Advanced airway interventions for paediatric cardiac arrest: updated systematic review and meta-analysis by Jason Acworth, Jimena del Castillo, Elliott Acworth, Lokesh Tiwari, Jesus Lopez-Herce, Eric Lavonas, Laurie Morrison, Barnaby R. Scholefield

“…Placement of an advanced airway device may facilitate more effective resuscitation than bag-mask ventilation but requires more skilled personnel and the time taken to perform the procedure may interfere with other vital components of resuscitation. …”
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Key indicators for guiding tocilizumab therapy to prevent orbital decompression surgery in hormone-resistant dysthyroid optic neuropathy by Wenjun Shu, Wenjun Shu, Wenjun Shu, Wenjun Shu, Mingxu Yan, Mingxu Yan, Mingxu Yan, Mingxu Yan, Lu Gan, Lu Gan, Lu Gan, Lu Li, Hongyue Tao, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Jinghan Wang, Jinghan Wang, Jinghan Wang, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Xintong Lin, Xintong Lin, Xintong Lin, Haifeng Chen, Haifeng Chen, Haifeng Chen, Jie Guo, Jie Guo, Jie Guo, Kang Xue, Kang Xue, Kang Xue, Hongguang Cui, Heng Lou, Heng Lou, Heng Lou, Binbin Xu, Binbin Xu, Binbin Xu, Jinwei Cheng, Jinwei Cheng, Jinwei Cheng, Hongying Ye, Yiming Li, Jiang Qian, Jiang Qian, Jiang Qian, Rui Zhang, Rui Zhang, Rui Zhang, Ruiqi Ma, Ruiqi Ma, Ruiqi Ma, Fangfang Zeng

“…These indicators assist in the personalization of TCZ therapy and in the avoidance of unnecessary surgical procedures.…”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…Abstract Background: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedures. Here, we present naturally occurring exosomes (EXOs) isolated from amniotic fluid-derived MSCs (AF-MSCs) and their mimetic analogs (MIMs) as viable, reproducible, and stable alternatives. …”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early by Mariangela Morelli, Francesca Lessi, Serena Barachini, Serena Barachini, Romano Liotti, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti

“…The number of MGMT gene promoter methylated tumors was higher in the responsive group, as expected, however, some non-methylated tumor cases turned out to be nevertheless responsive to TMZ, suggesting that our procedure could be synergistic with the classical MGMT methylation biomarker.ConclusionsFor the first time, FLIM-based metabolic imaging was used on live glioblastoma organoids. …”
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Increasing the meaningful involvement of women in HIV cure-related research: a qualitative interview study in the United States by Karine Dubé, Elizabeth Barr, Morgan Philbin, Amaya Perez-Brumer, Brian Minalga, Beth Peterson, Dawn Averitt, Bridgette Picou, Krista Martel, Cecilia Chung, María Mejía, Martha Cameron, Gail Graham, Lynda Dee, Dázon Dixon Diallo, Ebony Gordon, Anastasia Korolkova, Typhanye Dyer, Judith D. Auerbach, Eileen Scully, Krista L. Dong, Sara Gianella

“…Participants noted that women would be willing to participate in HIV cure trials, related procedures (e.g. biopsies), and analytical treatment interruptions. …”
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The use and impact of surveillance-based technology initiatives in inpatient and acute mental health settings: a systematic review by Jessica L. Griffiths, Katherine R. K. Saunders, Una Foye, Anna Greenburgh, Ciara Regan, Ruth E. Cooper, Rose Powell, Ellen Thomas, Geoff Brennan, Antonio Rojas-García, Brynmor Lloyd-Evans, Sonia Johnson, Alan Simpson

