, Jesus Lopez-Herce, Eric Lavonas, Laurie Morrison, Barnaby R. Scholefield

“…Placement of an advanced airway device may facilitate more effective resuscitation than bag-mask ventilation but requires more skilled personnel and the time taken to perform the procedure may interfere with other vital components of resuscitation. …”
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Key indicators for guiding tocilizumab therapy to prevent orbital decompression surgery in hormone-resistant dysthyroid optic neuropathy by Wenjun Shu, Wenjun Shu, Wenjun Shu, Wenjun Shu, Mingxu Yan, Mingxu Yan, Mingxu Yan, Mingxu Yan, Lu Gan, Lu Gan, Lu Gan, Lu Li, Hongyue Tao, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Jinghan Wang, Jinghan Wang, Jinghan Wang, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Xintong Lin, Xintong Lin, Xintong Lin, Haifeng Chen, Haifeng Chen, Haifeng Chen, Jie Guo, Jie Guo, Jie Guo, Kang Xue, Kang Xue, Kang Xue, Hongguang Cui, Heng Lou, Heng Lou, Heng Lou, Binbin Xu, Binbin Xu, Binbin Xu, Jinwei Cheng, Jinwei Cheng, Jinwei Cheng, Hongying Ye, Yiming Li, Jiang Qian, Jiang Qian, Jiang Qian, Rui Zhang, Rui Zhang, Rui Zhang, Ruiqi Ma, Ruiqi Ma, Ruiqi Ma, Fangfang Zeng

“…These indicators assist in the personalization of TCZ therapy and in the avoidance of unnecessary surgical procedures.…”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early by Mariangela Morelli, Francesca Lessi, Serena Barachini, Serena Barachini, Romano Liotti, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti

“…The number of MGMT gene promoter methylated tumors was higher in the responsive group, as expected, however, some non-methylated tumor cases turned out to be nevertheless responsive to TMZ, suggesting that our procedure could be synergistic with the classical MGMT methylation biomarker.ConclusionsFor the first time, FLIM-based metabolic imaging was used on live glioblastoma organoids. …”
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The use and impact of surveillance-based technology initiatives in inpatient and acute mental health settings: a systematic review by Jessica L. Griffiths, Katherine R. K. Saunders, Una Foye, Anna Greenburgh, Ciara Regan, Ruth E. Cooper, Rose Powell, Ellen Thomas, Geoff Brennan, Antonio Rojas-García, Brynmor Lloyd-Evans, Sonia Johnson, Alan Simpson

“…If they are to be implemented, all key stakeholders should be engaged in the development of policies, procedures and best practice guidance to regulate their use, prioritising patients’ perspectives.…”
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A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry by Johannes Leiner, Sebastian König, Anne Nitsche, Sven Hohenstein, Jana Nagel, Melchior Seyfarth, Henning Baberg, Alexander Lauten, Hans Neuser, Alexander Staudt, Jürgen Tebbenjohanns, René Andrié, Michael Niehaus, Markus W. Ferrari, Ralf Kuhlen, Andreas Bollmann

“…Data collection is based on a set of variables following recommendations of the International Consortium of Health Outcome Measurements (ICHOM) covering data on demographics, medical history, HF characteristics, medication, procedures, and patients' perceived health status via the collection of standardized PROs. …”
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Enhancing needle puncture detection using high-pass filtering and diffuse reflectance by Rachael L’Orsa, Rachael L’Orsa, Rachael L’Orsa, Rachael L’Orsa, Anupam Bisht, Linhui Yu, Kartikeya Murari, Kartikeya Murari, Kartikeya Murari, Garnette R. Sutherland, Garnette R. Sutherland, David T. Westwick, Katherine J. Kuchenbecker

“…Very high failure rates (up to 94.1%) have been reported for pre-hospital needle decompression, however, and the procedure can result in the accidental puncture of critical thoracic tissues because it is performed blind. …”
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Disproportionate impact of the COVID-19 pandemic on socially vulnerable communities: the case of Jane and Finch in Toronto, Ontario by Zahra Movahedi Nia, Zahra Movahedi Nia, Zahra Movahedi Nia, Cheryl Prescod, Michelle Westin, Patricia Perkins, Patricia Perkins, Mary Goitom, Mary Goitom, Kesha Fevrier, Kesha Fevrier, Sylvia Bawa, Sylvia Bawa, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong

