Clinical evaluation of two pathogen enrichment approaches for next-generation sequencing in the diagnosis of lower respiratory tract infections by Xiao Lei, Xiumei Xu, Chao Liu, Lipeng Zhong, Shupeng Yin, Biaoxian Li, Ling Cao, Zhiting Xie, Jing Li, Xuan Zhang, Yaping Guo, Liang Zhang, Haiyan Lin, Sufeng Zhang, Chengsheng Zhang, Tian Gong

“…This study demonstrated that ps-tNGS achieved a better overall diagnostic performance and may potentially replace bs-tNGS in the clinical application.IMPORTANCEMicrobial enrichment in metagenomic next-generation sequencing has been achieved through differential cell lysis, but the results varied, depending on experimental procedures and sample types. Therefore, direct enrichment of pathogen DNA/RNA was attempted via multiplex PCR or hybrid probe capture (targeted next-generation sequencing [tNGS]). …”
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Real-World Evaluation of Demographics, Treatment Pattern, and Economic Burden of Heart Failure and Kidney Disease in Type 2 Diabetes Mellitus Patient Population in Dubai, United Ar... by Alaaeldin Bashier, Mohamed Farghaly, Juwairia Yousif Alali, Amna Khalifa AlHadari, Yasmin Ajaz, Vani Krishna Warrier, Elamin Abdelgadir, Muhammad Hamed Farooqi, Sana Qamar, Mohamed Alsayed, Mohamed Samir Fahmy, Dali Tannouri, Arun Jayarame Gowda, Nancy Syed Awad, Badarinath Chickballapur Ramachandrachar, Ashok Natarajan

“…The median cost for drugs and procedures was highest in cohort 5 (4,525 [range, 38–31,546] AED and 2,297 [range, 56–105,074] AED, respectively). …”
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Future liver remnant hypertrophy and postoperative outcomes: a retrospective comparison between segmental and main right portal vein embolization by Elif Can, Aboelyazid Elkilany, Sophia Paparoditis, Bernhard Gebauer, Dominik Geisel, Felix Krenzien, Anne Pohrt, Wibke Uller, Michael Doppler, Sebastian Ebel, Holger Gößmann, Uli Fehrenbach

“…Conclusion Selective segmental right portal vein embolization, sparing the main right portal vein, offers a safe and effective alternative to MRPVE, achieving comparable FLR hypertrophy while potentially simplifying intraoperative procedures and reducing postprocedural complications. …”
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MALDI-TOF lipidomics rapidly detects modification of 2-hydroxymyristate lipid A, a potential virulence trait in Enterobacter bugandensis by Rémy A. Bonnin, Aymeric Jacquemin, Jade Pizzato, Delphine Girlich, Cecile Emeraud, Markus Kostrzewa, Thierry Naas, Gerald Larrouy-Maumus, Laurent Dortet

“…Rapid identification of lipid A modification might help clinicians to adapt procedures when an Enterobacter spp. is identified in newborns.IMPORTANCEEnterobacter bugandensis is now recognized as a potential threat in neonatal wards due to its ability to survive in incubators and its virulence properties. …”
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Risk factors of cervical insufficiency in women with PCOS undergoing IVF-ET treatment: a case-control study by Xueqing Zhao, Xueqing Zhao, Xueqing Zhao, Xueqing Zhao, Xueqing Zhao, Shenglong Ye, Xin Yan, Rong Li, Rong Li, Rong Li, Rong Li, Rong Li, Yongqing Wang, Yongqing Wang, Yongqing Wang, Yongqing Wang, Yongqing Wang

“…In contrast, for women with PCOS undergoing frozen embryo transfer, multiple factors including BMI (OR=1.254, 95% CI: 1.134-1.388, P<0.001), AMH levels (OR=1.232, 95% CI: 1.144-1.327, P<0.001), frequency of hysteroscopy procedures (OR=1.603, 95% CI: 1.155-2.224, P=0.005) and prior gravidity (OR=2.423, 95% CI: 1.674-3.508, P<0.001), were associated with an increased risk of CI.ConclusionThe study analysed risk factors for cervical insufficiency in women with PCOS who underwent IVF-ET treatment, such as BMI, AMH, frequency of hysteroscopy operations, prior gravidity, twin pregnancy. …”
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Evaluation of a novel Aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis by Yajie Lu, Huanhuan Zhong, Huanhuan Zhong, Yujie Wang, Chao Sun, Yuanyuan Li, Yuchen Cai, Xiaomin Cai, Jiamei Wang, Jinjin Zhong, Xin Su