“…If they are to be implemented, all key stakeholders should be engaged in the development of policies, procedures and best practice guidance to regulate their use, prioritising patients’ perspectives.…”
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A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry by Johannes Leiner, Sebastian König, Anne Nitsche, Sven Hohenstein, Jana Nagel, Melchior Seyfarth, Henning Baberg, Alexander Lauten, Hans Neuser, Alexander Staudt, Jürgen Tebbenjohanns, René Andrié, Michael Niehaus, Markus W. Ferrari, Ralf Kuhlen, Andreas Bollmann

“…Data collection is based on a set of variables following recommendations of the International Consortium of Health Outcome Measurements (ICHOM) covering data on demographics, medical history, HF characteristics, medication, procedures, and patients' perceived health status via the collection of standardized PROs. …”
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Microsurgical Clipping of Unruptured Middle Cerebral Artery Bifurcation Aneurysms: A Single-Center Experience by Nico Stroh-Holly, Philip Rauch, Harald Stefanits, Philipp Hermann, Helga Wagner, Michael Sonnberger, Maria Gollwitzer, Stefan Aspalter, Andreas Gruber, Matthias Gmeiner

“…Conclusions: The findings indicate that microsurgical clipping is a safe procedure with minimal need for retreatment. It achieves a high occlusion rate while maintaining a very low rate of adverse outcomes. …”
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Clinical review and drug sensitivity test of Corynebacterium kroppenstedtii complex isolates in non-lactating patients with severe mastitis by Zuxin Liang, Zhujun Zeng, Zhujun Zeng, Yanqiang Liao, Yaxin Cao, Dongmei Li, Ningbo Deng, Yeyan Lei, Xuanhui Long, Chenguang Shen, Chenguang Shen, Rui Xu

“…The micro broth dilution method is not applicable for EUCAST drug susceptibility testing for CKC and there is no suitable drug susceptibility evaluation procedure for daptomycin against CKC.…”
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Enhancing needle puncture detection using high-pass filtering and diffuse reflectance by Rachael L’Orsa, Rachael L’Orsa, Rachael L’Orsa, Rachael L’Orsa, Anupam Bisht, Linhui Yu, Kartikeya Murari, Kartikeya Murari, Kartikeya Murari, Garnette R. Sutherland, Garnette R. Sutherland, David T. Westwick, Katherine J. Kuchenbecker

“…Very high failure rates (up to 94.1%) have been reported for pre-hospital needle decompression, however, and the procedure can result in the accidental puncture of critical thoracic tissues because it is performed blind. …”
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Disproportionate impact of the COVID-19 pandemic on socially vulnerable communities: the case of Jane and Finch in Toronto, Ontario by Zahra Movahedi Nia, Zahra Movahedi Nia, Zahra Movahedi Nia, Cheryl Prescod, Michelle Westin, Patricia Perkins, Patricia Perkins, Mary Goitom, Mary Goitom, Kesha Fevrier, Kesha Fevrier, Sylvia Bawa, Sylvia Bawa, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong, Jude Dzevela Kong

“…ObjectiveThis work aims to study the disproportionate impact of the COVID-19 pandemic on the Jane and Finch community, one of the socially vulnerable neighborhoods in the Greater Toronto Area (GTA), Ontario, Canada, in terms of morbidity, mortality, and healthcare services.MethodologyA dataset provided by the Black Creek Community Health Centre (BCCHC), gathered from different health-related portals, covering various health statistics during COVID-19, namely, COVID-19 number of cases, hospitalizations, deaths, percentage of vaccination with one-, two-, and three-dose(s), Primary and Preventive Care (PPC) visits which include fecal and pap-smear cancer tests, and percentage of completed Imaging, Procedures, and Surgeries (IPS) which include the number of patients waiting for surgery were studied using statistical analysis. …”
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Acridocarpus smeathmannii root extracts inhibit human prostate and bladder smooth muscle contraction, porcine arterial vasoconstriction, and cytotoxicity of prostate stromal cells by Oluwafemi Ezekiel Kale, Sheng Hu, Claudia Huber, Felix Schierholz, Anna Ciotkowska, Alexander Tamalunas, Christian G. Stief, Wolfgang Eisenreich, Martin Hennenberg