“…ObjectiveThis work aims to study the disproportionate impact of the COVID-19 pandemic on the Jane and Finch community, one of the socially vulnerable neighborhoods in the Greater Toronto Area (GTA), Ontario, Canada, in terms of morbidity, mortality, and healthcare services.MethodologyA dataset provided by the Black Creek Community Health Centre (BCCHC), gathered from different health-related portals, covering various health statistics during COVID-19, namely, COVID-19 number of cases, hospitalizations, deaths, percentage of vaccination with one-, two-, and three-dose(s), Primary and Preventive Care (PPC) visits which include fecal and pap-smear cancer tests, and percentage of completed Imaging, Procedures, and Surgeries (IPS) which include the number of patients waiting for surgery were studied using statistical analysis. …”
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Acridocarpus smeathmannii root extracts inhibit human prostate and bladder smooth muscle contraction, porcine arterial vasoconstriction, and cytotoxicity of prostate stromal cells by Oluwafemi Ezekiel Kale, Sheng Hu, Claudia Huber, Felix Schierholz, Anna Ciotkowska, Alexander Tamalunas, Christian G. Stief, Wolfgang Eisenreich, Martin Hennenberg

“…In this study, we investigated the bioactivity-guided effects of Acridocarpus smeathmannii on smooth muscle contractility using human tissues obtained from radical prostatectomy and cystectomy procedures, as well as porcine coronary and interlobar arteries. …”
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Evaluation of grip strength in hook of hamate fractures treated with osteosynthesis. Is this surgical treatment necessary? by Claudia Lamas-Gómez, Laura Velasco-González, Aranzazu González-Osuna, Marta Almenara-Fernández, Luis Trigo-Lahoz, Xavier Aguilera-Roig

“…Objective: The aim of this study was to evaluate the outcomes of open reduction and internal fixation (ORIF) in hamate hook fractures and review the literature on this surgical procedure. Methods: We report the outcomes of ORIF of hamate hook fractures in 13 consecutive patients (12 men and 1 woman; mean age: 32 years (range, 22–48 years)). …”
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Cognitive Dysfunction in the Addictions (CDiA): protocol for a neuron-to-neighbourhood collaborative research program by Yuliya S. Nikolova, Yuliya S. Nikolova, Yuliya S. Nikolova, Anthony C. Ruocco, Anthony C. Ruocco, Anthony C. Ruocco, Anthony C. Ruocco, Daniel Felsky, Daniel Felsky, Daniel Felsky, Shannon Lange, Shannon Lange, Shannon Lange, Shannon Lange, Thomas D. Prevot, Thomas D. Prevot, Thomas D. Prevot, Erica Vieira, Erica Vieira, Daphne Voineskos, Daphne Voineskos, Jeffrey D. Wardell, Jeffrey D. Wardell, Jeffrey D. Wardell, Jeffrey D. Wardell, Daniel M. Blumberger, Daniel M. Blumberger, Kevan Clifford, Kevan Clifford, Ravinder Naik Dharavath, Philip Gerretsen, Philip Gerretsen, Ahmed N. Hassan, Ahmed N. Hassan, Ingrid M. Hope, Samantha H. Irwin, Sheila K. Jennings, Sheila K. Jennings, Bernard Le Foll, Bernard Le Foll, Osnat Melamed, Osnat Melamed, Josh Orson, Peter Pangarov, Leanne Quigley, Cayley Russell, Kevin Shield, Kevin Shield, Kevin Shield, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Ashley Smoke, Ashley Smoke, Victor Tang, Victor Tang, Victor Tang, Diana Valdes Cabrera, Diana Valdes Cabrera, Wei Wang, Samantha Wells, Samantha Wells, Samantha Wells, Rajith Wickramatunga, Etienne Sibille, Etienne Sibille, Etienne Sibille, Lena C. Quilty, Lena C. Quilty

“…Here, we introduce the design and procedures underlying Cognitive Dysfunction in the Addictions (CDiA), an integrative research program, which aims to fill these knowledge gaps and facilitate research discoveries to enhance treatments for people living with SUDs. …”
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Roles of private healthcare facilities in post-test counselling and referral for HIV services during antenatal care in South-West Nigeria by Henry Osaro Aisagbonhi, Yejide Olukemi Oseni, Mayowa Omolabake Odofin, Ezioma Anne Chukwu, Ukamaka Gladys Okafor, Ifeoluwa Silvanus Abiodun, Treasure Wariboko Obiajulu Okoye, Oluwadamilola Aminat Sadare, Eugenia Onwuchuluba Ebele, Esther Ametor Ajakaiye, Azeezat Abimbola Oyewande