“…The “any-positive” strategy of combined diagnosis with Aspergillus IgG LFA serves as a valuable supplement to current diagnostic approaches, particularly benefiting patients who cannot tolerate invasive bronchoscopic procedures.…”
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Scleral Thickness in Eyes with Pachychoroid Pigment Epitheliopathy Accompanied by Keratoconus by Paolo Forte, MD, Alessandro Feo, MD, Hideki Koizumi, MD, PhD, Enrico Borrelli, MD, PhD, Riccardo Manocchio, MD, Luca Di Cello, MD, PhD, Francesco Biagini, MD, Francesco Macocco, MD, Gabriele Drago, MD, Giovanni Forte, MD, Aldo Vagge, MD, PhD, Christian Gianoglio, PhD, Vincenzo Fontana, PhD, Michele Iester, MD, PhD, Massimo Nicolò, MD, PhD, Mario R. Romano, MD, PhD, Chiara Bonzano, MD, PhD

“…To accommodate for the potential clustering effect due to within-patient correlated eye data, a generalized estimating equation procedure was applied to regression analysis. Additionally, a decision tree machine learning model with K-fold cross-validation was employed to predict PPE. …”
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Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…Compared to their previous ablation or excision treatments, participants found 5FU to be less painful, and all would prefer a self-administered treatment instead of a procedure if it were an option.ConclusionSelf-administered intravaginal 5FU as an adjuvant treatment for cervical precancer among women living with HIV in Kenya was highly acceptable. …”
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Surgical and Neurological Outcomes in Robotic Thymectomy for Myasthenic Patients with Thymoma by Khrystyna Kuzmych, Dania Nachira, Amelia Evoli, Raffaele Iorio, Carolina Sassorossi, Maria Teresa Congedo, Gregorio Spagni, Alessia Senatore, Giuseppe Calabrese, Stefano Margaritora, Elisa Meacci

“…Results: Thirty-nine (70.9%) procedures were performed using the left-sided approach. …”
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Exploring the standardized detection and sampling methods of human nasal SARS-CoV-2 RBD IgA by Xuanxuan Zhang, Xuanxuan Zhang, Jizong Jia, Chaoying Hu, Chaoying Hu, Yulong Fu, Guanxing Liu, Yajing Li, Qian He, Qian He, Fan Gao, Fan Gao, Na Li, Lina Wang, Jianping Chu, Henggang Xu, Zhihao Fu, Zhihao Fu, Hui Zhao, Hui Zhao, Zhenglun Liang, Zhenglun Liang, Jingxin Li, Miao Xu, Miao Xu, Qunying Mao, Qunying Mao

“…Following the scientific guidelines (Q14 and Q2(R2)) for analytical procedure development and validation released by the International Council for Harmonization (ICH), an ELISA for nasal SARS-CoV-2 WT-RBD specific IgA detection was established and validated. …”
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Systemic immune-inflammatory index predicts fragility fracture risk in postmenopausal anemic females with type 2 diabetes mellitus: evidence from a longitudinal cohort study by Dinggui Huang, Qi He, Jiangmei Pan, Zhenwei Zhai, Jingxia Sun, Qiu Wang, Wenxin Chu, Jianhao Huang, Jinming Yu, Xiaoqin Qiu, Wensheng Lu

“…Therefore, monitoring the SII and hemoglobin in postmenopausal older women with T2DM is helpful in routine clinical practice to identify individuals at high risk for fragility fractures and to promptly execute appropriate fracture intervention procedures.…”
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Cost-effectiveness of angiographic quantitative flow ratio-guided coronary intervention: A multicenter, randomized, sham-controlled trial by Yanyan Zhao, Changdong Guan, Yang Wang, Zening Jin, Bo Yu, Guosheng Fu, Yundai Chen, Lijun Guo, Xinkai Qu, Yaojun Zhang, Kefei Dou, Yongjian Wu, Weixian Yang, Shengxian Tu, Javier Escaned, William F. Fearon, Shubin Qiao, David J. Cohen, Harlan M. Krumholz, Bo Xu, Lei Song, On behalf of FAVOR III China Study Group, Ting Gao