“…In this study, we investigated the bioactivity-guided effects of Acridocarpus smeathmannii on smooth muscle contractility using human tissues obtained from radical prostatectomy and cystectomy procedures, as well as porcine coronary and interlobar arteries. …”
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Step-by-step: Intra-arterial renal hypothermia during robot-assisted partial nephrectomy by Joris Vangeneugden, Pieter De Backer, Camille Berquin, Saar Vermijs, Peter Dekuyper, Alexandre Mottrie, Charlotte Debbaut, Thierry Quackels, Charles Van Praet, Karel Decaestecker

“…Patients and surgical procedure: Ten patients with complex renal masses (deep endophytic, hilar, multiple ipsilateral and very large lesions), where clamping times over 25 min were expected, were treated with RAPN using IAC between March 2020 and March 2023 in 3 referral centers by 2 surgeons. …”
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Integrating the GRACE Score with the Ceramide Risk Score Enhances the Predictive Accuracy of Major Adverse Cardiac Events in Patients with Acute Coronary Syndrome Undergoing Percut... by Xiaofei Wang, Chengzhe Liu, Fu Yu, Zizhuo Zhang, Jiale Wang, Xiaoyu Shi, Tianyou Xu, Qiang Deng, Liping Zhou, Wanyue Sang, Hong Jiang, Lilei Yu

“…MACE was defined as the recurrence of non-fatal acute myocardial infarction, repeat coronary revascularization procedures (PCI or coronary artery bypass grafting, CABG), or death excluding the initial event qualifying the patient for the study. …”
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Gender related outcome differences in off-pump coronary artery bypass grafting by Riswan Akram, Friedrich Sobik, Tim Knochenhauer, Sebastian A. Philipp, Jens Brickwedel, Xiaoqin Hua, Beate Reiter, Svante Zipfel, Yvonne Schneeberger, Evaldas Girdauskas, Evaldas Girdauskas, Hermann Reichenspurner, Bjoern Sill, Andreas Schaefer

“…In female patients less utilization of both internal mammary arteries was documented (502/880, 57.04% vs. 74/195, 37.94%; p < 0.001). Procedure time (256.13 min vs. 238.02 min; p < 0.001) and number of distal anastomoses (2.40 ± 0.83 vs. 2.11 ± 0.82; p < 0.001) were lower in female patients. 30-day mortality (16/880, 0.34% vs. 4/195, 0.51%; p = 0.77) and rates of disabling stroke (3/880, 1.81% vs. 1/195, 2.05%; p = 0.55) were similar between groups. …”
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Utility of Noninvasive Testing Before Invasive Coronary Angiography in the Assessment for Revascularization by Simon Parlow, MD, Richard G. Jung, MD, PhD, Pietro Di Santo, MD, Joanne Joseph, MD, Stephanie Skanes, MD, Omar Abdel-Razek, MD, Graeme Prosperi-Porta, MSc, MD, Pouya Motazedian, MD, Michael Froeschl, MSc, MD, Marino Labinaz, MD, Rebecca Mathew, MD, F. Daniel Ramirez, MSc, MD, Trevor Simard, MD, PhD, Benjamin Hibbert, MD, PhD

“…Results: Of the 17,181 individual procedures, 2183 were included. Positive CTA had an odds ratio (OR) of 2.68 (95% CI, 1.82-3.94) for revascularization and positive MPI an OR of 1.29 (95% CI, 1.07-1.56). …”
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Case Report: Hydroa vacciniforme-like lymphoproliferative disorder, an EBV-associated disease, successfully treated with hematopoietic stem cell transplantation by Eduardo Liquidano-Perez, Eduardo Liquidano-Perez, Gibert Maza-Ramos, Marco Yamazaki-Nakashimada, Rodolfo Rodríguez-Jurado, Alfonso G. Ramírez Ristori, Juan Carlos Bustamante-Ogando, Mario Ernesto Cruz-Munoz, Arturo Gutierrez-Guerrero, Marimar Saez-de-Ocariz, Sara Espinosa-Padilla, Nideshda Ramirez-Uribe, Selma C. Scheffler-Mendoza