“…Most facilities with screening services had written counselling procedures (64.7%), disclosed HIV status immediately (71.8%), and further supported patients with referral services (93.5%). …”
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Successful implementation of a risk assessment and mitigation program to control bovine digital dermatitis at the herd-level by Jim Weber, Marina Hillen, Torsten Seuberlich, Andreas Fürmann, Corinne Gurtner, Jens Becker, Claudia Syring, Maria Welham Ruiters, Maher Alsaaod, Lina Mazurek, Gertraud Schüpbach, Adrian Steiner

“…The results of this study show that the described BDD control measures can markedly reduce the within-herd prevalence of BDD. The proposed procedure might provide the basis for a nationwide BDD mitigation program that could be of importance also beyond national borders.…”
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Clinical characteristics and risk factors of chronic critical illness in children with sepsis by Lin Yang, Lin Yang, Na Zang, Na Zang, Cong Liu, Cong Liu, Ying Yang, Ying Yang, Kai Bing Pu, Kai Bing Pu, Li Ping Tan, Li Ping Tan, En Mei Liu, En Mei Liu

“…Secondary infections were also a prominent clinical feature of CCI cases.ConclusionsCCI in pediatric sepsis is associated with underlying respiratory diseases, trauma, elevated pSOFA scores, surgical procedures, prolonged mechanical ventilation and secondary infections. …”
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Separation of 1,3-Dimethylamylamine (1,3-DMAA) Stereoisomers, a Stimulant Drug, by Liquid Chromatography by Maria de Almeida Mexia de Almeida, Virgínia M. Gonçalves, Alexandra S. Maia, Diana Dias da Silva, Ricardo Jorge Dinis-Oliveira, Cláudia Ribeiro

“…Results: Preliminary results showed that the derivatization procedure allowed the formation of four 1,3-DMAA diastereomers confirmed by gas chromatography. …”
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Enhanced transdermal delivery of lidocaine cream via ultrasound and microneedle rollers by Jiaxiao Sun, Yang Yang, Yang Yang, Juanjuan Zheng, Hao Liang, Feng Yan, Wensheng Zhang, Wensheng Zhang, Wenqin Xie

“…In vivo findings corroborated these results, with the combined method facilitating the most rapid onset of anesthesia (mean onset time 28.75 ± 6.41 min, p < 0.05 vs control 67.50 ± 4.63 min) and improved transdermal delivery compared to other groups, achieving 100% anesthetic efficiency rate at 60 min vs. 25% in control.ConclusionMicroneedle rollers demonstrate superior clinical efficacy over ultrasound, enabling rapid lidocaine delivery (15-min onset ex vivo; 32.5-min anesthesia in vivo) and achieving 100% anesthetic efficiency for time-sensitive procedures—establishing a practical paradigm shift in transdermal local anesthesia.…”
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Optilume drug‐coated balloon for anterior urethral stricture: 2‐year results of the ROBUST III trial by Maia E. VanDyke, Allen F. Morey, Karl Coutinho, Kaiser J. Robertson, Richard D'Anna, Kent Chevli, Christopher H. Cantrill, Michael J. Ehlert, Alexis E. Te, Jeffrey Dann, Jessica M. DeLong, Ramón Virasoro, Judith C. Hagedorn, Richard Levin, Euclid DeSouza, David DiMarco, Brad A. Erickson, Carl Olsson, Sean P. Elliott

“…Primary safety endpoint was freedom from serious procedure‐ or device‐related adverse events (AEs). …”
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Postoperative hepatitis B virus reactivation and its impact on survival in HBV-related hepatocellular carcinoma patients undergoing conversion therapy with interventional therapy c... by Shaowei Xu, Qingqing Pang, Meng Wei, Danxi Liu, Du Yuan, Tao Bai, Xiaobo Wang, Zhihong Tang, Feixiang Wu

“…The therapeutic regimen consisted of interventional procedures (hepatic artery infusion chemotherapy [HAIC] and/or transarterial chemoembolization [TACE]) combined with tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs).MethodsA retrospective analysis was performed at a single institution involving 91 patients who had initially unresectable HCC linked to the hepatitis B virus. …”
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A qualitative analysis on the awareness of noise pollution and occupational protection among staff members of the Central Sterile Supply Department (消毒供应中心工作人员对噪声污染的认知及职业防护质性分析)... by HUANG Xuanxuan (黄玄玄), FU Li (付立), SUN Ziwen (孙子文), YU Jiang (于江), ZHANG Shenhong (张沈弘), ZHANG Tianqiang (张天强)

“…The interview data were analyzed using the Colaizzi 7-step procedure of phenomenological analysis. Results Extract three themes as follows: Firstly, the staff in the Central Sterile Supply Department showed low attention to noise pollution; secondly, they had a relatively low awareness of the hazards of noise; thirdly, they lacked noise protection measures and the staff's compliance with such measures was also poor. …”
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