“…During the two-year follow-up, data were collected on clinical outcomes, quality-adjusted life-years (QALYs), estimated costs of index procedure hospitalization, outpatient cardiovascular medication use, and rehospitalization due to major adverse cardiac and cerebrovascular events (MACCE). …”
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Effects of postbiotic products from Saccharomyces cerevisiae fermentation on lactation performance, antioxidant capacity, and blood immunity in transition dairy cows by Dongwen Dai, Fanlin Kong, Haoqi Han, Weina Shi, Han Song, Ilkyu Yoon, Shuo Wang, Xiaojing Liu, Na Lu, Wei Wang, Shengli Li

“…Data were analyzed using the MIXED procedure in SAS (SAS Institute Inc.). All data were subjected to repeated measures ANOVA. …”
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Oral–gut microbiome axis in a Korean cohort with inflammatory bowel disease and ankylosing spondylitis (INTEGRATE): a prospective and observational study protocol by June-Young Lee, Tae-Hwan Kim, Sungsin Jo, Yeon-Ah Lee, Sang Won Lee, Chang Kyun Lee, Bora Nam, Soo-Kyung Park, Hyun Sik Kim, Bo-Hyung Kim, Shin Ju Oh, Jae-Yun Lee, Dong Il Park

“…Our research team will provide detailed information about the study, including an information sheet explaining its aims and procedures, prior to enrolment. Prospective participants will be informed that they have the right to withdraw from the study at any time, without penalty. …”
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SET OF ORGANIZATIONALLY-DIDACTIC CONDITIONS OF THE MODEL OF STUDENTS’ AUTONOMY DEVELOPMENT SYSTEM IMPLEMENTATION by Roman A. Popov

“…Including into the autonomous educational activities structural logical schemes; values-oriented exercises; creative work based upon the choice mechanism; cognitive situation-specific tasks, whose solution procedure is constructed according to the increase of the comprehensiveness; problematicity; novelty; interdisciplinary relations and creativity secures the achievement of positive result in the process of autonomy formation. …”
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KONTRAKT SPÓŁKI JAKO PODSTAWA ODPOWIEDZIALNOŚCI IN SOLIDUM W PRAWIE RZYMSKIM by Zuzanna Służewska

“…Such a solution was necessary because of the purely consensual character o f the Roman partnership and the lack of any formal procedure of its conclusion and dissolution. The existence of that contract could not affect the model of the external liability of partners, because it would be too risky for third parties, which had no possibility to make sure if a contract of partnership between some persons had been actually concluded or not. …”
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Methanolic stem-bark extracts of Adansonia digitata modulates haematological and antioxidant parameters in streptozotocin-induced diabetic rats by Ojochenemi Ejeh Yakubu, Chukwuma Stephen Ezeonu, David Ata Agyo, Tsuvini Jonah, Ebenezer Morayo Ale

“…This study investigates the effects of methanolic stem-bark extracts of Adansonia digitata on haematological and antioxidant status in streptozotocin-induced diabetic rats. Experimental Procedure: Fourty-two wistar rats were distributed into 6 groups of 7 each. …”
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Calidad de la atención en podología universitaria. Análisis del cuestionario de satisfacción del paciente by Fátima Santalla Borreiros, Ramón González Cabanach, Manuel Romero-Soto, Antonio Souto-Gestal

“…The best-rated factors were “Care”, “Procedures” and “Clinical aspects”.’ Item correlations showed some differences from the original study, highlighting a strong correlation between care received and staff friendliness. …”
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Analysis of the patients' quality of life after radical cystectomy with the orthotopic neobladder or ileal conduit formation by S. V. Kotov, A. L. Khachatryan, D. P. Kotova, A. K. Zhuravleva, Sh. M. Sargsyan, D. M. Magomedov

“…The median follow-up period for patients from the completed surgical procedure to the survey was 7 months (4.5 - 9.5 months). …”
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Engineered Porosity ZnO Sensor Enriched with Oxygen Vacancies Enabled Extraordinary Sub-ppm Sensing of Hydrogen Sulfide and Nitrogen Dioxide Air Pollution Gases at Low Temperature... by Engin Ciftyurek, Zheshen Li, Klaus Schierbaum

“…We were able to create an open porosity network throughout the ZnO microstructure and simultaneously achieve an abundance of oxygen vacancies by using a heat treatment procedure. Surface chemistry and oxygen vacancy content in ZnO were examined using XPS and AES. …”
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