“…Further investigations revealed persistent EBV infection and lymphoma; hence, a haploidentical stem cell transplant was performed at 15. The procedure was successful, achieving complete immune reconstitution and viral clearance. …”
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Evaluation of grip strength in hook of hamate fractures treated with osteosynthesis. Is this surgical treatment necessary? by Claudia Lamas-Gómez, Laura Velasco-González, Aranzazu González-Osuna, Marta Almenara-Fernández, Luis Trigo-Lahoz, Xavier Aguilera-Roig

“…Objective: The aim of this study was to evaluate the outcomes of open reduction and internal fixation (ORIF) in hamate hook fractures and review the literature on this surgical procedure. Methods: We report the outcomes of ORIF of hamate hook fractures in 13 consecutive patients (12 men and 1 woman; mean age: 32 years (range, 22–48 years)). …”
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Cognitive Dysfunction in the Addictions (CDiA): protocol for a neuron-to-neighbourhood collaborative research program by Yuliya S. Nikolova, Yuliya S. Nikolova, Yuliya S. Nikolova, Anthony C. Ruocco, Anthony C. Ruocco, Anthony C. Ruocco, Anthony C. Ruocco, Daniel Felsky, Daniel Felsky, Daniel Felsky, Shannon Lange, Shannon Lange, Shannon Lange, Shannon Lange, Thomas D. Prevot, Thomas D. Prevot, Thomas D. Prevot, Erica Vieira, Erica Vieira, Daphne Voineskos, Daphne Voineskos, Jeffrey D. Wardell, Jeffrey D. Wardell, Jeffrey D. Wardell, Jeffrey D. Wardell, Daniel M. Blumberger, Daniel M. Blumberger, Kevan Clifford, Kevan Clifford, Ravinder Naik Dharavath, Philip Gerretsen, Philip Gerretsen, Ahmed N. Hassan, Ahmed N. Hassan, Ingrid M. Hope, Samantha H. Irwin, Sheila K. Jennings, Sheila K. Jennings, Bernard Le Foll, Bernard Le Foll, Osnat Melamed, Osnat Melamed, Josh Orson, Peter Pangarov, Leanne Quigley, Cayley Russell, Kevin Shield, Kevin Shield, Kevin Shield, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Matthew E. Sloan, Ashley Smoke, Ashley Smoke, Victor Tang, Victor Tang, Victor Tang, Diana Valdes Cabrera, Diana Valdes Cabrera, Wei Wang, Samantha Wells, Samantha Wells, Samantha Wells, Rajith Wickramatunga, Etienne Sibille, Etienne Sibille, Etienne Sibille, Lena C. Quilty, Lena C. Quilty

“…Here, we introduce the design and procedures underlying Cognitive Dysfunction in the Addictions (CDiA), an integrative research program, which aims to fill these knowledge gaps and facilitate research discoveries to enhance treatments for people living with SUDs. …”
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Roles of private healthcare facilities in post-test counselling and referral for HIV services during antenatal care in South-West Nigeria by Henry Osaro Aisagbonhi, Yejide Olukemi Oseni, Mayowa Omolabake Odofin, Ezioma Anne Chukwu, Ukamaka Gladys Okafor, Ifeoluwa Silvanus Abiodun, Treasure Wariboko Obiajulu Okoye, Oluwadamilola Aminat Sadare, Eugenia Onwuchuluba Ebele, Esther Ametor Ajakaiye, Azeezat Abimbola Oyewande

“…Most facilities with screening services had written counselling procedures (64.7%), disclosed HIV status immediately (71.8%), and further supported patients with referral services (93.5%). …”
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